Localized tracheal amyloidosis incidentally detected during lung cancer screening with low-dose chest computed tomography

Gorospe, L.; Arrieta, P.; Barrios-Barreto, D.

doi:10.1016/j.rceng.2019.05.018

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The histopathology of the nodule obtained during bronchoscopy revealed expansion of the submucosal stroma, mostly of amorphous eosinophilic material, which was positive for Congo red staining, showing apple-green birefringence when exposed to polarized light. Systemic amyloidosis was biochemically and radiologically ruled out. Given the absence of symptoms, we agreed with the patient to conduct a “watch-and-wait” follow-up.<elsevierMultimedia ident="fig0005"></elsevierMultimedia>Amyloidosis is an idiopathic disease characterized by the extracellular accumulation of insoluble fibrillar proteins (amyloid) in organs and tissues. Amyloidosis can present as a systemic disease (associated with high morbidity and mortality) or occur in certain organs (mainly the kidneys, heart and liver). Tracheal amyloidosis is very uncommon, and its therapeutic objective consists of maintaining adequate tracheal patency with hydrostatic balloon dilation, endoscopic excision or open surgery. To our knowledge, this is the first report of a localized form of tracheal amyloidosis detected accidentally during screening for lung cancer using low-dose CT." "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2019-04-25" "fechaAceptado" => "2019-05-14" "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "Please cite this article as: Gorospe L, Arrieta P, Barrios-Barreto D. Amiloidosis traqueal localizada detectada casualmente durante el cribado de cáncer de pulmón mediante TC de baja dosis. Rev Clin Esp. 2021;221:309–310." ] ] "multimedia" => array:1 [ 0 => array:6 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1915 "Ancho" => 2167 "Tamanyo" => 262161 ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/22548874/0000022100000005/v3_202105110748/S225488741930253X/v3_202105110748/en/main.assets" "Apartado" => array:4 [ "identificador" => "71811" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Medicine in images" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/22548874/0000022100000005/v3_202105110748/S225488741930253X/v3_202105110748/en/main.pdf?idApp=WRCEE&text.app=https://revclinesp.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S225488741930253X?idApp=WRCEE"]

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Vol. 221. Issue 5.

Pages 309-310 (May 2021)

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