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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">A 34-year-old woman was diagnosed with multiple myeloma in 2014&#44; with complete response&#46; In December 2017&#44; the patient underwent positron emission tomography with 2-deoxy-2-&#91;fluorine-18&#93;fluoro- <span class="elsevierStyleSmallCaps">d</span>-glucose integrated with computed tomography &#40;<span class="elsevierStyleSup">18</span>F-FDG PET&#47;CT&#41; for an evaluation prior to a possible allogeneic transplant&#44; which revealed as the only finding a hypermetabolic nodule in the right breast &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46; An assessment was therefore recommended to rule out malignancy&#46; Histopathology confirmed the presence of infiltration by multiple myeloma&#46; Faced with the presence of a breast plasmacytoma&#44; the decision was made to perform allogeneic transplantation and subsequent radiation therapy&#46; A check-up PET&#47;CT was requested to assess the treatment response of the breast plasmacytoma&#44; which revealed metabolic progression of the disease with involvement of muscle&#44; supradiaphragmatic and infradiaphragmatic lymph nodes&#44; liver&#44; kidneys and bone &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>A&#41;&#46; The patient was started on systemic chemotherapy&#46; Once the treatment was completed&#44; the patient underwent a new PET&#47;CT&#44; which showed a partial metabolic response of the lesions &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>B&#41;&#46; After changing the treatment line and after several hospitalizations for infectious conditions&#44; the patient ultimately died&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">Breast plasmacytoma is a rare entity but is most common in women with a mean age of 53 years&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> The disease can be its own presentation or occur during the course of already diagnosed multiple myeloma&#46;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> As was the case with our patient&#44; breast plasmacytoma can also precede a systemic relapse of a treated disease in remission&#46; It is therefore important to consider this finding because it can be a manifestation prior to the relapse of multiple myeloma&#46;</p></span>"
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April 2021 Breast plasmacytoma as a manifestation prior to relapse of multiple myeloma
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Vol. 221. Issue 4.
Pages 243-244 (April 2021)
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Vol. 221. Issue 4.
Pages 243-244 (April 2021)
Medicine in Images
DOI: 10.1016/j.rceng.2019.03.031
Breast plasmacytoma as a manifestation prior to relapse of multiple myeloma
Plasmocitoma mamario como manifestación previa a recaída de mieloma múltiple
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E. López Rodríguez
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estefania.lr.86@gmail.com

Corresponding author.
, R.M. Álvarez Pérez, J.M. Jiménez-Hoyuela García
Servicio de Medicina Nuclear. Hospital Universitario Virgen del Rocío, Sevilla, Spain
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