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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">An 82-year-old man with no personal history of interest was admitted for a papula in the nasal area that bled easily&#46; In terms of family history&#44; one of the patient&#8217;s children experienced 6 episodes of pneumothorax&#44; which was ultimately resolved with pleurodesis&#46; During the physical examination &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#44; we observed a papular lesion with a scab in the right nasal ala &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>B&#41;&#46; We observed multiple translucent&#44; skin-colored papules distributed in a generalized manner over the rest of the face &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>A&#41;&#46; The patient reported that they had appeared over the past year&#46; The histopathology results were compatible with fibrofolliculoma&#46; We requested thoracoabdominal computed tomography&#44; which showed numerous cystic lesions in both kidneys&#44; associated with a larger tumor mass&#46; The lung parenchyma showed no associated lesions&#46; The patient was referred to the oncology department for study and treatment&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">Birt-Hogg Dub&#233; syndrome is an uncommon&#44; autosomal dominant disease that usually starts in adulthood&#46; Although its etiology is unknown&#44; the disease has been reported in relation to a mutation of the FLCN gene in chromosome 17p22&#46; This gene encodes folliculin&#44; which is suspected to participate in the mTOR pathway and is mainly implicated in the development of renal tumors&#46; The rapid onset of multiple facial papules&#44; whose histopathological diagnosis is fibrofolliculoma&#44; requires physicians to rule out the presence of internal organ tumors&#44; especially in the kidneys&#46; A personnel or family history of pneumothorax should alert clinicians to this condition&#44; given that pulmonary cysts are another manifestation of this syndrome&#46; The prognosis depends on the presence of malignant tumors&#44; given that skin lesions are indolent&#46;</p></span>"
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Vol. 221. Issue 1.
Pages 66-67 (January 2021)
Medicine in Images
DOI: 10.1016/j.rceng.2019.07.012
Asymptomatic eruptive facial papules
Pápulas asintomáticas eruptivas faciales
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F.J. Navarro-Triviño
Servicio de Dermatología y Venereología, Hospital Universitario San Cecilio, Granada, Spain
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