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    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0065">Introduction</span><p id="par0005" class="elsevierStylePara elsevierViewall">Acute heart failure &#40;AHF&#41; is one of the main causes of hospitalization in Spain<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> and is responsible for one of the largest economic and healthcare burdens on any public health system&#46;<a class="elsevierStyleCrossRefs" href="#bib0010"><span class="elsevierStyleSup">2&#44;3</span></a> It is associated with high in-hospital mortality and high readmission rates following discharge&#46;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> In Spain&#44; like in many countries with public health systems&#44; the great majority of patients with AHF are initially treated in hospital emergency departments &#40;HED&#41; and nearly three-fourths of them are hospitalized&#46; Given the multidisciplinary nature of the medical care for this syndrome&#44; many departments receive patients with AHF and general medicine departments are those that admit the vast majority of them&#46;<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">For more than a decade&#44; home hospitalization &#40;HH&#41; has been an alternative to conventional hospitalization that makes it possible to provide the same level of care&#44; but in the patient&#8217;s home&#46; This option allows for in-person monitoring by physicians and nurses&#44; performing certain additional tests&#44; and administering intravenous medication&#46; A meta-analysis has demonstrated that HH increases the time to readmission&#44; reduces costs&#44; and improves quality of life in patients with AHF who require hospital admission&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a> The majority of these outcomes come from studies that select patients both in emergency departments and in conventional wards or clinics&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a> In recent years&#44; there has been growing use of HH in patients transferred directly from HED after a few hours of observation and without prior conventional hospitalization&#46; Therefore&#44; this work aims to study the frequency&#44; profile&#44; and short-term outcomes of patients with AHF transferred to HH and compare them to those hospitalized in short-stay units &#40;SSU&#41; and internal medicine wards &#40;IM&#41;&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0070">Methods</span><p id="par0015" class="elsevierStylePara elsevierViewall">The EAHFE &#40;<span class="elsevierStyleItalic">Epidemiology of Acute Heart Failure in Emergency departments</span>&#41; Registry is a multipurpose&#44; multicentric prospective cohort study that includes 18&#44;370 patients&#46; It has had six patient enrollment phases to date in which 45 Spanish HED have participated &#40;13&#37; of the 339 public hospitals&#44; including university&#44; referral&#44; and regional hospitals&#41;&#46; Specific details on the EAHFE Registry have been published in previous studies&#46;<a class="elsevierStyleCrossRefs" href="#bib0025"><span class="elsevierStyleSup">5&#8211;8</span></a></p><p id="par0020" class="elsevierStylePara elsevierViewall">This work is an exploratory study that selected patients in the registry from hospitals that had transferred patients with AHF directly to HH following care in the emergency department&#46; Only the EAHFE-4 &#40;2014&#41;&#44; EAHFE-5 &#40;2016&#41;&#44; and EAHFE-6 &#40;2018&#41; registries were analyzed&#44; given that the EAHFE cohorts 1-3 did not gather this information systematically &#40;see Appendix B additional material&#44; in the annex&#44; in which the characteristics of patients in EAHFE 1-3 are compared to those of patients in EAHFE 4-6&#41;&#46; In general&#44; the HH admission criteria include elderly patients with decompensated chronic heart failure &#40;CHF&#41; who are not candidates for interventions or whose CHF is not of coronary origin&#59; have comorbidities&#44; frailty&#44; functional limitation&#44; or are in the palliative and&#47;or terminal phase&#59; are respiratorily and hemodynamically stable upon discharge&#59; and have adequate social support and the possibility for optimal outpatient follow-up&#46; SSU admission criteria include patients with intermediate- or low-risk decompensated CHF with nonsevere triggering factors&#44; who are respiratorily and hemodynamically stable with at least a partial response to immediate treatment&#44; who do not require complex diagnostic or therapeutic procedures&#44; and who are likely to recover in a short period of time &#40;48&#8211;72&#8239;h&#41;&#46; IM admission criteria include elderly patients with decompensated CHF who are not candidates for interventions&#59; whose CHF is not of coronary origin&#59; who have signs of significant comorbidity that could interfere with treatment&#59; who have comorbidities&#44; frailty&#44; functional limitation&#44; or social problems&#59; as well as patients in the terminal phase&#46;<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">9</span></a><span class="elsevierStyleItalic">A priori</span>&#44; the authors interpreted that patients hospitalized in SSU or IM&#8212;though the two groups are not comparable between themselves&#8212;were clear candidates for HH if they met the respiratory and hemodynamic stability criteria&#44; did not require monitoring or the study or treatment of the triggering and&#47;or etiological factor&#44; and had adequate outpatient support&#46; In fact&#44; had there not been HH in these centers&#44; patients in HH would have possibly been admitted to these care areas&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">The independent variables collected included data on demographics&#44; comorbidities&#44; chronic treatment for heart failure&#44; baseline functional condition&#44; severity of the decompensation episode&#44; most frequent triggering factors&#44; treatment administered in the emergency department&#44; and duration of hospitalization&#46; To calculate patients&#8217; risk&#44; three different risk stratification scales were used&#58; the MEESSI-AHF scale&#44;<a class="elsevierStyleCrossRefs" href="#bib0035"><span class="elsevierStyleSup">7&#44;8</span></a> calculated for patients with AHF in the emergency department and which estimates 30-day mortality&#59; the GWTG-HF scale&#44;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">10</span></a> calculated for patients hospitalized due to AHF and which estimates in-hospital mortality&#59; and the EFFECT scale&#44;<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">11</span></a> calculated for patients hospitalized with AHF and which estimates 30-day and 1-year mortality&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">The outcome variables analyzed included all-cause mortality during the first year from the index event and the composite outcome &#40;readmission to the emergency department or hospitalization and death due to any cause&#41; in the 30 days following discharge in patients who survived the episode&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">Qualitative variables are expressed as frequencies and percentages and quantitative variables as means and standard deviation &#40;SD&#41; or as medians and interquartile range &#40;IQR&#41; if they did not follow a normal distribution&#46; Groups were compared using the chi-square test for qualitative variables and the one-way ANOVA test for independent samples for quantitative variables or the Kruskal-Wallis test if they were not normal&#46; Comparisons were made between the group of patients in HH and each of the two independent control groups&#46; The relationship between the place of admission and the different adverse events studied was analyzed by means of a Cox regression model for estimating the proportional risk of patients in HH versus those hospitalized in SSU and IM&#46; The magnitude of the effect was quantified as a hazard ratio &#40;HR&#41; with a 95&#37; confidence interval &#40;95&#37; CI&#41;&#46; The calculation was adjusted for independent variables that were statistically significant among the three groups on the overall comparison&#46; Given that there were missing values for some of them&#44; prior to performing the Cox regression&#44; five new sets of data were created in which the missing values were substituted using the multiple imputation method&#46; Statistical significance was defined as a <span class="elsevierStyleItalic">p</span> value less than &#46;05 or when the 95&#37; CI of the HR excluded the value of 1&#46; The analyses were performed using the SPSS 24 program &#40;IBM&#44; New Castle&#44; NY&#44; USA&#41;&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0075">Results</span><p id="par0040" class="elsevierStylePara elsevierViewall">Six hospitals were identified in which 68 patents were transferred directly from the emergency department to HH &#40;22 from the Clinical Hospital of Barcelona&#44; 13 from the Dr&#46; Peset Hospital of Valencia&#44; 12 from the Marqu&#233;s de Valdecilla Hospital of Santander&#44; 9 from the Terrassa Hospital&#44; and six each from the General Hospital of Alicante and the Infanta Leonor Hospital of Madrid&#41;&#46; During the study period&#44; these hospitals admitted 979 patients in IM and 384 in SSU &#40;the only hospital without an SSU was the Clinical Hospital of Barcelona&#41;&#44; which constituted groups 1 and 2&#44; respectively &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0045" class="elsevierStylePara elsevierViewall">The frequency of HH was 4&#46;7&#37; &#40;95&#37; CI&#8239;&#61;&#8239;3&#46;8&#37; &#8211; 6&#46;0&#37;&#41;&#46; Patients transferred to HH were elderly and had a high degree of comorbidity&#46; Compared to patients admitted to IM&#44; the only difference was that those admitted to HH had a lower left ventricular ejection fraction&#46; Compared to patients admitted to the SSU&#44; HH patients had a lower left ventricular ejection fraction&#44; worse baseline functional class&#44; and received oxygen therapy in the emergency department more frequently&#46; The remaining comparisons showed no significant differences &#40;<a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a>&#41;&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><p id="par0050" class="elsevierStylePara elsevierViewall">Mortality during hospitalization in HH patients was 1&#46;5&#37; &#40;one death&#41;&#44; significantly lower than among those admitted to IM &#40;11&#46;8&#37;&#59; <span class="elsevierStyleItalic">p</span>&#8239;&#61;&#8239;&#46;008&#41; and closer to those hospitalized in SSU &#40;4&#46;7&#37;&#59; <span class="elsevierStyleItalic">p</span>&#8239;&#61;&#8239;&#46;223&#41;&#46; The mean duration of HH was 7&#46;5 days &#40;IQR&#8239;&#61;&#8239;4&#46;5&#8211;12&#41;&#44; similar to what was observed in IM &#40;median&#8239;&#61;&#8239;8&#59; IQR&#8239;&#61;&#8239;5&#8211;13&#59; <span class="elsevierStyleItalic">p</span>&#8239;&#61;&#8239;&#46;106&#41; and greater than what was observed in SSU &#40;median&#8239;&#61;&#8239;4&#59; IQR&#8239;&#61;&#8239;3&#8211;7&#59; <span class="elsevierStyleItalic">p</span>&#8239;&#60;&#8239;&#46;001&#41;&#46; All-cause mortality at one year in patients in HH did not differ with respect to either of the 2 comparator groups after adjusting for variables with an unequal distribution among the 3 groups overall &#40;age&#44; previous AHF episodes&#44; chronic treatment with beta blockers&#44; NYHA functional class&#44; left ventricular ejection fraction&#44; and severity of the episode according to the MEESSI scale&#41;&#46; However&#44; it was observed that readmission to the emergency department during the 30 days following discharge was significantly lower in the HH group&#44; both with respect to the IM &#40;HR&#8239;&#61;&#8239;0&#46;50&#44; 95&#37; CI&#8239;&#61;&#8239;0&#46;25&#8211;0&#46;97&#41; and the SSU groups &#40;HR&#8239;&#61;&#8239;0&#46;37&#59; 95&#37; CI&#8239;&#61;&#8239;0&#46;19&#8211;0&#46;74&#41;&#46; There were no differences in the need for readmission or 30-day mortality following discharge&#46; The pooled event rate at 30 days following discharge was significantly lower compared to the group of patients hospitalized in SSU &#40;HR&#8239;&#61;&#8239;0&#46;52&#44; 95&#37; CI&#8239;&#61;&#8239;0&#46;29&#8211;0&#46;92&#41; &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41;&#46;</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0080">Discussion</span><p id="par0055" class="elsevierStylePara elsevierViewall">The first relevant finding of our study is the small number of centers participating in the registry which transfer patients directly to HH from the emergency department&#46; In addition&#44; among centers who use this healthcare resource&#44; the rate of transfer to HH directly from the emergency department is low&#44; despite the fact that the outcomes achieved in HH are very similar and&#44; in some aspects&#44; even better than those obtained by admitting the patient to the hospital&#46; In this sense&#44; it should be noted that readmission to the emergency department was significantly lower than what was documented in hospitalized patients&#46; Previous observational and quasiexperimental studies have also shown that transferring patients with AHF to HH from the emergency department decreases repeat visits to the emergency department&#46;<a class="elsevierStyleCrossRefs" href="#bib0060"><span class="elsevierStyleSup">12&#44;13</span></a></p><p id="par0060" class="elsevierStylePara elsevierViewall">A period of vulnerability in the first 90&#8211;180 days following a decompensation episode has been described in which patients are more susceptible to adverse outcomes such as repeat visits and&#47;or readmission&#46;<a class="elsevierStyleCrossRef" href="#bib0070"><span class="elsevierStyleSup">14</span></a> It is known that the length of hospital stay&#44;<a class="elsevierStyleCrossRef" href="#bib0075"><span class="elsevierStyleSup">15</span></a> education on self-care&#44;<a class="elsevierStyleCrossRef" href="#bib0080"><span class="elsevierStyleSup">16</span></a> evidence-based treatment optimization and degree of adherence&#44;<a class="elsevierStyleCrossRef" href="#bib0085"><span class="elsevierStyleSup">17</span></a> transition&#44; and close monitoring after discharge are key to short-term outcomes&#46;<a class="elsevierStyleCrossRefs" href="#bib0080"><span class="elsevierStyleSup">16&#8211;18</span></a> In this sense&#44; HH could be a good option for patients with AHF who suffer from a period of decompensation who are hemodynamically stable and who do not need complex diagnostic or therapeutic procedures given that it allows for close monitoring of the process over a prolonged period of time without increasing the risk of adverse events linked to the hospital as well as a progressive titration of medication&#44; education on self-care for the patient and caregiver&#44; and transition of care with the healthcare professionals in charge of the process in the community setting&#46; Therefore&#44; HH must not only be seen as an alternative in competition with conventional hospitalization&#44; and more specifically with SSU&#44; but rather as a unit that allows for an intermediate care transition between the hospital and the community that makes the early discharge of frail patients with AHF who have good social support possible&#46;</p><p id="par0065" class="elsevierStylePara elsevierViewall">The second notable outcome was that patients in HH did not differ in any clinically relevant way from patients admitted to the hospital&#44; although patients admitted to SSU had statistically significant lower risk according to the MEESSI-AHF scale&#44; better functional class&#44; and greater ejection fraction&#46; In this regard&#44; this work does not allow for establishing the clinical reasons behind why the frequency of transfer to HH directly from emergency departments was so low&#46; It is known that one of the main admission criteria for HH is determined by the family situation and social support network&#46;<a class="elsevierStyleCrossRef" href="#bib0095"><span class="elsevierStyleSup">19</span></a> Consequently&#44; the decision to transfer a patient to HH or not could be more related to these circumstances than to purely clinical aspects&#44; such as the patient profile or risk of the episode&#46; In fact&#44; in line with previous studies&#44; this work adds to the body of evidence showing that HH is a safe alternative to conventional hospitalization in terms of mortality&#46;<a class="elsevierStyleCrossRefs" href="#bib0030"><span class="elsevierStyleSup">6&#44;20&#44;21</span></a> On the other hand&#44; it should be noted that unmeasured social support could have an effect on aspects related to self-care and justify the outcomes found in terms of repeat visits&#46; To date&#44; it is known that living alone is associated with worse outcomes&#44;<a class="elsevierStyleCrossRef" href="#bib0110"><span class="elsevierStyleSup">22</span></a> that at-home visits have been demonstrated to reduce readmissions<a class="elsevierStyleCrossRef" href="#bib0090"><span class="elsevierStyleSup">18</span></a> by means of improved recognition of symptoms and adherence to pharmacological treatment and self-care recommendations&#44;<a class="elsevierStyleCrossRefs" href="#bib0090"><span class="elsevierStyleSup">18&#44;23</span></a> and that caregiver education could reduce hospitalizations&#46;<a class="elsevierStyleCrossRef" href="#bib0120"><span class="elsevierStyleSup">24</span></a></p><p id="par0070" class="elsevierStylePara elsevierViewall">This study has important limitations&#46; First&#44; it is an exploratory study carried out on a series of HED selected according to convenience to form part of the EAHFE registry that had patients with AHF transferred directly from the emergency department to HH&#46; Second&#44; the decision to admit patients to HH was made at the discretion of the attending physician in consensus with the patient and caregiver&#44; thus there were no unified criteria among the different centers&#46; Third&#44; there are unmeasured variables in this work that could have had an influence on the outcomes&#44; such as the time spent in the emergency department prior to transfer to HH&#44;<a class="elsevierStyleCrossRef" href="#bib0075"><span class="elsevierStyleSup">15</span></a> the presence and stage of frailty in the patient&#44;<a class="elsevierStyleCrossRefs" href="#bib0125"><span class="elsevierStyleSup">25&#44;26</span></a> the degree of evidence-based treatment optimization and adherence&#44;<a class="elsevierStyleCrossRef" href="#bib0085"><span class="elsevierStyleSup">17</span></a> the education provided and capacity to carry out self-care recommendations&#44;<a class="elsevierStyleCrossRef" href="#bib0135"><span class="elsevierStyleSup">27</span></a> family support and the social support network&#44;<a class="elsevierStyleCrossRef" href="#bib0095"><span class="elsevierStyleSup">19</span></a> the number of visits made during HH&#44; and the type of outpatient follow-up after discharge from HH or the hospital&#46;<a class="elsevierStyleCrossRef" href="#bib0090"><span class="elsevierStyleSup">18</span></a> Lastly&#44; there were results that were not included in the registry that would have been of interest&#44; such as the number of complications during hospitalization&#44; the degree of functional deterioration&#44; or the impact on quality of life&#46;</p><p id="par0075" class="elsevierStylePara elsevierViewall">In conclusion&#44; the transfer of patients with AHF directly to HH from HED is not frequent&#44; despite the fact that it could be as safe an option as hospitalization in general medical departments such as SSU or conventional IM&#46; Future studies are needed to demonstrate whether HH is more or less effective&#44; safe&#44; and cost-effective as a multidimensional program of close&#44; early follow-up in patients with AHF discharged from emergency departments&#46;<a class="elsevierStyleCrossRefs" href="#bib0140"><span class="elsevierStyleSup">28&#44;29</span></a></p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0085">Funding</span><p id="par0080" class="elsevierStylePara elsevierViewall">This study has been possible thanks in part to the PPI15&#47;01019&#44; PI15&#47;00773&#44; PI11&#47;01021&#44; and PI10&#47;01918 grants from the Carlos III Institute of Health from funds from the Ministry of Health&#44; Social Services&#44; and Equality &#40;MSSSI&#44; for its initials in Spanish&#41; and the European Regional Development Fund &#40;ERDF&#41;&#59; grants from the Regional Government of Catalonia for Consolidated Research Groups &#40;GRC 2009&#47;1385 and 2014&#47;0313&#41;&#59; and the La Marat&#243; grant from TV3 &#40;20152510&#41;&#46;</p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0090">Conflicts of interest</span><p id="par0085" class="elsevierStylePara elsevierViewall">The ICA-SEMES group has received unconditioned financial support from Orion-Pharma&#44; Otsuka&#44; and Novartis Espa&#241;a&#46;</p></span></span>"
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        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Objective</span><p id="spar0070" class="elsevierStyleSimplePara elsevierViewall">To describe the frequency&#44; clinical characteristics and outcomes of patients with acute heart failure &#40;AHF&#41; transferred directly from emergency departments to home hospitalisation &#40;HH&#41; and to compare them with those hospitalised in internal medicine &#40;IM&#41; or short-stay units &#40;SSU&#41;&#46;</p></span> <span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Method</span><p id="spar0075" class="elsevierStyleSimplePara elsevierViewall">We included patients with AHF transferred to HH by hospitals that considered this option during the Epidemiology of Acute Heart Failure in Spanish Emergency Departments &#40;EAHFE&#41; 4-5-6 Registries and compared them with patients admitted to IM or SSU in these centres&#46; We compared the adjusted all-cause mortality at 1 year and adverse events 30 days after discharge&#46;</p></span> <span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Results</span><p id="spar0080" class="elsevierStyleSimplePara elsevierViewall">The study included 1473 patients &#40;HH&#47;IM&#47;SSU&#58;68&#47;979&#47;384&#41;&#46; The HH rate was 4&#46;7&#37; &#40;95&#37; CI 3&#46;8&#8211;6&#46;0&#37;&#41;&#46; The patients in HH had few differences compared with those hospitalised in IM and SSUs&#46; The HH mortality was 1&#46;5&#37;&#44; and the HH median stay was 7&#46;5 days &#40;IQR&#44; 4&#46;5&#8211;12&#41;&#44; similar to that of IM &#40;median stay&#44; 8 days&#59; IQR&#44; 5&#8211;13&#59; <span class="elsevierStyleItalic">p</span>&#8239;&#61;&#8239;&#46;106&#41; and longer than that of SSU &#40;median stay&#44; 4 days&#59; IQR&#44; 3&#8211;7&#59; <span class="elsevierStyleItalic">p</span>&#8239;&#60;&#8239;&#46;001&#41;&#46; The all-cause mortality at 1 year for HH did not differ from that of IM &#40;HR&#44; 0&#46;91&#59; 95&#37; CI 0&#46;73&#8211;1&#46;14&#41; or SSU &#40;HR&#44; 0&#46;77&#59; 95&#37; CI 0&#46;46&#8211;1&#46;27&#41;&#59; however&#44; the emergency department readmission rate during the 30 days postdischarge was lower than that of IM &#40;HR&#44; 0&#46;50&#59; 95&#37; CI 0&#46;25&#8211;0&#46;97&#41; and SSU &#40;HR&#44; 0&#46;37&#59; 95&#37; CI 0&#46;19&#8211;0&#46;74&#41;&#46; There were no differences in the need for new hospitalisations or in the 30-day mortality rate&#46;</p></span> <span id="abst0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Conclusions</span><p id="spar0085" class="elsevierStyleSimplePara elsevierViewall">Direct transfer from the emergency department to HH is infrequent despite being a safe option for a certain patient profile with AHF&#46;</p></span>"
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        "resumen" => "<span id="abst0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Objetivo</span><p id="spar0090" class="elsevierStyleSimplePara elsevierViewall">Describir frecuencia&#44; caracter&#237;sticas cl&#237;nicas y evoluci&#243;n de los pacientes con insuficiencia card&#237;aca aguda &#40;ICA&#41; ingresados directamente desde urgencias en hospitalizaci&#243;n a domicilio &#40;HaD&#41; as&#237; como compararlos con los ingresados en medicina interna &#40;MI&#41; o unidad de corta estancia &#40;UCE&#41;&#46;</p></span> <span id="abst0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">M&#233;todo</span><p id="spar0095" class="elsevierStyleSimplePara elsevierViewall">Se incluyeron los pacientes con ICA ingresados en HaD por parte de los hospitales que contemplaban esta opci&#243;n durante los Registros EAHFE 4-5-6 y se compararon con los casos que ingresaron en MI o UCE en estos centros&#46; Se compararon la mortalidad por cualquier causa al a&#241;o y los eventos adversos los 30 d&#237;as tras alta de forma ajustada&#46;</p></span> <span id="abst0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Resultados</span><p id="spar0100" class="elsevierStyleSimplePara elsevierViewall">Se incluyeron 1&#46;473 pacientes &#40;HaD&#47;MI&#47;UCE&#58;68&#47;979&#47;384&#41;&#46; La frecuencia de HaD fue de 4&#44;7&#37; &#40;IC95&#37;&#8239;&#61;&#8239;3&#44;8&#37;&#8211;6&#44;0&#37;&#41;&#46; Los pacientes en HaD tuvieron escasas diferencias respecto a los ingresados en MI y UCE&#46; Su mortalidad durante el ingreso fue de 1&#44;5&#37; y la duraci&#243;n de la estancia mediana fue de 7&#44;5 d&#237;as &#40;RIC&#8239;&#61;&#8239;4&#44;5&#8211;12&#41;&#44; parecida a MI &#40;mediana&#8239;&#61;&#8239;8&#59; RIC&#8239;&#61;&#8239;5&#8211;13&#59; p&#8239;&#61;&#8239;0&#44;106&#41; y superior a UCE &#40;mediana&#8239;&#61;&#8239;4&#59; RIC&#8239;&#61;&#8239;3&#8211;7&#59; p&#8239;&#60;&#8239;0&#44;001&#41;&#46; La mortalidad por cualquier causa al a&#241;o en HaD no difiri&#243; respecto a MI &#40;HR&#8239;&#61;&#8239;0&#44;91&#59; IC95&#37;&#8239;&#61;&#8239;0&#44;73&#8211;1&#44;14&#41; o UCE &#40;HR&#8239;&#61;&#8239;0&#44;77&#59; IC95&#37;&#8239;&#61;&#8239;0&#44;46&#8211;1&#44;27&#41;&#44; pero la reconsulta a urgencias durante los 30 d&#237;as postalta fue menor respecto a MI &#40;HR&#8239;&#61;&#8239;0&#44;50&#59; IC95&#37;&#8239;&#61;&#8239;0&#44;25&#8211;0&#44;97&#41; y a UCE &#40;HR&#8239;&#61;&#8239;0&#44;37&#59; IC95&#37;&#8239;&#61;&#8239;0&#44;19&#8211;0&#44;74&#41;&#46; No hubo diferencias en la necesidad de nuevas hospitalizaciones o en la mortalidad a 30 d&#237;as&#46;</p></span> <span id="abst0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Conclusiones</span><p id="spar0105" class="elsevierStyleSimplePara elsevierViewall">El ingreso directo desde urgencias en HaD es poco frecuente a pesar de ser una opci&#243;n segura en un determinado perfil de pacientes con ICA&#46;</p></span>"
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          2 => array:2 [
            "identificador" => "abst0035"
            "titulo" => "Resultados"
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          3 => array:2 [
            "identificador" => "abst0040"
            "titulo" => "Conclusiones"
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    "NotaPie" => array:3 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0030">Please cite this article as&#58; Mir&#242; &#210;&#44; L&#243;pez D&#237;ez MP&#44; Llorens P&#44; Mir M&#44; L&#243;pez Grima ML&#44; de Alonso H&#44; et al&#46; Frecuencia&#44; perfil y resultados de los pacientes coninsuficiencia cardiaca aguda que ingresandirectamente en hospitalizaci&#243;n a domicilio desdeurgencias&#46; Rev Clin Esp&#46; 2021&#59;221&#58;1&#8211;8&#46;</p>"
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      1 => array:3 [
        "etiqueta" => "1"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Both authors have contributed equally and should be considered first authors&#46;</p>"
        "identificador" => "fn0005"
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        "etiqueta" => "2"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0010">The rest of the Acute Heart Failure - Spanish Society of Emergency Medicine &#40;ICA-SEMES&#44; for its initials in Spanish&#41; group are listed in <a class="elsevierStyleCrossRef" href="#sec0035">Appendix A</a>&#46;</p>"
        "identificador" => "fn0010"
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            "apendice" => "<p id="par0090" class="elsevierStylePara elsevierViewall">Marta Fuentes&#44; Cristina Gil &#40;Hospital Universitario de Salamanca&#41;&#44; H&#233;ctor Alonso&#44; Enrique P&#233;rez-Llantada &#40;Hospital Marqu&#233;s de Valdecilla de Santander&#41;&#44; Francisco Javier Mart&#237;n-S&#225;nchez&#44; Guillermo Llopis Garc&#237;a&#44; Mar Su&#225;rez Cadenas&#44; Beatriz Ang&#243;s&#44; Eduardo Cardassay&#44; Enrique del Toro y Alejandro Puente &#40;Hospital Cl&#237;nico San Carlos de Madrid&#41;&#44; &#210;scar Mir&#243;&#44; V&#237;ctor Gil&#44; Rosa Escoda&#44; Carolina Xipell&#44; Carolina S&#225;nchez &#40;Hospital Cl&#237;nic de Barcelona&#41;&#44; Mar&#237;a Jos&#233; P&#233;rez-Dur&#225;&#44; Eva Salvo &#40;Hospital Polit&#232;cnic La Fe de Valencia&#41;&#44; Jos&#233; Pav&#243;n &#40;Hospital Dr&#46; Negr&#237;n de Las Palmas de Gran Canaria&#41;&#44; Antonio Noval &#40;Hospital Insular de Las Palmas de Gran Canaria&#41;&#44; Jos&#233; Manuel Torres &#40;Hospital Reina Sof&#237;a de C&#243;rdoba&#41;&#44; Mar&#237;a Luisa L&#243;pez-Grima&#44; Amparo Valero&#44; Mar&#237;a &#193;ngeles Juan &#40;Hospital Dr&#46; Peset de Valencia&#41;&#44; Alfons Aguirre&#44; Maria Angels Pedragosa&#44; Silvia M&#237;nguez Mas&#243; &#40;Hospital del Mar de Barcelona&#41;&#44; Mar&#237;a Isabel Alonso&#44; Francisco Ruiz &#40;Hospital de Valme de Sevilla&#41;&#44; Jos&#233; Miguel Franco &#40;Hospital Miguel Servet de Zaragoza&#41;&#44; Ana Bel&#233;n Mecina &#40;Hospital de Alcorc&#243;n de Madrid&#41;&#44; Josep Tost&#44; Marta Berenguer&#44; Ruxandra Donea &#40;Consorci Sanitari de Terrassa&#41;&#44; Susana S&#225;nchez Ram&#243;n&#44; Virginia Carbajosa Rodr&#237;guez &#40;Hospital Universitario R&#237;o Hortega de Valladolid&#41;&#44; Pascual Pi&#241;era&#44; Jos&#233; Andr&#233;s S&#225;nchez Nicol&#225;s &#40;Hospital Reina Sof&#237;a de Murcia&#41;&#44; Raquel Torres Garate &#40;Hospital Severo Ochoa de Madrid&#41;&#44; Aitor Alqu&#233;zar-Arb&#233;&#44; Miguel Alberto Rizzi&#44; Sergio Herrera &#40;Hospital de la Santa Creu i Sant Pau de Barcelona&#41;&#44; Javier Jacob&#44; Alex Roset&#44; Irene Cabello&#44; Antonio Haro &#40;Hospital Universitari de Bellvitge de Barcelona&#41;&#44; Fernando Richard&#44; Jos&#233; Mar&#237;a &#193;lvarez P&#233;rez&#44; Mar&#237;a Pilar L&#243;pez Diez &#40;Hospital Universitario de Burgos&#41;&#44; Pablo Herrero Puente&#44; Joaqu&#237;n V&#225;zquez &#193;lvarez&#44; Bel&#233;n Prieto Garc&#237;a&#44; Mar&#237;a Garc&#237;a Garc&#237;a&#44; Marta S&#225;nchez Gonz&#225;lez &#40;Hospital Universitario Central de Asturias de Oviedo&#41;&#44; Pere Llorens&#44; Patricia Javaloyes&#44; V&#237;ctor Marquina&#44; Inmaculada Jim&#233;nez&#44; N&#233;stor Hern&#225;ndez&#44; Benjam&#237;n Brouzet&#44; Bego&#241;a Espinosa&#44; Adriana Gil &#40;Hospital General de Alicante&#41;&#44; Juan Antonio Andueza &#40;Hospital General Universitario Gregorio Mara&#241;&#243;n de Madrid&#41;&#44; Rodolfo Romero &#40;Hospital Universitario de Getafe de Madrid&#41;&#44; Mart&#237;n Ru&#237;z&#44; Roberto Calvache &#40;Hospital de Henares de Madrid&#41;&#44; Mar&#237;a Teresa Lorca Serralta&#44; Luis Ernesto Calder&#243;n Jave &#40;Hospital del Tajo de Madrid&#41;&#44; Beatriz Amores Arriaga&#44; Beatriz Sierra Bergua &#40;Hospital Cl&#237;nico Lozano Blesa de Zaragoza&#41;&#44; Enrique Mart&#237;n Mojarro&#44; Brigitte Silvana Alarc&#243;n Jim&#233;nez &#40;Hospital Sant Pau i Santa Tecla de Tarragona&#41;&#44; Lisette Traver&#237;a B&#233;cquer&#44; Guillermo Burillo &#40;Hospital Universitario de Canarias de Tenerife&#41;&#44; Llu&#237;s Llauger Garc&#237;a&#44; Gerard Corominas LaSalle&#46; &#40;Hospital Universitari de Vic de Barcelona&#41;&#44; Carmen Ag&#252;era Urbano&#44; Ana Bel&#233;n Garc&#237;a Soto&#44; Elisa Delgado Padial &#40;Hospital Costa del Sol de Marbella de M&#225;laga&#41;&#44; Ester Soy Ferrer&#44; Mar&#237;a Adroher Mu&#241;oz &#40;Hospital Josep Trueta de Girona&#41;&#46; Jos&#233; Manuel Garrido &#40;Hospital Virgen Macarena de Sevilla&#41;&#44; Francisco Javier Lucas-Imbern&#243;n &#40;Hospital General Universitario de Albacete&#41;&#44; Rut Gaya &#40;Hospital Juan XXIII de Tarragona&#41;&#44; Carlos Bibiano&#44; Mar&#237;a Mir&#44; Beatriz Rodr&#237;guez &#40;Hospital Infanta Leonor de Madrid&#41;&#44; Jos&#233; Luis Carballo &#40;Complejo Hospitalario Universitario de Ourense&#41;&#44; Esther Rodr&#237;guez-Adrada&#44; Bel&#233;n Rodr&#237;guez Miranda&#44; Monika Vicente Mart&#237;n &#40;Hospital Rey Juan Carlos de M&#243;stoles de Madrid&#41;&#44; Pere Coma Casanova&#44; Joan Espinach Alvar&#243;s &#40;Hospital San Joan de D&#233;u de Martorell&#44; Barcelona&#41;&#46;</p>"
            "etiqueta" => "Appendix A"
            "titulo" => "Remaining members of the ICA-SEMES group"
            "identificador" => "sec0035"
          ]
          1 => array:4 [
            "apendice" => "<p id="par0100" class="elsevierStylePara elsevierViewall">The following is Supplementary data to this article&#58;<elsevierMultimedia ident="upi0005"></elsevierMultimedia></p>"
            "etiqueta" => "Appendix B"
            "titulo" => "Supplementary data"
            "identificador" => "sec0045"
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          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Patient inclusion flowchart&#46;</p>"
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        "etiqueta" => "Fig&#46; 2"
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          "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Proportional risk curves for all-cause mortality at one year &#40;top&#41; and adverse events during the month following hospital discharge for patients admitted to home hospitalization&#44; internal medicine wards&#44; and short-stay units&#46; The hazard ratios correspond to estimates for the home hospitalization group with respect to the other two groups adjusted for differences &#40;age&#44; prior episodes of acute heart failure&#44; chronic treatment with beta blockers&#44; NYHA functional class&#44; left ventricular ejection fraction&#44; and episode severity stratification according to the MEESSI scale&#41;&#46;</p>"
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          "leyenda" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Abbreviations&#58; SD&#58; standard deviation&#59; LVEF&#58; left ventricular ejection fraction&#59; HH&#58; home hospitalization&#59; IM&#58; Internal Medicine&#59; SSU&#58; short-stay unit&#46;</p><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleSup">a</span><span class="elsevierStyleItalic">p</span>&#8239;&#60;&#8239;&#46;05 for the comparison of patients admitted directly to home hospitalization with respect to group 2 &#40;short-stay unit&#41;&#46;</p><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleSup">b</span><span class="elsevierStyleItalic">p</span>&#8239;&#60;&#8239;&#46;05 for the comparison of patients admitted directly to home hospitalization with respect to group 1 &#40;Internal Medicine&#41;&#46;</p><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">The <span class="elsevierStyleItalic">p</span> values in bold indicate those that are statistically significant &#40;<span class="elsevierStyleItalic">p</span>&#8239;&#60;&#8239;&#46;05&#41;&#46;</p><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleSup">1</span>61 patients &#40;4&#46;3&#37;&#41; with missing values&#46;</p><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleSup">2</span>73 patients &#40;5&#46;1&#37;&#41; with missing values&#46;</p><p id="spar0050" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleSup">3</span>610 patients &#40;42&#46;6&#37;&#41; with missing values&#46;</p><p id="spar0055" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleSup">4</span>455 patients &#40;31&#46;8&#37;&#41; with missing values&#46;</p><p id="spar0060" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleSup">5</span>312 patients &#40;21&#46;8&#37;&#41; with missing values&#46;</p><p id="spar0065" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleSup">6</span>543 patients &#40;37&#46;9&#37;&#41; with missing values&#46;</p>"
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                  \t\t\t\t">&#46;146&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">55 &#40;80&#46;9&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Diabetes mellitus&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">23 &#40;33&#46;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">433 &#40;44&#46;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">165 &#40;43&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#46;242&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Ischemic cardiopathy&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">19 &#40;27&#46;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">226 &#40;23&#46;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">99 &#40;25&#46;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#46;429&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Chronic kidney disease &#40;creatinine &#62; 2&#8239;mg&#47;dL&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">27 &#40;39&#46;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">304 &#40;31&#46;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">112 &#40;29&#46;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#46;221&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Cerebrovascular disease&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">7 &#40;10&#46;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">107 &#40;10&#46;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">47 &#40;12&#46;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#46;764&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Atrial fibrillation&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">30 &#40;40&#46;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">450 &#40;46&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">197 &#40;51&#46;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#46;179&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Valvular heart disease&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">15 &#40;22&#46;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">198 &#40;20&#46;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">76 &#40;19&#46;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#46;911&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Peripheral artery disease&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">7 &#40;10&#46;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">69 &#40;7&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">27 &#40;7&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#46;599&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Chronic obstructive pulmonary disease&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">21 &#40;30&#46;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">270 &#40;27&#46;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">89 &#40;23&#46;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#46;180&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Previous episodes of acute heart failure&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">51 &#40;75&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">679 &#40;69&#46;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">291 &#40;75&#46;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">&#46;049</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " colspan="5" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">Chronic at-home treatment</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Beta blockers&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">35 &#40;51&#46;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">401 &#40;41&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">188 &#40;49&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">&#46;011</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Renin-angiotensin-aldosterone system inhibitors&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">38 &#40;55&#46;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">494 &#40;50&#46;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">208 &#40;54&#46;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#46;365&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Mineralocorticoid receptor antagonist&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">8 &#40;8&#46;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">129 &#40;13&#46;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">64 &#40;16&#46;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#46;114&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Digoxin&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">6 &#40;8&#46;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">107 &#40;10&#46;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">30 &#40;7&#46;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#46;214&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " colspan="5" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">Baseline condition</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>NYHA class III&#47;IV<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">23 &#40;34&#46;8&#41;<span class="elsevierStyleSup">a</span>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">309 &#40;33&#46;1&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">78 &#40;21&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t"><span class="elsevierStyleBold">&#60;&#46;001</span>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Barthel index &#40;points&#41; &#91;mean &#40;SD&#41;&#93;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">70 &#40;28&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">73 &#40;26&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">75 &#40;26&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">&#46;417&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>LVEF &#40;&#37;&#41;&#91;mean &#40;SD&#41;&#93;<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">48 &#40;14&#41;<span class="elsevierStyleSup">a&#44;b</span>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">56 &#40;13&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t"><span class="elsevierStyleBold">&#46;001</span>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t ; entry_with_role_rowhead " colspan="5" align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleBold">Most frequent triggering factors</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
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                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Infection&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">32 &#40;47&#46;1&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">436 &#40;47&#46;2&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">166 &#40;44&#46;4&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">&#46;644&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Hypertensive episode&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">6 &#40;8&#46;8&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">58 &#40;6&#46;3&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">24 &#40;6&#46;4&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">&#46;710&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Anemia&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">3 &#40;4&#46;4&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">65 &#40;7&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">30 &#40;8&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">&#46;545&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Atrial fibrillation with rapid ventricular response&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t">6 &#40;8&#46;8&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">119 &#40;2&#46;9&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">50 &#40;13&#46;4&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">&#46;584&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Medication noncompliance&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">1 &#40;1&#46;5&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">41 &#40;4&#46;4&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">6 &#40;4&#46;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">&#46;504&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
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                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Acute coronary syndrome&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">0 &#40;0&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">19 &#40;2&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">5 &#40;1&#46;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">&#46;374&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
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                  \t\t\t\t ; entry_with_role_rowhead " colspan="5" align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleBold">Emergency department treatment</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Oxygen therapy&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">58 &#40;86&#46;6&#41;<span class="elsevierStyleSup">a</span>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">815 &#40;84&#46;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t">283 &#40;74&#46;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t"><span class="elsevierStyleBold">&#60; &#46;001</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Noninvasive ventilation&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">7 &#40;10&#46;4&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t">105 &#40;10&#46;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t">32 &#40;8&#46;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">&#46;399&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Intravenous loop diuretics in boli&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">64 &#40;95&#46;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t">883 &#40;91&#46;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t">336 &#40;88&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">&#46;066&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Intravenous loop diuretics in perfusion&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3 &#40;4&#46;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">9 &#40;0&#46;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t">2 &#40;0&#46;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t"><span class="elsevierStyleBold">&#46;010</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Intravenous nitroglycerin&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4 &#40;6&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">82 &#40;8&#46;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">31 &#40;8&#46;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#46;767&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " colspan="5" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">Severity of the decompensation episode</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>MEESSI scale &#40;30-day mortality in the emergency department&#41;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleBold">&#46;036</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleHsp" style=""></span>Low risk&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">13 &#40;31&#46;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">172 &#40;27&#46;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">108 &#40;36&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleHsp" style=""></span>Intermediate risk&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">20 &#40;48&#46;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">304 &#40;47&#46;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">138 &#40;46&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleHsp" style=""></span>High&#47;very high risk&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">8 &#40;19&#46;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">159 &#40;25&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">54 &#40;18&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>GWTG Scale &#40;in-hospital mortality in hospitalized patients&#41;<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#46;460&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleHsp" style=""></span>Low risk &#40;&#60;5&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2 &#40;5&#46;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">44 &#40;6&#46;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">25 &#40;6&#46;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleHsp" style=""></span>Intermediate risk &#40;5&#8211;10&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">26 &#40;68&#46;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">414 &#40;57&#46;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">223 &#40;61&#46;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleHsp" style=""></span>Very high risk &#40;&#62;10&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">10 &#40;26&#46;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">260 &#40;36&#46;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">115 &#40;31&#46;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>EFFECT scale &#40;30-day mortality in hospitalized patients&#41;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#46;570&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleHsp" style=""></span>Very low&#47;low risk&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4 &#40;13&#46;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">51 &#40;9&#46;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">25 &#40;7&#46;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleHsp" style=""></span>Intermediate risk&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">13 &#40;44&#46;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">197 &#40;37&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">127 &#40;39&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleHsp" style=""></span>High&#47;very high risk&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">12 &#40;41&#46;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">285 &#40;53&#46;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">174 &#40;53&#46;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
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          "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Comparison of patient characteristics based on different hospitalization units&#46;</p>"
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      "titulo" => "References"
      "seccion" => array:1 [
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          "identificador" => "bibs0005"
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                  "referenciaCompleta" => "Ministerio de Sanidad&#44; Servicios Sociales e Igualdad&#46; Principales indicadores de los 20 GRD m&#225;s frecuentes&#46; Access&#58; 23-11-2015&#46; Avaliable in&#58; http&#58;&#47;&#47;www&#46;msssi&#46;gob&#46;es&#47;estadEstudios&#47;&#46; estadisticas&#47;cmbd&#47;informes&#47;2008&#95;2011&#47;7&#95;Principales&#95;indicadores&#95;de&#95;los&#95;20&#95;GRD&#95;mas&#95;frecuentes&#47;7&#95;Principales&#95;indicadores&#95;de&#95;los&#95;20&#95;GRD&#95;mas&#95;frecuentes&#46;html&#46;"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Forecasting the impact of heart failure in the United States&#58; a policy statement from the American Heart Association"
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                          "etal" => true
                          "autores" => array:6 [
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                            1 => "N&#46;M&#46; Albert"
                            2 => "L&#46;A&#46; Allen"
                            3 => "D&#46;A&#46; Bluemke"
                            4 => "J&#46; Butler"
                            5 => "G&#46;C&#46; Fonarow"
                          ]
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                    0 => array:2 [
                      "doi" => "10.1161/HHF.0b013e318291329a"
                      "Revista" => array:6 [
                        "tituloSerie" => "Circ Heart Fail"
                        "fecha" => "2013"
                        "volumen" => "6"
                        "paginaInicial" => "606"
                        "paginaFinal" => "619"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23616602"
                            "web" => "Medline"
                          ]
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              "identificador" => "bib0015"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Economic impact of heart failure according to the effects of kidney failure"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:2 [
                            0 => "A&#46; Sicras Mainar"
                            1 => "R&#46; Navarro Artieda"
                          ]
                        ]
                      ]
                    ]
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                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.rec.2014.02.021"
                      "Revista" => array:6 [
                        "tituloSerie" => "Rev Esp Cardiol"
                        "fecha" => "2015"
                        "volumen" => "68"
                        "paginaInicial" => "39"
                        "paginaFinal" => "46"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25553938"
                            "web" => "Medline"
                          ]
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                      ]
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                  ]
                ]
              ]
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              "identificador" => "bib0020"
              "etiqueta" => "4"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Survival after the onset of congestive heart failure in Framingham heart study subjects"
                      "autores" => array:1 [
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                          "etal" => false
                          "autores" => array:5 [
                            0 => "K&#46;K&#46;L&#46; Ho"
                            1 => "K&#46;M&#46; Anderson"
                            2 => "W&#46;B&#46; Kannel"
                            3 => "W&#46; Grosssman"
                            4 => "D&#46; Levy"
                          ]
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                        "tituloSerie" => "Circulation"
                        "fecha" => "1993"
                        "volumen" => "88"
                        "paginaInicial" => "107"
                        "paginaFinal" => "115"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8319323"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
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              "identificador" => "bib0025"
              "etiqueta" => "5"
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                0 => array:2 [
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                    0 => array:2 [
                      "titulo" => "Time trends in characteristics&#44; clinical course&#44; and outcomes of 13&#44;791 patients with acute heart failure"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
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                            1 => "P&#46; Javaloyes"
                            2 => "F&#46;J&#46; Mart&#237;n-S&#225;nchez"
                            3 => "J&#46; Jacob"
                            4 => "P&#46; Herrero-Puente"
                            5 => "V&#46; Gil"
                          ]
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                    ]
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                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s00392-018-1261-z"
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Res Cardiol"
                        "fecha" => "2018"
                        "volumen" => "107"
                        "paginaInicial" => "897"
                        "paginaFinal" => "913"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/29728831"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
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              "identificador" => "bib0030"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Efficacy of Hospital at Home in Patients with Heart Failure&#58; A Systematic Review and Meta-Analysis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "A&#46; Qaddoura"
                            1 => "P&#46; Yazdan-Ashoori"
                            2 => "C&#46; Kabali"
                            3 => "L&#46; Thabane"
                            4 => "R&#46;B&#46; Haynes"
                            5 => "S&#46;J&#46; Connolly"
                          ]
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                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1371/journal.pone.0141892"
                      "Revista" => array:5 [
                        "tituloSerie" => "PLoS One"
                        "fecha" => "2015"
                        "volumen" => "10"
                        "numero" => "6"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26720074"
                            "web" => "Medline"
                          ]
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                ]
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              "identificador" => "bib0035"
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                0 => array:2 [
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                    0 => array:2 [
                      "titulo" => "Predicting 30-Day Mortality for Patients With Acute Heart Failure in the Emergency Department&#58; A Cohort Study"
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                            2 => "V&#46; Gil"
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                            4 => "P&#46; Llorens"
                            5 => "P&#46; Herrero-Puente"
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                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.7326/M16-2726"
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                        "tituloSerie" => "Ann Intern Med"
                        "fecha" => "2017"
                        "volumen" => "167"
                        "paginaInicial" => "698"
                        "paginaFinal" => "705"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/28973663"
                            "web" => "Medline"
                          ]
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                0 => array:2 [
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                    0 => array:2 [
                      "titulo" => "Eventos adversos en pacientes con insuficiencia cardiaca aguda clasificados de bajo riesgo por la escala MEESSI y dados de alta desde urgencias&#58; cuantificaci&#243;n y predictibilidad"
                      "autores" => array:1 [
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                            5 => "J&#46; Jacob"
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                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Emergencias"
                        "fecha" => "2019"
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                        "paginaInicial" => "5"
                        "paginaFinal" => "14"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/30656867"
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                    0 => array:2 [
                      "titulo" => "Consenso para la mejora de la atenci&#243;n integral a los pacientes con insuficiencia cardiaca aguda"
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                            5 => "E&#46;D&#46; Peterson"
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                        "paginaFinal" => "266"
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                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/29087082"
                            "web" => "Medline"
                          ]
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                0 => array:2 [
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                    0 => array:2 [
                      "titulo" => "A validated risk score for in-hospital mortality in patients with heart failure from the American Heart Association get with the guidelines program"
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                          "etal" => true
                          "autores" => array:6 [
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                            4 => "A&#46;F&#46; Hernandez"
                            5 => "E&#46;D&#46; Peterson"
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                        "tituloSerie" => "Circ Cardiovasc Qual Outcomes"
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                        "paginaFinal" => "32"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20123668"
                            "web" => "Medline"
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                      "titulo" => "Predicting mortality among patients hospitalized for heart failure derivation and validation of a clinical model"
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                          "etal" => false
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                        "tituloSerie" => "JAMA"
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                        "volumen" => "290"
                        "paginaInicial" => "2581"
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                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14625335"
                            "web" => "Medline"
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                    0 => array:2 [
                      "titulo" => "Effect of home hospitalization in the reduction of traditional hospitalization and frequency of emergencies in heart failure"
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                          "etal" => true
                          "autores" => array:4 [
                            0 => "S&#46; Bechich"
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                        "tituloSerie" => "Rev Clin Esp"
                        "fecha" => "2000"
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                        "paginaInicial" => "310"
                        "paginaFinal" => "314"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10953583"
                            "web" => "Medline"
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                0 => array:2 [
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                    0 => array:2 [
                      "titulo" => "Treatment of congestive heart failure in the setting of hospital at home&#46; Study of 158 patients"
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                        0 => array:2 [
                          "etal" => true
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                            0 => "H&#46; Mendoza Ruiz de Zuazu"
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                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Med Clin &#40;Barc&#41;"
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                        "numero" => "11"
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                        "paginaFinal" => "407"
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                    0 => array:2 [
                      "titulo" => "Post-hospital syndrome&#8211;an acquired&#44; transient condition of generalized risk"
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                          "etal" => false
                          "autores" => array:1 [
                            0 => "H&#46;M&#46; Krumholz"
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                        "tituloSerie" => "N Engl J Med&#46;"
                        "fecha" => "2013"
                        "volumen" => "368"
                        "paginaInicial" => "100"
                        "paginaFinal" => "102"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23301730"
                            "web" => "Medline"
                          ]
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                      ]
                    ]
                  ]
                ]
              ]
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              "identificador" => "bib0075"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Associations Between Short or Long Length of Stay and 30-Day Readmission and Mortality in Hospitalized Patients With Heart Failure"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
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                            4 => "D&#46;T&#46; Ko"
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                    0 => array:2 [
                      "doi" => "10.1016/j.jchf.2017.03.012"
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                        "tituloSerie" => "JACC Heart Fail"
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                        "numero" => "8"
                        "paginaInicial" => "578"
                        "paginaFinal" => "588"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/28501521"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
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              "identificador" => "bib0080"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Effectiveness and Factors Determining the Success of Management Programs for Patients With Heart Failure&#58; A Systematic Review and Meta-analysis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
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                            1 => "P&#46;M&#46; Latorre Garc&#237;a"
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                            3 => "GoyaI Lekuona"
                            4 => "S&#46; Rubio Mart&#237;n"
                            5 => "E&#46; Maull Lafuente"
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                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Rev Esp Cardiol &#40;Engl Ed&#41;"
                        "fecha" => "2016"
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                        "numero" => "10"
                        "paginaInicial" => "900"
                        "paginaFinal" => "914"
                      ]
                    ]
                  ]
                ]
              ]
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              "identificador" => "bib0085"
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              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure&#58; The Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology &#40;ESC&#41;Developed with the special contribution of the Heart Failure Association &#40;HFA&#41; of the ESC"
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                        0 => array:2 [
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                            0 => "P&#46; Ponikowski"
                            1 => "A&#46;A&#46; Voors"
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                            3 => "H&#46; Bueno"
                            4 => "J&#46;G&#46;F&#46; Cleland"
                            5 => "A&#46;J&#46;S&#46; Coats"
                          ]
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                      ]
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                    0 => array:2 [
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                        "tituloSerie" => "Eur Heart J"
                        "fecha" => "2016"
                        "volumen" => "37"
                        "numero" => "27"
                        "paginaInicial" => "2129"
                        "paginaFinal" => "2200"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/27206819"
                            "web" => "Medline"
                          ]
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                      ]
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                  ]
                ]
              ]
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Transitional care interventions to prevent readmissions for persons with heart failure&#58; a systematic review and meta-analysis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
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                            1 => "C&#46;D&#46; Jones"
                            2 => "C&#46;W&#46; Cen&#233;"
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                            4 => "C&#46;A&#46; Sueta"
                            5 => "E&#46;J&#46; Coker-Schwimmer"
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                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.7326/M14-0083"
                      "Revista" => array:7 [
                        "tituloSerie" => "Ann Intern Med"
                        "fecha" => "2014"
                        "volumen" => "160"
                        "numero" => "11"
                        "paginaInicial" => "774"
                        "paginaFinal" => "784"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24862840"
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                    0 => array:2 [
                      "titulo" => "Los factores psicosociales determinan la aceptaci&#243;n de la hospitalizaci&#243;n a domicilio directamente desde el servicio de urgencias"
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                        0 => array:2 [
                          "etal" => true
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                            2 => "V&#46; Gil"
                            3 => "A&#46; Antol&#237;n"
                            4 => "S&#46; Prieto"
                            5 => "E&#46; Bragulat"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.gaceta.2010.03.012"
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                        "tituloSerie" => "Gac Sanit"
                        "fecha" => "2010"
                        "volumen" => "24"
                        "numero" => "4"
                        "paginaInicial" => "303"
                        "paginaFinal" => "308"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20663592"
                            "web" => "Medline"
                          ]
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                      ]
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                ]
              ]
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                    0 => array:2 [
                      "titulo" => "&#8217;Hospital at home&#8217; care model as an effective alternative in the management of decompensated chronic heart failure"
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                            1 => "M&#46;J&#46; Mart&#237;n"
                            2 => "A&#46; Garc&#237;a"
                            3 => "F&#46; Ar&#243;s"
                            4 => "F&#46; Aizpuru"
                            5 => "J&#46; Regalado delos Cobos"
                          ]
                        ]
                      ]
                    ]
                  ]
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                    0 => array:2 [
                      "doi" => "10.1093/eurjhf/hfp143"
                      "Revista" => array:7 [
                        "tituloSerie" => "Eur J Heart Fail"
                        "fecha" => "2009"
                        "volumen" => "11"
                        "numero" => "12"
                        "paginaInicial" => "1208"
                        "paginaFinal" => "1213"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19875400"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
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              "identificador" => "bib0105"
              "etiqueta" => "21"
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                0 => array:2 [
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                    0 => array:2 [
                      "titulo" => "Hospital at home for elderly patients with acute decompensation of chronic heart failure&#58; a prospective randomized controlled trial"
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                          "etal" => true
                          "autores" => array:6 [
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                            1 => "G&#46; Isaia"
                            2 => "C&#46; Scarafiotti"
                            3 => "F&#46; Gariglio"
                            4 => "M&#46; Zanocchi"
                            5 => "M&#46; Bo"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1001/archinternmed.2009.267"
                      "Revista" => array:7 [
                        "tituloSerie" => "Arch Intern Med"
                        "fecha" => "2009"
                        "volumen" => "169"
                        "numero" => "17"
                        "paginaInicial" => "1569"
                        "paginaFinal" => "1575"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19786675"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
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              "identificador" => "bib0110"
              "etiqueta" => "22"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Initiation of domiciliary care and nursing home admission following first hospitalization of heart failure patients&#58; a nationwide cohort study"
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                          "etal" => true
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                            3 => "U&#46;M&#46; Mogensen"
                            4 => "P&#46;S&#46; Jhund"
                            5 => "M&#46;C&#46; Petrie"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.2147/CLEP.S164795"
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Epidemiol"
                        "fecha" => "2018"
                        "volumen" => "10"
                        "paginaInicial" => "917"
                        "paginaFinal" => "930"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/30123004"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
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                0 => array:2 [
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                    0 => array:2 [
                      "titulo" => "Home Healthcare Visits Following Hospital Discharge&#58; Does the Timing of Visits Affect 30-Day Hospital Readmission Rates for Heart Failure Patients&#63;"
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                        0 => array:2 [
                          "etal" => true
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                            1 => "A&#46; Briggs"
                            2 => "N&#46; Powell"
                            3 => "J&#46; Brockman"
                            4 => "J&#46; Taylor"
                            5 => "A&#46; Butler"
                          ]
                        ]
                      ]
                    ]
                  ]
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                    0 => array:2 [
                      "doi" => "10.1097/NHH.0000000000000740"
                      "Revista" => array:7 [
                        "tituloSerie" => "Home Healthc Now"
                        "fecha" => "2019"
                        "volumen" => "37"
                        "numero" => "3"
                        "paginaInicial" => "152"
                        "paginaFinal" => "157"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/31058733"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
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                      "titulo" => "Home care for heart failure&#58; can caregiver education prevent hospital admissions&#63; A randomized trial in primary care"
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                          ]
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                      ]
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                        "numero" => "1"
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                        "paginaFinal" => "38"
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                      "titulo" => "Impacto de las variables geri&#225;tricas en la mortalidad a 30 d&#237;as de los ancianos atendidos por insuficiencia cardiaca aguda"
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                            1 => "E&#46; Rodr&#237;guez-Adrada"
                            2 => "M&#46;T&#46; Vidan"
                            3 => "P&#46; D&#237;ez Villanueva"
                            4 => "G&#46; Llopis Garc&#237;a"
                            5 => "J&#46; Gonz&#225;lez del Castillo"
                          ]
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                      ]
                    ]
                  ]
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                      "Revista" => array:6 [
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                        "paginaFinal" => "155"
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                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/29687668"
                            "web" => "Medline"
                          ]
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                      ]
                    ]
                  ]
                ]
              ]
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                    0 => array:2 [
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                            2 => "M&#46;A&#46; Garc&#237;a Bri&#732;n&#243;n"
                            3 => "C&#46; Fern&#225;n-dez Alonso"
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                          ]
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                    ]
                  ]
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                        "paginaFinal" => "416"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/31777214"
                            "web" => "Medline"
                          ]
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                      ]
                    ]
                  ]
                ]
              ]
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                    0 => array:2 [
                      "titulo" => "Most elderly patients hospitalized for heart failure lack the abilities needed to perform the tasks required for self-care&#58; impact on outcomes"
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                            2 => "E&#46; S&#225;nchez"
                            3 => "F&#46;J&#46; Ortiz"
                            4 => "J&#46;A&#46; Serra-Rexach"
                            5 => "M&#46; Mart&#237;nez-Sell&#233;s"
                          ]
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                      "Revista" => array:7 [
                        "tituloSerie" => "Eur J Heart Fail"
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                        "numero" => "11"
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                        "paginaFinal" => "1442"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/31373161"
                            "web" => "Medline"
                          ]
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                      ]
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                  ]
                ]
              ]
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