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Fernández-Bermejo, G. Ramírez-Olivencia" "autores" => array:2 [ 0 => array:4 [ "nombre" => "L.A." "apellidos" => "Fernández-Bermejo" "email" => array:1 [ 0 => "larafernandezber@gmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "*" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "G." "apellidos" => "Ramírez-Olivencia" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio de Medicina Interna, Hospital de la Fuenfría, Cercedilla, Madrid, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicio de Medicina Interna, Hospital Central de la Defensa, Madrid, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "pt" => array:1 [ "titulo" => "Aspergilosis pulmonar invasiva" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0015" "etiqueta" => "Figure 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 680 "Ancho" => 905 "Tamanyo" => 236478 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0015" "detalle" => "Figure " "rol" => "short" ] ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">We present the case of a 76-year-old man with a personal history of prostate adenocarcinoma diagnosed in 2006, which progressed with bone and lymph node metastasis. The patient was admitted for lower back pain. The hemogram revealed lymphopenia, while the other parameters were within normal limits. Dorsal magnetic resonance imaging revealed metastases at the T3 and T4 level, with no signs of spinal compression. The patient therefore underwent palliative analgesic radiation therapy and treatment with dexamethasone. Due to worsening symptoms, the patient underwent thorax-abdomen-pelvic computed tomography (CT-TAP) due to suspected tumor progression, which showed multiple pulmonary nodules, most of which were cavitary (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>).</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">Positron emission tomography/CT showed uptake in the pulmonary nodules in the right lung (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>). Given the patient’s tumor history with cell immunosuppression and corticosteroid treatment, we requested various microbiological tests. The <span class="elsevierStyleItalic">Aspergillus spp</span> culture from bronchoaspirate and cerebrospinal fluid was negative.</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">We performed fibrobronchoscopy with transbronchial biopsy of the middle lobe, which showed the presence of septate hyphae with acute angle branching consistent with the tested pulmonary aspergillosis (<a class="elsevierStyleCrossRef" href="#fig0015">Fig. 3</a>).</p><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0020" class="elsevierStylePara elsevierViewall">The isolation of <span class="elsevierStyleItalic">Aspergillus spp</span> in culture does not indicate disease, and its absence in culture does not rule out disease; however, the demonstration of tissue-invading hyphae in a biopsy represents a proven diagnosis.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2019-02-25" "fechaAceptado" => "2019-03-09" "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Fernández-Bermejo LA, Ramírez-Olivencia G. Aspergilosis pulmonar invasiva. Rev Clin Esp. 2020;220:522–523.</p>" ] ] "multimedia" => array:3 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 518 "Ancho" => 905 "Tamanyo" => 51264 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0005" "detalle" => "Figure " "rol" => "short" ] ] ] 1 => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 1504 "Ancho" => 1510 "Tamanyo" => 153492 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0010" "detalle" => "Figure " "rol" => "short" ] ] ] 2 => array:7 [ "identificador" => "fig0015" "etiqueta" => "Figure 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 680 "Ancho" => 905 "Tamanyo" => 236478 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0015" "detalle" => "Figure " "rol" => "short" ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/22548874/0000022000000008/v2_202102250825/S2254887419302012/v2_202102250825/en/main.assets" "Apartado" => array:4 [ "identificador" => "71811" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Medicine in images" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/22548874/0000022000000008/v2_202102250825/S2254887419302012/v2_202102250825/en/main.pdf?idApp=WRCEE&text.app=https://revclinesp.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2254887419302012?idApp=WRCEE" ]
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