array:24 [
  "pii" => "S2254887419300463"
  "issn" => "22548874"
  "doi" => "10.1016/j.rceng.2019.03.001"
  "estado" => "S300"
  "fechaPublicacion" => "2020-03-01"
  "aid" => "1615"
  "copyright" => "Elsevier España, S.L.U. and Sociedad Española de Medicina Interna (SEMI)"
  "copyrightAnyo" => "2019"
  "documento" => "article"
  "crossmark" => 1
  "subdocumento" => "sco"
  "cita" => "Rev Clin Esp. 2020;220:143"
  "abierto" => array:3 [
    "ES" => false
    "ES2" => false
    "LATM" => false
  ]
  "gratuito" => false
  "lecturas" => array:1 [
    "total" => 0
  ]
  "Traduccion" => array:1 [
    "es" => array:19 [
      "pii" => "S0014256519300128"
      "issn" => "00142565"
      "doi" => "10.1016/j.rce.2018.11.009"
      "estado" => "S300"
      "fechaPublicacion" => "2020-03-01"
      "aid" => "1615"
      "copyright" => "Elsevier España, S.L.U. and Sociedad Española de Medicina Interna (SEMI)"
      "documento" => "article"
      "crossmark" => 1
      "subdocumento" => "sco"
      "cita" => "Rev Clin Esp. 2020;220:143"
      "abierto" => array:3 [
        "ES" => false
        "ES2" => false
        "LATM" => false
      ]
      "gratuito" => false
      "lecturas" => array:2 [
        "total" => 16
        "formatos" => array:2 [
          "HTML" => 8
          "PDF" => 8
        ]
      ]
      "es" => array:11 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Medicina en im&#225;genes</span>"
        "titulo" => "Enfermedad de Fahr"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "paginas" => array:1 [
          0 => array:1 [
            "paginaInicial" => "143"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Fahr&#39;s disease"
          ]
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "resumenGrafico" => array:2 [
          "original" => 0
          "multimedia" => array:6 [
            "identificador" => "fig0010"
            "etiqueta" => "Figura 1"
            "tipo" => "MULTIMEDIAFIGURA"
            "mostrarFloat" => true
            "mostrarDisplay" => false
            "figura" => array:1 [
              0 => array:4 [
                "imagen" => "gr1.jpeg"
                "Alto" => 829
                "Ancho" => 900
                "Tamanyo" => 53070
              ]
            ]
          ]
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "J&#46;M&#46; Mart&#237;n Guerra, M&#46; Mart&#237;n Asenjo, J&#46;M&#46; Prieto de Paula"
            "autores" => array:3 [
              0 => array:2 [
                "nombre" => "J&#46;M&#46;"
                "apellidos" => "Mart&#237;n Guerra"
              ]
              1 => array:2 [
                "nombre" => "M&#46;"
                "apellidos" => "Mart&#237;n Asenjo"
              ]
              2 => array:2 [
                "nombre" => "J&#46;M&#46;"
                "apellidos" => "Prieto de Paula"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S2254887419300463"
          "doi" => "10.1016/j.rceng.2019.03.001"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => false
            "ES2" => false
            "LATM" => false
          ]
          "gratuito" => false
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2254887419300463?idApp=WRCEE"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0014256519300128?idApp=WRCEE"
      "url" => "/00142565/0000022000000002/v1_202002140803/S0014256519300128/v1_202002140803/es/main.assets"
    ]
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S2254887419302358"
    "issn" => "22548874"
    "doi" => "10.1016/j.rceng.2019.09.006"
    "estado" => "S300"
    "fechaPublicacion" => "2020-03-01"
    "aid" => "1755"
    "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;U&#46; and Sociedad Espa&#241;ola de Medicina Interna &#40;SEMI&#41;"
    "documento" => "simple-article"
    "crossmark" => 1
    "subdocumento" => "cor"
    "cita" => "Rev Clin Esp. 2020;220:144"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:1 [
      "total" => 0
    ]
    "en" => array:10 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Correspondence</span>"
      "titulo" => "Reply to Montes-Santiago and Roseiro-Sordo&#58; &#8220;The importance of alcohol-related mortality estimates in Spain&#8221;"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:1 [
          "paginaInicial" => "144"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Respuesta a Montes-Santiago y Roseiro-Sordo&#58; &#171;La importancia de las estimaciones de mortalidad relacionadas con el alcohol en Espa&#241;a&#187;"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "S&#46; Trias-Llim&#243;s"
          "autores" => array:1 [
            0 => array:2 [
              "nombre" => "S&#46;"
              "apellidos" => "Trias-Llim&#243;s"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S001425651930270X"
        "doi" => "10.1016/j.rce.2019.09.010"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => false
          "ES2" => false
          "LATM" => false
        ]
        "gratuito" => false
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S001425651930270X?idApp=WRCEE"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2254887419302358?idApp=WRCEE"
    "url" => "/22548874/0000022000000002/v1_202002180732/S2254887419302358/v1_202002180732/en/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S2254887419300104"
    "issn" => "22548874"
    "doi" => "10.1016/j.rceng.2019.01.004"
    "estado" => "S300"
    "fechaPublicacion" => "2020-03-01"
    "aid" => "1603"
    "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;U&#46; and Sociedad Espa&#241;ola de Medicina Interna &#40;SEMI&#41;"
    "documento" => "article"
    "crossmark" => 1
    "subdocumento" => "sco"
    "cita" => "Rev Clin Esp. 2020;220:141-2"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:1 [
      "total" => 0
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Medicine in Images</span>"
      "titulo" => "Endoscopic and histological diagnosis of a case of disseminated tuberculosis with intestinal affectation and lipomembranous fat necrosis"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "141"
          "paginaFinal" => "142"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Diagn&#243;stico endosc&#243;pico e histol&#243;gico de un caso de tuberculosis diseminada con afectaci&#243;n intestinal y necrosis grasa lipomembranosa"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:6 [
          "identificador" => "fig0005"
          "etiqueta" => "Figure 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 805
              "Ancho" => 806
              "Tamanyo" => 89604
            ]
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "J&#46; Yebra Carmona, P&#46; de Mar&#237;a Pallares, L&#46; Blasco Santana"
          "autores" => array:3 [
            0 => array:2 [
              "nombre" => "J&#46;"
              "apellidos" => "Yebra Carmona"
            ]
            1 => array:2 [
              "nombre" => "P&#46;"
              "apellidos" => "de Mar&#237;a Pallares"
            ]
            2 => array:2 [
              "nombre" => "L&#46;"
              "apellidos" => "Blasco Santana"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0014256518303242"
        "doi" => "10.1016/j.rce.2018.11.002"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => false
          "ES2" => false
          "LATM" => false
        ]
        "gratuito" => false
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0014256518303242?idApp=WRCEE"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2254887419300104?idApp=WRCEE"
    "url" => "/22548874/0000022000000002/v1_202002180732/S2254887419300104/v1_202002180732/en/main.assets"
  ]
  "en" => array:15 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Medicine in Images</span>"
    "titulo" => "Fahr&#39;s disease"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:1 [
        "paginaInicial" => "143"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "J&#46;M&#46; Mart&#237;n Guerra, M&#46; Mart&#237;n Asenjo, J&#46;M&#46; Prieto de Paula"
        "autores" => array:3 [
          0 => array:4 [
            "nombre" => "J&#46;M&#46;"
            "apellidos" => "Mart&#237;n Guerra"
            "email" => array:1 [
              0 => "javi6vega@hotmail.com"
            ]
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "&#42;"
                "identificador" => "cor1"
              ]
            ]
          ]
          1 => array:2 [
            "nombre" => "M&#46; Mart&#237;n"
            "apellidos" => "Asenjo"
          ]
          2 => array:2 [
            "nombre" => "J&#46;M&#46;"
            "apellidos" => "Prieto de Paula"
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:2 [
            "entidad" => "Servicio de Medicina Interna&#44; Hospital Cl&#237;nico Universitario de Valladolid&#44; Valladolid&#44; Spain"
            "identificador" => "aff0005"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor1"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Enfermedad de Fahr"
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:6 [
        "identificador" => "fig0005"
        "etiqueta" => "Figure 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 829
            "Ancho" => 900
            "Tamanyo" => 53070
          ]
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">This case concerns a 62-year-old woman with a history of bipolar disorder diagnosed at the age of 39 years undergoing treatment with lithium&#46; Her mother died with dementia&#44; and the patient had a brother with a psychiatric disorder&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">The patient consulted for disorganized behavior&#44; striking hyperactivity and prejudicial ideation towards her husband&#46; The hemogram and biochemistry results were normal&#44; including intact thyrotropin and parathyroid hormone levels&#46; The serology results for toxoplasma&#44; rubella&#44; syphilis&#44; parvovirus B19&#44; varicella-zoster virus and human immunodeficiency virus were negative&#46; Cerebral computed tomography revealed the presence of calcification of the basal ganglia &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">Fahr&#39;s disease&#44; recently renamed primary familial brain calcification &#40;PFBC&#41;&#44; is a neurodegenerative disease in which 4 related genes have been reported &#40;PDGFB&#44; PDGFRB&#44; SLC20A2 and XPR1&#41; and is inherited in an autosomal dominant manner&#46; There are 2 incidence peaks&#58; the third decade of life &#40;characterized by psychotic-like symptoms&#41; and the fifth-sixth decade of life &#40;characterized by progressive dementia and movement disorders&#41;&#46; Cerebral computed tomography is the reference diagnostic test&#44; although a number of authors have suggested diagnostic criteria&#46; The treatment is symptomatic for neuropsychiatric manifestations&#59; however&#44; the use of bisphosphonates has recently been proposed&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">Calcification of the basal ganglia is occasionally a nonspecific finding&#46; In patients with neuropsychiatric symptoms&#44; however&#44; studying the neurodegenerative entities such as PFBC might be appropriate&#44; to thereby offer genetic counseling to affected individuals&#46;</p></span>"
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2018-10-23"
    "fechaAceptado" => "2018-11-02"
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; Mart&#237;n Guerra JM&#44; Asenjo MM&#44; Prieto de Paula JM&#46; Enfermedad de Fahr&#46; Rev Clin Esp&#46; 2020&#59;220&#58;143&#46;</p>"
      ]
    ]
    "multimedia" => array:1 [
      0 => array:6 [
        "identificador" => "fig0005"
        "etiqueta" => "Figure 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 829
            "Ancho" => 900
            "Tamanyo" => 53070
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/22548874/0000022000000002/v1_202002180732/S2254887419300463/v1_202002180732/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "71811"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Medicine in images"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/22548874/0000022000000002/v1_202002180732/S2254887419300463/v1_202002180732/en/main.pdf?idApp=WRCEE&text.app=https://revclinesp.es/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2254887419300463?idApp=WRCEE"
]
Share
Journal Information

Statistics

Follow this link to access the full text of the article

Medicine in Images
Fahr's disease
Enfermedad de Fahr
J.M. Martín Guerra
Corresponding author
javi6vega@hotmail.com

Corresponding author.
, M. Martín Asenjo, J.M. Prieto de Paula
Servicio de Medicina Interna, Hospital Clínico Universitario de Valladolid, Valladolid, Spain
Read
11
Times
was read the article
3
Total PDF
8
Total HTML
Share statistics
 array:24 [
  "pii" => "S2254887419300463"
  "issn" => "22548874"
  "doi" => "10.1016/j.rceng.2019.03.001"
  "estado" => "S300"
  "fechaPublicacion" => "2020-03-01"
  "aid" => "1615"
  "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;U&#46; and Sociedad Espa&#241;ola de Medicina Interna &#40;SEMI&#41;"
  "copyrightAnyo" => "2019"
  "documento" => "article"
  "crossmark" => 1
  "subdocumento" => "sco"
  "cita" => "Rev Clin Esp. 2020;220:143"
  "abierto" => array:3 [
    "ES" => false
    "ES2" => false
    "LATM" => false
  ]
  "gratuito" => false
  "lecturas" => array:1 [
    "total" => 0
  ]
  "Traduccion" => array:1 [
    "es" => array:19 [
      "pii" => "S0014256519300128"
      "issn" => "00142565"
      "doi" => "10.1016/j.rce.2018.11.009"
      "estado" => "S300"
      "fechaPublicacion" => "2020-03-01"
      "aid" => "1615"
      "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;U&#46; and Sociedad Espa&#241;ola de Medicina Interna &#40;SEMI&#41;"
      "documento" => "article"
      "crossmark" => 1
      "subdocumento" => "sco"
      "cita" => "Rev Clin Esp. 2020;220:143"
      "abierto" => array:3 [
        "ES" => false
        "ES2" => false
        "LATM" => false
      ]
      "gratuito" => false
      "lecturas" => array:2 [
        "total" => 16
        "formatos" => array:2 [
          "HTML" => 8
          "PDF" => 8
        ]
      ]
      "es" => array:11 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Medicina en im&#225;genes</span>"
        "titulo" => "Enfermedad de Fahr"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "paginas" => array:1 [
          0 => array:1 [
            "paginaInicial" => "143"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Fahr&#39;s disease"
          ]
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "resumenGrafico" => array:2 [
          "original" => 0
          "multimedia" => array:6 [
            "identificador" => "fig0010"
            "etiqueta" => "Figura 1"
            "tipo" => "MULTIMEDIAFIGURA"
            "mostrarFloat" => true
            "mostrarDisplay" => false
            "figura" => array:1 [
              0 => array:4 [
                "imagen" => "gr1.jpeg"
                "Alto" => 829
                "Ancho" => 900
                "Tamanyo" => 53070
              ]
            ]
          ]
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "J&#46;M&#46; Mart&#237;n Guerra, M&#46; Mart&#237;n Asenjo, J&#46;M&#46; Prieto de Paula"
            "autores" => array:3 [
              0 => array:2 [
                "nombre" => "J&#46;M&#46;"
                "apellidos" => "Mart&#237;n Guerra"
              ]
              1 => array:2 [
                "nombre" => "M&#46;"
                "apellidos" => "Mart&#237;n Asenjo"
              ]
              2 => array:2 [
                "nombre" => "J&#46;M&#46;"
                "apellidos" => "Prieto de Paula"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S2254887419300463"
          "doi" => "10.1016/j.rceng.2019.03.001"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => false
            "ES2" => false
            "LATM" => false
          ]
          "gratuito" => false
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2254887419300463?idApp=WRCEE"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0014256519300128?idApp=WRCEE"
      "url" => "/00142565/0000022000000002/v1_202002140803/S0014256519300128/v1_202002140803/es/main.assets"
    ]
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S2254887419302358"
    "issn" => "22548874"
    "doi" => "10.1016/j.rceng.2019.09.006"
    "estado" => "S300"
    "fechaPublicacion" => "2020-03-01"
    "aid" => "1755"
    "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;U&#46; and Sociedad Espa&#241;ola de Medicina Interna &#40;SEMI&#41;"
    "documento" => "simple-article"
    "crossmark" => 1
    "subdocumento" => "cor"
    "cita" => "Rev Clin Esp. 2020;220:144"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:1 [
      "total" => 0
    ]
    "en" => array:10 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Correspondence</span>"
      "titulo" => "Reply to Montes-Santiago and Roseiro-Sordo&#58; &#8220;The importance of alcohol-related mortality estimates in Spain&#8221;"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:1 [
          "paginaInicial" => "144"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Respuesta a Montes-Santiago y Roseiro-Sordo&#58; &#171;La importancia de las estimaciones de mortalidad relacionadas con el alcohol en Espa&#241;a&#187;"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "S&#46; Trias-Llim&#243;s"
          "autores" => array:1 [
            0 => array:2 [
              "nombre" => "S&#46;"
              "apellidos" => "Trias-Llim&#243;s"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S001425651930270X"
        "doi" => "10.1016/j.rce.2019.09.010"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => false
          "ES2" => false
          "LATM" => false
        ]
        "gratuito" => false
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S001425651930270X?idApp=WRCEE"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2254887419302358?idApp=WRCEE"
    "url" => "/22548874/0000022000000002/v1_202002180732/S2254887419302358/v1_202002180732/en/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S2254887419300104"
    "issn" => "22548874"
    "doi" => "10.1016/j.rceng.2019.01.004"
    "estado" => "S300"
    "fechaPublicacion" => "2020-03-01"
    "aid" => "1603"
    "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;U&#46; and Sociedad Espa&#241;ola de Medicina Interna &#40;SEMI&#41;"
    "documento" => "article"
    "crossmark" => 1
    "subdocumento" => "sco"
    "cita" => "Rev Clin Esp. 2020;220:141-2"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:1 [
      "total" => 0
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Medicine in Images</span>"
      "titulo" => "Endoscopic and histological diagnosis of a case of disseminated tuberculosis with intestinal affectation and lipomembranous fat necrosis"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "141"
          "paginaFinal" => "142"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Diagn&#243;stico endosc&#243;pico e histol&#243;gico de un caso de tuberculosis diseminada con afectaci&#243;n intestinal y necrosis grasa lipomembranosa"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:6 [
          "identificador" => "fig0005"
          "etiqueta" => "Figure 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 805
              "Ancho" => 806
              "Tamanyo" => 89604
            ]
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "J&#46; Yebra Carmona, P&#46; de Mar&#237;a Pallares, L&#46; Blasco Santana"
          "autores" => array:3 [
            0 => array:2 [
              "nombre" => "J&#46;"
              "apellidos" => "Yebra Carmona"
            ]
            1 => array:2 [
              "nombre" => "P&#46;"
              "apellidos" => "de Mar&#237;a Pallares"
            ]
            2 => array:2 [
              "nombre" => "L&#46;"
              "apellidos" => "Blasco Santana"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0014256518303242"
        "doi" => "10.1016/j.rce.2018.11.002"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => false
          "ES2" => false
          "LATM" => false
        ]
        "gratuito" => false
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0014256518303242?idApp=WRCEE"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2254887419300104?idApp=WRCEE"
    "url" => "/22548874/0000022000000002/v1_202002180732/S2254887419300104/v1_202002180732/en/main.assets"
  ]
  "en" => array:15 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Medicine in Images</span>"
    "titulo" => "Fahr&#39;s disease"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:1 [
        "paginaInicial" => "143"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "J&#46;M&#46; Mart&#237;n Guerra, M&#46; Mart&#237;n Asenjo, J&#46;M&#46; Prieto de Paula"
        "autores" => array:3 [
          0 => array:4 [
            "nombre" => "J&#46;M&#46;"
            "apellidos" => "Mart&#237;n Guerra"
            "email" => array:1 [
              0 => "javi6vega@hotmail.com"
            ]
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "&#42;"
                "identificador" => "cor1"
              ]
            ]
          ]
          1 => array:2 [
            "nombre" => "M&#46; Mart&#237;n"
            "apellidos" => "Asenjo"
          ]
          2 => array:2 [
            "nombre" => "J&#46;M&#46;"
            "apellidos" => "Prieto de Paula"
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:2 [
            "entidad" => "Servicio de Medicina Interna&#44; Hospital Cl&#237;nico Universitario de Valladolid&#44; Valladolid&#44; Spain"
            "identificador" => "aff0005"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor1"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Enfermedad de Fahr"
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:6 [
        "identificador" => "fig0005"
        "etiqueta" => "Figure 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 829
            "Ancho" => 900
            "Tamanyo" => 53070
          ]
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">This case concerns a 62-year-old woman with a history of bipolar disorder diagnosed at the age of 39 years undergoing treatment with lithium&#46; Her mother died with dementia&#44; and the patient had a brother with a psychiatric disorder&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">The patient consulted for disorganized behavior&#44; striking hyperactivity and prejudicial ideation towards her husband&#46; The hemogram and biochemistry results were normal&#44; including intact thyrotropin and parathyroid hormone levels&#46; The serology results for toxoplasma&#44; rubella&#44; syphilis&#44; parvovirus B19&#44; varicella-zoster virus and human immunodeficiency virus were negative&#46; Cerebral computed tomography revealed the presence of calcification of the basal ganglia &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">Fahr&#39;s disease&#44; recently renamed primary familial brain calcification &#40;PFBC&#41;&#44; is a neurodegenerative disease in which 4 related genes have been reported &#40;PDGFB&#44; PDGFRB&#44; SLC20A2 and XPR1&#41; and is inherited in an autosomal dominant manner&#46; There are 2 incidence peaks&#58; the third decade of life &#40;characterized by psychotic-like symptoms&#41; and the fifth-sixth decade of life &#40;characterized by progressive dementia and movement disorders&#41;&#46; Cerebral computed tomography is the reference diagnostic test&#44; although a number of authors have suggested diagnostic criteria&#46; The treatment is symptomatic for neuropsychiatric manifestations&#59; however&#44; the use of bisphosphonates has recently been proposed&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">Calcification of the basal ganglia is occasionally a nonspecific finding&#46; In patients with neuropsychiatric symptoms&#44; however&#44; studying the neurodegenerative entities such as PFBC might be appropriate&#44; to thereby offer genetic counseling to affected individuals&#46;</p></span>"
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2018-10-23"
    "fechaAceptado" => "2018-11-02"
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; Mart&#237;n Guerra JM&#44; Asenjo MM&#44; Prieto de Paula JM&#46; Enfermedad de Fahr&#46; Rev Clin Esp&#46; 2020&#59;220&#58;143&#46;</p>"
      ]
    ]
    "multimedia" => array:1 [
      0 => array:6 [
        "identificador" => "fig0005"
        "etiqueta" => "Figure 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 829
            "Ancho" => 900
            "Tamanyo" => 53070
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/22548874/0000022000000002/v1_202002180732/S2254887419300463/v1_202002180732/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "71811"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Medicine in images"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/22548874/0000022000000002/v1_202002180732/S2254887419300463/v1_202002180732/en/main.pdf?idApp=WRCEE&text.app=https://revclinesp.es/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2254887419300463?idApp=WRCEE"
]
Article information
ISSN: 22548874
Original language: English
The statistics are updated each day
Year/Month Html Pdf Total
2023 March 7 3 10
2020 February 1 0 1

Follow this link to access the full text of the article

Idiomas
Revista Clínica Española (English Edition)
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?