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Vol. 213. Issue 6.
Pages 278-284 (August - September 2013)
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Vol. 213. Issue 6.
Pages 278-284 (August - September 2013)
Original article
DOI: 10.1016/j.rceng.2013.05.005
Community-based incidence rate of cardiovascular disease and mortality in 50–75-year-old adults
Incidencia poblacional de la enfermedad cardiovascular y de la mortalidad en los adultos de 50–75 años
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A. López Suárez??
Corresponding author
a.lopez.ssl@gmail.com

Corresponding author.
, A. Bascuñana-Quirell, J. Elvira-González, M. Beltrán-Robles, A. Aboza-Lobatón, R. Solís-Díaz
Hospital Virgen del Camino, Cádiz, Spain
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Figures (1)
Tables (3)
Table 1. Specific density of incidence of new cases of cardiovascular disease and mortality at 5 years (×100,000 individuals/year).
Table 2. Density of incidence of cardiovascular disease and mortality for both genders adjusted for age and for the standard European population (×100,000individuals/year).
Table 3. Cox proportional hazards risk model for the prediction of the combined cardiovascular events variable (coronary disease, cerebrovascular disease and heart failure).
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Abstract
Backgrounds and objectives

Updated information on the incidence of the principal cardiovascular diseases (CVDs) and cardiovascular mortality is not available in Spain. We have studied the density of the incidence of new cases of myocardial infarction, heart failure, stroke and cardiovascular mortality in adults from a population in Sanlúcar de Barrameda (Spain).

Materials and methods

A community-based prospective follow-up study was conducted. The study enrolled 858 participants aged 50–75 years who were randomly selected from the population and followed-up for 5 years. Age and gender-adjusted incidence rates of cardiovascular disease and cardiovascular mortality were calculated, obtaining complete information for 855 participants. Prognostic risk factors of new cases of cardiovascular disease were obtained using Cox proportional hazard modeling.

Results

The community-based incidence rate of heart failure was 455/100,000 persons-year. The incidence of myocardial infarction, stroke and cardiovascular mortality (506, 216 and 225/100,000 persons-year, respectively) was also very elevated. Male gender, family history of early cardiovascular disease, diabetes, hypertension and sedentary life style were independent risk factors of cardiovascular disease.

Conclusions

The incidence of myocardial infarction in Sanlúcar de Barrameda (Spain) is very high. It is the first study reported in Spain. The incidence of myocardial infarction is among the highest in Spain.

Keywords:
Cardiovascular disease incidence
Myocardial infarction
Heart failure
Stroke
Cardiovascular mortality
Cardiovascular risk factors
Resumen
Antecedentes y objetivos

En España no disponemos de una información actualizada sobre la incidencia poblacional de las principales enfermedades cardiovasculares (ECV) y de la mortalidad cardiovascular. Hemos determinado la densidad de incidencia de nuevos casos de infarto de miocardio, ictus, insuficiencia cardiaca y mortalidad cardiovascular en adultos de Sanlúcar de Barrameda.

Material y métodos

Estudio poblacional prospectivo realizado sobre una cohorte de 858 adultos de 50–75 años seleccionados aleatoriamente y seguida durante 5 años. Se calculó la densidad de incidencia de la enfermedad cardiovascular y de la mortalidad cardiovascular ajustada a edad, sexo y a la población estándar europea, consiguiendo información completa de 855 participantes. Mediante el cálculo de riesgos proporcionales de Cox se obtuvieron los factores de riesgo pronósticos de nuevos casos de enfermedad cardiovascular.

Resultados

La incidencia de insuficiencia cardiaca fue de 454/100.000 personas/año. Las incidencias de infarto de miocardio, ictus y mortalidad cardiovascular (506, 216 y 225/100.000 personas/año, respectivamente) también fueron muy elevadas. El sexo masculino, el antecedente familiar de ECV precoz, la diabetes, la hipertensión arterial y el sedentarismo fueron los factores pronósticos independientes de ECV.

Conclusiones

La incidencia poblacional de la insuficiencia cardiaca en Sanlúcar de Barrameda es muy elevada, y es la primera que se comunica en España. La incidencia de infarto de miocardio es de las más elevadas de España.

Palabras clave:
Incidencia de enfermedad cardiovascular
Infarto de miocardio
Insuficiencia cardiaca
Ictus
Mortalidad cardiovascular
Factores de riesgo cardiovascular

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