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"textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Galeano-Valle et al.<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> described a cohort of patients with cerebral venous sinus thrombosis (CVST). They analysed complications via a composite event, observing how cerebral oedema and corticosteroid therapy are associated with more complications while headache and involvement of the superior sagittal sinus are associated with a lower risk of complications. In the literature, these characteristics are not considered to be predictors of a worse prognosis or sequelae.</p><p id="par0010" class="elsevierStylePara elsevierViewall">Early mortality in CVST typically occurs due to transtentorial herniation owing to large intracranial space-occupying lesions or to generalised cerebral oedema. Long-term mortality is mainly due to underlying disease (cancer in particular), haemorrhagic complications associated with prolonged anticoagulant therapy, or recurrent thrombosis.</p><p id="par0015" class="elsevierStylePara elsevierViewall">The ISCVT study<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> identified the following factors for poor prognosis among CVST patients: age over 37 years, male sex, coma, presence of intracranial haemorrhage, central nervous system infection, neoplasm, and deep involvement of the cerebral venous system. A systematic review<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> observed an association between persistent venous occlusion and worse functional outcome. Galeano-Valle et al.<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> likely did not encounter these findings due to the reduced sample size of their cohort.</p><p id="par0020" class="elsevierStylePara elsevierViewall">Another interesting aspect to bear in mind regarding patients with CVST is that, while approximately 80% of patients recover without any functional disability, many experience in the long-term chronic headaches,<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> neuropsychological deficits, or depression, as well as feelings of isolation on account of being a young “stroke” survivor, with the resulting negative impact on their day-to-day life.<a class="elsevierStyleCrossRefs" href="#bib0010"><span class="elsevierStyleSup">2,5</span></a> Perhaps future studies could develop scales for both physical and psychological symptoms during follow-up to help identify the most significant sequelae that affect quality of life following CVST.</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflicts of interest</span><p id="par0025" class="elsevierStylePara elsevierViewall">The author states she has no conflicts of interest regarding this article.</p></span></span>"
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