Journal Information
Vol. 222. Issue 5.
Pages 288-292 (May 2022)
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Vol. 222. Issue 5.
Pages 288-292 (May 2022)
Brief Original
Clinical characteristics and comorbidities associated with mortality in patients with COVID-19 in Coahuila (Mexico)
Características clínicas y comorbilidades asociadas a mortalidad en pacientes con COVID-19 en Coahuila (México)
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J.E. Salinas-Aguirre, C. Sánchez-García
Corresponding author
sanchez.carlos8516@gmail.com

Corresponding author.
, R. Rodríguez-Sanchez, L. Rodríguez-Muñoz, A. Díaz-Castaño, R. Bernal-Gómez
Secretaría de Salud del Estado de Coahuila de Zaragoza, Coahuila de Zaragoza, Mexico
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Tables (2)
Table 1. Characteristics of patients with COVID-19.
Table 2. Risk factors associated with mortality in patients with COVID-19.
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Abstract
Background and objective

This study aims to describe the characteristics of patients with COVID-19 in a state in northern Mexico and establish the comorbidities associated with mortality.

Methods

Patients with COVID-19, divided into survivors and non-survivors, were analyzed. The data were analyzed using the chi-square test, Student’s t-test, and Cox’s regression model.

Results

A total of 17,479 patients were included and mortality rate of 6.3% was reported. Age over 60 years (HR = 8.04; 95%CI 7.03–9.19), diabetes (HR = 1.63; 95%CI 1.40–1.89), high blood pressure (HR = 1.48; 95%CI 1.28–1.72), obesity (HR = 1.37; 95%CI 1.18–1.60) and chronic kidney disease (HR = 2.06; 95%CI 1.64–2.59) were significantly associated with mortality.

Conclusions

Diabetes, high blood pressure, obesity, and chronic kidney disease increased mortality among patients with COVID-19 in the population of Coahuila, Mexico. The factor that most contributed to risk of death was age over 60 years.

Keywords:
Comorbidities
Mortality
Risk factors
COVID-19
Resumen
Antecedentes y objetivo

El objetivo de este estudio es describir las características de los pacientes con COVID-19 en un estado del norte de México y determinar las comorbilidades asociadas con la mortalidad.

Métodos

Se examinaron pacientes con COVID-19, divididos en supervivientes y no supervivientes. Los datos fueron analizados mediante las pruebas de X2, t de Student y el modelo de regresión de Cox.

Resultados

Se incluyeron 17.479 pacientes, reportando un 6,3% de mortalidad. Los factores que se asociaron con esta fueron: edad mayor a 60 años (HR = 8,04; IC 95% 7,03 a 9,19), diabetes (HR = 1,63; IC 95% 1,40 a 1,89), hipertensión arterial sistémica (HR = 1,48; IC 95% 1,28 a 1,72), obesidad (HR = 1,37; IC 95% 1,18 a 1,60) y daño renal crónico (HR = 2,06; IC 95% 1,64 a 2,59).

Conclusiones

La diabetes, la hipertensión arterial, la obesidad y el daño renal crónico incrementan la mortalidad en pacientes con COVID-19 en la población de Coahuila, México; el factor que más contribuye para el riesgo de muerte es la edad mayor a 60 años.

Palabras clave:
Comorbilidades
Mortalidad
Factores de riesgo
COVID-19

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