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Villafuerte.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "E. Garrido, J. Botella de Maglia, O. Castillo" "autores" => array:3 [ 0 => array:2 [ "nombre" => "E." "apellidos" => "Garrido" ] 1 => array:2 [ "nombre" => "J." "apellidos" => "Botella de Maglia" ] 2 => array:2 [ "nombre" => "O." 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Robles Marhuenda, J. Molina Collada, F. Arnalich Fernández" "autores" => array:3 [ 0 => array:4 [ "nombre" => "Á." "apellidos" => "Robles Marhuenda" "email" => array:1 [ 0 => "aroblesmarhuenda@gmail.com" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "J." "apellidos" => "Molina Collada" ] 2 => array:2 [ "nombre" => "F." "apellidos" => "Arnalich Fernández" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Servicio de Medicina Interna, Hospital Universitario La Paz, Madrid, España" "identificador" => "aff0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Autor para correspondencia." ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Yellow nails syndrome" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:6 [ "identificador" => "fig0010" "etiqueta" => "Figura 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 905 "Ancho" => 905 "Tamanyo" => 39474 ] ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Un varón de 72 años fue derivado a nuestro hospital por fiebre, empeoramiento de su disnea e historial de infecciones pulmonares recurrentes. El paciente, exfumador caucásico, carecía de exposición ocupacional. La exploración física, únicamente reveló crepitantes finos en los ambos campos pulmonares inferiores y uñas engrosadas, con coloración amarillenta, curvatura excesiva y crecimiento anormalmente lento (<a class="elsevierStyleCrossRef" href="#fig0005">fig. 1</a>). El paciente refería episodios de edema en los miembros superiores, especialmente al atardecer, y previos a las exacerbaciones respiratorias. La radiografía de tórax mostró bronquiectasias (<a class="elsevierStyleCrossRef" href="#fig0010">fig. 2</a>) afectando a los lóbulos inferiores bilateralmente, y pinzamiento del ángulo costofrénico izquierdo. Los cultivos para hongos de las uñas no demostraron crecimiento microbiano. El síndrome de uñas amarillas es un trastorno poco frecuente de causa desconocida caracterizado por la tríada de uñas amarillas y engrosadas, linfedema y manifestaciones respiratorias<a class="elsevierStyleCrossRefs" href="#bib0025"><span class="elsevierStyleSup">1,2</span></a>. Los datos disponibles sugieren que la presencia de una disfunción linfática adquirida es el mecanismo predominante que subyace en dichas manifestaciones clínicas<a class="elsevierStyleCrossRefs" href="#bib0035"><span class="elsevierStyleSup">3,4</span></a>.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2019-07-15" "fechaAceptado" => "2019-07-25" "multimedia" => array:2 [ 0 => array:6 [ "identificador" => "fig0005" "etiqueta" => "Figura 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 603 "Ancho" => 905 "Tamanyo" => 36892 ] ] ] 1 => array:6 [ "identificador" => "fig0010" "etiqueta" => "Figura 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 905 "Ancho" => 905 "Tamanyo" => 39474 ] ] ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0015" "bibliografiaReferencia" => array:4 [ 0 => array:3 [ "identificador" => "bib0025" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The yellow nail syndrome" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "P.D. Samman" 1 => "W.F. White" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1365-2133.1964.tb14499.x" "Revista" => array:6 [ "tituloSerie" => "Br J Dermatol" "fecha" => "1964" "volumen" => "76" "paginaInicial" => "153" "paginaFinal" => "157" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14140738" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0030" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Yellow nails, lymphoedema, and pleural effusions" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "P.A. Emerson" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1136/thx.21.3.247" "Revista" => array:7 [ "tituloSerie" => "Thorax" "fecha" => "1966" "volumen" => "21" "paginaInicial" => "247" "paginaFinal" => "253" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5914998" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0190962219305882" "estado" => "S300" "issn" => "01909622" ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0035" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Yellow nail syndrome: Does protein leakage play a role?" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "A. D’Alessandro" 1 => "G. Muzi" 2 => "A. Monaco" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1183/09031936.01.17101490" "Revista" => array:6 [ "tituloSerie" => "Eur Respir J" "fecha" => "2001" "volumen" => "17" "paginaInicial" => "149" "paginaFinal" => "152" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11307745" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0040" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Nailing the diagnosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "S. Rajagopala" 1 => "N. Singh" 2 => "D. 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