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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Chronic obstructive pulmonary disease &#40;COPD&#41; is a preventable and treatable disease characterised by persistent respiratory symptoms and limited airflow due to alveolar and&#47;or airway abnormalities&#44; generally caused by significant exposure to noxious particles and influenced by host factors&#44; including abnormal lung development&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">COPD represents an important public health challenge and is a significant cause of morbidity and mortality and public health care costs&#46; In 2019 it was estimated that 212 million patients were diagnosed with COPD around the world with over 3&#46;2 million deaths each year&#44; representing the third cause of death &#40;6&#37; of deaths&#41; and the sixth in terms of disease burden&#46;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> The projections indicate that the burden of COPD will increase in coming decades due to continuous exposure to the disease&#8217;s risk factors and to population ageing&#46;<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">COPD is the most prevalent non-communicable respiratory disease and has reached pandemic levels&#46; The data on the real prevalence of COPD varies broadly due to differences in diagnostic and inclusion criteria and significant geographic variability&#44; with a prevalence of diagnosed cases that ranges from 6&#37; in Europe to 1&#46;6&#37; in sub-Saharan Africa&#46;<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> A good example of this is the study published by Wang et al&#46; that was conducted in the vast Shanxi province &#40;China&#41;&#44; where a prevalence of 6&#46;4&#37; was observed&#44;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> though the results could be biased as it included an excessively young population &#40;&#8805;20 years&#41;&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">Fortunately&#44; we currently have data that enables us to estimate the prevalence of COPD more accurately&#44; such as the Burden of Obstructive Lung Diseases &#40;BOLD&#41; program that uses a standardised methodology to evaluate the prevalence and risk factors of COPD in individuals over the age of 40 across the world&#46;<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a> According to BOLD&#44; the number of real cases of COPD in 2010 was estimated to be 384 million&#44; with a global prevalence of 11&#46;7&#37;&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a></p><p id="par0025" class="elsevierStylePara elsevierViewall">In Spain&#44; recent data from the EPISCAN II study show a prevalence of 11&#46;8&#37; in patients over the age of 40&#44; with significant regional differences and a predominance in males &#40;14&#46;6&#37;&#41; over females &#40;9&#46;4&#37;&#41;&#46; This latter group is increasingly growing as it progressively adopts smoking habits&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">7</span></a> This prevalence is higher than that of other diseases such as diabetes mellitus and yet&#44; we continue to fail to pay enough attention to our respiratory health&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">The two basic pillars in the fight against this epidemic are interventions to prevent risk factors and early diagnosis of the disease&#46; The main risk factors for COPD are smoking&#44; presence of respiratory symptoms &#40;wheezing&#44; asthma and&#47;or chronic bronchitis&#41; and a history of sinusitis or nasal polyps&#46;<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">8</span></a></p><p id="par0035" class="elsevierStylePara elsevierViewall">In our setting&#44; prevention should be focused on fighting smoking&#46; According to the European Health Survey&#44; in Spain&#44; 16&#46;4&#37; of females and 23&#46;3&#37; of males smoke on a daily basis&#46;<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">9</span></a> The strategy should be focused around preventing starting smoking and helping current smokers to stop smoking&#46; For this reason&#44; the current anti-smoking law from 2010 needs to be revised to help stop tobacco use&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">In terms of early diagnosis&#44; the significant underdiagnosis of COPD is a crucial issue&#44; estimated to be around 74&#46;7&#37; in Spain according to the EPISCAN II data&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">7</span></a> This means that up to 70&#37; of COPD patients are diagnosed in advanced stages of the disease when the possibility to improve prognosis is much more limited&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a></p><p id="par0045" class="elsevierStylePara elsevierViewall">To reduce underdiagnosis&#44; our GesEPOC national guidelines continue to recommend the use of screening questionnaires and spirometry in adults over 35 years&#44; smokers&#44; or ex-smokers with respiratory symptoms&#46;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">10</span></a> However&#44; it is necessary to evaluate new strategies regarding both the use of simpler screening methods than spirometry and a definition of the target population for screening&#46; For the former&#44; this includes the use of questionnaires&#44; portable spirometers&#44; or peak flow meters as well as more innovative techniques&#44; such as analysing breathing sounds recorded by smartphones&#44; which are already being implemented in initiatives to anticipate diagnosis and treatment of this disease such as the ANTES multi-centre strategy&#46;<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">11</span></a> Regarding the latter&#44; advances must be made in the analysis of the cost effectiveness of screening in diseases like ischaemic heart disease&#44; diabetes&#44; or sinusitis&#44; where the prevalence of COPD is very high and screening opportunistic&#46;</p><p id="par0050" class="elsevierStylePara elsevierViewall">In short&#44; if we want to make progress in the fight against COPD&#44; we must strengthen measures to reduce tobacco use and once and for all define strategies that enable hidden cases of the disease to come to the surface&#46;</p></span>"
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              "etiqueta" => "4"
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                            2 => "R&#46; Wang"
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              "identificador" => "bib0030"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
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                    0 => array:2 [
                      "titulo" => "Global and regional estimates of COPD prevalence&#58; systematic review and meta-analysis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "D&#46; Adeloye"
                            1 => "S&#46; Chua"
                            2 => "C&#46; Lee"
                            3 => "C&#46; Basquill"
                            4 => "A&#46; Papana"
                            5 => "E&#46; Theodoratou"
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                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.7189/jogh.05-020415"
                      "Revista" => array:3 [
                        "tituloSerie" => "J Glob Health"
                        "fecha" => "2015"
                        "volumen" => "5"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0035"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prevalence and determinants of COPD in Spain EPISCAN II"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "J&#46; Soriano"
                            1 => "I&#46; Alfageme"
                            2 => "M&#46; Miravitlles"
                            3 => "P&#46; de Lucas"
                            4 => "J&#46;J&#46; Soler-Catalu&#241;a"
                            5 => "F&#46; Garc&#237;a-Rio"
                          ]
                        ]
                      ]
                    ]
                  ]
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                    0 => array:2 [
                      "doi" => "10.1016/j.arbres.2020.07.024"
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                        "tituloSerie" => "Arch Bronconeumol"
                        "fecha" => "2021"
                        "volumen" => "57"
                        "paginaInicial" => "61"
                        "paginaFinal" => "69"
                        "link" => array:1 [
                          0 => array:2 [
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                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
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              "etiqueta" => "8"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Factors associated with low lung function in different age bins in the general population"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "R&#46; Breyer-Kohansal"
                            1 => "R&#46; Faner"
                            2 => "M&#46;-K&#46; Breyer"
                            3 => "A&#46; Ofenheimer"
                            4 => "A&#46; Schrott"
                            5 => "M&#46; Studnicka"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1164/rccm.202001-0172LE"
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                        "tituloSerie" => "Am J Respir Crit Care Med"
                        "fecha" => "2020"
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                        "paginaFinal" => "329"
                        "link" => array:1 [
                          0 => array:2 [
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                            "web" => "Medline"
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              ]
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              "etiqueta" => "10"
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                      "titulo" => "Gu&#237;a de Pr&#225;ctica Cl&#237;nica para el Diagn&#243;stico y Tratamiento de Pacientes con Enfermedad Pulmonar Obstructiva Cr&#243;nica &#40;EPOC&#41;-Gu&#237;a Espa&#241;ola de la EPOC &#40;GesEPOC&#41; Versi&#243;n 2017"
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                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Arch Bronconeumol"
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                        "paginaFinal" => "64"
                      ]
                    ]
                  ]
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              "identificador" => "bib0055"
              "etiqueta" => "11"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Time for a change&#58; anticipating the diagnosis and treatment of COPD"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "A&#46; Agusti"
                            1 => "B&#46; Alcazar"
                            2 => "B&#46; Cosio"
                            3 => "J&#46;M&#46; Echave"
                            4 => "R&#46; Faner"
                            5 => "J&#46;L&#46; Izquierdo"
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                      ]
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Editorial
COPD: A preventable epidemic?
EPOC: ¿una epidemia prevenible?
J.M. Varela-Aguilara,b,c,d, F.J. Medrano-Ortegaa,b,c,d,e,
Corresponding author
medrano@cica.es

Corresponding author.
a Servicio de Medicina Interna, Hospital Universitario Virgen del Rocío, Sevilla, Spain
b Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Spain
c Instituto de Biomedicina de Sevilla, Sevilla, Spain
d Grupo de Trabajo de EPOC de la Sociedad Española de Medicina Interna, Spain
e Departamento de Medicina, Universidad de Sevilla, Sevilla, Spain
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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Chronic obstructive pulmonary disease &#40;COPD&#41; is a preventable and treatable disease characterised by persistent respiratory symptoms and limited airflow due to alveolar and&#47;or airway abnormalities&#44; generally caused by significant exposure to noxious particles and influenced by host factors&#44; including abnormal lung development&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">COPD represents an important public health challenge and is a significant cause of morbidity and mortality and public health care costs&#46; In 2019 it was estimated that 212 million patients were diagnosed with COPD around the world with over 3&#46;2 million deaths each year&#44; representing the third cause of death &#40;6&#37; of deaths&#41; and the sixth in terms of disease burden&#46;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> The projections indicate that the burden of COPD will increase in coming decades due to continuous exposure to the disease&#8217;s risk factors and to population ageing&#46;<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">COPD is the most prevalent non-communicable respiratory disease and has reached pandemic levels&#46; The data on the real prevalence of COPD varies broadly due to differences in diagnostic and inclusion criteria and significant geographic variability&#44; with a prevalence of diagnosed cases that ranges from 6&#37; in Europe to 1&#46;6&#37; in sub-Saharan Africa&#46;<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> A good example of this is the study published by Wang et al&#46; that was conducted in the vast Shanxi province &#40;China&#41;&#44; where a prevalence of 6&#46;4&#37; was observed&#44;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> though the results could be biased as it included an excessively young population &#40;&#8805;20 years&#41;&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">Fortunately&#44; we currently have data that enables us to estimate the prevalence of COPD more accurately&#44; such as the Burden of Obstructive Lung Diseases &#40;BOLD&#41; program that uses a standardised methodology to evaluate the prevalence and risk factors of COPD in individuals over the age of 40 across the world&#46;<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a> According to BOLD&#44; the number of real cases of COPD in 2010 was estimated to be 384 million&#44; with a global prevalence of 11&#46;7&#37;&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a></p><p id="par0025" class="elsevierStylePara elsevierViewall">In Spain&#44; recent data from the EPISCAN II study show a prevalence of 11&#46;8&#37; in patients over the age of 40&#44; with significant regional differences and a predominance in males &#40;14&#46;6&#37;&#41; over females &#40;9&#46;4&#37;&#41;&#46; This latter group is increasingly growing as it progressively adopts smoking habits&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">7</span></a> This prevalence is higher than that of other diseases such as diabetes mellitus and yet&#44; we continue to fail to pay enough attention to our respiratory health&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">The two basic pillars in the fight against this epidemic are interventions to prevent risk factors and early diagnosis of the disease&#46; The main risk factors for COPD are smoking&#44; presence of respiratory symptoms &#40;wheezing&#44; asthma and&#47;or chronic bronchitis&#41; and a history of sinusitis or nasal polyps&#46;<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">8</span></a></p><p id="par0035" class="elsevierStylePara elsevierViewall">In our setting&#44; prevention should be focused on fighting smoking&#46; According to the European Health Survey&#44; in Spain&#44; 16&#46;4&#37; of females and 23&#46;3&#37; of males smoke on a daily basis&#46;<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">9</span></a> The strategy should be focused around preventing starting smoking and helping current smokers to stop smoking&#46; For this reason&#44; the current anti-smoking law from 2010 needs to be revised to help stop tobacco use&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">In terms of early diagnosis&#44; the significant underdiagnosis of COPD is a crucial issue&#44; estimated to be around 74&#46;7&#37; in Spain according to the EPISCAN II data&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">7</span></a> This means that up to 70&#37; of COPD patients are diagnosed in advanced stages of the disease when the possibility to improve prognosis is much more limited&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a></p><p id="par0045" class="elsevierStylePara elsevierViewall">To reduce underdiagnosis&#44; our GesEPOC national guidelines continue to recommend the use of screening questionnaires and spirometry in adults over 35 years&#44; smokers&#44; or ex-smokers with respiratory symptoms&#46;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">10</span></a> However&#44; it is necessary to evaluate new strategies regarding both the use of simpler screening methods than spirometry and a definition of the target population for screening&#46; For the former&#44; this includes the use of questionnaires&#44; portable spirometers&#44; or peak flow meters as well as more innovative techniques&#44; such as analysing breathing sounds recorded by smartphones&#44; which are already being implemented in initiatives to anticipate diagnosis and treatment of this disease such as the ANTES multi-centre strategy&#46;<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">11</span></a> Regarding the latter&#44; advances must be made in the analysis of the cost effectiveness of screening in diseases like ischaemic heart disease&#44; diabetes&#44; or sinusitis&#44; where the prevalence of COPD is very high and screening opportunistic&#46;</p><p id="par0050" class="elsevierStylePara elsevierViewall">In short&#44; if we want to make progress in the fight against COPD&#44; we must strengthen measures to reduce tobacco use and once and for all define strategies that enable hidden cases of the disease to come to the surface&#46;</p></span>"
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            0 => array:3 [
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              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "2022 reports&#46; Global strategy for prevention&#44; diagnosis and management of COPD"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "Global Initiative for Chronic Obstructive Lung Disease"
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            1 => array:3 [
              "identificador" => "bib0010"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Global burden of 369 diseases and injuries in 204 countries and territories&#44; 1990-2019&#58; a systematic analysis for the Global Burden of Disease Study 2019"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "GBD 2019 Diseases and Injuries Collaborators"
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                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/S0140-6736(20)30925-9"
                      "Revista" => array:6 [
                        "tituloSerie" => "Lancet"
                        "fecha" => "2020"
                        "volumen" => "396"
                        "paginaInicial" => "1204"
                        "paginaFinal" => "1222"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/33069326"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0015"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prevalence and attributable health burden of chronic respiratory diseases&#44; 1990-2017&#58; a systematic analysis for the Global Burden of Disease Study 2017"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "GBD Chronic Respiratory Disease Collaborators"
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                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/S2213-2600(20)30105-3"
                      "Revista" => array:6 [
                        "tituloSerie" => "Lancet Respir Med"
                        "fecha" => "2020"
                        "volumen" => "8"
                        "paginaInicial" => "585"
                        "paginaFinal" => "596"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/32526187"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0020"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Encuesta poblacional sobre la prevalencia y los factores de riesgo de la enfermedad pulmonar obstructiva cr&#243;nica en la provincia de Shanxi &#40;China&#41;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "R&#46; Wang"
                            1 => "J&#46; Xu"
                            2 => "R&#46; Wang"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Rev Clin Esp"
                        "fecha" => "2022"
                        "volumen" => "222"
                        "paginaInicial" => "218"
                        "paginaFinal" => "221"
                      ]
                    ]
                  ]
                ]
              ]
            ]
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                0 => array:1 [
                  "referenciaCompleta" => "BOLD&#46; Burden of Obstructive Lung Disease Initiative Webpage&#44; published by Imperial College London&#46; Available from&#58; <a target="_blank" href="http://www.boldstudy.org/">http&#58;&#47;&#47;www&#46;boldstudy&#46;org&#47;</a>&#46; &#91;Accessed 30 January 2022&#93;&#46;"
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              ]
            ]
            5 => array:3 [
              "identificador" => "bib0030"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Global and regional estimates of COPD prevalence&#58; systematic review and meta-analysis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "D&#46; Adeloye"
                            1 => "S&#46; Chua"
                            2 => "C&#46; Lee"
                            3 => "C&#46; Basquill"
                            4 => "A&#46; Papana"
                            5 => "E&#46; Theodoratou"
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                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.7189/jogh.05-020415"
                      "Revista" => array:3 [
                        "tituloSerie" => "J Glob Health"
                        "fecha" => "2015"
                        "volumen" => "5"
                      ]
                    ]
                  ]
                ]
              ]
            ]
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              "etiqueta" => "7"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prevalence and determinants of COPD in Spain EPISCAN II"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "J&#46; Soriano"
                            1 => "I&#46; Alfageme"
                            2 => "M&#46; Miravitlles"
                            3 => "P&#46; de Lucas"
                            4 => "J&#46;J&#46; Soler-Catalu&#241;a"
                            5 => "F&#46; Garc&#237;a-Rio"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.arbres.2020.07.024"
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Bronconeumol"
                        "fecha" => "2021"
                        "volumen" => "57"
                        "paginaInicial" => "61"
                        "paginaFinal" => "69"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/32950310"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
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              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Factors associated with low lung function in different age bins in the general population"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "R&#46; Breyer-Kohansal"
                            1 => "R&#46; Faner"
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                            3 => "A&#46; Ofenheimer"
                            4 => "A&#46; Schrott"
                            5 => "M&#46; Studnicka"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1164/rccm.202001-0172LE"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Respir Crit Care Med"
                        "fecha" => "2020"
                        "volumen" => "202"
                        "paginaInicial" => "292"
                        "paginaFinal" => "329"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/32255673"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
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              "identificador" => "bib0045"
              "etiqueta" => "9"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Instituto Nacional de Estad&#237;stica&#46; Encuesta Europea de Salud en Espa&#241;a&#46; Available from&#58; <a target="_blank" href="https://www.ine.es/dyngs/INEbase/es/operacion.htm?c=Estadistica_C&amp;cid=1254736176784&amp;menu=resultados&amp;idp=1254735573175">https&#58;&#47;&#47;www&#46;ine&#46;es&#47;dyngs&#47;INEbase&#47;es&#47;operacion&#46;htm&#63;c&#61;Estadistica&#95;C&#38;cid&#61;1254736176784&#38;menu&#61;resultados&#38;idp&#61;1254735573175</a>&#46; &#91;Accessed 6 February 2022&#93;&#46;"
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              ]
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              "etiqueta" => "10"
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                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Gu&#237;a de Pr&#225;ctica Cl&#237;nica para el Diagn&#243;stico y Tratamiento de Pacientes con Enfermedad Pulmonar Obstructiva Cr&#243;nica &#40;EPOC&#41;-Gu&#237;a Espa&#241;ola de la EPOC &#40;GesEPOC&#41; Versi&#243;n 2017"
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                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Arch Bronconeumol"
                        "fecha" => "2017"
                        "volumen" => "53 Supl 1"
                        "paginaInicial" => "1"
                        "paginaFinal" => "64"
                      ]
                    ]
                  ]
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                0 => array:2 [
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                      "titulo" => "Time for a change&#58; anticipating the diagnosis and treatment of COPD"
                      "autores" => array:1 [
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                          "etal" => true
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                            1 => "B&#46; Alcazar"
                            2 => "B&#46; Cosio"
                            3 => "J&#46;M&#46; Echave"
                            4 => "R&#46; Faner"
                            5 => "J&#46;L&#46; Izquierdo"
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Article information
ISSN: 22548874
Original language: English
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