Medicine in Images
Corneal involvement due to Erdheim-Chester disease
Afectación corneal debido a enfermedad de Erdheim-Chester
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Díez de los Ríos, J. Serra Batlles, F. Ruiz" "autores" => array:3 [ 0 => array:4 [ "nombre" => "J." "apellidos" => "Díez de los Ríos" "email" => array:1 [ 0 => "jdiez@chv.cat" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor1" ] ] ] 1 => array:3 [ "nombre" => "J." "apellidos" => "Serra Batlles" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "F." "apellidos" => "Ruiz" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio de Medicina Interna, Hospital Universitario de Vic, Vic, Barcelona, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicio de Neumología, Hospital Universitario de Vic, Vic, Barcelona, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Afectación corneal debido a enfermedad de Erdheim-Chester" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:6 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 317 "Ancho" => 1250 "Tamanyo" => 56895 ] ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">We present the case of a 50-year-old man with a medical history of Erdheim-Chester disease diagnosed in 1992, with multiple organ involvement (corneal, skin, neurological, bone and vascular), who was hospitalized for symptoms of dry cough and dyspnea with acute respiratory failure. The patient was diagnosed with interstitial lung disease. The physical examination revealed corneal infiltration by histiocytes (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>), previously treated with corneal transplantation, with subsequent graft rejection, resulting in blindness.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">After being discharged and due to ocular pain, the patient underwent surgery to enucleate both eyes. The biopsy of the right globe showed non-necrotizing xanthogranulomatous inflammation affecting the cornea and focally affecting the sclera, with obliteration of the anterior chamber. The biopsy of the left globe showed non-necrotizing xanthogranulomatous inflammation affecting the sclera and the irido-sclero-corneal angle. The morphological changes were consistent with Erdheim-Chester disease, a rare histiocytosis of non-Langerhans cells characterized by multisystem infiltration by epithelioid cells and foamy histiocytes. Approximately 700 cases have been described in the literature. Intraocular manifestations are extremely rare, with 5 published cases (4 with choroid infiltration and one with subretinal infiltration). Our case exceptionally presented corneal involvement, which has not been previously reported.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2018-06-04" "fechaAceptado" => "2018-07-16" "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Díez de los Ríos J, Serra Batlles J, Ruiz F. Afectación corneal debido a enfermedad de Erdheim-Chester. Rev Clín Esp. 2019;219:515.</p>" ] ] "multimedia" => array:1 [ 0 => array:6 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 317 "Ancho" => 1250 "Tamanyo" => 56895 ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/22548874/0000021900000009/v3_201912041809/S2254887418301802/v3_201912041809/en/main.assets" "Apartado" => array:4 [ "identificador" => "71811" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Medicine in images" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/22548874/0000021900000009/v3_201912041809/S2254887418301802/v3_201912041809/en/main.pdf?idApp=WRCEE&text.app=https://revclinesp.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2254887418301802?idApp=WRCEE" ]
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