Medicine in Images
Metastatic melanoma-asociated poliosis
Poliosis asociada a melanoma metastásico
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"apellidos" => "Parejo-Morón" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio de Medicina Interna, Hospital Universitario San Cecilio, Granada, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicio de Anatomía Patológica, Hospital Universitario San Cecilio, Granada, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Poliosis asociada a melanoma metastásico" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:6 [ "identificador" => "fig0020" "etiqueta" => "Figure 4" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr4.jpeg" "Alto" => 718 "Ancho" => 900 "Tamanyo" => 296832 ] ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Poliosis is defined as hair depigmentation, typically that of eyebrows, eyelashes and scalp, and its acute onset is related to melanocytic lesions or the taking of drugs. We present the case of a 74-year-old man who was admitted to the emergency department complaining of pain in the left arm after mild trauma. Radiography revealed a lytic lesion in the left humerus complicated by a pathologic fracture. The examination revealed that the patient presented eyebrow, eyelash and scalp depigmentation (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>), which, according to the patient, had started abruptly the previous month. We also observed stony lymph nodes attached to the right retroauricular, axillary, cervical and inguinal regions, as well as a purplish nodular infraareolar lesion (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>). We performed a bone biopsy and a biopsy of the infraareolar lesion, which resulted as a melanoma of superficial metastatic extension (<a class="elsevierStyleCrossRefs" href="#fig0015">Figs. 3 and 4</a>). An extension study showed lung, liver, soft tissue and bone involvement, as well as subcutaneous metastases. This involvement was attributed to a melanoma of superficial extension, which was removed 3 years ago in the right inguinal region, with lesion-free edges. Poliosis as a manifestation of metastatic melanoma has been reported in the literature, although there have been few published cases. We report our case because it illustrates an atypical manifestation of this entity.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia><elsevierMultimedia ident="fig0020"></elsevierMultimedia></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2018-05-08" "fechaAceptado" => "2018-07-16" "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Fernández-Díaz MR, Trigo-Rodriguez M, Faro-Miguez N, Aneiros-Fernández J, Parejo-Morón AI. Poliosis asociada a melanoma metastásico. Rev Clín Esp. 2018. <span class="elsevierStyleInterRef" id="intr0005" href="https://doi.org/10.1016/j.rce.2018.07.004">https://doi.org/10.1016/j.rce.2018.07.004</span></p>" ] ] "multimedia" => array:4 [ 0 => array:6 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 675 "Ancho" => 900 "Tamanyo" => 105124 ] ] ] 1 => array:6 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 1200 "Ancho" => 900 "Tamanyo" => 250606 ] ] ] 2 => array:6 [ "identificador" => "fig0015" "etiqueta" => "Figure 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 657 "Ancho" => 900 "Tamanyo" => 325631 ] ] ] 3 => array:6 [ "identificador" => "fig0020" "etiqueta" => "Figure 4" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr4.jpeg" "Alto" => 718 "Ancho" => 900 "Tamanyo" => 296832 ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/22548874/0000021900000007/v1_201912172116/S2254887418301462/v1_201912172116/en/main.assets" "Apartado" => array:4 [ "identificador" => "71811" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Medicine in images" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/22548874/0000021900000007/v1_201912172116/S2254887418301462/v1_201912172116/en/main.pdf?idApp=WRCEE&text.app=https://revclinesp.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2254887418301462?idApp=WRCEE" ]
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