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        "titulo" => "Prevalencia de obesidad seg&#250;n la estadificaci&#243;n de Edmonton en las consultas de Medicina Interna&#46; Resultados del estudio OBEMI"
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          "en" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Study flow diagram&#46; BMI&#44; body mass index&#59; EOS&#44; Edmonton Obesity Staging System&#46;</p>"
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    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0065">Background</span><p id="par0005" class="elsevierStylePara elsevierViewall">In recent decades&#44; obesity has reached worldwide epidemic proportions&#46; Twenty percent of the population has excess weight&#44; and 10&#37; have obesity&#44; with figures for 2030 estimated at 2&#46;16 million individuals with excess weight and 1&#46;12 million with obesity&#46;<a class="elsevierStyleCrossRef" href="#bib0155"><span class="elsevierStyleSup">1</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">The prevalence of obesity in the adult population in Spain is approximately 23&#37;&#46;<a class="elsevierStyleCrossRef" href="#bib0160"><span class="elsevierStyleSup">2</span></a> Most epidemiological studies have used the body mass index &#40;BMI&#41; &#40;weight in kg&#47;height in meters<a class="elsevierStyleCrossRef" href="#bib0160"><span class="elsevierStyleSup">2</span></a>&#41; to classify obesity&#46;<a class="elsevierStyleCrossRef" href="#bib0165"><span class="elsevierStyleSup">3</span></a> An individual over the age of 18 years with a BMI<span class="elsevierStyleHsp" style=""></span>&#8805;30<span class="elsevierStyleHsp" style=""></span>kg&#47;m<span class="elsevierStyleSup">2</span> is considered to have obesity&#46; However&#44; obesity can also be defined by other criteria&#44; such as an excess of adipose tissue &#40;25&#37; in men and 30&#37; in women&#41; of sufficient magnitude to cause an increase in the individual&#39;s morbidity and mortality &#40;loss of 3&#8211;10 life-years in the most severe cases<a class="elsevierStyleCrossRef" href="#bib0170"><span class="elsevierStyleSup">4</span></a>&#41;&#44; due to its role in the development of other comorbidities such as arterial hypertension &#40;AHT&#41;&#44; type 2 diabetes mellitus &#40;DM2&#41; and dyslipidemia&#44;<a class="elsevierStyleCrossRefs" href="#bib0175"><span class="elsevierStyleSup">5&#44;6</span></a> as well as severe functional limitations in the quality of life&#46; Therefore&#44; classifying obesity solely on anthropometric measures has numerous limitations and marked variability&#44;<a class="elsevierStyleCrossRef" href="#bib0185"><span class="elsevierStyleSup">7</span></a> because individuals with the same body weight can have various health problems that affect their vital prognosis&#46; BMI is also a poor predictor of mortality&#44; especially in the patients treated in departments of internal medicine &#40;IM&#41; who are older and have more comorbidity&#46; The Edmonton Obesity Staging System &#40;EOSS&#41; provides an obesity classification system that is independent of BMI&#44;<a class="elsevierStyleCrossRef" href="#bib0190"><span class="elsevierStyleSup">8</span></a> incorporating the presence and severity of comorbidities&#44; the gradation of functional limitations and their impact on the quality of life of patients with obesity&#46; The EOSS is therefore more useful in clinical terms for making therapeutic decisions&#46;<a class="elsevierStyleCrossRef" href="#bib0195"><span class="elsevierStyleSup">9</span></a> The EOSS is also a possible predictor of mortality&#44;<a class="elsevierStyleCrossRef" href="#bib0200"><span class="elsevierStyleSup">10</span></a> even after adjusting for other adiposity assessment methods such as abdominal circumference&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">The aim of this study was to determine the prevalence of obesity and classify it according to the Edmonton stages in patients treated at IM departments&#46; The secondary objective was to analyze the clinical&#8211;epidemiological characteristics of the participants with obesity stratified according to EOSS&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0070">Material and methods</span><p id="par0020" class="elsevierStylePara elsevierViewall">An observational&#44; descriptive cross-sectional study was conducted to assess the prevalence of obesity and its classification according to the EOSS in patients treated in outpatient IM clinics&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">The EOSS classification defines the following stages&#58; &#40;a&#41; stage 0&#58; no risk factors &#40;blood pressure&#44; lipid and baseline glucose levels within normal ranges&#41;&#44; no psychopathology&#44; physical symptoms&#44; functional limitation or impairment in wellbeing related to obesity&#59; &#40;b&#41; stage 1&#58; the presence of obesity-related subclinical risk factors &#40;pre-AHT&#44; abnormal baseline glucose levels&#44; high hepatic enzyme levels&#41;&#44; mild physical symptoms &#40;moderate effort dyspnea&#44; fatigue and occasional joint pain&#41;&#44; mild psychopathology&#44; functional limitation or mildly impaired wellbeing&#59; &#40;c&#41; stage 2&#58; presence of established chronic obesity-related diseases &#40;AHT&#44; DM2&#44; obstructive sleep apnea syndrome&#44; osteoarthritis&#41;&#44; moderate limitation in daily life activities and moderately impaired wellbeing&#59; &#40;d&#41; stage 3&#58; established organ damage &#40;acute myocardial infarction&#44; heart failure&#44; stroke&#44; diabetic complications&#41; significant psychopathology &#40;severe depression&#44; suicidal ideation&#41;&#44; functional limitation or significantly impaired wellbeing&#59; and &#40;e&#41; stage 4&#58; chronic obesity-related diseases with severe dysfunction &#40;potentially terminal damage&#41;&#44; psychopathology&#44; functional limitation or severely impaired wellbeing&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">We conducted a study in 38 national centers&#46; The participating centers conducted a 1-day cross-section between the 1st and 14th of February&#44; 2016&#44; to consecutively select patients&#46; The data were collected in an electronic and anonymous registry&#46; We followed the ethical principles of human research as laid out in the Declaration of Helsinki&#44; updated in the General Assembly of Brazil &#40;2013&#41;&#46; We respected the confidentiality and secrecy of personal information according to the Data Protection Law of 15&#47;1999 &#40;BOE 1999&#44; no&#46; 289&#41;&#46; The study was approved by the Clinical Research Ethics Committee of the University Hospital of Badajoz&#46;</p><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0075">Patients</span><p id="par0035" class="elsevierStylePara elsevierViewall">The study included patients who met the following inclusion criteria&#58; BMI<span class="elsevierStyleHsp" style=""></span>&#62;30<span class="elsevierStyleHsp" style=""></span>kg&#47;m<span class="elsevierStyleSup">2</span> and older than 18 years&#46; The study excluded patients who refused to sign the informed consent document&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0080">Variables</span><p id="par0040" class="elsevierStylePara elsevierViewall">The primary endpoint was the categories established by EOSS&#46;<a class="elsevierStyleCrossRef" href="#bib0190"><span class="elsevierStyleSup">8</span></a> Obesity classification by BMI was conducted according to the consensus of the Spanish Society for the Study of Obesity&#46;<a class="elsevierStyleCrossRef" href="#bib0165"><span class="elsevierStyleSup">3</span></a> We obtained demographic&#44; clinicians&#44; anthropometric and laboratory data from the included patients&#46; In terms of the demographic variables&#44; we determined the following&#58; educational level &#40;no studies&#44; basic studies&#44; secondary&#47;professional training and university&#41;&#44; employment status active or not&#44; rural &#40;fewer than 10&#44;000 inhabitants&#41; or urban origin &#40;more than 10&#44;000 inhabitants&#41; and marital status &#40;single or living with a partner&#41;&#46; Lastly&#44; we considered that the patients engaged in physical exercise if they performed more than 30<span class="elsevierStyleHsp" style=""></span>min of aerobic exercise more than 5 days&#47;week&#46; As clinical variables&#44; we included active smoking and excessive alcohol consumption &#40;intake<span class="elsevierStyleHsp" style=""></span>&#62;60<span class="elsevierStyleHsp" style=""></span>g&#47;day in men and<span class="elsevierStyleHsp" style=""></span>&#62;40<span class="elsevierStyleHsp" style=""></span>g&#47;day in women&#41;&#46; We also recorded the previous presence of chronic obstructive pulmonary disease &#40;COPD&#41;&#44; asthma and active cancer &#40;excluding skin cancer&#44; except for melanoma&#41;&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">To calculate comorbidity&#44; we employed the Charlson index<a class="elsevierStyleCrossRef" href="#bib0205"><span class="elsevierStyleSup">11</span></a> &#40;absence of comorbidity&#44; 0&#8211;1&#59; low comorbidity&#44; 2&#59; high comorbidity&#44; &#8805;3&#41;&#46; To measure functional capacity&#44; we used the Barthel index<a class="elsevierStyleCrossRef" href="#bib0210"><span class="elsevierStyleSup">12</span></a> &#40;total dependence&#44; 0&#8211;20 points&#59; severe dependence&#44; 21&#8211;60 points&#59; moderate dependence&#44; 61&#8211;90 points&#59; low dependence&#44; 91&#8211;99 points&#59; independence&#44; 100 points&#41;&#46; For depression&#44; we employed Beck&#39;s scale<a class="elsevierStyleCrossRef" href="#bib0215"><span class="elsevierStyleSup">13</span></a> &#40;0&#8211;9 points&#44; no depression&#59; 10&#8211;15&#44; mild depression&#59; 16&#8211;24 points&#44; moderate depression&#59; and 25&#8211;62 points&#44; severe depression&#41;&#46;</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0085">Statistical analysis</span><p id="par0050" class="elsevierStylePara elsevierViewall">Assuming an expected prevalence of obesity of 23&#37;&#44;<a class="elsevierStyleCrossRef" href="#bib0160"><span class="elsevierStyleSup">2</span></a> a 2&#37; error and a 95&#37; confidence interval&#44; the calculated minimum sample size was 250 patients&#46;</p><p id="par0055" class="elsevierStylePara elsevierViewall">To calculate the prevalence&#44; we used the total number of patients who met the inclusion criteria&#44; analyzing the variables grouped according to EOSS&#46; The qualitative variables are expressed as the total number and percentage referring to EOSS&#46; To compare the variables&#44; we employed the Chi-squared test&#46; The quantitative variables are expressed as median and interquartile range&#46; To comparing the variables&#44; we employed the Kruskal&#8211;Wallis test&#46; We performed a two-dimensional analysis of correspondence to observe significant groupings among the qualitative variables&#44; determining coordinates that allow the representation of classes of the study variables&#46; In the first model&#44; we used the EOSS groups&#44; employment status&#44; education level&#44; Charlson index and Barthel index as the variables&#46; In the second model&#44; we substituted the EOSS groups by BMI&#44; according to the Spanish Society for the Study of Obesity criteria&#46;<a class="elsevierStyleCrossRef" href="#bib0165"><span class="elsevierStyleSup">3</span></a> To determine the coordinates&#44; we used the Chi-squared distance&#46; Finally&#44; we performed a multivariate logistic regression analysis to observe the dependence among the variables&#46; The dependent variable was belonging or not an EOSS group &#8805;2&#46; For the model&#44; we chose the covariates considered significant &#8220;a priori&#8221;&#44; based on previous studies on patients with obesity&#46; We also chose those covariates that dictated the clinical experience&#44; as well as those that were significant in the univariate analysis&#46; In the final model&#44; we analyzed age&#44; BMI&#44; Charlson index&#44; creatinine clearance &#40;Chronic Kidney Disease Epidemiology Collaboration&#44; CKD-EPI&#41;&#44; glucose&#44; uric acid&#44; total cholesterol&#44; leukocytes and albumin&#47;creatinine ratio&#46; We employed the R program &#40;version 3&#46;2&#46;4&#44; Free Software Foundation&#39;s&#44; GNU General Public License&#41;&#46; Differences with a <span class="elsevierStyleItalic">p</span>-value &#60;&#46;05 were considered significant&#46;</p></span></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0090">Results</span><p id="par0060" class="elsevierStylePara elsevierViewall">From a total of 1262 patients treated in consultations&#44; we initially included 298 patients with obesity&#44; 33 of whom were later excluded due to lack of data or consent to use the data&#46; Ultimately&#44; we analyzed 265 patients with obesity &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#44; 135 of whom were men&#46; The mean age &#40;&#177;SD&#41; was 62&#46;47<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>15&#46;27 years&#44; and the BMI &#40;&#177;SD&#41; was 36&#46;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>5&#46;3<span class="elsevierStyleHsp" style=""></span>kg&#47;m<span class="elsevierStyleSup">2</span>&#46; The prevalence of obesity by BMI was 23&#46;62&#37;&#46; By EOSS stages 0&#44; 1&#44; 2&#44; 3 and 4&#44; the prevalence was 4&#46;9&#37;&#44; 14&#46;7&#37;&#44; 62&#46;3&#37;&#44; 15&#46;5&#37; and 2&#46;64&#37;&#44; respectively&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0065" class="elsevierStylePara elsevierViewall"><a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a> lists the patients&#8217; clinical and demographic characteristics according to the EOSS&#46; For the patients with EOSS 2&#44; 3 and 4&#44; we observed a significant increase in age &#40;<span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#46;0000&#41;&#44; DM2 &#40;<span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#46;0001&#41;&#44; dyslipidemia &#40;<span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#46;0003&#41;&#44; obstructive sleep apnea syndrome &#40;<span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#46;0027&#41; and heart failure &#40;p&#60;&#46;0001&#41;&#44; which determined a significant increase in the Charlson index by group &#40;<span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#46;0000&#41;&#46; In the laboratory variables &#40;<a class="elsevierStyleCrossRef" href="#sec0050">Table 1 available in the supplementary material of the online version of this article</a>&#41;&#44; we observed an increase in glucose levels &#40;<span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#46;0003&#41;&#44; leukocyte counts &#40;<span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#46;0000&#41;&#44; uric acid levels &#40;<span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#46;02&#41; and urea levels &#40;<span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#46;004&#41;&#44; as well as a reduction in the glomerular filtration rate &#40;<span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#46;02&#41; in the upper EOSS categories&#46; We observed significant differences in all drug groups employed&#44; except for the sulfonylureas&#44; nonsteroidal anti-inflammatory drugs&#44; antidepressants and anxiolytic agents&#44; which were used equally by all EOSS groups &#40;<a class="elsevierStyleCrossRef" href="#sec0050">Table 2&#44; available in the supplementary material of the online version of this article</a>&#41;&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><p id="par0070" class="elsevierStylePara elsevierViewall">In terms of the analysis of correspondence &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41;&#44; in the first model with a cumulative explanatory percentage of 78&#46;2&#37;&#44; we observed a first patient group clustered around EOSS 0 and 1&#44; with secondary or university education&#44; who were employed&#44; and who had no dependence or comorbidity&#46; We observed another group around EOSS 2&#44; with basic or no education&#44; who were unemployed&#44; who had little dependence and low comorbidity&#46; We also observed a third group around EOSS 3 with moderate or severe dependence and high comorbidity&#44; with no relation to education level or employment status&#46; Finally&#44; we observed an EOSS 4 group with no association with any of the prior conditions&#46; In the second model &#40;replacing EOSS with BMI&#41; with a lower cumulative explanatory percentage &#40;70&#46;6&#37;&#41;&#44; there were no clusters as defined as in the first model&#46; Type 2 and 4 obesity showed no grouping&#46; Type 1 could be grouped with independent patients with no comorbidity&#44; and type 3 could be grouped with unemployed patients with basic or no education&#46;</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0075" class="elsevierStylePara elsevierViewall">In the logistic regression model &#40;<a class="elsevierStyleCrossRef" href="#tbl0010">Table 2</a>&#41;&#44; the variables that ultimately were related with an EOSS stage &#8805;2 were BMI &#40;odds ratio &#91;OR&#93;&#44; 1&#46;07&#59; 95&#37; CI 0&#46;99&#8211;1&#46;16&#59; <span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#46;06&#41;&#44; age &#40;OR&#44; 1&#46;06&#59; 95&#37; CI 1&#46;03&#8211;1&#46;08&#59; <span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#46;0003&#41;&#44; glucose levels &#40;OR 1&#46;04&#44; 95&#37; CI 1&#46;01&#8211;1&#46;07&#59; <span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#46;0006&#41;&#44; total cholesterol levels &#40;OR&#44; 0&#46;98&#59; 95&#37; CI 0&#46;97&#8211;0&#46;99&#59; <span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#46;2&#41; and uric acid levels &#40;OR&#44; 1&#46;32&#59; 95&#37; CI 1&#46;03&#8211;1&#46;68&#59; <span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#46;02&#41;&#46;</p><elsevierMultimedia ident="tbl0010"></elsevierMultimedia></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0095">Discussion</span><p id="par0080" class="elsevierStylePara elsevierViewall">In this study&#44; the prevalence of obesity in the IM consultations was similar to that found in other epidemiological studies in the general population such as the Nutrition and Cardiovascular Risk in Spain &#40;ENRICA&#41; study &#40;23&#37;&#41;<a class="elsevierStyleCrossRef" href="#bib0220"><span class="elsevierStyleSup">14</span></a> and the Spanish Cardiovascular Risk Equation &#40;ERICE&#41;<a class="elsevierStyleCrossRef" href="#bib0225"><span class="elsevierStyleSup">15</span></a> study &#40;22&#46;7&#37;&#41;&#44; both of which had a mean BMI of 26&#46;9&#46;<a class="elsevierStyleCrossRef" href="#bib0230"><span class="elsevierStyleSup">16</span></a> This prevalence increases with age&#44; reaching 35&#37; between 65 and 70 years of age&#46;<a class="elsevierStyleCrossRefs" href="#bib0235"><span class="elsevierStyleSup">17&#44;18</span></a> In our study&#44; most of the patients were included in the age range between 60 and 80 years&#46; A relationship was shown between a higher EOSS &#40;mainly 2 and 3&#41;&#44; a progressive reduction in height&#44; weight and&#44; less significantly&#44; BMI &#40;<span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#46;28&#41; with increasing age &#40;<a class="elsevierStyleCrossRef" href="#tbl0015">Table 3</a>&#41;&#46; The use of BMI to define obesity in the elderly is controversial due to the reduction in height while maintaining a stable weight &#40;reduction estimated at 0&#8211;0&#46;65<span class="elsevierStyleHsp" style=""></span>kg&#47;year&#41;&#44;<a class="elsevierStyleCrossRef" href="#bib0245"><span class="elsevierStyleSup">19</span></a> to the reduction in muscle mass and to the redistribution of adipose deposits in the abdomen and perivisceral area &#40;&#8220;sarcopenic obesity&#8221;&#41;&#46; This increase in adiposity is responsible for mobility-related disability&#44; greater functional impairment&#44; increased cardiovascular risk&#44; arthritis and greater obesity-attributable mortality&#44; estimated at 28&#44;000 deaths annually&#44; even after adjusting for abdominal adiposity&#46;<a class="elsevierStyleCrossRef" href="#bib0250"><span class="elsevierStyleSup">20</span></a> Engelmann et al&#46; and other authors have reported a <span class="elsevierStyleItalic">J</span> curve between BMI and mortality&#46;<a class="elsevierStyleCrossRef" href="#bib0255"><span class="elsevierStyleSup">21</span></a> In contrast&#44; the so-called &#8220;obesity paradox&#8221; reports lower mortality&#44; by cardiovascular<a class="elsevierStyleCrossRef" href="#bib0260"><span class="elsevierStyleSup">22</span></a> and noncardiovascular<a class="elsevierStyleCrossRef" href="#bib0265"><span class="elsevierStyleSup">23</span></a> diseases&#44; in the elderly with obesity&#46; Nevertheless&#44; there are numerous confounding factors&#44; such as the degree of inflammation and renal dysfunction&#44; which can influence this paradox&#46;<a class="elsevierStyleCrossRef" href="#bib0270"><span class="elsevierStyleSup">24</span></a></p><elsevierMultimedia ident="tbl0015"></elsevierMultimedia><p id="par0085" class="elsevierStylePara elsevierViewall">Eighty percent of the patients in this study had an EOSS stage &#8805;2&#44; which was associated with greater age and functional impairment and more comorbidity &#40;<a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a>&#41;&#46; Most studies on the prevalence of obesity have been based on the BMI and age&#44; while there are few references to comorbidity<a class="elsevierStyleCrossRefs" href="#bib0275"><span class="elsevierStyleSup">25&#44;26</span></a> and functional capacity&#46; It is therefore difficult in this context to recognize obesity as a complex chronic condition and&#44; accordingly&#44; address it from a comprehensive perspective based not only on anthropometric measures but also on the treatment of the complications related to weight and adiposity&#44; with the ultimate objective of improving health and overall quality of life&#46;<a class="elsevierStyleCrossRefs" href="#bib0285"><span class="elsevierStyleSup">27&#44;28</span></a></p><p id="par0090" class="elsevierStylePara elsevierViewall">As shown by the analysis of correspondence &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41;&#44; the EOSS can discriminate those patients with greater comorbidity and lower functional capacity&#44; facilitating a comprehensive approach to the problem and can do so better than the BMI&#46; The few published studies based on EOSS agree on its role as a predictor of mortality<a class="elsevierStyleCrossRef" href="#bib0200"><span class="elsevierStyleSup">10</span></a> and its usefulness for prioritizing treatments such as bariatric surgery&#46;<a class="elsevierStyleCrossRef" href="#bib0295"><span class="elsevierStyleSup">29</span></a> This is the first national study of the prevalence of obesity in patients in standard clinical practice classified according to the associated comorbidities&#46;</p><p id="par0095" class="elsevierStylePara elsevierViewall">Moreover&#44; in the adjusted multivariate analysis&#44; we observed a direct association between an EOSS stage &#62;2 and a number of metabolic traits such as blood glucose &#40;OR&#44; 1&#46;04&#59; <span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#46;0006&#41; and uric acid &#40;OR&#44; 1&#46;32&#59; <span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#46;02&#41; levels&#46; An inverse association was observed with serum cholesterol levels &#40;OR&#44; 0&#46;98&#59; <span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#46;02&#41;&#44; which was possibly due to the increased use of statins in the groups with higher EOSS stages &#40;see <a class="elsevierStyleCrossRef" href="#sec0050">supplementary material available in the online version</a>&#41;&#46; Obesity is the main modifiable risk factor for the onset of hyperuricemia and gout&#46; The relationship between hyperuricemia and cardiovascular disease is controversial and not uniform between the sexes&#46; Marotta et al&#46;&#44; in one of the few studies on elderly patients&#44; found a linear relationship between uric acid levels higher than 5&#46;5<span class="elsevierStyleHsp" style=""></span>mg&#47;dL and the onset of obesity&#44; AHT and DM2 in women older than 60 years&#46;<a class="elsevierStyleCrossRef" href="#bib0300"><span class="elsevierStyleSup">30</span></a></p><p id="par0100" class="elsevierStylePara elsevierViewall">This study had some limitations&#46; The treated population and the type of IM consultations were highly heterogeneous&#44; which could have resulted in a patient selection bias&#46; However&#44; we can consider the patients as representative of the general adult population&#46; Although the sample may seem small&#44; it is consistent with the initially estimated size&#44; considering that the design was cross-sectional &#40;only 1 day within the inclusion period&#41;&#46; Moreover&#44; this design does not let us establish casual relationships between the variables&#46; The described associations should therefore be subsequently evaluated&#46;</p><p id="par0105" class="elsevierStylePara elsevierViewall">In conclusion&#44; the prevalence of obesity among the patients treated in the IM consultations is similar to that described for the general population&#46; However&#44; the patients treated in IM departments are older&#44; have higher BMIs and greater comorbidity&#44; both metabolic and functional&#46; EOSS is useful for conducting a comprehensive approach for patients with obesity&#44; regardless of BMI&#44; which can help achieve better health and quality-of-life results&#46;</p></span><span id="sec0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0100">Conflicts of interest</span><p id="par0110" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflicts of interest with this article&#46;</p></span></span>"
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          "titulo" => "Background"
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              "titulo" => "Patients"
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              "titulo" => "Variables"
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          "identificador" => "sec0040"
          "titulo" => "Conflicts of interest"
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          "titulo" => "References"
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    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2016-07-20"
    "fechaAceptado" => "2016-11-03"
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          "clase" => "keyword"
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          "palabras" => array:4 [
            0 => "Obesity"
            1 => "Edmonton"
            2 => "Prevalence"
            3 => "Comorbidities"
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          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec804159"
          "palabras" => array:4 [
            0 => "Obesidad"
            1 => "Edmonton"
            2 => "Prevalencia"
            3 => "Comorbilidades"
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    "resumen" => array:2 [
      "en" => array:3 [
        "titulo" => "Abstract"
        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Objectives</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">To estimate the prevalence of obesity in patients treated by departments of Internal Medicine and to classify the patients according to the Edmonton Obesity Staging System &#40;EOSS&#41;&#46;</p></span> <span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Material and methods</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">An observational&#44; descriptive cross-sectional study included outpatients older than 18 years&#44; with a body mass index &#40;BMI&#41;<span class="elsevierStyleHsp" style=""></span>&#62;<span class="elsevierStyleHsp" style=""></span>30&#44; from 38 hospitals between the 1st and 14th of February&#44; 2016&#46; We classified the patients according to the EOSS and analyzed their clinical&#44; laboratory and demographic variables&#46; A value of <span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#46;05 was considered statistically significant&#46;</p></span> <span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Results</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Of the 1262 patients treated in consultations&#44; we recruited 298 and analyzed 265&#46; The prevalence of obesity was 23&#46;6&#37;&#44; the mean age was 62&#46;47<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>15&#46;27 years&#44; and the mean BMI was 36&#46;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>5&#46;3<span class="elsevierStyleHsp" style=""></span>kg&#47;m<span class="elsevierStyleSup">2</span>&#46; According to EOSS stage &#40;0&#44; 1&#44; 2&#44; 3 and 4&#41;&#44; the prevalence was 4&#46;9&#44; 14&#46;7&#44; 62&#46;3&#44; 15&#46;5 and 2&#46;64&#37;&#44; respectively&#46; Those patients with EOSS<span class="elsevierStyleHsp" style=""></span>&#62;<span class="elsevierStyleHsp" style=""></span>2 were significantly older and had significantly more comorbidities&#46; The multivariate analysis related age &#40;OR 1&#46;06&#59; <span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#46;0003&#41;&#44; blood glucose &#40;OR 1&#46;04&#59; <span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#46;0006&#41;&#44; total cholesterol &#40;OR 0&#46;98&#59; <span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#46;02&#41; and uric acid &#40;OR 1&#46;32&#59; <span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#46;02&#41; levels with an EOSS<span class="elsevierStyleHsp" style=""></span>&#62;<span class="elsevierStyleHsp" style=""></span>2&#46; An analysis of correspondence grouped&#44; with an explanatory percentage of 78&#46;2&#37;&#44; the patients according to their EOSS&#44; comorbidity&#44; education level&#44; employment status and functional capacity&#46;</p></span> <span id="abst0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Conclusions</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">The prevalence of obesity in the patients treated by Internal Medicine departments is similar to that of the general population&#44; although the patients are older and have a higher BMI&#46; EOSS is useful for implementing a comprehensive approach for patients with obesity&#44; regardless of the BMI&#44; which can help achieve better health and quality-of-life results&#46;</p></span>"
        "secciones" => array:4 [
          0 => array:2 [
            "identificador" => "abst0005"
            "titulo" => "Objectives"
          ]
          1 => array:2 [
            "identificador" => "abst0010"
            "titulo" => "Material and methods"
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          2 => array:2 [
            "identificador" => "abst0015"
            "titulo" => "Results"
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          3 => array:2 [
            "identificador" => "abst0020"
            "titulo" => "Conclusions"
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        "titulo" => "Resumen"
        "resumen" => "<span id="abst0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Objetivos</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Estimar la prevalencia de obesidad y clasificarla seg&#250;n la estadificaci&#243;n de Edmonton &#40;EOSS&#41; en pacientes atendidos por Medicina Interna&#46;</p></span> <span id="abst0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Material y m&#233;todos</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Estudio observacional&#44; descriptivo y transversal&#46; Incluy&#243; pacientes ambulatorios mayores de 18 a&#241;os con un &#237;ndice de masa corporal &#40;IMC&#41; &#62; 30&#44; procedentes de 38 hospitales&#44; entre el 1 y el 14 de febrero de 2016&#46; Se clasificaron seg&#250;n EOSS y se analizaron variables cl&#237;nicas&#44; anal&#237;ticas y sociodemogr&#225;ficas&#46; Se consider&#243; significaci&#243;n estad&#237;stica con p &#60; 0&#44;05&#46;</p></span> <span id="abst0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Resultados</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">De 1&#46;262 pacientes vistos en las consultas se seleccionaron 298 y se analizaron 265&#46; La prevalencia de obesidad fue del 23&#44;6&#37;&#44; la edad&#44; de 62&#44;47 &#177; 15&#44;27 a&#241;os y el IMC&#44; de 36&#44;1 &#177; 5&#44;3 kg&#47;m<span class="elsevierStyleSup">2</span>&#46; Por EOSS &#40;0&#44; 1&#44; 2&#44; 3 y 4&#41; la prevalencia fue de 4&#44;9&#44; 14&#44;7&#44; 62&#44;3&#44; 15&#44;5 y 2&#44;64&#37;&#44; respectivamente&#46;&#160;Aquellos pacientes con EOSS &#62; 2 ten&#237;an significativamente m&#225;s edad y comorbilidades&#46; El an&#225;lisis multivariante relacion&#243; la edad &#40;OR 1&#44;06&#44; p &#60; 0&#44;0003&#41;&#44; la glucemia &#40;OR 1&#44;04&#44; p &#60; 0&#44;0006&#41;&#44; el colesterol total &#40;OR 0&#44;98&#44; p &#60; 0&#44;02&#41; y el &#225;cido &#250;rico &#40;OR 1&#44;32&#44; p &#60; 0&#44;02&#41; con un EOSS &#62; 2&#46; Un an&#225;lisis de correspondencias agrup&#243;&#44; con un porcentaje explicativo del 78&#44;2&#37;&#44; a los pacientes seg&#250;n su EOSS&#44; comorbilidad&#44; nivel de estudios&#44; situaci&#243;n laboral y capacidad funcional&#46;</p></span> <span id="abst0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Conclusiones</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">La prevalencia de obesidad en pacientes atendidos por Medicina Interna es similar a la de la poblaci&#243;n general&#44; aunque los pacientes son de mayor edad e IMC&#46; El EOSS es &#250;til para hacer una aproximaci&#243;n integral de los pacientes obesos&#44; independientemente del IMC&#44; lo que puede posibilitar la obtenci&#243;n de mejores resultados en salud y en calidad de vida&#46;</p></span>"
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            "titulo" => "Material y m&#233;todos"
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            "titulo" => "Resultados"
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            "titulo" => "Conclusiones"
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    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; Carretero G&#243;mez J&#44; Ar&#233;valo Lorido JC&#44; G&#243;mez Huelgas R&#44; S&#225;nchez Vidal MT&#44; Su&#225;rez Tembra M&#44; Varela Aguilar JM&#44; et al&#46; Prevalencia de obesidad seg&#250;n la estadificaci&#243;n de Edmonton en las consultas de Medicina Interna&#46; Resultados del estudio OBEMI&#46; Rev Clin Esp&#46; 2017&#59;217&#58;71&#8211;78&#46;</p>"
      ]
    ]
    "apendice" => array:1 [
      0 => array:1 [
        "seccion" => array:2 [
          0 => array:4 [
            "apendice" => "<p id="par0125" class="elsevierStylePara elsevierViewall">Alonso Pe&#241;a&#44; Javier&#46; Hospital Virgen del Puerto&#46; Plasencia&#46; Ar&#233;valo Lorido&#44; Jos&#233; Carlos&#46; Regional Hospital of Zafra&#46; Badajoz&#46; Arg&#252;ello Mart&#237;n&#44; Carlota&#46; Central Hospital of Asturias&#46; Bonilla Hern&#225;ndez&#44; Mar&#237;a&#46; Hospital Reina Sof&#237;a&#46; Tudela&#46; Campo L&#243;pez Cristina&#46; Hospital La Fe&#46; Valencia&#46; Carabantes Rueda&#44; Juan Jes&#250;s&#46; Hospital of Antequera&#44; Antequera&#46; Carretero G&#243;mez&#44; Juana&#46; Regional Hospital of Zafra&#46; Badajoz&#46; Castiella Herrero&#44; Jes&#250;s&#46; Foundation Hospital of Calahorra&#44; Calahorra&#44; La Rioja&#46; Chimeno Vi&#241;as&#44; Mar&#237;a Montserrat&#46; Healthcare Complex of Zamora&#46; De Escalante Yang&#252;ela&#44; Bego&#241;a&#46; Clinic Hospital Zaragoza&#46; Due&#241;as Gutierrez&#44; Carlos&#46; Hospital of Burgos&#46; Ena Mu&#241;oz&#44; Javier&#46; Hospital of la Marina Baixa&#46; Alicante&#46; Fern&#225;ndez Rodr&#237;guez&#44; Jos&#233; Mar&#237;a&#46; Hospital Carmen y Severo Ochoa&#46; Cangas de Narcea&#46; Asturias&#46; Fern&#225;ndez P&#233;rez&#44; Ester&#46; Hospital of Le&#243;n&#46; Freixas Descarregas&#44; Pere&#46; Regional Hospital Mor&#225; d&#201;bre&#46; Tarragona&#46; Garc&#237;a Contreras&#44; Rosa&#46; Hospital Virgen del Roc&#237;o&#46; Seville&#46; Garc&#237;a Ledesma&#44; Luis&#46; Hospital Virgen del Puerto&#44; Plasencia&#46; Garc&#237;a Ordo&#241;ez&#44; Miguel &#193;ngel&#44; Hospital of Antequera&#44; Antequera&#46; Gonz&#225;lez Aguirre&#44; Jos&#233; Manuel&#46; Hospital la Mancha Centro&#44; Alc&#225;zar de San Juan&#44; Ciudad Real&#46; Gonz&#225;lez Hern&#225;ndez&#44; Carmen&#46; Hospital G&#243;mez Ulla&#46; Madrid&#46; Gonz&#225;lez Sarmiento&#44; Enrique&#46; Clinic Hospital&#46; Valladolid&#46; Gracia Tello&#44; Borja&#46; Clinic Hospital of Zaragoza&#46; Hurtado&#44; Roberto&#46; Hospital of la Vega Baja&#46; Alicante&#46; Inglada Galiana&#44; Luis&#46; Hospital R&#237;o Hortega&#46; Valladolid&#46; Ja&#233;n &#193;guila&#44; Fernando&#46; University Hospital Complex of Granada&#46; Jim&#233;nez Hidalgo&#44; Alicia&#46; Hospital Juan Ram&#243;n Jim&#233;nez&#46; Huelva&#46; Lacal Mart&#237;nez&#44; Ana&#46; Hospital of Vendrell&#46; Tarragona&#46; L&#243;pez Carmona&#44; Mar&#237;a Dolores&#46; Hospital Carlos Haya&#46; Malaga&#46; Lucena Calvet&#44; Paloma&#46; Hospital G&#243;mez Ulla&#46; Madrid&#46; Maci&#225; Botejara&#44; Enrique&#46; Hospital Perpet&#250;o Socorro&#46; Badajoz&#46; Mateos Polo&#44; Lourdes&#44; University Hospital of Salamanca&#46; Mediavilla Garc&#237;a&#44; Juan Diego&#46; University Hospital Complex of Granada&#46; Mej&#237;as&#44; Inma&#46; Hospital of Cabra&#46; M&#233;ndez Bail&#243;n&#44; Manuel&#46; Clinic Hospital San Carlos&#46; Madrid&#46; Mich&#225;n Do&#241;a&#44; Alfredo&#46; Hospital of Jerez&#44; Jerez de la Frontera&#44; Cadiz&#46; Moya Mateo&#44; Eva&#46; Hospital Infanta Leonor&#46; Madrid&#46; Munielo Voces&#44; Isabel&#46; Hospital of Le&#243;n&#46; Mu&#241;oz L&#243;pez&#44; Juan Jos&#233;&#46; High-resolution Hospital Utrera&#46; Mu&#241;oz Rivas&#44; Nuria&#46; Hospital Infanta Leonor&#44; Madrid&#46; Naranjo Velasco&#44; Virginia&#46; Hospital of Jerez&#44; Jerez de la Frontera&#44; Cadiz&#46; Nobilia Gigena&#44; Laura&#46; Hospital of Vendrell&#46; Tarragona&#46; P&#233;rez Bernalte&#44; Rosa&#46; Hospital of Vendrell&#46; Tarragona&#46; P&#233;rez Soto&#44; Mar&#237;a Isabel&#46; Hospital of Vinalopo&#46; Elche&#46; Puchades&#44; Francesc&#46; Hospital Pare Jofr&#233; and Hospital Casa Salud&#46; Valencia&#46; S&#225;nchez Lora&#44; Javier&#46; Hospital Virgen de la Victoria&#46; Malaga&#46; S&#225;nchez Vidal&#44; Mar&#237;a Teresa&#46; Foundation Hospital of Jov&#233;&#46; Gij&#243;n&#46; Su&#225;rez Tembra&#44; Manuel&#46; Hospital San Rafael&#46; A Coru&#241;a&#46; Toro Parodo&#44; Aythami&#46; Hospital of Ceuta&#44; Ceuta&#46; Varela Aguilar&#44; Jos&#233; Manuel&#46; Epidemiology and Public Health CIBER&#46; Hospital Virgen del Roc&#237;o&#46; Seville&#46; Vigueras P&#233;rez&#44; Juan Francisco&#46; Hospital Santa Catalina&#46; Las Palmas&#46; Zamb&#243;n Rad&#243;s&#44; Daniel&#46; Hospital Clinic&#46; Barcelona&#46;</p>"
            "etiqueta" => "Appendix A"
            "titulo" => "OBEMI Registry Participants"
            "identificador" => "sec0045"
          ]
          1 => array:4 [
            "apendice" => "<p id="par0135" class="elsevierStylePara elsevierViewall">The following are the supplementary data to this article&#58;<elsevierMultimedia ident="upi0005"></elsevierMultimedia></p>"
            "etiqueta" => "Appendix B"
            "titulo" => "Supplementary data"
            "identificador" => "sec0055"
          ]
        ]
      ]
    ]
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      0 => array:7 [
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        "etiqueta" => "Figure 1"
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          0 => array:4 [
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        "descripcion" => array:1 [
          "en" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Study flow diagram&#46; BMI&#44; body mass index&#59; EOS&#44; Edmonton Obesity Staging System&#46;</p>"
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        "etiqueta" => "Figure 2"
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          "en" => "<p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">Analysis of correspondence&#46; Upper part has the analysis with the Edmonton groups&#46; The lower part has the analysis with the obesity classification according to the body mass index&#46; BI&#44; Barthel Index&#59; BMI&#44; body mass index&#59; CI&#44; Charlson index&#59; EOSS&#44; Edmonton Obesity Staging System&#59; Stds&#44; studies&#46;</p>"
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          "leyenda" => "<p id="spar0060" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleItalic">Abbreviations</span>&#58; AHT&#44; systemic arterial hypertension&#59; COPD&#44; chronic obstructive pulmonary disease&#59; DM&#44; diabetes mellitus&#59; EOSS&#44; Edmonton Obesity Staging System&#59; GERD&#44; gastroesophageal reflux disease&#59; OSAHS&#44; obstructive sleep apnea&#47;hypopnea syndrome&#46;</p><p id="spar0065" class="elsevierStyleSimplePara elsevierViewall">The quantitative variables are expressed as median &#40;interquartile range&#41;&#46; The qualitative variables are expressed as absolute numbers &#40;percentage&#41;&#46;</p>"
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                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">EOSS 1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">EOSS 2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">EOSS 3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">EOSS 4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black"><span class="elsevierStyleItalic">p</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">N</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">13&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">39&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">165&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">41&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Age&#44; y</span>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">50&#46;33 &#40;16&#46;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">64&#46;95 &#40;14&#46;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">65&#46;27 &#40;10&#46;3&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#46;0000&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Sex&#44; m</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6 &#40;46&#46;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">22 &#40;56&#46;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">84 &#40;50&#46;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">20 &#40;48&#46;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3 &#40;42&#46;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#46;93&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Weight&#44; kg</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">88&#46;9 &#40;73&#46;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">92&#46;9 &#40;69&#46;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">92 &#40;94&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">96&#46;9 &#40;86&#46;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">87 &#40;43&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#46;58&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">BMI&#44; kg&#47;m</span><span class="elsevierStyleSup"><span class="elsevierStyleItalic">2</span></span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">33&#46;59 &#40;20&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">34&#46;25 &#40;21&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">34&#46;76 &#40;25&#46;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">35&#46;56 &#40;28&#46;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">32&#46;23 &#40;14&#46;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#46;25&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Abdominal circumference&#44; cm</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">114&#46;46 &#40;14&#46;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">110&#46;97 &#40;11&#46;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">115&#46;64 &#40;13&#46;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">117&#46;23 &#40;12&#46;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">114&#46;57 &#40;16&#46;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#46;27&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Charlson index</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;11&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3 &#40;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3 &#40;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#46;0000&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Test de Beck Depression Test &#40;n</span><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">&#61;</span><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">259&#41;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5 &#40;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7 &#40;15&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7 &#40;11&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10 &#40;11&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11 &#40;11&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#46;53&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Unemployed</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5 &#40;38&#46;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">17 &#40;43&#46;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">122 &#40;73&#46;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">31 &#40;75&#46;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6 &#40;85&#46;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#46;0003&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="7" align="left" valign="top"><span class="elsevierStyleItalic">Barthel index &#40;degree of dependence&#41;</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Independent &#40;100&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">13 &#40;100&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">35 &#40;89&#46;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">114 &#40;69&#46;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">25 &#40;60&#46;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Mild &#40;91&#8211;99&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;5&#46;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">35 &#40;21&#46;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7 &#40;17&#46;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3 &#40;42&#46;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Moderate &#40;61&#8211;90&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;2&#46;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">12 &#40;7&#46;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7 &#40;17&#46;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3 &#40;42&#46;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Severe &#40;21&#8211;60&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;2&#46;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4 &#40;1&#46;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;4&#46;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;14&#46;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Total &#40;0&#8211;20&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Physical inactivity</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7 &#40;53&#46;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">20 &#40;51&#46;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">112 &#40;67&#46;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">29 &#40;70&#46;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7 &#40;100&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#46;06&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Resident in rural area</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3 &#40;23&#46;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">13 &#40;33&#46;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">58 &#40;35&#46;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">15 &#40;36&#46;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;28&#46;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Smoking</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3&#40;23&#46;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6 &#40;15&#46;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">22 &#40;13&#46;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5 &#40;12&#46;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Alcohol</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;2&#46;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">13 &#40;7&#46;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5 &#40;12&#46;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;14&#46;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#46;77&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">AHT</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">145 &#40;87&#46;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">34 &#40;82&#46;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4 &#40;57&#46;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#46;0001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Type 2 DM</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">86 &#40;52&#46;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">24 &#40;58&#46;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5 &#40;71&#46;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#46;0001&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">19 &#40;48&#46;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">111 &#40;67&#46;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">30 &#40;73&#46;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4 &#40;57&#46;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#46;0003&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">OSAHS</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5 &#40;12&#46;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">42 &#40;25&#46;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">15 &#40;36&#46;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;14&#46;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#46;027&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5 &#40;38&#46;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">8 &#40;20&#46;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">27 &#40;16&#46;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10 &#40;24&#46;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;14&#46;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#46;3&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3 &#40;23&#46;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4 &#40;10&#46;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">22 &#40;13&#46;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6 &#40;14&#46;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3 &#40;42&#46;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#46;19&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Heart failure</span>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;2&#46;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">35 &#40;21&#46;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">17 &#40;41&#46;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4 &#40;57&#46;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#46;0001&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">17 &#40;43&#46;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">52 &#40;31&#46;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">15 &#40;36&#46;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;14&#46;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#46;04&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Ischemic heart disease</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">13 &#40;7&#46;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">18 &#40;43&#46;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#46;0001&nbsp;\t\t\t\t\t\t\n
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          "leyenda" => "<p id="spar0075" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleItalic">Abbreviations</span>&#58; BMI&#44; body mass index&#59; CI&#44; confidence interval&#59; EOSS&#44; Edmonton Obesity Staging System&#59; OR&#44; odds ratio&#46;</p><p id="spar0080" class="elsevierStyleSimplePara elsevierViewall">Logistic regression&#46; The model reflects the variables that independently influence having an EOSS &#8805;2&#46; For the analysis&#44; we included age&#44; sex&#44; body mass index&#44; Charlson index&#44; creatinine clearance&#44; glycemia&#44; total cholesterol&#44; uric acid&#44; leukocyte number and albumin&#47;creatinine ratio&#46;</p>"
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                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">OR&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Uric acid&nbsp;\t\t\t\t\t\t\n
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          "leyenda" => "<p id="spar0090" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleItalic">Abbreviations</span>&#58; BMI&#44; body mass index&#59; EOSS&#44; Edmonton Obesity Staging System&#46;</p><p id="spar0095" class="elsevierStyleSimplePara elsevierViewall">The quantitative variables are expressed as median &#40;interquartile range&#41;&#46; The qualitative variables are expressed as absolute numbers &#40;percentage&#41;&#46;</p>"
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                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Variable&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">41&#8211;50 years&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">29&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">65&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">52&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">68&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">30&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">168 &#40;16&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">168 &#40;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">165 &#40;11&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">160 &#40;13&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">158 &#40;14&#46;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">155&#46;5 &#40;13&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#46;0001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Weight&#44; kg&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">109&#46;4 &#40;43&#46;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">105&#46;15 &#40;35&#46;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">101 &#40;22&#46;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">96&#46;65 &#40;25&#46;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">90&#46;15 &#40;17&#46;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">88&#46;75 &#40;16&#46;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">84&#46;5 &#40;23&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#46;0001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">BMI&#44; kg&#47;m<span class="elsevierStyleSup">2</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">38&#46;99 &#40;9&#46;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">33&#46;05 &#40;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">35&#46;36 &#40;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">34&#46;25 &#40;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">33&#46;42 &#40;7&#46;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">33&#46;34 &#40;4&#46;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">33&#46;9 &#40;3&#46;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#46;28&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">EOSS 0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;20&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;10&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;6&#46;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5 &#40;7&#46;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3 &#40;5&#46;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">EOSS 1&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4 &#40;40&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">8 &#40;27&#46;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">12 &#40;18&#46;5&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4 &#40;5&#46;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">EOSS 2&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5 &#40;50&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">26 &#40;86&#46;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">14 &#40;21&#46;5&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">EOSS 4&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0 &#40;0&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4 &#40;5&#46;9&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
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                      "titulo" => "Factores asociados al padecimiento de obesidad en muestras representativas de la poblaci&#243;n espa&#241;ola"
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                          "etal" => true
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                  "host" => array:1 [
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                    0 => array:1 [
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                      "titulo" => "The potential role of the Edmonton obesity staging system in determining indications for bariatric surgery"
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                    0 => array:2 [
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                    0 => array:2 [
                      "titulo" => "A new method of classifying prognostic comorbidity in longitudinal studies&#58; development and validation"
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Original article
Prevalence of obesity according to Edmonton staging in the Internal Medicine consultations. Results of the OBEMI study
Prevalencia de obesidad según la estadificación de Edmonton en las consultas de Medicina Interna. Resultados del estudio OBEMI
J. Carretero Gómeza,
Corresponding author
juanicarretero@gmail.com

Corresponding author.
, J.C. Arévalo Loridoa, R. Gómez Huelgasb, M.T. Sánchez Vidalc, M. Suárez Tembrad, J.M. Varela Aguilare, I. Munielo Vocesf, E. Fernández Pérezf, J.M. Fernández Rodríguezg, J. Ena Muñozh
a Servicio de Medicina Interna, Hospital Comarcal de Zafra, Zafra, Badajoz, Spain
b Servicio de Medicina Interna, Complejo Hospitalario Universitario de Málaga, Málaga, Spain
c Servicio de Medicina Interna, Fundación Hospital de Jové, Gijón, Asturias, Spain
d Servicio de Medicina Interna, Hospital San Rafael, A Coruña, Spain
e Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERSAM), Hospital Virgen del Rocío, Sevilla, Spain
f Servicio de Medicina Interna, Complejo Asistencial Universitario de León, León, Spain
g Servicio de Medicina Interna, Hospital Carmen y Severo Ochoa, Cangas del Narcea, Asturias, Spain
h Servicio de Medicina Interna, Hospital Marina Baixa, La Vila Joiosa, Alicante, Spain

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