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    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0065">Background</span><p id="par0005" class="elsevierStylePara elsevierViewall">Carbon monoxide &#40;CO&#41; poisoning is a common reason for emergency department visits&#46;<a class="elsevierStyleCrossRefs" href="#bib0100"><span class="elsevierStyleSup">1&#8211;3</span></a> CO is a colorless&#44; odorless and nonirritating gas&#46; Its affinity for hemoglobin is 200-fold greater than that of oxygen and therefore forms carboxyhemoglobin &#40;COHb&#41; even with minor exposure&#46;<a class="elsevierStyleCrossRef" href="#bib0115"><span class="elsevierStyleSup">4</span></a> Exposure to moderate quantities causes headaches&#44; nausea&#44; muscle weakness and dizziness&#44; which can imitate the common cold and is often incorrectly diagnosed&#46;<a class="elsevierStyleCrossRefs" href="#bib0115"><span class="elsevierStyleSup">4&#44;5</span></a> More significant poisonings are potentially severe and can cause confusion&#44; seizures&#44; loss of consciousness and even death&#46;<a class="elsevierStyleCrossRefs" href="#bib0100"><span class="elsevierStyleSup">1&#44;6</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">The measurement of COHb levels is indicated for the diagnosis&#44; although its reliability decreases as the length of time since the exposure increases&#46;<a class="elsevierStyleCrossRef" href="#bib0115"><span class="elsevierStyleSup">4</span></a> The COHb levels depend on numerous factors&#44; such as the magnitude of the exposure&#44; alveolar ventilation&#44; blood volume and metabolic activity&#46; In adults at rest&#44; these levels are mainly influenced by the level of CO in the environment and the duration of exposure&#46;<a class="elsevierStyleCrossRef" href="#bib0115"><span class="elsevierStyleSup">4</span></a> A COHb level greater than 3&#37; in nonsmokers or greater than 10&#37; in smokers confirms CO exposure&#46;<a class="elsevierStyleCrossRef" href="#bib0115"><span class="elsevierStyleSup">4</span></a> However&#44; a number of studies have indicated that COHb levels do not correlate with the presence or absence of initial symptoms or with subsequent sequela&#44; which can be attributed to inflammatory mechanisms triggered by the poisoning more than to the hypoxia itself&#46;<a class="elsevierStyleCrossRef" href="#bib0130"><span class="elsevierStyleSup">7</span></a> Detecting asymptomatic poisoned individuals is unusual given that people are generally only admitted to emergency departments if they have some type of symptom&#46;<a class="elsevierStyleCrossRefs" href="#bib0135"><span class="elsevierStyleSup">8&#44;9</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">The aim of this study was to report a mass CO poisoning that affected a large group of television viewers of a football match and to compare the symptomatic confirmed cases with the asymptomatic ones&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0070">Methods</span><p id="par0020" class="elsevierStylePara elsevierViewall">On February 2&#44; 2015&#44; the epidemiology unit of Lleida was notified that more than 30 individuals from a football group had contacted the emergency department of University Hospital Arnau de Vilanova of Lleida the previous night due to alleged CO poisoning from a butane stove in a social setting&#46; An epidemiological study was designed to report the mass poisoning&#44; the individuals affected and the factors associated with the poisoning and with the presence of clinical symptoms&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">The local government and those responsible for the football group were contacted&#44; and a comprehensive list of the individuals exposed was obtained&#46; A visual inspection of the locale where the exposure took place was conducted&#44; during which the presence of a butane stove for outside use was confirmed&#46; An epidemiological survey of those exposed individuals was conducted&#44; and their medical histories were reviewed&#46; We collected information on epidemiological &#40;time of exposure and distance from the stove&#41;&#44; clinical &#40;history of chronic diseases&#44; toxic habits and symptoms&#41;&#44; laboratory &#40;COHb levels&#41; and treatment &#40;oxygen and hyperbaric chamber&#41; variables&#46; We used the definition of &#8220;confirmed case&#8221; of the Centers for Disease Control &#40;Atlanta&#44; US&#41;&#58; nonsmoker patient with COHb levels &#62;5&#37; or smoker with levels &#62;10&#37;&#46;<a class="elsevierStyleCrossRef" href="#bib0145"><span class="elsevierStyleSup">10</span></a> We also considered as probable cases those patients with compatible symptoms &#40;2 or more of the following symptoms&#58; headache&#44; nausea&#44; weakness&#44; dizziness&#44; disorientation&#44; dyspnea&#44; nervousness or seizures&#41; but with no COHb reading or a reading performed more than 6<span class="elsevierStyleHsp" style=""></span>h after the exposure&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">The attack rate was calculated&#44; and an epidemic curve was prepared&#46; We conducted a bivariate analysis to compare the patients who met the definition of case with the rest of the exposed patients&#46; The cases confirmed by symptoms were also compared to the confirmed asymptomatic cases&#46; The presence of a statistical association was studied with Fisher&#39;s exact test for qualitative variables or the Kruskal&#8211;Wallis nonparametric test when one of them was quantitative&#46; Values of <span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#46;05 were considered significant&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0075">Results</span><p id="par0035" class="elsevierStylePara elsevierViewall">Thirty-nine exposed individuals were studied&#46; Their mean age was 43&#46;8<span class="elsevierStyleHsp" style=""></span>years &#40;SD&#44; 22&#46;1&#41;&#44; and 11 &#40;28&#46;2&#37;&#41; of them were women&#46; Nine &#40;23&#46;1&#37;&#41; individuals had a previous disease or chronic disorder such as arterial hypertension &#40;6&#44; 66&#46;7&#37;&#41;&#44; diabetes &#40;4&#44; 44&#46;4&#37;&#41; or ischemic heart disease &#40;2&#44; 22&#46;2&#37;&#41;&#46; The mean exposure time was 52&#46;4<span class="elsevierStyleHsp" style=""></span>min &#40;SD&#44; 21&#46;0&#41;&#44; and the mean distance from the stove was 4&#46;2<span class="elsevierStyleHsp" style=""></span>m &#40;SD&#44; 2&#46;5&#41;&#46; Most cases &#40;31&#41; were confirmed by measuring COHb in blood&#46; Only 3 of those exposed were considered probable cases due to presenting compatible symptoms but with no reliable COHb reading&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">The attack rate was very high &#40;34&#44; 87&#46;2&#37;&#41;&#46; The patients&#8217; symptoms were headache &#40;50&#37;&#41;&#44; nausea &#40;20&#46;6&#37;&#41;&#44; weakness &#40;20&#46;6&#37;&#41;&#44; dizziness &#40;14&#46;7&#37;&#41;&#44; disorientation &#40;8&#46;8&#37;&#41;&#44; dyspnea &#40;8&#46;8&#37;&#41;&#44; vomiting &#40;2&#46;9&#37;&#41;&#44; nervousness &#40;2&#46;9&#37;&#41;&#44; syncope &#40;2&#46;9&#37;&#41; and seizures &#40;2&#46;9&#37;&#41;&#46; The mean COHb level was 13&#46;9&#37; &#40;SD&#44; 5&#46;8&#41;&#46; Thirty-three patients required oxygen therapy &#40;97&#46;1&#37;&#41;&#44; and 13 &#40;39&#46;4&#37;&#41; were referred for hyperbaric chamber treatment&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">The visual inspection of the locale where the exposure took place verified the presence of a butane gas stove&#44; which&#44; despite being intended exclusively for outside use&#44; was used to rapidly heat a room of approximately 30<span class="elsevierStyleHsp" style=""></span>m<span class="elsevierStyleSup">2</span> used by the football group of Vilanova de la Barca &#40;Lleida&#41; to watch football matches&#46; The stove was lit at approximately 7&#58;30<span class="elsevierStyleHsp" style=""></span>pm&#44; and by 8&#58;15<span class="elsevierStyleHsp" style=""></span>pm the first cases had occurred&#46; The football match began at 8&#58;30<span class="elsevierStyleHsp" style=""></span>pm&#44; and&#44; according to the epidemic curve&#44; the largest number of cases showed up halfway through the match &#40;between 9&#58;15 and 9&#58;30<span class="elsevierStyleHsp" style=""></span>pm&#41; &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0050" class="elsevierStylePara elsevierViewall">Compared with the asymptomatic cases&#44; the participants with symptoms had a higher mean age &#40;48&#46;0 vs&#46; 16&#46;5 years&#59; <span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#46;003&#41; and&#44; logically&#44; a higher COHb level &#40;13&#46;9&#37; vs&#46; 4&#46;6&#37;&#59; <span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#46;005&#41; &#40;<a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a>&#41;&#46; The risk of poisoning was not associated with the distance from the stove or with the exposure time&#44; although the study lacked statistical power for explain this lack of association &#40;<a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a>&#41;&#46; Ten patients &#40;29&#46;5&#37;&#41; with confirmed cases presented no symptoms &#40;29&#46;5&#37;&#41;&#46; The asymptomatic cases had COHb levels similar to those of the symptomatic cases &#40;13&#46;6&#37; vs&#46; 15&#46;3&#37;&#59; <span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#62;<span class="elsevierStyleHsp" style=""></span>&#46;05&#41; but a shorter exposure time &#40;38&#46;3 vs&#46; 53&#46;3<span class="elsevierStyleHsp" style=""></span>min&#59; <span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#46;036&#41; &#40;<a class="elsevierStyleCrossRef" href="#tbl0010">Table 2</a>&#41;&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><elsevierMultimedia ident="tbl0010"></elsevierMultimedia></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0080">Discussion</span><p id="par0055" class="elsevierStylePara elsevierViewall">The study describes a mass CO poisoning with a very high attack rate due to the improper use of a butane stove in the interior of a social locale&#46; The poisoning was potentially severe for those affected by it&#44; and almost 40&#37; of the patients required oxygen treatment in a hyperbaric chamber&#46; We observed a high percentage of exposed individuals with COHb levels compatible with the definition of confirmed case but who were asymptomatic and still required treatment in a hyperbaric chamber&#46;</p><p id="par0060" class="elsevierStylePara elsevierViewall">The study has significant limitations&#46; The attack rate was extremely high &#40;87&#46;2&#37;&#41; which suggests that the environmental CO levels were very high&#46;<a class="elsevierStyleCrossRefs" href="#bib0115"><span class="elsevierStyleSup">4&#44;7</span></a> This finding is compatible with very high COHb concentrations observed in the cases &#40;mean&#44; 13&#46;9&#37;&#41;&#44; which were similar to those described in other published mass poisonings with severe cases&#46;<a class="elsevierStyleCrossRef" href="#bib0150"><span class="elsevierStyleSup">11</span></a> The youths had a lower risk of poisoning&#44; which could be explained by&#44; among other factors&#44; a lower exposure due to increased movement and their entering and exiting the locale&#46; It has been documented that the response to CO exposure varies with age&#46;<a class="elsevierStyleCrossRefs" href="#bib0125"><span class="elsevierStyleSup">6&#44;7</span></a> Although children and adolescents can present earlier symptoms&#44; they recover more rapidly due to their lower volume of blood and to greater ventilation per body mass unit&#46;<a class="elsevierStyleCrossRef" href="#bib0130"><span class="elsevierStyleSup">7</span></a></p><p id="par0065" class="elsevierStylePara elsevierViewall">The incident sounded a major alarm among the affected group&#44; which caused all of the exposed individuals to contact the emergency department&#46; This action helped verify that a high percentage of asymptomatic individuals presented COHb levels compatible with the definition of a case &#40;29&#46;5&#37;&#41; and who also required oxygen therapy or hyperbaric chamber treatment&#46; In fact&#44; the asymptomatic cases had COHb levels similar to those of the symptomatic cases&#46; The percentage of individuals with CO poisoning who remained asymptomatic in the published mass poisonings were&#44; in general&#44; not known because usually it is only those individuals with symptoms who go to healthcare services&#46;<a class="elsevierStyleCrossRefs" href="#bib0135"><span class="elsevierStyleSup">8&#44;9&#44;11</span></a> This study suggests that this percentage could be significant&#46; Consequently&#44; all individuals exposed to high CO levels&#44; in the context of mass exposure&#44; should be evaluated and have their COHb levels measured to determine whether they could benefit from oxygen therapy or hyperbaric chamber treatment&#46;<a class="elsevierStyleCrossRefs" href="#bib0115"><span class="elsevierStyleSup">4&#44;12</span></a> The risk of sequela in poisoned individuals can be high&#44; and various studies have indicated that hyperbaric oxygen could be of potential benefit to prevent sequela&#46;<a class="elsevierStyleCrossRefs" href="#bib0130"><span class="elsevierStyleSup">7&#44;12</span></a> Treatment with hyperbaric oxygen improves the arterial concentration and pressure of oxygen in the tissue&#44; promotes the elimination of CO and reduces oxidative stress and inflammation&#46;<a class="elsevierStyleCrossRef" href="#bib0155"><span class="elsevierStyleSup">12</span></a> In fact&#44; it is recommended that patients poisoned by CO undergo medical follow-up after being discharged&#46; The recovery rate after poisoning varies and is often complicated by the onset of sequela that can persist after the exposure or develop weeks after the event&#46;<a class="elsevierStyleCrossRefs" href="#bib0160"><span class="elsevierStyleSup">13&#8211;16</span></a></p><p id="par0070" class="elsevierStylePara elsevierViewall">The butane stove that caused the poisoning had been previously used&#46; Two days earlier&#44; a member of the same group with prior renal failure presented symptoms of syncope while seated beside the stove&#46; However&#44; this episode was not related to a potential CO poisoning&#46; This case could be revealing for potential episodes of previous inadvertent poisonings&#46; In fact&#44; poisonings can occur without resulting in symptoms&#44; as demonstrated in the mass poisoning described above&#44; or in mild symptoms that are not diagnosed as CO poisoning&#46;<a class="elsevierStyleCrossRefs" href="#bib0135"><span class="elsevierStyleSup">8&#44;9&#44;11&#44;17&#44;18</span></a> Therefore&#44; it is important that emergency departments&#44; when faced with nonspecific conditions of headache&#44; nausea&#44; muscle weakness and dizziness&#44; consider a possible CO poisoning as a cause of the symptoms&#44; especially in winter&#46;<a class="elsevierStyleCrossRefs" href="#bib0100"><span class="elsevierStyleSup">1&#44;11&#44;17&#44;18</span></a> Additionally&#44; due to the financial crisis&#44; the use of cheaper heating systems can result in greater exposure and risk of CO poisonings&#46;<a class="elsevierStyleCrossRefs" href="#bib0135"><span class="elsevierStyleSup">8&#44;9</span></a> Thus&#44; it is important that both the public and practitioners have the necessary information to prevent and detect this problem&#46;<a class="elsevierStyleCrossRefs" href="#bib0105"><span class="elsevierStyleSup">2&#44;18&#44;19</span></a></p><p id="par0075" class="elsevierStylePara elsevierViewall">Other measures that can help control these poisonings are the proper use of heating devices and domestic hot water heaters&#44; avoiding the use of combustion engines inside houses&#44; the periodic inspection of the devices to ensure correct operation and the availability of alarms to detect high CO levels in risk situations&#46;<a class="elsevierStyleCrossRefs" href="#bib0130"><span class="elsevierStyleSup">7&#44;11</span></a></p><p id="par0080" class="elsevierStylePara elsevierViewall">The study has a number of limitations&#46; The patients&#8217; COHb readings were performed when they contacted the emergency department&#46; Most of the patients contacted the department 30<span class="elsevierStyleHsp" style=""></span>min to 3<span class="elsevierStyleHsp" style=""></span>h after the exposure&#44; but a number of them did so the following day when more than 12<span class="elsevierStyleHsp" style=""></span>h had elapsed&#46; Given that COHb levels decrease rapidly over time after the exposure&#44; the levels detected would be lower than those to which the patients were truly exposed&#46; Most of the patients arrived at the locale at the start of the football match&#44; but some arrived before the stove was lit&#46; The epidemic curve is therefore not a reliable reflection of the start of exposure for all those exposed&#46; The exposure time and distance from the stove were difficult to determine&#44; given that a number of the individuals changed position over the course of the match&#44; and some&#44; especially children&#44; exited the locale a few times&#46;</p><p id="par0085" class="elsevierStylePara elsevierViewall">In conclusion&#44; we report a mass CO poisoning in which a high percentage of individuals who were confirmed to be poisoned &#40;according to COHb levels&#41; were asymptomatic&#46; Therefore&#44; we recommend assessing COHb levels in all individuals exposed to mass CO poisonings&#44; even if they have no symptoms&#46; The public and health practitioners should be informed of the risk of CO poisoning&#44; especially in winter when using heating systems that can generate CO&#46;<a class="elsevierStyleCrossRef" href="#bib0185"><span class="elsevierStyleSup">18</span></a></p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0085">Conflict of interests</span><p id="par0090" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflicts of interest&#46;</p></span></span>"
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            2 => "Outbreak"
            3 => "Epidemiology"
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            0 => "Intoxicaci&#243;n"
            1 => "Mon&#243;xido de carbono"
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        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Background</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">The objective was to study a mass carbon monoxide &#40;CO&#41; poisoning and the characteristics of the asymptomatic cases&#46;</p></span> <span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Methods</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">On the 2nd of February&#44; 2015&#44; a group of more than 30 television viewers of a football match contacted the emergency department due to suspected CO poisoning from a butane stove&#46; A visual inspection of the location of the exposure and a descriptive epidemiological study were conducted&#46; Based on the type of variable&#44; the presence of a statistical association was studied with Fisher&#39;s exact test or the Kruskal&#8211;Wallis test&#46;</p></span> <span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Results</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Thirty-four of the 39 individuals were affected &#40;87&#46;2&#37;&#41;&#46; The exposed individuals had a mean age of 43&#46;8 years &#40;SD&#44; 22&#46;1&#41;&#44; and 28&#46;2&#37; &#40;11&#47;39&#41; were women&#46; The time of exposure was 52&#46;4<span class="elsevierStyleHsp" style=""></span>min &#40;SD&#44; 21&#46;0&#41;&#44; and the mean distance from the oven was 4&#46;2<span class="elsevierStyleHsp" style=""></span>m &#40;SD&#44; 2&#46;5&#41;&#46; The most common symptoms were headache &#40;50&#37;&#41;&#44; nausea &#40;20&#46;6&#37;&#41;&#44; weakness &#40;20&#46;6&#37;&#41; and dizziness &#40;14&#46;7&#37;&#41;&#46; The carboxyhaemoglobin &#40;COHb&#41; levels were very high &#40;13&#46;8<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>5&#46;8&#37;&#41;&#46; Some 97&#46;1&#37; of the individuals required oxygen therapy&#44; and 39&#46;4&#37; required hyperbaric chamber treatment&#46; Some 29&#46;5&#37; of the cases had no symptoms but showed COHb levels similar to those that did have symptoms &#40;13&#46;6&#37; vs&#46; 15&#46;3&#37;&#44; nonsignificant difference&#41;&#46; The asymptomatic cases had a shorter exposure time &#40;38&#46;3<span class="elsevierStyleHsp" style=""></span>min vs&#46; 53&#46;3<span class="elsevierStyleHsp" style=""></span>min&#59; <span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#46;036&#41;&#46;</p></span> <span id="abst0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Conclusions</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Almost a third of the exposed individuals were asymptomatic&#44; even with COHb levels similar to those of the symptomatic patients&#44; and the majority of these asymptomatic patients even required oxygen treatment in a hyperbaric chamber&#46;</p></span>"
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        "resumen" => "<span id="abst0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Introducci&#243;n</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">El objetivo fue estudiar un brote de intoxicaci&#243;n por mon&#243;xido de carbono &#40;CO&#41; y las caracter&#237;sticas de los casos asintom&#225;ticos&#46;</p></span> <span id="abst0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">M&#233;todos</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">El 2 de febrero de 2015 un grupo de m&#225;s de 30 telespectadores de un partido de f&#250;tbol contact&#243; con el servicio de urgencias por una supuesta intoxicaci&#243;n por CO procedente de una estufa de butano&#46; Se realiz&#243; una inspecci&#243;n ocular del local de la exposici&#243;n y un estudio epidemiol&#243;gico descriptivo&#46; Seg&#250;n el tipo de variables&#44; la existencia de una asociaci&#243;n estad&#237;stica se estudi&#243; con la prueba exacta de Fisher o el test de Kruskal&#8211;Wallis&#46;</p></span> <span id="abst0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Resultados</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Se vieron afectados 34 de 39 sujetos &#40;87&#44;2&#37;&#41;&#46; Los expuestos ten&#237;an una media de edad de 43&#44;8<span class="elsevierStyleHsp" style=""></span>a&#241;os &#40;DE<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>22&#44;1&#41; y el 28&#44;2&#37; &#40;11&#47;39&#41; eran mujeres&#46; El tiempo de exposici&#243;n fue de 52&#44;4<span class="elsevierStyleHsp" style=""></span>min &#40;DE<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>21&#44;0&#41; y la distancia a la estufa de 4&#44;2<span class="elsevierStyleHsp" style=""></span>m &#40;DE<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>2&#44;5&#41;&#46; Los s&#237;ntomas m&#225;s frecuentes fueron cefalea &#40;50&#37;&#41;&#44; n&#225;useas &#40;20&#44;6&#37;&#41;&#44; p&#233;rdida de fuerza &#40;20&#44;6&#37;&#41; y v&#233;rtigo &#40;14&#44;7&#37;&#41;&#46; Los niveles de carboxihemoglobina &#40;COHb&#41; fueron muy elevados &#40;13&#44;8&#37;<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>5&#44;8&#41;&#46; El 97&#44;1&#37; precis&#243; oxigenoterapia y el 39&#44;4&#37; tratamiento en c&#225;mara hiperb&#225;rica&#46; Un 29&#44;5&#37; de los casos no presentaron s&#237;ntomas&#44; y respecto a los casos sintom&#225;ticos&#44; estos mostraron niveles similares de COHb &#40;13&#44;6&#37; vs&#46; 15&#44;3&#37;&#44; diferencia no significativa&#41;&#44; pero un tiempo de exposici&#243;n inferior &#40;38&#44;3<span class="elsevierStyleHsp" style=""></span>min vs&#46; 53&#44;3<span class="elsevierStyleHsp" style=""></span>min&#59; p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;036&#41;&#46;</p></span> <span id="abst0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Conclusiones</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Casi una tercera parte de las personas expuestas fueron asintom&#225;ticas aun con niveles de COHb similares a los casos sintom&#225;ticos&#44; e incluso la mayor&#237;a precisaron tratamiento con ox&#237;geno en c&#225;mara hiperb&#225;rica&#46;</p></span>"
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        "nota" => "<p class="elsevierStyleNotepara" id="npar0015">Please cite this article as&#58; Godoy P&#44; Pont C&#44; Artigues A&#44; Alsed&#224; M&#46; Brote masivo de intoxicaci&#243;n por mon&#243;xido de carbono en los telespectadores de un partido de f&#250;tbol&#46; Rev Clin Esp&#46; 2016&#59;216&#58;409&#8211;413&#46;</p>"
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          "en" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Epidemic curve for the onset of cases from a mass carbon monoxide poisoning by a butane stove&#46;</p>"
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          "leyenda" => "<p id="spar0055" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleItalic">Abbreviation</span>&#58; COHb&#44; carboxyhemoglobin&#46;</p>"
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">15&#46;6 &#40;16&#46;5&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleItalic">Smoker</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Yes&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>No&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">29 &#40;85&#46;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4 &#40;80&#46;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleItalic">Chronic diseases</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Yes&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>No&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">13&#46;9 &#40;5&#46;8&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4&#46;0 &#40;2&#46;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5&#46;4 &#40;2&#46;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#62;&#46;05&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleItalic">Chronic diseases</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Yes&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="4" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">COHb &#40;&#37;&#41;</span><a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">a</span></a>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#62;&#46;05&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Distance from the stove</span>&#44; <span class="elsevierStyleItalic">m</span><a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">a</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4&#46;0 &#40;2&#46;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3&#46;8 &#40;2&#46;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#62;&#46;05&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">38&#46;3 &#40;21&#46;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#60;&#46;036&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
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          "identificador" => "bibs0005"
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            0 => array:3 [
              "identificador" => "bib0100"
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                    0 => array:2 [
                      "titulo" => "Carbon monoxide poisoning in patients presenting to the emergency department with a headache in winter months"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "N&#46; Zorbalar"
                            1 => "M&#46;A&#46;E&#46; Yesilaras"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Emerg Med J"
                        "fecha" => "2014"
                        "volumen" => "31"
                        "paginaInicial" => "66"
                        "paginaFinal" => "70"
                      ]
                    ]
                  ]
                ]
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            1 => array:3 [
              "identificador" => "bib0105"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Review of unintentional non-fire-related carbon monoxide poisoning morbidity and mortality in Florida&#44; 1999&#8211;2007"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "L&#46; Harduar-Morano"
                            1 => "S&#46; Watkins"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Public Health Rep"
                        "fecha" => "2011"
                        "volumen" => "126"
                        "paginaInicial" => "240"
                        "paginaFinal" => "250"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21387954"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0110"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "National carbon monoxide poisoning surveillance framework and recent estimates"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "S&#46; Iqbal"
                            1 => "J&#46;H&#46; Clower"
                            2 => "M&#46; King"
                            3 => "J&#46; Bell"
                            4 => "F&#46;Y&#46; Yip"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
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Original article
Mass carbon monoxide poisoning among television viewers of a football match
Brote masivo de intoxicación por monóxido de carbono en los telespectadores de un partido de fútbol
P. Godoya,b,c,
Corresponding author
pere.godoy@gencat.cat

Corresponding author.
, C. Pontb, A. Artiguesa, M. Alsedàa,b
a Agencia de Salud Pública de Cataluña, Generalidad de Cataluña, Barcelona, Spain
b Institut de Recerca Biomèdica (IRB) de Lleida, Facultad de Medicina, Universidad de Lleida, Lleida, Spain
c CIBER de Epidemiología y Salud Pública (CIBERESP), Spain

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