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        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Backgroud and objectives</span><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">As patients with diabetes are at a significantly higher risk of cardiovascular diseases than those without diabetes&#44; it is important to gain a clinical understanding of the differential effects of smoking cessation on several risk factors between patients with and without diabetes&#46;</p></span> <span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Materials and methods</span><p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">Patients who participated in a smoking cessation program received an assessment of the outcomes of interest&#46; The outcomes were changes in metabolic parameters and renal function from baseline to 6-month follow-up after the smoking cessation program&#46;</p></span> <span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Result</span><p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">A total of 1&#44;954 patients joined the smoking cessation program&#44; and 1&#44;381 patients were in the smoking cessation failure &#40;SCF&#41; group and 573 were in the smoking cessation success &#40;SCS&#41; group&#46; The decrease in HbA1c after smoking cessation was only observed in patients with diabetes&#46; Smoking cessation was also associated with a significant decrease in LDL cholesterol in patients with diabetes&#46; In terms of renal function&#44; smoking cessation was associated with an improvement in eGFR&#44; and the trend was similar in patients with and without diabetes&#46;</p></span> <span id="abst0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Conclusion</span><p id="spar0060" class="elsevierStyleSimplePara elsevierViewall">Successful smoking cessation was associated with improvement in renal function&#46; Moreover&#44; it was associated with improvements in HbA1c and LDL cholesterol in patients with diabetes&#44; despite significant weight gain&#46;</p></span>"
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        "resumen" => "<span id="abst0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Antecedentes y objetivos</span><p id="spar0065" class="elsevierStyleSimplePara elsevierViewall">Dado que los pacientes con diabetes tienen un riesgo significativamente mayor de sufrir enfermedades cardiovasculares que aquellos sin diabetes&#44; es importante obtener una comprensi&#243;n cl&#237;nica de los efectos diferenciales de dejar de fumar sobre varios factores de riesgo entre pacientes con y sin diabetes&#46;</p></span> <span id="abst0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Materiales y m&#233;todos</span><p id="spar0070" class="elsevierStyleSimplePara elsevierViewall">Los pacientes que participaron en un programa para dejar de fumar recibieron una evaluaci&#243;n de los resultados de inter&#233;s&#46; Los resultados fueron cambios en los par&#225;metros metab&#243;licos y la funci&#243;n renal desde el inicio hasta el seguimiento de 6 meses despu&#233;s del programa para dejar de fumar&#46;</p></span> <span id="abst0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Resultado</span><p id="spar0075" class="elsevierStyleSimplePara elsevierViewall">Un total de 1&#46;954 pacientes se unieron al programa para dejar de fumar&#44; 1&#46;381 pacientes estaban en el grupo de fracaso para dejar de fumar &#40;SCF&#41; y 573 estaban en el grupo de &#233;xito para dejar de fumar &#40;SCS&#41;&#46; La disminuci&#243;n de la HbA1c tras dejar de fumar s&#243;lo se observ&#243; en pacientes con diabetes&#46; Dejar de fumar tambi&#233;n se asoci&#243; con una disminuci&#243;n significativa del colesterol LDL en pacientes con diabetes&#46; En t&#233;rminos de funci&#243;n renal&#44; dejar de fumar se asoci&#243; con una mejora en la TFGe&#44; y la tendencia fue similar en pacientes con y sin diabetes&#46;</p></span> <span id="abst0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Conclusi&#243;n</span><p id="spar0080" class="elsevierStyleSimplePara elsevierViewall">Dejar de fumar exitosamente se asoci&#243; con una mejora en la funci&#243;n renal&#46; Adem&#225;s&#44; se asoci&#243; con mejoras en la HbA1c y el colesterol LDL en pacientes con diabetes&#44; a pesar de un aumento de peso significativo&#46;</p></span>"
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Original article
DOI: 10.1016/j.rceng.2024.10.010
Pre-proof, online 4 November 2024
Impact of smoking cessation on metabolic parameters and renal function in patients with and without diabetes mellitus
Impacto del abandono del hábito de fumar sobre los parámetros metabólicos y la función renal en pacientes con y sin diabetes mellitus
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C.-P. Fua,b,c,d, P.-K. Fua,e, M.-C. Luc, Y.-Y. Liaoe, J.-S. Wanga,c,f,g,
Corresponding author
jswang@vghtc.gov.tw

Corresponding author at: Taichung Veterans General Hospital, No.1650, Sec. 4, Taiwan Boulevard, Taichung 407219, Taiwan.
a Department of Medicine, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan
b Graduate Institute of Biomedical Electronics and Bioinformatics, College of Electrical Engineering and Computer Science, National Taiwan University, Taipei, Taiwan
c Division of Endocrinology and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan
d Department of Medicine, Chung Shan Medical University, Taichung, Taiwan
e Smoking Cessation Treatment and Management Center, Taichung Veterans General Hospital, Taichung, Taiwan
f Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung, Taiwan
g Diabetes Center, Taichung Veterans General Hospital, Taichung, Taiwan

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