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Navarro-Triviño" "autores" => array:1 [ 0 => array:3 [ "nombre" => "F.J." "apellidos" => "Navarro-Triviño" "email" => array:1 [ 0 => "fntmed@gmail.com" ] ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Servicio de Dermatología y Venereología, Hospital Universitario San Cecilio, Granada, Spain" "identificador" => "aff0005" ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Pápulas asintomáticas eruptivas faciales" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1253 "Ancho" => 2083 "Tamanyo" => 265720 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0005" "detalle" => "Figure 1." "rol" => "short" ] ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">An 82-year-old man with no personal history of interest was admitted for a papula in the nasal area that bled easily. In terms of family history, one of the patient’s children experienced 6 episodes of pneumothorax, which was ultimately resolved with pleurodesis. During the physical examination (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>), we observed a papular lesion with a scab in the right nasal ala (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>B). We observed multiple translucent, skin-colored papules distributed in a generalized manner over the rest of the face (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>A). The patient reported that they had appeared over the past year. The histopathology results were compatible with fibrofolliculoma. We requested thoracoabdominal computed tomography, which showed numerous cystic lesions in both kidneys, associated with a larger tumor mass. The lung parenchyma showed no associated lesions. The patient was referred to the oncology department for study and treatment.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">Birt-Hogg Dubé syndrome is an uncommon, autosomal dominant disease that usually starts in adulthood. Although its etiology is unknown, the disease has been reported in relation to a mutation of the FLCN gene in chromosome 17p22. This gene encodes folliculin, which is suspected to participate in the mTOR pathway and is mainly implicated in the development of renal tumors. The rapid onset of multiple facial papules, whose histopathological diagnosis is fibrofolliculoma, requires physicians to rule out the presence of internal organ tumors, especially in the kidneys. A personnel or family history of pneumothorax should alert clinicians to this condition, given that pulmonary cysts are another manifestation of this syndrome. The prognosis depends on the presence of malignant tumors, given that skin lesions are indolent.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2019-07-27" "fechaAceptado" => "2019-07-31" "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Navarro-Triviño FJ. Pápulas asintomáticas eruptivas faciales. 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Medicine in Images
Asymptomatic eruptive facial papules
Pápulas asintomáticas eruptivas faciales
F.J. Navarro-Triviño
Servicio de Dermatología y Venereología, Hospital Universitario San Cecilio, Granada, Spain