Journal Information
Vol. 222. Issue 8.
Pages 506 (October 2022)
Vol. 222. Issue 8.
Pages 506 (October 2022)
Correspondence
Full text access
Type 2 diabetes mellitus in elderly or frail individuals. Topics to be considerer
Diabetes mellitus tipo 2 en las personas de edad avanzada o frágiles. Aspectos a tener en cuenta
Visits
70
F. Formigaa,
Corresponding author
fformiga@bellvitgehospital.cat

Corresponding author.
, L. Rodríguez-Mañasb
a Unidad de Geriatría, Servicio de Medicina Interna, Hospital Universitari de Bellvitge, IDIBELL, L’Hospitalet de Llobregat, Barcelona, Spain
b Servicio de Geriatría, Hospital Universitario de Getafe, Getafe, Madrid, Spain
This item has received
Article information
Full Text
Bibliography
Download PDF
Statistics
Full Text
Dear Director,

The prevalence of type 2 diabetes mellitus increases with age and is associated with a high prevalence of frailty1. Therefore, we read with great interest the update to the consensus document Type 2 diabetes mellitus in elderly or frail individuals2, written by experts in type 2 diabetes mellitus. We believe that the participation of experts in frailty and older adults would have allowed for incorporating important concepts into the document, such as a differentiated approach recommended according to the frailty phenotype which, in turn, is associated with different metabolic phenotypes.

As an example, there is the phenotype of a malnourished anorexic patient with reduced insulin resistance and a high risk of hypoglycemia, in which the approach would prioritize treatment deintensification, and the phenotype of an obese sarcopenic individual with greater insulin resistance and a lower risk of hypoglycemia, which would allow for treatment intensification3.

We would also like to emphasize that by understanding frailty as an ongoing, multisystemic, dynamic, and potentially reversible process, intensifying measures to avoid, halt, or try to reverse its onset is fundamental in patients with type 2 diabetes mellitus1. Therefore, it is important to disseminate the results of the MID-Frail study, a multicenter, cluster-randomized clinical trial, which support this premise. Participants in the intervention group received a multimodal intervention that entailed an individualized, progressive resistance exercise program for 16 weeks; a structured diabetes and nutritional education program taught in seven sessions; and training to ensure optimal diabetes care. After 12 months, the intervention group participants had significantly higher scores on the Short Physical Performance Battery (SPPB) and the program was cost-effective4.

These and other aspects related to older adult patients which seriously compromise their clinical management should be incorporated into future editions of the consensus document, in accordance with internationally accepted recommendations5.

References
[1]
F. Formiga, L. Rodríguez Mañas.
Paciente anciano con diabetes mellitus y fragilidad. ¿Asociación siempre presente?.
Rev Esp Geriatr Gerontol, 49 (2014), pp. 253-254
[2]
F. Gómez-Peralta, F.J. Carrasco-Sánchez, A. Pérez, J. Escalada, F. Álvarez-Guisasola, C. Miranda-Fernández-Santos, et al.
Resumen ejecutivo sobre tratamiento de la diabetes mellitus tipo 2 en personas de edad avanzada o frágiles. Actualización 2022 del documento de consenso 2018 «Tratamiento de la diabetes mellitus tipo 2 en el paciente anciano».
Rev Clin Esp, 222 (2022), pp. 496-499
[3]
A.H. Abdelhafiz, D. Emmerton, A.J. Sinclair.
Impact of frailty metabolic phenotypes on the management of older people with type 2 diabetes mellitus.
Geriatr Gerontol Int, 21 (2021), pp. 614-622
[4]
L. Rodriguez-Mañas, O. Laosa, B. Vellas, G. Paolisso, E. Topinkova, J. Oliva-Moreno, et al.
European MID-Frail Consortium. Effectiveness of a multimodal intervention in functionally impaired older people with type 2 diabetes mellitus.
J Cachexia Sarcopenia Muscle, 10 (2019), pp. 721-733
[5]
M.N. Munshi, G.S. Meneilly, L. Rodríguez-Mañas, K.L. Close, P.R. Conlin, T. Cukierman-Yaffe, et al.
Diabetes in ageing: pathways for developing the evidence base for clinical guidance.
Lancet Diabetes Endocrinol, 8 (2020), pp. 855-867

Please cite this article as: Formiga F, Rodríguez-Mañas L. Diabetes mellitus tipo 2 en las personas de edad avanzada o frágiles. Aspectos a tener en cuenta. Rev Clin Esp. 2022;222:506.

Copyright © 2022. Elsevier España, S.L.U. and Sociedad Española de Medicina Interna (SEMI)
Idiomas
Revista Clínica Española (English Edition)
Article options
Tools
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?