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Controlled ADA1: in ≤75 years HbA1c <7% and in >75 years HbA1c <7.5%; controlled ADA2: in ≤75 years HbA1c <7% and in >75 years HbA1c <8.0%; controlled RedGDPS: in ≤75 years HbA1c <7% and in >75 years HbA1c <8.5%. Abbreviations: ADA: American Diabetes Association; RedGDPS: Network of Study Groups for Diabetes in Primary Health Care." ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "J. Escribano Serrano, M.I. Méndez-Esteban, A. García-Bonilla, M. Márquez-Ferrando, C. Casto-Jarillo, E. Berruguilla Pérez, M.M. Calero Ruiz, M.L. Gonzalez Borrachero, J.D. Santotoribio, A. Michán-Doña" "autores" => array:10 [ 0 => array:2 [ "nombre" => "J." "apellidos" => "Escribano Serrano" ] 1 => array:2 [ "nombre" => "M.I." "apellidos" => "Méndez-Esteban" ] 2 => array:2 [ "nombre" => "A." "apellidos" => "García-Bonilla" ] 3 => array:2 [ "nombre" => "M." "apellidos" => "Márquez-Ferrando" ] 4 => array:2 [ "nombre" => "C." "apellidos" => "Casto-Jarillo" ] 5 => array:2 [ "nombre" => "E." 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"apellidos" => "Michán-Doña" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0014256518303084" "doi" => "10.1016/j.rce.2018.10.005" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0014256518303084?idApp=WRCEE" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2254887419300037?idApp=WRCEE" "url" => "/22548874/0000021900000004/v1_201904260621/S2254887419300037/v1_201904260621/en/main.assets" ] ] "en" => array:12 [ "idiomaDefecto" => true "cabecera" => "Editorial" "titulo" => "The consumption of antidiabetic agents in large populations: a new tool for understanding diabetes mellitus" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "196" "paginaFinal" => "197" ] ] "autores" => array:1 [ 0 => array:3 [ "autoresLista" => "J.F. Gómez Cerezo" "autores" => array:1 [ 0 => array:3 [ "nombre" => "J.F. Gómez" "apellidos" => "Cerezo" "email" => array:1 [ 0 => "jgomezpalomares@gmail.com" ] ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Jefe de Servicio de Medicina Interna. Hospital Universitario Infanta Sofía. San Sebastián de los Reyes" "identificador" => "aff0005" ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "El consumo de antidiabéticos en grandes poblaciones: una nueva herramienta para el conocimiento de la diabetes mellitus" ] ] "textoCompleto" => "It is well known that diabetes mellitus and its complications constitute a fundamental problem for the health of the Spanish population and that its increased incidence is mainly associated with the increased excess weight and obesity rates. In recent years, however, the evolution of its prevalence has indicated a different pattern, even showing negative interannual variation rates. A recent study examined the prevalence of diabetes mellitus in Spain by analyzing the various national health surveys on diabetes mellitus conducted in Spain between 1999 and 2014. The prevalence of diabetes mellitus in 2014 was 7.3% in men and 6.4% in women, showing that the exponential increase witnessed in previous decades showed a tendency to stabilize and, in some cases, diminish.<a class="elsevierStyleCrossRef" href="#bib0005">1</a> These results are similar to those encountered outside Spain; in 2015, the prevalence of diagnosed diabetes mellitus in the US was 7.2%.<a class="elsevierStyleCrossRef" href="#bib0010">2</a>These results did not significantly differ when registries with data from electronic medical records were employed as sources. Thus, the recent Epichronic study conducted in Navarra and the Basque Country found a prevalence that ranged from 6.6% to 7% in the population older than 20 years.<a class="elsevierStyleCrossRef" href="#bib0015">3</a>Measuring drug consumption, through an analysis of large databases, is considered a valid method for determining the incidence and prevalence of diseases and is equally valid in the case of diabetes mellitus.<a class="elsevierStyleCrossRef" href="#bib0020">4</a> In a recent study that employed the consumption of antidiabetic drugs as the source showed a prevalence of diabetes mellitus of 8.3% in the population of Extremadura (Spain).<a class="elsevierStyleCrossRef" href="#bib0025">5</a> Through an analysis of the consumption of antidiabetic agents, the interesting article published in this issue by Escribano et al. shows that the prevalence of diabetes in the province of Cadiz (Spain) between 2014 and 2016 varied between 8.65% and 8.83% of the population.<a class="elsevierStyleCrossRef" href="#bib0030">6</a> These data provide reliable information on the state of affairs of a specific area of Spain (the province of Cadiz), with readings that are higher than the national average provided by surveys.<a class="elsevierStyleCrossRef" href="#bib0005">1</a> These results make it advisable to plan future studies to help establish the environmental and individual factors that explain this local increase in the prevalence of diabetes. As the authors themselves mentioned, this type of study based on drug consumption does not allow us to exactly establish the prevalence because the study does not take into account individuals with diabetes but with no drug treatment or the still undiagnosed patient population. Considering the population with diabetes who were not diagnosed before the health survey, the prevalence of diabetes in the US in 2015 rose to 9.4% of the population.<a class="elsevierStyleCrossRef" href="#bib0010">2</a>It is also relevant that in the study by Escribano et al.<a class="elsevierStyleCrossRef" href="#bib0030">6</a> the blood glucose control objective was achieved in 69% of the patients with diabetes. It is also undoubtedly a highly significant fact that 78% of those older than 75 years showed glycated hemoglobin readings below 7.5%. This degree of control is greater than the 43.2% found by Formiga et al. in patients with diabetes older than 65 years.<a class="elsevierStyleCrossRef" href="#bib0035">7</a> However, this excellent control of glycated hemoglobin in elderly patients can be a double-edged sword. We have no information on the number and severity of hypoglycemia in these patients, and without this information, we cannot determine with certainty the risks assumed with this high degree of blood glucose control. However, we can assure that, in the case of frail elderly patients, this approach would be inadvisable.In conclusion, the studies on diabetes based on the consumption of antidiabetic drugs and conducted with large databases are an excellent source of reliable information on the prevalence of diabetes, control of the disease, drug consumption, compliance with the objectives and the degree of compliance with the recommendations of the clinical guidelines. These studies are undoubtedly the prelude to new advances in diabetes research, which will arrive with the possibility of obtaining information offered by the management of “big data” from electronic medical records." "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "Please cite this article as: Cerezo JG. El consumo de antidiabéticos en grandes poblaciones: una nueva herramienta para el conocimiento de la diabetes mellitus . https://doi.org/10.1016/j.rce.2019.03.003, 10.1016/j.rceng.2019.01.002." ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0015" "bibliografiaReferencia" => array:7 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Evolución de la prevalencia de la diabetes mellitus en España (1999-2014)" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "M.J. López Rey" 1 => "M. Docampo García" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.endinu.2018.06.006" "Revista" => array:6 [ "tituloSerie" => "Endocrinol Diabetes Nutr." "fecha" => "2018" "volumen" => "65" "paginaInicial" => "515" "paginaFinal" => "523" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/30078493" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:1 [ "referenciaCompleta" => "National Diabetes Statistics Report, 2017 Estimates of Diabetes and Its Burden in the United States. https://www.cdc.gov/diabetes/pdfs/data/statistics/national-diabetes-statistics-report.pdf." ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "National health care database utilization between Spain and France: results from the epichronic study assessing the prevalence of type 2 diabetes mellitus" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "G. Moulis" 1 => "B. Ibáñez" 2 => "A. Palmaro" 3 => "F. Aizpuru" 4 => "E. Millán" 5 => "M. Lapeyre-Mestre" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.2147/CLEP.S151890" "Revista" => array:6 [ "tituloSerie" => "Clinical Epidemiology" "fecha" => "2018" "volumen" => "10" "paginaInicial" => "863" "paginaFinal" => "874" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/30100760" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:1 [ "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "S. Sinnott" 1 => "S. McHugh" 2 => "H. Whelton" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1136/bmjdrc-2016-000288" "Revista" => array:5 [ "tituloSerie" => "Estimating the prevalence and incidence of type 2 diabetes using population level pharmacy claims data: a cross-sectional study BMJ Open Diabetes Research and Care" "fecha" => "2017" "volumen" => "5" "paginaInicial" => "e000288" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/28123753" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0025" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:3 [ "comentario" => "(in press)" "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Prevalence of diabetes and frequency of glycated haemoglobin monitoring in Extremadura (Spain) during 2012, 2013 and 2014: An observational study" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "A. Barquilla García" 1 => "J. Sánchez Vega" 2 => "J.C. Romero Vigara" 3 => "L. Fernández" 4 => "M.J. Gamero Samino" 5 => "F. Buitrago" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.pcd.2018.12.006" "Revista" => array:2 [ "tituloSerie" => "Prim. Care Diab." "fecha" => "2019" ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0030" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Prevalencia de diabetes, utilización de antidiabéticos y grado de control glucémico en la provincia de Cádiz (2014-2016): un estudio de base poblacional" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "J. Escribano Serrano" 1 => "M.I. Méndez-Esteban" 2 => "A. García-Bonilla" 3 => "M. Márquez-Ferrando" 4 => "C. Casto-Jarillo" 5 => "E. Berruguilla Pérez" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Rev Clin Esp." "fecha" => "2019" "volumen" => "219" "paginaInicial" => "177" "paginaFinal" => "183" ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0035" "etiqueta" => "7" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Inadequate glycaemic control and therapeutic management of adults over 65 years old with type 2 diabetes mellitus in Spain" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "F. Formiga" 1 => "J. Franch-Nadal" 2 => "L. Rodriguez" 3 => "L. Ávila" 4 => "E. Fuster" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Nutr Health Aging." "fecha" => "2017" "volumen" => "21" "paginaInicial" => "1365" "paginaFinal" => "1370" ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/22548874/0000021900000004/v1_201904260621/S225488741930089X/v1_201904260621/en/main.assets" "Apartado" => array:4 [ "identificador" => "72714" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Editorials" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/22548874/0000021900000004/v1_201904260621/S225488741930089X/v1_201904260621/en/main.pdf?idApp=WRCEE&text.app=https://revclinesp.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S225488741930089X?idApp=WRCEE"]

Revista Clínica Española (English Edition)

ISSN: 2254-8874

Revista Clínica Española published its first issue in 1940 and is the body of expression of the Spanish Society of Internal Medicine (SEMI).
The journal fully endorses the goals of updating knowledge and facilitating the acquisition of key developments in internal medicine applied to clinical practice. Revista Clínica Española is subject to a thorough double blind review of the received articles written in Spanish or English. Ten issues are published each year, including mostly originals, reviews and consensus documents.

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2.3

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0.7

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0.162

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0.211

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