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We indeed agree on the need for comprehensive care programs composed of a multidisciplinary team that includes primary care physicians and internists, among others, in the overall management of patients with retinal venous thrombosis. Additionally, it would be highly beneficial to formally reference this aspect in clinical practice guidelines.<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1–3</span></a> Therefore, we encourage further work in this direction and continued research in the field of retinal venous thrombosis.</p><p id="par0010" class="elsevierStylePara elsevierViewall">Regarding angiographic diagnosis, as appropriately stated in the reply letter, a clinical diagnosis based on history and characteristic ophthalmologic examination can be made (which is the most commonly performed diagnostic method in actual medical practice). However, fluorescein angiography can also be used to confirm the diagnosis of retinal vein occlusion (RVO) and evaluate the degree of retinal perfusion deficit (typically performed during the initial assessment). This imaging test is also useful in objectively assessing retinal capillary perfusion deficit to evaluate the risk of neovascularization, the need for follow-up and prognosis, and guide the most appropriate therapeutic approach.<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> Indeed, this test requires more time due to its duration and involves intravenous contrast administration.</p><p id="par0015" class="elsevierStylePara elsevierViewall">Furthermore, optical coherence tomography (OCT) of the macula is primarily used to quantify retinal thickening caused by intraretinal fluid in cases of macular edema<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a> and determine its progression during follow-up. 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Correspondence
Response to letter: “Recommendations for systemic diagnosis and management in clinical practice guidelines for retinal vein occlusion (RVO)”
Respuesta a carta réplica: «Recomendaciones de diagnóstico y manejo sistémico en las guías de práctica clínica de la oclusión venosa retiniana (OVR)»
Leticia Guirado-Torrecillas
Unidad de Trombosis, Servicio de Medicina Interna, Hospital Clínico Universitario Virgen de la Arrixaca, Murcia, Spain