array:24 ["pii" => "S2254887417300346" "issn" => "22548874" "doi" => "10.1016/j.rceng.2017.01.003" "estado" => "S300" "fechaPublicacion" => "2017-06-01" "aid" => "1368" "copyright" => "Elsevier España, S.L.U. and Sociedad Española de Medicina Interna (SEMI)" "copyrightAnyo" => "2016" "documento" => "article" "crossmark" => 1 "subdocumento" => "fla" "cita" => "Rev Clin Esp. 2017;217:296-8" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 2 "PDF" => 2 ] "Traduccion" => array:1 [ "es" => array:19 [ "pii" => "S0014256517300553" "issn" => "00142565" "doi" => "10.1016/j.rce.2017.01.013" "estado" => "S300" "fechaPublicacion" => "2017-06-01" "aid" => "1368" "copyright" => "Elsevier España, S.L.U. and Sociedad Española de Medicina Interna (SEMI)" "documento" => "article" "crossmark" => 1 "subdocumento" => "fla" "cita" => "Rev Clin Esp. 2017;217:296-8" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 66 "formatos" => array:2 [ "HTML" => 36 "PDF" => 30 ] ] "es" => array:12 [ "idiomaDefecto" => true "cabecera" => "Pros y Contras" "titulo" => "La insuficiencia cardiaca con fracción de eyección en rango intermedio ¿es similar a la de fracción de eyección preservada? A favor" "tienePdf" => "es" "tieneTextoCompleto" => "es" "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "296" "paginaFinal" => "298" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Is heart failure with midrange ejection fraction similar to preserved ejection fraction? For" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "M. Camafort Babkowski" "autores" => array:1 [ 0 => array:2 [ "nombre" => "M." "apellidos" => "Camafort Babkowski" ] ] ] ] ] "idiomaDefecto" => "es" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S2254887417300346" "doi" => "10.1016/j.rceng.2017.01.003" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2254887417300346?idApp=WRCEE" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0014256517300553?idApp=WRCEE" "url" => "/00142565/0000021700000005/v1_201705300032/S0014256517300553/v1_201705300032/es/main.assets" ] ] "itemSiguiente" => array:19 [ "pii" => "S2254887417300450" "issn" => "22548874" "doi" => "10.1016/j.rceng.2017.01.005" "estado" => "S300" "fechaPublicacion" => "2017-06-01" "aid" => "1367" "copyright" => "Elsevier España, S.L.U. and Sociedad Española de Medicina Interna (SEMI)" "documento" => "article" "crossmark" => 1 "subdocumento" => "fla" "cita" => "Rev Clin Esp. 2017;217:299-301" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 2 "PDF" => 2 ] "en" => array:12 [ "idiomaDefecto" => true "cabecera" => "PROS AND CONS" "titulo" => "Is heart failure with midrange ejection fraction similar to preserved ejection fraction? Against" "tienePdf" => "en" "tieneTextoCompleto" => "en" "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "299" "paginaFinal" => "301" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "La insuficiencia cardiaca con fracción de eyección en rango intermedio ¿es similar a la de fracción de eyección preservada? En contra" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "F. Formiga" "autores" => array:1 [ 0 => array:2 [ "nombre" => "F." "apellidos" => "Formiga" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0014256517300541" "doi" => "10.1016/j.rce.2017.01.012" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0014256517300541?idApp=WRCEE" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2254887417300450?idApp=WRCEE" "url" => "/22548874/0000021700000005/v1_201705300028/S2254887417300450/v1_201705300028/en/main.assets" ] "itemAnterior" => array:19 [ "pii" => "S2254887417300115" "issn" => "22548874" "doi" => "10.1016/j.rceng.2016.12.008" "estado" => "S300" "fechaPublicacion" => "2017-06-01" "aid" => "1353" "copyright" => "Elsevier España, S.L.U. and Sociedad Española de Medicina Interna (SEMI)" "documento" => "article" "crossmark" => 1 "subdocumento" => "ssu" "cita" => "Rev Clin Esp. 2017;217:289-95" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 3 "PDF" => 3 ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "Symposium. Polypathology" "titulo" => "Polypathology, polypharmacy, medication regimen complexity and drug therapy appropriateness" "tienePdf" => "en" "tieneTextoCompleto" => "en" "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "289" "paginaFinal" => "295" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Pluripatología, polifarmacia, complejidad terapéutica y uso adecuado de la medicación" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 698 "Ancho" => 1658 "Tamanyo" => 49235 ] ] "descripcion" => array:1 [ "en" => "Example of prescription cascade." ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "N. Gómez Aguirre, A. Caudevilla Martínez, L. Bellostas Muñoz, M. Crespo Avellana, J. Velilla Marco, J. Díez-Manglano" "autores" => array:6 [ 0 => array:2 [ "nombre" => "N." "apellidos" => "Gómez Aguirre" ] 1 => array:2 [ "nombre" => "A." "apellidos" => "Caudevilla Martínez" ] 2 => array:2 [ "nombre" => "L." "apellidos" => "Bellostas Muñoz" ] 3 => array:2 [ "nombre" => "M." "apellidos" => "Crespo Avellana" ] 4 => array:2 [ "nombre" => "J." "apellidos" => "Velilla Marco" ] 5 => array:2 [ "nombre" => "J." "apellidos" => "Díez-Manglano" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0014256517300267" "doi" => "10.1016/j.rce.2016.12.013" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0014256517300267?idApp=WRCEE" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2254887417300115?idApp=WRCEE" "url" => "/22548874/0000021700000005/v1_201705300028/S2254887417300115/v1_201705300028/en/main.assets" ] "en" => array:18 [ "idiomaDefecto" => true "cabecera" => "PROS AND CONS" "titulo" => "Is heart failure with midrange ejection fraction similar to preserved ejection fraction? In favor" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "296" "paginaFinal" => "298" ] ] "autores" => array:1 [ 0 => array:3 [ "autoresLista" => "M. Camafort Babkowski" "autores" => array:1 [ 0 => array:3 [ "nombre" => "M." "apellidos" => "Camafort Babkowski" "email" => array:1 [ 0 => "camafort@ub.edu" ] ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Servicio de Medicina Interna General, ICMiD Hospital Clínic-IDIBAPS, Universidad de Barcelona, Barcelona, Spain" "identificador" => "aff0005" ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "La insuficiencia cardiaca con fracción de eyección en rango intermedio ¿es similar a la de fracción de eyección preservada? A favor" ] ] "textoCompleto" => "The differentiation of patients with HF based on LVEF echocardiographic values is important due mainly to the fact that it helps establish 2 subtypes: HF with reduced LVEF (<40%) (HFrEF) and HF with preserved LVEF (≥50%) (HFpEF).<a class="elsevierStyleCrossRef" href="#bib0045">1</a> The 2 conditions are differentiated in terms of demographic characteristics, etiological factors, associated comorbidities and treatment.<a class="elsevierStyleCrossRef" href="#bib0045">1</a> Patients with HFrEF are younger and have fewer comorbidities, and their fundamental etiology is ischemic heart disease. Historically, most studies designed to treat HF have focused on patients with HFrEF, with most clinical trials excluding those patients with HFpEF. Therefore, most of the therapeutic evidence (both pharmaceutical and nonpharmaceutical) has been generated from patients with a LVEF typically <35–40%.<a class="elsevierStyleCrossRefs" href="#bib0050">2,3</a>Recently, the European Society of Cardiology has established a new category in the classification of HF based on LVEF.<a class="elsevierStyleCrossRef" href="#bib0055">3</a> This new category is known as HF with mid-range EF (HFmEF) and encompasses all patients with LVEF between 40% and 49%, which until now constituted an undefined “gray area”.<a class="elsevierStyleCrossRef" href="#bib0060">4</a> As with HFpEF, the evidence on its treatment is highly limited. Although this new category currently represents no more than 10%,<a class="elsevierStyleCrossRef" href="#bib0065">5</a> the improvements in treating ischemic heart disease will increasingly lead to more patients with ischemia presenting less myocardial damage, increasing the percentage of those with HFmEF.<a class="elsevierStyleCrossRef" href="#bib0060">4</a>The patterns of the various types of HF have varying characteristics. Thus, patients with HFrEF have primary and symptomatic heart disease as the leading cause of their HF, while those with HFpEF have multiorgan disease in which various phases occur, symptomatic or not.<a class="elsevierStyleCrossRef" href="#bib0055">3</a> Therefore, when establishing whether there are similarities between HFmEF and HFpEF, we need other data (in addition to LVEF) such as natriuretic peptide levels, renal function and comorbidity data that help us make comparisons.A study performed on 1663 patients with HF (of hypertensive, ischemic or idiopathic origin) assessed the presence of left ventricular dysfunction in each of the 3 HF categories (based on their LVEF).<a class="elsevierStyleCrossRef" href="#bib0070">6</a> Sixty-seven percent of the patients had HFrEF, 23% had HFpEF, and the remaining 10% had HFmEF. In terms of the differential characteristics between the various types of HF, the study observed that the patients with HFmEF had a systolic and diastolic blood pressure and a prevalence of atrial fibrillation similar to those with preserved LVEF. Compared with the HFrEF group, the patients with HFpEF and HFmEF had a lower percentage of cases in functional classes III and IV, lower serum BNP concentrations, lower right ventricular dysfunction (defined as tricuspid annular plane systolic excursion [TAPSE] <14%) and a lower percentage of patients with systolic pulmonary artery pressure >40mmHg.<a class="elsevierStyleCrossRef" href="#bib0070">6</a> Unlike the HFpEF group, the patients with HFmEF had more ischemic heart disease; were more frequently treated with angiotensin-converting enzyme inhibitors, angiotensin II receptor antagonists, beta-blockers and spironolactone and had a greater rate of device implantation.<a class="elsevierStyleCrossRef" href="#bib0070">6</a>In another recent study, Kapoor et al. analyzed a total of 99,825 patients with HF who were hospitalized in 305 centers in the United States from 2005 to 2013.<a class="elsevierStyleCrossRef" href="#bib0075">7</a> Forty-nine percent of the patients were classified as HFrEF, 13% as HFmEF and 38% as HFpEF. The patients with HFmEF had a similar age, sex and comorbidities to those of patients with HFpEF (older, percentage of women and number of comorbidities). However, the HFmEF group had ischemic heart disease as the fundamental cause, similar to the HFrEF group.Another aspect to consider is that patients with HFmEF do not constitute a homogeneous group because, depending on the pathophysiological mechanism, the LVEF can be the result of the recovery of previously reduced systolic function or the result of a systolic function impairment that achieves mid-range LVEF readings.<a class="elsevierStyleCrossRef" href="#bib0080">8</a> A recent study observed that patients with recovered HFmEF had fewer cardiovascular events, as did those who had HFpEF. Nevertheless, this patient group with recovered HFmEF showed biological, epidemiological and echocardiographic characteristics different from those of the other HFpEF and HFrEF groups and could therefore constitute a type with its own identity.<a class="elsevierStyleCrossRef" href="#bib0080">8</a> Nevertheless, one of the main criticisms of this article would be that the authors define HFpEF starting from an LVEF ≥55%. This aspect impedes the differentiation between HFmEF and HFpEF, because a consensus has still not been reached on what constitutes the normal value for LVEF.<a class="elsevierStyleCrossRef" href="#bib0055">3</a>In summary, given that normal LVEF values have not been defined and considering the pathophysiological mechanisms and clinical progression, we can conclude that HFmEF is probably similar to HFpEF. Nevertheless, the evidence is still limited for reaching a definitive conclusion on this fascinating dilemma.Conflicts of interestThe authors declare that they have no conflicts of interest." "textoCompletoSecciones" => array:1 [ "secciones" => array:6 [ 0 => array:3 [ "identificador" => "xres844949" "titulo" => "Abstract" "secciones" => array:1 [ 0 => array:1 [ "identificador" => "abst0005" ] ] ] 1 => array:2 [ "identificador" => "xpalclavsec839875" "titulo" => "Keywords" ] 2 => array:3 [ "identificador" => "xres844948" "titulo" => "Resumen" "secciones" => array:1 [ 0 => array:1 [ "identificador" => "abst0010" ] ] ] 3 => array:2 [ "identificador" => "xpalclavsec839874" "titulo" => "Palabras clave" ] 4 => array:2 [ "identificador" => "sec0005" "titulo" => "Conflicts of interest" ] 5 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2016-12-19" "fechaAceptado" => "2017-01-22" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec839875" "palabras" => array:3 [ 0 => "Heart failure" 1 => "Diastolic dysfunction" 2 => "Left ventricular ejection fraction" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec839874" "palabras" => array:3 [ 0 => "Insuficiencia cardiaca" 1 => "Disfunción diastólica" 2 => "Fracción de eyección de ventrículo izquierdo" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "Basing heart failure (HF) classification on the echocardiographic values of left ventricular ejection fraction (LVEF) has been useful in defining two sub-types of HF:HF with reduced LVEF and HF with preserved LVEF. A new category has recently been defined: HF with midrange LVEF (40–49%). When current information is taken into account, this new category is more similar to HF with preserved LVEF than reduced LVEF." ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "La clasificación de la insuficiencia cardiaca (IC) basada en los valores ecocardiográficos de la fracción de eyección del ventrículo izquierdo (FEVI) ha sido útil para definir 2 subtipos de IC: con FEVI reducida y con FEVI preservada. Recientemente se ha definido una nueva categoría, denominada IC con FEVI en rango medio (40-49%), que teniendo en cuenta la información disponible hasta el momento, posee más similitudes con la IC y FEVI preservada que reducida. No obstante, la evidencia aún es limitada para que la conclusión sea definitiva." ] ] "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "Please cite this article as: Camafort Babkowski M. La insuficiencia cardiaca con fracción de eyección en rango intermedio ¿es similar a la de fracción de eyección preservada? A favor. Rev Clin Esp. 2017;217:296–298." ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:8 [ 0 => array:3 [ "identificador" => "bib0045" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "What have we learned about patients with heart failure and preserved ejection fraction from DIG-PEF, CHARM-preserved, and I-PRESERVE" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "R.T. Campbell" 1 => "P.S. Jhund" 2 => "D. Castagno" 3 => "N.M. Hawkins" 4 => "M.C. Petrie" 5 => "J.J. McMurray" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.jacc.2012.04.064" "Revista" => array:6 [ "tituloSerie" => "J Am Coll Cardiol" "fecha" => "2012" "volumen" => "60" "paginaInicial" => "2349" "paginaFinal" => "2356" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23141494" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0050" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "2013 ACCF/AHA guideline for the management of heart failure: a report of the American College of Cardiology Foundation/American Heart Association task force on practice guidelines" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "C.W. Yancy" 1 => "M. Jessup" 2 => "B. Bozkurt" 3 => "J. Butler" 4 => "D.E. Casey" 5 => "M.H. Drazner" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1161/CIR.0b013e31829e8776" "Revista" => array:6 [ "tituloSerie" => "Circulation" "fecha" => "2013" "volumen" => "128" "paginaInicial" => "e240" "paginaFinal" => "e327" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23741058" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0055" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "P. Ponikowski" 1 => "A.A. Voors" 2 => "S.D. Anker" 3 => "H. Bueno" 4 => "J.G.F. Cleland" 5 => "A.J.S. Coats" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1093/eurheartj/ehw128" "Revista" => array:6 [ "tituloSerie" => "Eur Heart J" "fecha" => "2016" "volumen" => "37" "paginaInicial" => "2129" "paginaFinal" => "2200" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/27206819" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0060" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Heart failure with mid-range ejection fraction-new opportunities" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "L.H. Lund" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.cardfail.2016.07.439" "Revista" => array:6 [ "tituloSerie" => "J Card Fail" "fecha" => "2016" "volumen" => "22" "paginaInicial" => "769" "paginaFinal" => "771" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/27469481" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0065" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The middle child in heart failure: heart failure with mid-range ejection fraction (40–50%)" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "C.S.P. Lam" 1 => "S.D. Solomon" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1002/ejhf.159" "Revista" => array:6 [ "tituloSerie" => "Eur J Heart Fail" "fecha" => "2014" "volumen" => "16" "paginaInicial" => "1049" "paginaFinal" => "1055" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25210008" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0070" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Different correlates but similar prognostic implications for right ventricular dysfunction in heart failure patients with reduced or preserved ejection fraction" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "S. Ghio" 1 => "M. Guazzi" 2 => "A.B. Scardovi" 3 => "C. Klersy" 4 => "F. Clemenza" 5 => "E. Carluccio" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1002/ejhf.664" "Revista" => array:2 [ "tituloSerie" => "Eur J Heart Fail" "fecha" => "2016" ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0075" "etiqueta" => "7" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Precipitating clinical factors, heart failure characterization, and outcomes in patients hospitalized with heart failure with reduced, borderline, and preserved ejection fraction" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "J.R. Kapoor" 1 => "R. Kapoor" 2 => "C. Ju" 3 => "P.A. Heidenreich" 4 => "Z.J. Eapen" 5 => "A.F. Hernandez" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.jchf.2016.02.017" "Revista" => array:6 [ "tituloSerie" => "JACC Heart Fail" "fecha" => "2016" "volumen" => "4" "paginaInicial" => "464" "paginaFinal" => "472" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/27256749" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib0080" "etiqueta" => "8" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Heart failure and midrange ejection fraction: implications of recovered ejection fraction for exercise tolerance and outcomes" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "W. Nadruz" 1 => "E. West" 2 => "M. Santos" 3 => "H. Skali" 4 => "J.D. Groarke" 5 => "D.E. Forman" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1161/CIRCHEARTFAILURE.115.002826" "Revista" => array:5 [ "tituloSerie" => "Circ Heart Fail" "fecha" => "2016" "volumen" => "9" "paginaInicial" => "e002826" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/27009553" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/22548874/0000021700000005/v1_201705300028/S2254887417300346/v1_201705300028/en/main.assets" "Apartado" => array:4 [ "identificador" => "66381" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Pros and cons" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/22548874/0000021700000005/v1_201705300028/S2254887417300346/v1_201705300028/en/main.pdf?idApp=WRCEE&text.app=https://revclinesp.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2254887417300346?idApp=WRCEE"]

Revista Clínica Española (English Edition)

ISSN: 2254-8874

Revista Clínica Española published its first issue in 1940 and is the body of expression of the Spanish Society of Internal Medicine (SEMI).
The journal fully endorses the goals of updating knowledge and facilitating the acquisition of key developments in internal medicine applied to clinical practice. Revista Clínica Española is subject to a thorough double blind review of the received articles written in Spanish or English. Ten issues are published each year, including mostly originals, reviews and consensus documents.

Indexed in:

Current Contents / Clinical Medicine , JCR / SCI-Expanded, Index Medicus / Medline y Excerpta Medica / EMBASE

Subscribe:

Impact factor

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years.

© Clarivate Analytics, Journal Citation Reports 2022

Impact factor 2023

2.3

Citescore

CiteScore measures average citations received per document published.

Citescore 2023

0.7

SJR

SRJ is a prestige metric based on the idea that not all citations are the same. SJR uses a similar algorithm as the Google page rank; it provides a quantitative and qualitative measure of the journal's impact.

SJR 2023

0.162

SNIP

SNIP measures contextual citation impact by wighting citations based on the total number of citations in a subject field.

SNIP 2023

0.211

View more metrics

Open Access Option

Journal Information

Previous article | Next article

Lee este artículo en Español

Export reference

Download PDF

Purchase article

For the purchase of this article it is necessary to fill in the following form:

Name *

First surname *

Second surname

Email *

Address *

Number *

City *

Afganistan

Albania

Alemania

Andorra

Angola

Anguilla

Antartica

Antigua and barbuda

Antillas holandesas

Arabia saudita

Argelia

Argentina

Armenia

Aruba

Australia

Austria

Azerbaijan

Bahamas

Bahrain

Bangladesh

Barbados

Belarus

Belgica

Belice

Benin

Bermudas/antillas britanicas

Bhutan

Bolivia

Bosnia y herzegowina

Botswana

Brasil

Brunei darussalam

Bulgaria

Burkina faso

Burundi

Cabo verde

Camboya

Camerun

Canada

Chad

Chile

China

Chipre

Colombia

Comoros

Corea

Costa rica

Cote d´ivoire

Croacia

Cuba

Dinamarca

Djibouti

Dominica

East timor

Ecuador

Egipto

El salvador

Emiratos arabes unidos

Eritrea

Escocia

Eslovaquia

Eslovenia

España

Estados federados de micronesia

Estados unidos

Estonia

Etiopia

Fiji

Filipinas

Finlandia

Francia

Gabon

Gambia

Georgia

Ghana

Gibraltar

Grecia

Grenada

Groenlandia

Guadalupe

Guam

Guatemala

Guayana britanica

Guinea

Guinea ecuatorial

Guinea francesa

Guinea-bissau

Haiti

Holanda

Honduras

Hong kong

Hungria

India

Indonesia

Irak

Iran

Irlanda

Isla bouvet

Isla cocos (keeling)

Isla cook

Isla mauricio

Isla navidad

Isla norfolk

Islandia

Islas caiman

Islas falkland (malvinas)

Islas faroe

Islas georgia del sur y sandwich

Islas heard and mc donald

Islas marshall

Islas northern mariana

Islas salomon

Islas svalbard and jan mayen

Islas turks and caicos

Islas united states minor outlyi

Islas virgenes (britanicas)

Islas virgenes (u.s.a.)

Islas wallis and futuna

Israel

Italia

Jamaica

Japon

Jordania

Kazakhstan

Kenia

Kiribati

Kuwait

Kyrgyzstan

Lesoto

Letonia

Libano

Liberia

Libia arab jamahiriya

Liechtenstein

Lituania

Luxemburgo

Macao

Macedonia

Madagascar

Malasia

Malawi

Maldives

Mali

Malta

Marruecos

Martinica

Mauritania

Mayotte

Mexico

Monaco

Mongolia

Monserrat

Morocco

Mozambique

Myanmar

Namibia

Nauru

Nepal

Nicaragua

Niger

Nigeria

Niue

Noruega

Nueva caledonia

Nueva zelanda

Oman

Pakistan

Palau

Panama

Papua new guinea

Paraguay

Peru

Pitcairn

Polinesia francesa

Polonia

Portugal

Posesiones gran bretaña

Posesiones u.s.a.

Puerto rico

Qatar

Reino unido

Republica checa

Republica de africa central

Republica de cabo verde

Republica de congo

Republica de corea

Republica de moldova

Republica democratica de laos

Republica democratica del congo

Republica dominicana

Reunion

Ruanda

Rumania

Rusia

Sahara occidental

Saint kitts and nevis

Samoa

Samoa americana

San marino

San tomas y principe

San vincent and the grenadines

Santa lucia

Senegal

Serbia

Seychelles

Sierra leona

Singapur

Siria

Somalia

Sri lanka

St. helena

St. pierre and miquelon

Sudafrica

Sudan

Suecia

Suiza

Surinam

Swaziland

Tailandia

Taiwan republica de china

Tajikistan

Tanzania

Territorio de indias britanicas

Togo

Tokelau

Tonga

Trinidad and tobago

Tunisia

Turkmenistan

Turquia

Tuvalu

Ucrania

Uganda

Uruguay

Uzbekistan

Vanuatu

Vaticano

Venezuela

Vietnam

Yemen

Yugoslavia

Zambia

Zimbawe

Lebanon

Paises bajos

A coruña

Alava

Albacete

Alicante

Almeria

Asturias

Avila

Badajoz

Balears

Barcelona

Bizkaia

Burgos

Caceres

Cadiz

Cantabria

Castellon

Ceuta

Ciudad real

Cordoba

Cuenca

Girona

Granada

Guadalajara

Guipuzcoa

Huelva

Huesca

Jaen

La rioja

Las palmas

Leon

Lleida

Lugo

Madrid

Malaga

Melilla

Murcia

Navarra

Ourense

Palencia

Pontevedra

Salamanca

Segovia

Sevilla

Soria

Tarragona

Tenerife

Teruel

Toledo

Valencia

Valladolid

Zamora

Zaragoza

-- Not applicable --

Código postal *

Phone *

NIF o número identificativo *

I accept to receive information about Elsevier's special products and promotions by email

I accept to receive information about products and special promotions from Elsevier partners by email

I have read and understand the Privacy Policy and Terms and conditions and agree to be bound by all of its terms.

* Required fields

In addition to temporary access to the article, it will be sent by email.

Customer Support

Phone

Calls from Spain

932 415 960

Calls from abroad

+34 932 415 960

Hours from 9 a.m. to 6 p.m. except the months of July and August, which will be from 9 am to 3 pm.

Highlighted articles

Recommendations of the Spanish-Portuguese Internal Medicine services in the fight against climate change and environmental degradation

Publish in

Revista Clínica Española

Free access articles

The value of multi-modal ultrasound in the assessment of...

Rev Clin Esp. 2024;224:437-44

Adverse cardiovascular, obstetric and perinatal events...

Rev Clin Esp. 2024;224:337-45

How to detect non-institutionalized older patients at risk...

Rev Clin Esp. 2024;224:217-24

Revista Clínica Española (English Edition) is a member and subscribes the principles of, the Committee on Publication Ethics (COPE)
www.publicationethics.org.

Indexed in:

Follow us:

Subscribe:

Purchase article

Subscribe to our newsletter