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        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Background</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Patients with heart failure &#40;HF&#41; and chronic obstructive pulmonary disease &#40;COPD&#41; have a high risk of hospital admission and mortality&#46; This study evaluated the benefit of a care model&#44; characterized by comprehensive and continuous care &#40;UMIPIC program&#41; in patients with HF and a history of COPD&#46;</p></span> <span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Methods</span><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">A total of 5644 patients were prospectively recruited&#44; of which 1320 had a history of COPD between March 2008 and March 2020&#46; They were divided into 2 follow-up groups at the time of discharge&#44; one in follow-up in the UMIPIC program &#40;435 patients&#41; and another treated conventionally &#40;885 patients&#41;&#46; The baseline characteristics of each group were analyzed and patients in each group were selected by propensity score matching and admissions and mortality were evaluated during 12 months of follow-up&#44; after an episode of hospitalization for HF&#46;</p></span> <span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Results</span><p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">The UMIPIC group&#44; compared to the conventional group in the matched cohort&#44; had a lower rate of admissions for HF &#40;21&#37; vs 30 respectively&#59; hazard ratio &#91;HR&#93;&#8201;&#61;&#8201;0&#46;64&#59; 95&#37; confidence interval &#91;95&#37; CI&#93;&#58; 0&#46;54-0&#46;84&#59; p&#8201;&#61;&#8201;0&#46;002&#41; and mortality &#40;28&#37; vs&#46; 36&#37;&#44; respectively&#59; HR&#8201;&#61;&#8201;0&#46;68&#59; 95&#37; CI&#58; 0&#46;51-0&#46;90&#59; p&#8201;&#61;&#8201;0&#46;008&#41;&#46; From a therapeutic point of view&#44; patients with HF and a history of COPD who were followed in the UMIPIC program received a higher percentage of beta-blockers &#40;64&#37; vs 54&#37;&#59; p&#8201;&#60;&#8201;0&#46;05&#41; and direct-acting anticoagulants &#40;17&#37; vs 9&#37;&#58; p&#8201;&#60;&#8201;0&#46;05&#41; than those followed conventionally&#46;</p></span> <span id="abst0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Conclusions</span><p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">The implementation of the UMIPIC care program for patients with HF and a history of COPD&#44; based on comprehensive and continuous care&#44; reduces both admissions and mortality at one year of follow-up&#46; The prescription of beta-blockers and direct-acting anticoagulants was also higher during follow-up in the UMIPIC program&#46;</p></span>"
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        "resumen" => "<span id="abst0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Antecedentes</span><p id="spar0060" class="elsevierStyleSimplePara elsevierViewall">Los pacientes con insuficiencia card&#237;aca &#40;IC&#41; y enfermedad pulmonar obstructiva cr&#243;nica &#40;EPOC&#41; presentan un riesgo elevado de ingreso hospitalario y mortalidad&#46; En este estudio se evalu&#243; el beneficio de un modelo asistencial&#44; caracterizado por una atenci&#243;n integral y continuada &#40;programa UMIPIC&#41; en pacientes con IC y antecedentes de EPOC&#46;</p></span> <span id="abst0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">M&#233;todos</span><p id="spar0065" class="elsevierStyleSimplePara elsevierViewall">Se reclutaron prospectivamente un total de 5644 pacientes&#44; de los cuales 1320 tuvieron antecedentes de EPOC entre marzo de 2008 y marzo de 2020&#46; Se dividieron en 2 grupos de seguimiento en el momento del alta&#44; uno en seguimiento en el programa UMIPIC &#40;435 pacientes&#41; y otro atendido de forma convencional &#40;885 pacientes&#41;&#46; Se analizaron las caracter&#237;sticas basales de cada grupo y se seleccionaron por emparejamiento &#40;<span class="elsevierStyleItalic">propensity score matching&#41;</span> pacientes en cada grupo y se evaluaron los ingresos y la mortalidad durante 12 meses de seguimiento&#44; tras un episodio de hospitalizaci&#243;n por IC&#46;</p></span> <span id="abst0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Resultados</span><p id="spar0070" class="elsevierStyleSimplePara elsevierViewall">El grupo UMIPIC&#44; con respecto al convencional en la cohorte emparejada&#44; tuvo una menor tasa de ingresos por IC &#40;21&#37; frente a 30 respectivamente&#59; <span class="elsevierStyleItalic">hazard ratio</span> &#91;HR&#93;&#8201;&#61;&#8201;0&#44;64&#59; intervalo de confianza del 95&#37; &#91;IC 95&#37;&#93;&#58; 0&#44;54-0&#44;84&#59; p&#8201;&#61;&#8201;0&#46;002&#41; y de mortalidad &#40;28&#37; frente a 36&#37;&#44; respectivamente&#59; HR&#8201;&#61;&#8201;0&#44;68&#59; IC 95&#37;&#58; 0&#44;51-0&#44;90&#59; p&#8201;&#61;&#8201;0&#44;008&#41;&#46; Desde el punto de vista terap&#233;utico los pacientes con IC y antecedentes de EPOC que fueron seguidos en el programa UMIPIC recibieron en mayor porcentaje betabloqueantes &#40;63&#46;9&#37; vs 54&#46;2&#37;&#59; p&#8201;&#60;&#8201;0&#46;05&#41; y de anticoagulantes de acci&#243;n directa &#40;17&#37; vs 9&#37;&#58; p&#8201;&#60;&#8201;0&#46;05&#41; que los seguidos de forma convencional&#46;</p></span> <span id="abst0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Conclusiones</span><p id="spar0075" class="elsevierStyleSimplePara elsevierViewall">La implementaci&#243;n del programa asistencial UMIPIC a pacientes con IC y antecedentes de EPOC&#44; basado en una atenci&#243;n integral y continuada&#44; reduce tanto los ingresos como la mortalidad al a&#241;o de seguimiento&#46; La prescripci&#243;n de betabloqueantes y anticoagulantes de acci&#243;n directa tambi&#233;n fue mayor durante el seguimiento en el programa UMIPIC&#46;</p></span>"
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Original article
Pre-proof, online 28 October 2024
Benefits of a comprehensive care model in patients with heart failure and chronic obstructive pulmonary disease: UMIPIC Program
Beneficios de un modelo asistencial integral en pacientes con insuficiencia cardíaca y enfermedad pulmonar obstructiva crónica: Programa UMIPIC
Manuel Méndez Bailóna,
Corresponding author
manuel.mendez@salud.madrid.org

Corresponding author.
, Álvaro González-Francob, José M. Cerqueiroc, José Pérez-Silvestred, Carmen Moreno Garcíae, Alicia Conde-Martelf, José Carlos Arévalo-Loridog, Francesc Formiga Pérezh, Luis Manzano-Espinosai,1, Manuel Montero-Pérez-Barqueroj,1
a Servicio de Medicina Interna, Hospital Clínico San Carlos, Facultad de Medicina, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Hospital Clínico San Carlos (IDISSC), Madrid, Spain
b Servicio de Medicina Interna, Hospital Universitario Central de Asturias, Oviedo, Asturias, Spain
c Servicio de Medicina Interna, Hospital Universitario Lucus Augusti, Lugo, Spain
d Servicio de Medicina Interna, Consorcio Hospital General Universitario de Valencia, Valencia, Spain
e Servicio de Medicina Interna, Hospital de Manises, Valencia, Spain
f Servicio de Medicina Interna, Hospital Universitario de Gran Canaria Dr Negrín, Gran Canaria, Spain
g Medicina Interna, Hospital Universitario de Badajoz, Badajoz, Spain
h Servicio de Medicina Interna. Hospital Universitario de Bellvitge, Barcelona, Spain
i Servicio de Medicina Interna, Instituto Ramón y Cajal de Investigación Sanitaria, Hospital Universitario Ramón y Cajal, Universidad de Alcalá, Madrid, Spain
j Instituto Maimónides de Investigación Biomédica, Hospital Universitario Reina Sofía, Córdoba, Spain
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