Suscríbase a la Revista
Búsqueda avanzada
 array:24 [
  "pii" => "S0014256516300819"
  "issn" => "00142565"
  "doi" => "10.1016/j.rce.2016.05.008"
  "estado" => "S300"
  "fechaPublicacion" => "2016-10-01"
  "aid" => "1283"
  "copyright" => "Elsevier España, S.L.U. and Sociedad Española de Medicina Interna (SEMI)"
  "copyrightAnyo" => "2016"
  "documento" => "article"
  "crossmark" => 1
  "subdocumento" => "fla"
  "cita" => "Rev Clin Esp. 2016;216:345-51"
  "abierto" => array:3 [
    "ES" => false
    "ES2" => false
    "LATM" => false
  ]
  "gratuito" => false
  "lecturas" => array:2 [
    "total" => 119
    "formatos" => array:2 [
      "HTML" => 80
      "PDF" => 39
    ]
  ]
  "Traduccion" => array:1 [
    "en" => array:19 [
      "pii" => "S2254887416300340"
      "issn" => "22548874"
      "doi" => "10.1016/j.rceng.2016.05.002"
      "estado" => "S300"
      "fechaPublicacion" => "2016-10-01"
      "aid" => "1283"
      "copyright" => "Elsevier España, S.L.U. and Sociedad Española de Medicina Interna (SEMI)"
      "documento" => "article"
      "crossmark" => 1
      "subdocumento" => "fla"
      "cita" => "Rev Clin Esp. 2016;216:345-51"
      "abierto" => array:3 [
        "ES" => false
        "ES2" => false
        "LATM" => false
      ]
      "gratuito" => false
      "lecturas" => array:2 [
        "total" => 2
        "PDF" => 2
      ]
      "en" => array:13 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Original article</span>"
        "titulo" => "Stroke in young adults&#58; Incidence rate&#44; risk factors&#44; treatment and prognosis"
        "tienePdf" => "en"
        "tieneTextoCompleto" => "en"
        "tieneResumen" => array:2 [
          0 => "en"
          1 => "es"
        ]
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "345"
            "paginaFinal" => "351"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "es" => array:1 [
            "titulo" => "Ictus en adultos j&#243;venes&#58; incidencia&#44; factores de riesgo&#44; tratamiento y pron&#243;stico"
          ]
        ]
        "contieneResumen" => array:2 [
          "en" => true
          "es" => true
        ]
        "contieneTextoCompleto" => array:1 [
          "en" => true
        ]
        "contienePdf" => array:1 [
          "en" => true
        ]
        "resumenGrafico" => array:2 [
          "original" => 0
          "multimedia" => array:7 [
            "identificador" => "fig0005"
            "etiqueta" => "Figure 1"
            "tipo" => "MULTIMEDIAFIGURA"
            "mostrarFloat" => true
            "mostrarDisplay" => false
            "figura" => array:1 [
              0 => array:4 [
                "imagen" => "gr1.jpeg"
                "Alto" => 889
                "Ancho" => 1576
                "Tamanyo" => 77590
              ]
            ]
            "descripcion" => array:1 [
              "en" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Number of stroke cases per age group&#46;</p>"
            ]
          ]
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "F&#46;J&#46; Gonz&#225;lez-G&#243;mez, P&#46; P&#233;rez-Torre, A&#46; De-Felipe, R&#46; Vera, C&#46; Matute, A&#46; Cruz-Culebras, R&#46; &#193;lvarez-Velasco, J&#46; Masjuan"
            "autores" => array:8 [
              0 => array:2 [
                "nombre" => "F&#46;J&#46;"
                "apellidos" => "Gonz&#225;lez-G&#243;mez"
              ]
              1 => array:2 [
                "nombre" => "P&#46;"
                "apellidos" => "P&#233;rez-Torre"
              ]
              2 => array:2 [
                "nombre" => "A&#46;"
                "apellidos" => "De-Felipe"
              ]
              3 => array:2 [
                "nombre" => "R&#46;"
                "apellidos" => "Vera"
              ]
              4 => array:2 [
                "nombre" => "C&#46;"
                "apellidos" => "Matute"
              ]
              5 => array:2 [
                "nombre" => "A&#46;"
                "apellidos" => "Cruz-Culebras"
              ]
              6 => array:2 [
                "nombre" => "R&#46;"
                "apellidos" => "&#193;lvarez-Velasco"
              ]
              7 => array:2 [
                "nombre" => "J&#46;"
                "apellidos" => "Masjuan"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "en"
      "Traduccion" => array:1 [
        "es" => array:9 [
          "pii" => "S0014256516300819"
          "doi" => "10.1016/j.rce.2016.05.008"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => false
            "ES2" => false
            "LATM" => false
          ]
          "gratuito" => false
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "es"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0014256516300819?idApp=WRCEE"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2254887416300340?idApp=WRCEE"
      "url" => "/22548874/0000021600000007/v2_201704020050/S2254887416300340/v2_201704020050/en/main.assets"
    ]
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S0014256516300790"
    "issn" => "00142565"
    "doi" => "10.1016/j.rce.2016.05.006"
    "estado" => "S300"
    "fechaPublicacion" => "2016-10-01"
    "aid" => "1281"
    "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;U&#46; and Sociedad Espa&#241;ola de Medicina Interna &#40;SEMI&#41;"
    "documento" => "article"
    "crossmark" => 1
    "subdocumento" => "fla"
    "cita" => "Rev Clin Esp. 2016;216:352-60"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 107
      "formatos" => array:2 [
        "HTML" => 73
        "PDF" => 34
      ]
    ]
    "es" => array:13 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">ORIGINAL</span>"
      "titulo" => "Efecto de una intervenci&#243;n sobre indicadores de calidad para mejorar el tratamiento de la hiperglucemia en pacientes hospitalizados en &#225;reas no cr&#237;ticas"
      "tienePdf" => "es"
      "tieneTextoCompleto" => "es"
      "tieneResumen" => array:2 [
        0 => "es"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "352"
          "paginaFinal" => "360"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Effect of an intervention on quality indicators for improving the treatment of hyperglycemia in patients hospitalized in noncritical areas"
        ]
      ]
      "contieneResumen" => array:2 [
        "es" => true
        "en" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "es" => true
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0005"
          "etiqueta" => "Figura 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 837
              "Ancho" => 1380
              "Tamanyo" => 79317
            ]
          ]
          "descripcion" => array:1 [
            "es" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Perfil de glucemia capilar en el grupo basal y en el grupo postintervenci&#243;n en las 24<span class="elsevierStyleHsp" style=""></span>h previas al estudio&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "J&#46; Ena, R&#46; G&#243;mez-Huelgas, A&#46; Zapatero-Gaviria, P&#46; V&#225;zquez-Rodriguez, C&#46; Gonz&#225;lez-Becerra, M&#46; Romero-S&#225;nchez, M&#46;J&#46; Ig&#250;zquiza-Pellejero, A&#46; Artero-Mora, J&#46;M&#46; Varela-Aguilar"
          "autores" => array:10 [
            0 => array:2 [
              "nombre" => "J&#46;"
              "apellidos" => "Ena"
            ]
            1 => array:2 [
              "nombre" => "R&#46;"
              "apellidos" => "G&#243;mez-Huelgas"
            ]
            2 => array:2 [
              "nombre" => "A&#46;"
              "apellidos" => "Zapatero-Gaviria"
            ]
            3 => array:2 [
              "nombre" => "P&#46;"
              "apellidos" => "V&#225;zquez-Rodriguez"
            ]
            4 => array:2 [
              "nombre" => "C&#46;"
              "apellidos" => "Gonz&#225;lez-Becerra"
            ]
            5 => array:2 [
              "nombre" => "M&#46;"
              "apellidos" => "Romero-S&#225;nchez"
            ]
            6 => array:2 [
              "nombre" => "M&#46;J&#46;"
              "apellidos" => "Ig&#250;zquiza-Pellejero"
            ]
            7 => array:2 [
              "nombre" => "A&#46;"
              "apellidos" => "Artero-Mora"
            ]
            8 => array:2 [
              "nombre" => "J&#46;M&#46;"
              "apellidos" => "Varela-Aguilar"
            ]
            9 => array:1 [
              "colaborador" => "en representaci&#243;n del Grupo de Estudio de Diabetes y Obesidad de la Sociedad Espa&#241;ola de Medicina Interna"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "Traduccion" => array:1 [
      "en" => array:9 [
        "pii" => "S2254887416300364"
        "doi" => "10.1016/j.rceng.2016.05.004"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => false
          "ES2" => false
          "LATM" => false
        ]
        "gratuito" => false
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "en"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2254887416300364?idApp=WRCEE"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0014256516300790?idApp=WRCEE"
    "url" => "/00142565/0000021600000007/v1_201609280158/S0014256516300790/v1_201609280158/es/main.assets"
  ]
  "asociados" => array:1 [
    0 => array:18 [
      "pii" => "S0014256516300972"
      "issn" => "00142565"
      "doi" => "10.1016/j.rce.2016.06.005"
      "estado" => "S300"
      "fechaPublicacion" => "2016-10-01"
      "aid" => "1292"
      "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;U&#46; and Sociedad Espa&#241;ola de Medicina Interna &#40;SEMI&#41;"
      "documento" => "simple-article"
      "crossmark" => 1
      "subdocumento" => "edi"
      "cita" => "Rev Clin Esp. 2016;216:367-9"
      "abierto" => array:3 [
        "ES" => false
        "ES2" => false
        "LATM" => false
      ]
      "gratuito" => false
      "lecturas" => array:2 [
        "total" => 36
        "formatos" => array:2 [
          "HTML" => 22
          "PDF" => 14
        ]
      ]
      "es" => array:10 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">EDITORIAL</span>"
        "titulo" => "De los factores psicol&#243;gicos que influyen en otras afecciones m&#233;dicas a los procesos psicosom&#225;ticos&#58; &#191;una lecci&#243;n olvidada&#63;"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "367"
            "paginaFinal" => "369"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "From psychological factors that influence other medical conditions to psychosomatic processes&#58; A forgotten lesson&#63;"
          ]
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "R&#46; Campos R&#243;denas"
            "autores" => array:1 [
              0 => array:2 [
                "nombre" => "R&#46;"
                "apellidos" => "Campos R&#243;denas"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0014256516300972?idApp=WRCEE"
      "url" => "/00142565/0000021600000007/v1_201609280158/S0014256516300972/v1_201609280158/es/main.assets"
    ]
  ]
  "es" => array:19 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">ORIGINAL</span>"
    "titulo" => "Ictus en adultos j&#243;venes&#58; incidencia&#44; factores de riesgo&#44; tratamiento y pron&#243;stico"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "345"
        "paginaFinal" => "351"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "F&#46;J&#46; Gonz&#225;lez-G&#243;mez, P&#46; P&#233;rez-Torre, A&#46; DeFelipe, R&#46; Vera, C&#46; Matute, A&#46; Cruz-Culebras, R&#46; &#193;lvarez-Velasco, J&#46; Masjuan"
        "autores" => array:8 [
          0 => array:4 [
            "nombre" => "F&#46;J&#46;"
            "apellidos" => "Gonz&#225;lez-G&#243;mez"
            "email" => array:1 [
              0 => "javiergonzalezneurologia&#64;gmail&#46;com"
            ]
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:2 [
            "nombre" => "P&#46;"
            "apellidos" => "P&#233;rez-Torre"
          ]
          2 => array:2 [
            "nombre" => "A&#46;"
            "apellidos" => "DeFelipe"
          ]
          3 => array:2 [
            "nombre" => "R&#46;"
            "apellidos" => "Vera"
          ]
          4 => array:2 [
            "nombre" => "C&#46;"
            "apellidos" => "Matute"
          ]
          5 => array:2 [
            "nombre" => "A&#46;"
            "apellidos" => "Cruz-Culebras"
          ]
          6 => array:2 [
            "nombre" => "R&#46;"
            "apellidos" => "&#193;lvarez-Velasco"
          ]
          7 => array:2 [
            "nombre" => "J&#46;"
            "apellidos" => "Masjuan"
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:2 [
            "entidad" => "Unidad de Ictus&#44; Servicio de Neurolog&#237;a&#44; Hospital Universitario Ram&#243;n y Cajal&#44; Instituto de Investigaci&#243;n IRYCIS&#44; Universidad de Alcal&#225; de Henares&#44; Madrid&#44; Espa&#241;a"
            "identificador" => "aff0005"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Autor para correspondencia&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "en" => array:1 [
        "titulo" => "Stroke in young adults&#58; Incidence rate&#44; risk factors&#44; treatment and prognosis"
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:7 [
        "identificador" => "fig0005"
        "etiqueta" => "Figura 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 883
            "Ancho" => 1576
            "Tamanyo" => 74843
          ]
        ]
        "descripcion" => array:1 [
          "es" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">N&#250;mero de ictus por intervalo de edad&#46;</p>"
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0065">Introducci&#243;n</span><p id="par0005" class="elsevierStylePara elsevierViewall">El ictus es la principal causa de discapacidad en adultos y la segunda causa de mortalidad global en Espa&#241;a &#8212;la primera en las mujeres&#8212;<a class="elsevierStyleCrossRef" href="#bib0160"><span class="elsevierStyleSup">1</span></a>&#46; Tiene un impacto sociosanitario considerable debido a su elevada prevalencia e incidencia y a la discapacidad y dependencia que produce&#44; y su repercusi&#243;n es a&#250;n mayor cuando afecta a personas j&#243;venes en situaci&#243;n laboral activa&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">Aunque cl&#225;sicamente se considera una enfermedad asociada a pacientes ancianos&#44; puede presentarse a cualquier edad&#46; IBERICTUS&#44; el mayor estudio epidemiol&#243;gico sobre ictus realizado en Espa&#241;a&#44; estim&#243; en 2006 un porcentaje de ictus en pacientes<span class="elsevierStyleHsp" style=""></span>&#8804;<span class="elsevierStyleHsp" style=""></span>55 a&#241;os del 9&#44;4&#37;<a class="elsevierStyleCrossRef" href="#bib0165"><span class="elsevierStyleSup">2</span></a>&#44; por lo que su incidencia es significativa&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">Los ictus en personas j&#243;venes &#40;especialmente los que ocurren por debajo de los 45 a&#241;os&#41; se relacionan tradicionalmente con condiciones infrecuentes como estados de hipercoagulabilidad&#44; enfermedades gen&#233;ticas o malformaciones vasculares&#46; Sin embargo&#44; en los &#250;ltimos a&#241;os se ha observado un aumento de su incidencia con relaci&#243;n a factores de riesgo vascular cl&#225;sicos como tabaquismo&#44; hipertensi&#243;n arterial&#44; dislipidemia&#44; obesidad&#44; diabetes<a class="elsevierStyleCrossRefs" href="#bib0170"><span class="elsevierStyleSup">3&#8211;9</span></a>&#44; y tambi&#233;n con el estr&#233;s psicosocial&#44; entidad de dif&#237;cil cuantificaci&#243;n que engloba elementos diferentes e interrelacionados como el estr&#233;s laboral&#44; problemas econ&#243;micos&#44; conflictos familiares o trastornos psicol&#243;gicos&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">En el presente estudio hemos analizado la incidencia y caracter&#237;sticas de los pacientes<span class="elsevierStyleHsp" style=""></span>&#8804;<span class="elsevierStyleHsp" style=""></span>55 a&#241;os que ingresan en una unidad de ictus de un hospital terciario&#44; tratando de determinar si la aparici&#243;n de ictus en sujetos j&#243;venes se relaciona con la presencia de factores de riesgo vascular cl&#225;sicos o de estr&#233;s psicosocial&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0070">Pacientes y m&#233;todos</span><p id="par0025" class="elsevierStylePara elsevierViewall">Nuestro hospital es un centro terciario de ictus perteneciente a la Red Ictus Madrid<a class="elsevierStyleCrossRef" href="#bib0205"><span class="elsevierStyleSup">10</span></a>&#46; Hemos realizado un estudio retrospectivo partiendo de un registro prospectivo de pacientes<span class="elsevierStyleHsp" style=""></span>&#8804;<span class="elsevierStyleHsp" style=""></span>55 a&#241;os con el diagn&#243;stico final de ictus que ingresaron en nuestra Unidad de Ictus durante el a&#241;o 2014&#46; Se excluyeron las hemorragias traum&#225;ticas&#44; subdurales y subaracnoideas&#46; Los pacientes fueron atendidos seg&#250;n las recomendaciones de las gu&#237;as de pr&#225;ctica cl&#237;nica de la Sociedad Espa&#241;ola de Neurolog&#237;a y del Plan de Atenci&#243;n al Ictus II&#46; 2010<a class="elsevierStyleCrossRefs" href="#bib0210"><span class="elsevierStyleSup">11&#8211;13</span></a>&#46; El estudio fue aprobado por nuestro Comit&#233; &#201;tico de Investigaci&#243;n Cl&#237;nica&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">Se recogieron las siguientes variables de acuerdo con un protocolo predefinido&#58; datos demogr&#225;ficos&#44; factores de riesgo vascular &#40;conocidos o descubiertos durante el ingreso&#44; como tabaquismo&#44; hipertensi&#243;n arterial&#44; diabetes mellitus&#44; dislipidemia&#44; obesidad&#44; fibrilaci&#243;n auricular y cardiopat&#237;as embol&#237;genas&#41;&#44; h&#225;bitos t&#243;xicos &#40;enolismo y consumo de drogas&#41;&#44; presencia de foramen oval permeable&#44; toma de anticonceptivos orales&#44; enfermedad oncol&#243;gica activa&#44; trastornos de la coagulaci&#243;n &#40;cong&#233;nitos o adquiridos&#41;&#44; migra&#241;a y estr&#233;s psicosocial&#46; El estr&#233;s psicosocial se defini&#243; como un estado de ansiedad&#44; tensi&#243;n&#44; irritabilidad o dificultad para conciliar el sue&#241;o relacionado con problemas externos&#44; especialmente familiares&#44; econ&#243;micos y laborales&#46; A los pacientes se les pregunt&#243; si se sent&#237;an o no estresados en la &#233;poca anterior al ictus y cumplimentaron la escala <span class="elsevierStyleItalic">Perceived Stress Scale &#40;</span>PSS&#41; para cuantificar el grado de estr&#233;s durante el mes previo<a class="elsevierStyleCrossRefs" href="#bib0225"><span class="elsevierStyleSup">14&#44;15</span></a>&#46; De las diferentes versiones validadas&#44; la original de 14 &#237;tems y 2 versiones breves de 10 y 4 &#237;tems&#44; se utiliz&#243; esta &#250;ltima &#40;PSS-4&#41; por su mayor aplicabilidad&#46; La escala&#44; que no utiliza puntos de corte&#44; punt&#250;a de 0 a 16 puntos&#58; el 0 es el m&#237;nimo y el 16 el m&#225;ximo grado de estr&#233;s &#40;<a class="elsevierStyleCrossRef" href="#tbl0005">tabla 1</a>&#41;&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><p id="par0035" class="elsevierStylePara elsevierViewall">Todos los pacientes fueron valorados de forma urgente por el neur&#243;logo de guardia &#40;con o sin activaci&#243;n del c&#243;digo ictus extrahospitalario&#41; y se les realiz&#243; una exploraci&#243;n general y neurol&#243;gica con la escala <span class="elsevierStyleItalic">National Institute of Health Stroke Scale</span>&#44; anal&#237;tica&#44; radiograf&#237;a de t&#243;rax&#44; electrocardiograma y tomograf&#237;a computarizada craneal&#46; Los pacientes que cumpl&#237;an criterios de tratamiento en fase aguda recibieron terapia de reperfusi&#243;n &#40;tromb&#243;lisis intravenosa&#44; tratamiento endovascular o ambos&#41;&#44; siguiendo las recomendaciones de las gu&#237;as cl&#237;nicas<a class="elsevierStyleCrossRefs" href="#bib0210"><span class="elsevierStyleSup">11&#44;16</span></a>&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">Durante el ingreso hospitalario se complet&#243; el estudio etiol&#243;gico con pruebas de imagen neurovascular &#40;angio-tomograf&#237;a computarizada o neurosonolog&#237;a&#41;&#44; resonancia magn&#233;tica craneal y test cardiol&#243;gicos &#40;ecocardiograma y holter-electrocardiograma de 24&#160;h&#41;&#46; En algunos casos se realizaron pruebas espec&#237;ficas para detectar enfermedades de la coagulaci&#243;n&#44; autoinmunes o infecciosas&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">Los tipos de ictus se clasificaron de acuerdo con los criterios de la Organizaci&#243;n Mundial de la Salud &#40;infarto cerebral&#44; ictus transitorio&#44; hemorragia intracraneal y trombosis venosa cerebral&#41;&#46; Se utiliz&#243; la clasificaci&#243;n <span class="elsevierStyleItalic">Trial of Org 10172 in Acute Stroke Treatment</span> &#40;TOAST&#41; para dividir los subtipos de ictus isqu&#233;mico en aterotromb&#243;tico&#44; cardioemb&#243;lico&#44; lacunar&#44; de etiolog&#237;a infrecuente y de etiolog&#237;a indeterminada<a class="elsevierStyleCrossRef" href="#bib0240"><span class="elsevierStyleSup">17</span></a>&#46; La evoluci&#243;n cl&#237;nica se determin&#243; con la escala de Rankin modificada &#40;eRm&#41;<a class="elsevierStyleCrossRef" href="#bib0245"><span class="elsevierStyleSup">18</span></a>&#44; y se consider&#243; una evoluci&#243;n favorable la independencia funcional a los 3 meses &#40;eRm 0-2&#41;&#46;</p><p id="par0050" class="elsevierStylePara elsevierViewall">Para el an&#225;lisis estad&#237;stico se utiliz&#243; el programa SPSS en su versi&#243;n 21&#46;0 para Windows&#46; Se utilizaron los test estad&#237;sticos Chi-cuadrado de Pearson y test exacto de Fisher para la comparaci&#243;n de variables categ&#243;ricas y la <span class="elsevierStyleItalic">t</span> de Student para la comparaci&#243;n de medias&#46; Se consider&#243; significativa una p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;05&#46; Se hizo un an&#225;lisis de subgrupos dividiendo a los pacientes en tramos de edad &#40;&#8804;45 y &#62;45 a&#241;os&#41; y por sexo&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0075">Resultados</span><p id="par0055" class="elsevierStylePara elsevierViewall">Durante el a&#241;o 2014&#44; 830 pacientes con un diagn&#243;stico final de ictus ingresaron en nuestra unidad&#46; De ellos&#44; 110 &#40;13&#44;3&#37;&#41; ten&#237;an &#8804;55 a&#241;os&#44; con predominio masculino &#40;60&#44;9&#37;&#41; y 35 pacientes &#40;4&#44;2&#37;&#41; ten&#237;an &#8804;45 a&#241;os&#44; con predominio en estos del sexo femenino &#40;19 vs&#46; 16&#41;&#46;</p><p id="par0060" class="elsevierStylePara elsevierViewall">El rango de edad estuvo entre 15 y 55 a&#241;os con una edad media de 46&#44;4<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>8&#44;1 a&#241;os y una mediana de 49 a&#241;os&#46; La edad media fue superior en los hombres &#40;47&#44;7 vs&#46; 44&#44;4 a&#241;os&#59; p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;05&#41;&#46; La incidencia global fue aumentando exponencialmente con relaci&#243;n a la edad &#40;<a class="elsevierStyleCrossRef" href="#fig0005">fig&#46; 1</a>&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0065" class="elsevierStylePara elsevierViewall">Un total de 92 pacientes &#40;83&#44;6&#37;&#41; tuvieron un ictus isqu&#233;mico&#58; 73 &#40;66&#44;4&#37;&#41; fueron infartos cerebrales y 19 &#40;17&#44;3&#37;&#41; ataques isqu&#233;micos transitorios&#46; Del total&#44; 14 pacientes &#40;12&#44;7&#37;&#41; presentaron una hemorragia intracraneal y 4 &#40;3&#44;6&#37;&#41; una trombosis de senos venosos cerebrales&#46;</p><p id="par0070" class="elsevierStylePara elsevierViewall">El 87&#44;6&#37; de los pacientes ten&#237;a al menos un factor de riesgo vascular cl&#225;sico y el 65&#37; 2 o m&#225;s factores de riesgo&#58; estos porcentajes fueron en el grupo de pacientes de &#8804;45 a&#241;os del 71&#44;4 y del 45&#44;7&#37;&#44; respectivamente&#46; De los factores cl&#225;sicos&#44; el tabaquismo fue el m&#225;s frecuente &#40;<a class="elsevierStyleCrossRef" href="#tbl0010">tabla 2</a>&#44; <a class="elsevierStyleCrossRef" href="#fig0010">fig&#46; 2</a>&#41;&#46; La mayor&#237;a de los factores de riesgo fueron m&#225;s frecuentes en el grupo de<span class="elsevierStyleHsp" style=""></span>&#62;45 a&#241;os&#44; aunque solo la hipertensi&#243;n &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;01&#41; y el consumo de alcohol &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;03&#41; alcanzaron significaci&#243;n estad&#237;stica&#46; En los varones&#44; la hipertensi&#243;n &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#44; el tabaquismo &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;008&#41; y la diabetes &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;02&#41; fueron m&#225;s frecuentes que en las mujeres y en estas hubo mayor prevalencia de migra&#241;a &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;02&#41;&#46; Muchos pacientes desconoc&#237;an sus factores de riesgo&#58; se descubrieron durante el ingreso un 64&#44;3&#37; de cardiopat&#237;as embol&#237;genas&#44; un 51&#44;1&#37; de dislipidemias&#44; un 25&#37; de diabetes y un 18&#44;2&#37; de hipertensiones arteriales&#46;</p><elsevierMultimedia ident="tbl0010"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0075" class="elsevierStylePara elsevierViewall">El 57&#44;2&#37; de los pacientes refer&#237;a estr&#233;s psicosocial en la etapa previa al ictus&#46; La puntuaci&#243;n media de la escala PSS fue de 5&#44;2&#44; cifra superior en los pacientes con estr&#233;s &#40;7&#44;3 vs&#46; 1&#44;9&#59; p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;05&#41; y en las mujeres &#40;6&#44;4 vs&#46; 4&#44;4&#59; p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;05&#41;&#46; Entre los diferentes tipos de ictus no existieron diferencias significativas en el porcentaje de pacientes con estr&#233;s ni en la puntuaci&#243;n de la escala PSS&#46;</p><p id="par0080" class="elsevierStylePara elsevierViewall">Las proporciones de cada subtipo de ictus se muestran en la <a class="elsevierStyleCrossRef" href="#tbl0015">tabla 3</a>&#46; Entre las causas infrecuentes de ictus isqu&#233;mico la m&#225;s prevalente fue la disecci&#243;n arterial &#40;7 pacientes&#44; 7&#44;6&#37; de los ictus isqu&#233;micos&#41;&#46; Otras causas infrecuentes fueron&#58; 3 ictus asociados a neoplasia por mecanismo procoagulante&#44; un s&#237;ndrome antifosfol&#237;pido&#44; un lupus eritematoso sist&#233;mico&#44; una vasculitis aislada del sistema nervioso central&#44; un ictus por embolia parad&#243;jica asociado al s&#237;ndrome de la clase turista<a class="elsevierStyleCrossRef" href="#bib0250"><span class="elsevierStyleSup">19</span></a> y un ictus hemodin&#225;mico en relaci&#243;n con un s&#237;ncope prolongado&#46;</p><elsevierMultimedia ident="tbl0015"></elsevierMultimedia><p id="par0085" class="elsevierStylePara elsevierViewall">Hubo 14 hemorragias intracraneales&#44; de las cuales 12 &#40;85&#44;7&#37;&#41; ocurrieron en varones y 11 &#40;78&#44;6&#37;&#41; fueron hipertensivas&#46; En los otros pacientes la etiolog&#237;a fue una sobredosificaci&#243;n de acenocumarol&#44; un cavernoma cerebral y un feocromocitoma&#46; Los 4 casos de trombosis venosa cerebral sucedieron en mujeres&#58; 3 fumaban y tomaban anticonceptivos orales y 2 ten&#237;an adem&#225;s una trombofilia primaria&#46; En otra paciente no se encontr&#243; ning&#250;n factor asociado&#46;</p><p id="par0090" class="elsevierStylePara elsevierViewall">La hospitalizaci&#243;n media fue de 8 d&#237;as &#40;rango 1-60&#41;&#46; El 82&#44;9&#37; de los pacientes tuvo un pron&#243;stico favorable a los 3 meses&#44; el 14&#44;3&#37; qued&#243; con secuelas graves &#40;eRm 3-5&#41; y 3 pacientes &#40;2&#44;8&#37;&#41; fallecieron&#46;</p><p id="par0095" class="elsevierStylePara elsevierViewall">Un total de 17 pacientes &#40;23&#44;3&#37; de los infartos cerebrales&#41; se beneficiaron de terapias de reperfusi&#243;n en fase aguda&#58; 10 &#40;13&#44;7&#37;&#41; recibieron fibrin&#243;lisis intravenosa&#44; 3 &#40;4&#44;1&#37;&#41; tratamiento endovascular y 4 &#40;5&#44;5&#37;&#41; ambos tratamientos&#46; La gravedad del ictus medida con la escala <span class="elsevierStyleItalic">National Institute of Health Stroke Scale</span> fue superior en los pacientes tratados respecto a los no tratados &#40;12&#44;4<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>7&#44;5 vs&#46; 4&#44;2<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>5&#44;3&#59; p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#44; la hospitalizaci&#243;n media fue similar &#40;8&#44;6 vs&#46; 7&#44;9 d&#237;as&#59; p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;76&#41; y la proporci&#243;n de pacientes con pron&#243;stico favorable fue menor en los pacientes que se trataron &#40;62&#44;5 vs&#46; 86&#44;5&#37;&#59; p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;03&#41;&#46; No hubo ning&#250;n caso de mortalidad ni de transformaci&#243;n hemorr&#225;gica entre los que recibieron terapia de reperfusi&#243;n&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0080">Discusi&#243;n</span><p id="par0100" class="elsevierStylePara elsevierViewall">Este estudio muestra el perfil del ictus en pacientes j&#243;venes que ingresan en una unidad especializada en Espa&#241;a&#46; El l&#237;mite de edad para considerar que un ictus ocurre en una persona joven es variable y la mayor&#237;a de los estudios fija un l&#237;mite entre 45 y 55 a&#241;os&#44; sin un criterio determinado<a class="elsevierStyleCrossRefs" href="#bib0170"><span class="elsevierStyleSup">3&#8211;8</span></a>&#46; En este trabajo optamos por los 55 a&#241;os para comparar la proporci&#243;n de ictus en j&#243;venes con los datos mostrados en el estudio IBERICTUS&#46;</p><p id="par0105" class="elsevierStylePara elsevierViewall">En cuanto a la edad media y la distribuci&#243;n por sexos no existieron diferencias con respecto a otros estudios con similares intervalos de edad<a class="elsevierStyleCrossRefs" href="#bib0185"><span class="elsevierStyleSup">6&#44;8</span></a>&#46; Tanto en hombres como en mujeres los factores de riesgo vascular fueron m&#225;s frecuentes que los observados en la poblaci&#243;n general<a class="elsevierStyleCrossRef" href="#bib0255"><span class="elsevierStyleSup">20</span></a>&#46; Los factores de riesgo fueron m&#225;s frecuentes en los hombres y en el grupo de &#62;45 a&#241;os&#44; lo que explicar&#237;a la preponderancia masculina y el incremento exponencial de ictus que se observa con la edad&#46; Es destacable que casi 3 de cada 4 pacientes del grupo de &#8804;45 a&#241;os presentaba alg&#250;n factor de riesgo vascular&#44; independientemente de la etiolog&#237;a del ictus&#46;</p><p id="par0110" class="elsevierStylePara elsevierViewall">En comparaci&#243;n con otros estudios&#44; la prevalencia de factores vasculares cl&#225;sicos fue globalmente superior&#44; con mayores tasas de tabaquismo&#44; hipertensi&#243;n&#44; obesidad y diabetes<a class="elsevierStyleCrossRefs" href="#bib0185"><span class="elsevierStyleSup">6&#44;8</span></a>&#46; Tambi&#233;n es destacable el elevado porcentaje de pacientes cuyos factores de riesgo se descubrieron durante el ingreso&#46; La elevada frecuencia de estos factores de riesgo&#44; inesperada en el grupo de &#8804;45 a&#241;os y en muchos casos desconocidos por los pacientes&#44; indica la necesidad de implementar estrategias intensivas de prevenci&#243;n en la poblaci&#243;n joven para evitar un primer evento vascular o una recurrencia&#46; Se ha demostrado que a mayor acumulaci&#243;n de factores de riesgo en adultos j&#243;venes&#44; mayor es el riesgo de recurrencia de eventos isqu&#233;micos<a class="elsevierStyleCrossRef" href="#bib0260"><span class="elsevierStyleSup">21</span></a>&#46;</p><p id="par0115" class="elsevierStylePara elsevierViewall">Una de las novedades que se introducen en el estudio fue el an&#225;lisis del papel del estr&#233;s psicosocial en los pacientes con ictus&#44; que afectaba a 6 de cada 10 pacientes&#46; Existe una evidencia moderada de que el estr&#233;s relacionado con el trabajo &#40;exigencias psicol&#243;gicas excesivas&#44; falta de apoyo social&#44; presi&#243;n&#44; etc&#46;&#41;&#44; los conflictos&#44; las crisis y el estr&#233;s en la vida familiar aumentan el riesgo de enfermedad cardiovascular<a class="elsevierStyleCrossRef" href="#bib0265"><span class="elsevierStyleSup">22</span></a>&#46; Recientemente diferentes estudios han observado una asociaci&#243;n entre el estr&#233;s y la enfermedad cerebrovascular&#44; que es independiente del resto de los factores de riesgo<a class="elsevierStyleCrossRefs" href="#bib0230"><span class="elsevierStyleSup">15&#44;23&#44;24</span></a>&#46; Es conocido que el estr&#233;s influye en una serie de mecanismos biol&#243;gicos y fomenta h&#225;bitos y estilos de vida poco saludables&#58; consumo de tabaco&#44; alimentaci&#243;n poco equilibrada&#44; sedentarismo o mala adherencia a tratamientos<a class="elsevierStyleCrossRef" href="#bib0265"><span class="elsevierStyleSup">22</span></a>&#46; Existe evidencia de que los programas de intervenci&#243;n psicol&#243;gica basados en el tratamiento del estr&#233;s como la terapia cognitivo-conductual pueden contribuir a mejorar el perfil de riesgo vascular y promover estilos de vida saludables<a class="elsevierStyleCrossRef" href="#bib0280"><span class="elsevierStyleSup">25</span></a>&#59; y consideramos que aquellos pacientes que han sufrido un ictus en edad laboral y asocian un alto grado de estr&#233;s psicosocial podr&#237;an beneficiarse de un tratamiento psicoterap&#233;utico dirigido al control del estr&#233;s como parte del programa de prevenci&#243;n secundaria del ictus&#46;</p><p id="par0120" class="elsevierStylePara elsevierViewall">Con relaci&#243;n a los tipos de ictus&#44; la proporci&#243;n de isqu&#233;micos y hemorr&#225;gicos fue similar a la descrita en la literatura<a class="elsevierStyleCrossRef" href="#bib0285"><span class="elsevierStyleSup">26</span></a>&#46; El ictus criptog&#233;nico es el m&#225;s frecuente en la mayor&#237;a de las series de ictus en sujetos j&#243;venes&#44; y representa entre un tercio y la mitad de los casos<a class="elsevierStyleCrossRef" href="#bib0195"><span class="elsevierStyleSup">8</span></a>&#46; Sin embargo&#44; la clasificaci&#243;n TOAST tiene unos criterios estrictos para poder clasificar algunos ictus como aterotromb&#243;ticos &#40;se requiere una estenosis mayor del 50&#37; de la arteria responsable&#41;&#44; lo que explica que muchos ictus se clasifiquen como criptog&#233;nicos&#44; aunque ocurran en pacientes con ateromatosis carot&#237;dea y presenten otros factores de riesgo vascular cuya relaci&#243;n con el ictus est&#225; bien documentada&#46; La proporci&#243;n de los subtipos de ictus isqu&#233;micos var&#237;a en cada estudio<a class="elsevierStyleCrossRef" href="#bib0290"><span class="elsevierStyleSup">27</span></a>&#46; En nuestra serie&#44; a los ictus criptog&#233;nicos les siguieron en frecuencia los infartos lacunares&#44; hallazgo observado &#250;nicamente en otro registro<a class="elsevierStyleCrossRef" href="#bib0295"><span class="elsevierStyleSup">28</span></a>&#59; esto se explica por la elevada prevalencia de hipertensi&#243;n arterial en ausencia de estenosis arteriales&#46; Los ictus de etiolog&#237;a cardioemb&#243;lica fueron relativamente infrecuentes&#44; aunque se sabe que tras algunos ictus criptog&#233;nicos puede subyacer una fibrilaci&#243;n auricular oculta<a class="elsevierStyleCrossRef" href="#bib0300"><span class="elsevierStyleSup">29</span></a>&#46; En el grupo de &#8804;45 a&#241;os&#44; a pesar de la elevada prevalencia de factores de riesgo&#44; solo un tercio de los ictus se atribuy&#243; a aterotrombosis&#44; cardioembolia o enfermedad de peque&#241;o vaso&#44; lo que indica que la presencia de factores de riesgo vascular podr&#237;a contribuir a la aparici&#243;n de ictus por otros mecanismos&#46;</p><p id="par0125" class="elsevierStylePara elsevierViewall">Debe resaltarse que la causa m&#225;s frecuente de las hemorragias intracraneales fue la hipertensiva &#40;78&#44;6&#37;&#41; y solo 3 casos se produjeron por otras causas&#46; En general&#44; la etiolog&#237;a de la hemorragia intracraneal es similar a la de los pacientes mayores&#44; con una mayor representaci&#243;n de malformaciones arteriovenosas y enfermedades de la coagulaci&#243;n en detrimento de aquellas relacionadas con la toma de anticoagulantes o la angiopat&#237;a amiloide<a class="elsevierStyleCrossRef" href="#bib0285"><span class="elsevierStyleSup">26</span></a>&#46;</p><p id="par0130" class="elsevierStylePara elsevierViewall">En cuanto a la evoluci&#243;n cl&#237;nica&#44; en el 82&#44;9&#37; de los pacientes fue favorable a los 3 meses&#44; dato similar a lo observado en otros estudios que muestran tasas de independencia funcional entre el 78 y el 94&#37;<a class="elsevierStyleCrossRef" href="#bib0305"><span class="elsevierStyleSup">30</span></a>&#46; Debe tenerse en cuenta que este porcentaje tambi&#233;n incluye los ataques isqu&#233;micos transitorios y los ictus menores&#44; de mejor pron&#243;stico general&#46; Considerando &#250;nicamente los ictus isqu&#233;micos tratados con terapias de reperfusi&#243;n &#40;en su mayor parte ictus graves&#41;&#44; cerca de 2&#47;3 de los pacientes fueron independientes a los 3 meses&#44; resultado que confirma que los sujetos j&#243;venes tienen generalmente mejor pron&#243;stico respecto a los pacientes de mayor edad<a class="elsevierStyleCrossRefs" href="#bib0190"><span class="elsevierStyleSup">7&#44;31</span></a>&#46;</p><p id="par0135" class="elsevierStylePara elsevierViewall">Las limitaciones principales de este trabajo son su car&#225;cter retrospectivo y la baja especificidad de la escala de estr&#233;s&#46;</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0085">Conclusiones</span><p id="par0140" class="elsevierStylePara elsevierViewall">En este estudio la proporci&#243;n de ictus en sujetos j&#243;venes fue un 30&#37; superior a la del estudio IBERICTUS&#44; lo que indica que la incidencia del ictus podr&#237;a estar aumentando en esta poblaci&#243;n&#46; Este aumento parece deberse a una elevada tasa de factores de riesgo vascular en un segmento de la poblaci&#243;n que desconoce su perfil de riesgo o no lo controla adecuadamente&#46; La mayor&#237;a de los factores de riesgo vascular son modificables&#44; y entre ellos se debe considerar el estr&#233;s psicosocial&#44; lo que hace necesario fomentar estrategias de prevenci&#243;n adecuadas para evitar eventos vasculares&#46; Por &#250;ltimo&#44; cabe resaltar que casi 2&#47;3 de los ictus isqu&#233;micos tratados con terapias de reperfusi&#243;n fueron funcionalmente independientes a los 3 meses&#44; lo que subraya la importancia de la detecci&#243;n temprana de los s&#237;ntomas de ictus tambi&#233;n en la poblaci&#243;n joven&#46;</p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0090">Financiaci&#243;n</span><p id="par0145" class="elsevierStylePara elsevierViewall">Este trabajo ha sido financiado con una beca de la Fundaci&#243;n Alberto Contador&#46;</p></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0095">Conflicto de intereses</span><p id="par0150" class="elsevierStylePara elsevierViewall">Los autores declaran no tener ning&#250;n conflicto de intereses&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:12 [
        0 => array:3 [
          "identificador" => "xres734836"
          "titulo" => "Resumen"
          "secciones" => array:4 [
            0 => array:2 [
              "identificador" => "abst0005"
              "titulo" => "Objetivos"
            ]
            1 => array:2 [
              "identificador" => "abst0010"
              "titulo" => "Pacientes y m&#233;todos"
            ]
            2 => array:2 [
              "identificador" => "abst0015"
              "titulo" => "Resultados"
            ]
            3 => array:2 [
              "identificador" => "abst0020"
              "titulo" => "Conclusiones"
            ]
          ]
        ]
        1 => array:2 [
          "identificador" => "xpalclavsec738648"
          "titulo" => "Palabras clave"
        ]
        2 => array:3 [
          "identificador" => "xres734835"
          "titulo" => "Abstract"
          "secciones" => array:4 [
            0 => array:2 [
              "identificador" => "abst0025"
              "titulo" => "Objectives"
            ]
            1 => array:2 [
              "identificador" => "abst0030"
              "titulo" => "Patients and methods"
            ]
            2 => array:2 [
              "identificador" => "abst0035"
              "titulo" => "Results"
            ]
            3 => array:2 [
              "identificador" => "abst0040"
              "titulo" => "Conclusions"
            ]
          ]
        ]
        3 => array:2 [
          "identificador" => "xpalclavsec738647"
          "titulo" => "Keywords"
        ]
        4 => array:2 [
          "identificador" => "sec0005"
          "titulo" => "Introducci&#243;n"
        ]
        5 => array:2 [
          "identificador" => "sec0010"
          "titulo" => "Pacientes y m&#233;todos"
        ]
        6 => array:2 [
          "identificador" => "sec0015"
          "titulo" => "Resultados"
        ]
        7 => array:2 [
          "identificador" => "sec0020"
          "titulo" => "Discusi&#243;n"
        ]
        8 => array:2 [
          "identificador" => "sec0025"
          "titulo" => "Conclusiones"
        ]
        9 => array:2 [
          "identificador" => "sec0030"
          "titulo" => "Financiaci&#243;n"
        ]
        10 => array:2 [
          "identificador" => "sec0035"
          "titulo" => "Conflicto de intereses"
        ]
        11 => array:1 [
          "titulo" => "Bibliograf&#237;a"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2016-03-05"
    "fechaAceptado" => "2016-05-06"
    "PalabrasClave" => array:2 [
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec738648"
          "palabras" => array:6 [
            0 => "Ictus"
            1 => "Ictus en adultos j&#243;venes"
            2 => "Infarto cerebral"
            3 => "Hemorragia cerebral"
            4 => "Factores de riesgo vascular"
            5 => "Estr&#233;s"
          ]
        ]
      ]
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec738647"
          "palabras" => array:6 [
            0 => "Stroke"
            1 => "Stroke in young adults"
            2 => "Cerebral infarction"
            3 => "Cerebral haemorrhage"
            4 => "Cardiovascular risk factors"
            5 => "Stress"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "es" => array:3 [
        "titulo" => "Resumen"
        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Objetivos</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Analizar la incidencia&#44; los factores de riesgo&#44; la etiolog&#237;a&#44; el tratamiento y la evoluci&#243;n cl&#237;nica de pacientes j&#243;venes con ictus&#46;</p></span> <span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Pacientes y m&#233;todos</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Registro retrospectivo de pacientes &#8804; 55 a&#241;os ingresados en una Unidad de Ictus durante el a&#241;o 2014&#46; Se recogi&#243; la incidencia sobre el total de ictus y se analizaron datos demogr&#225;ficos&#44; factores de riesgo&#44; grado de estr&#233;s&#44; tipo y etiolog&#237;a del ictus&#44; tratamientos de reperfusi&#243;n y evoluci&#243;n cl&#237;nica&#46;</p></span> <span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Resultados</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Se incluy&#243; a 110 pacientes&#44; la mayor&#237;a hombres &#40;60&#44;9&#37;&#44; ratio 1&#44;6&#58;1&#41;&#46; La incidencia fue del 13&#44;3&#37; &#40;110 de 830 ictus&#41;&#46; La mayor&#237;a de los pacientes ten&#237;a factores de riesgo vascular&#46; El tabaquismo fue el m&#225;s frecuente &#40;56&#44;4&#37;&#41;&#44; seguido de la hipertensi&#243;n arterial &#40;50&#37;&#41;&#44; dislipidemia &#40;42&#44;7&#37;&#41;&#44; obesidad &#40;33&#37;&#41;&#44; diabetes &#40;18&#44;2&#37;&#41; y cardiopat&#237;as embol&#237;genas &#40;12&#44;7&#37;&#41;&#46; El 64&#44;3&#37; de las cardiopat&#237;as y el 51&#44;1&#37; de las dislipidemias se descubrieron durante el ingreso&#46; El 57&#44;2&#37; de los pacientes presentaban estr&#233;s psicosocial en la etapa previa al ictus&#46; El 83&#44;6&#37; de los ictus fueron isqu&#233;micos&#44; el 12&#44;7&#37; hemorr&#225;gicos y el 3&#44;6&#37; trombosis de senos venosos&#46; De los ictus isqu&#233;micos&#44; el 30&#44;4&#37; fueron criptog&#233;nicos&#44; el 23&#44;9&#37; lacunares&#44; el 16&#44;3&#37; por causas infrecuentes&#44; el 15&#44;2&#37; aterotromb&#243;ticos y el 14&#44;1&#37; cardioemb&#243;licos&#46; El 78&#44;6&#37; de las hemorragias cerebrales fueron hipertensivas&#46; El 23&#44;3&#37; de los ictus isqu&#233;micos recibieron tratamientos de reperfusi&#243;n en fase aguda y se consiguieron niveles de independencia funcional a los 3 meses del 62&#44;5&#37;&#46;</p></span> <span id="abst0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Conclusiones</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">La mayor&#237;a de los ictus en pacientes &#8804; 55 a&#241;os parecen relacionarse con una elevada prevalencia de factores de riesgo vascular cl&#225;sicos y posiblemente de estr&#233;s psicosocial&#46;</p></span>"
        "secciones" => array:4 [
          0 => array:2 [
            "identificador" => "abst0005"
            "titulo" => "Objetivos"
          ]
          1 => array:2 [
            "identificador" => "abst0010"
            "titulo" => "Pacientes y m&#233;todos"
          ]
          2 => array:2 [
            "identificador" => "abst0015"
            "titulo" => "Resultados"
          ]
          3 => array:2 [
            "identificador" => "abst0020"
            "titulo" => "Conclusiones"
          ]
        ]
      ]
      "en" => array:3 [
        "titulo" => "Abstract"
        "resumen" => "<span id="abst0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Objectives</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">To analyse the incidence&#44; risk factors&#44; aetiology&#44; treatment and clinical evolution of young patients with stroke&#46;</p></span> <span id="abst0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Patients and methods</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Retrospective registry of patients aged 55 years or younger hospitalised in a stroke unit during 2014&#46; We recorded the incidence rate for all strokes and analysed demographic data&#44; risk factors&#44; degree of stress&#44; stroke type and aetiology&#44; reperfusion treatments and clinical evolution&#46;</p></span> <span id="abst0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Results</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">The study included 110 patients&#44; the majority of whom were men &#40;60&#46;9&#37;&#44; 1&#46;6&#58;1 ratio&#41;&#46; The incidence rate was 13&#46;3&#37; &#40;110 of 830 strokes&#41;&#46; Most of the patients had cardiovascular risk factors&#46; Smoking was the most common risk factor &#40;56&#46;4&#37;&#41;&#44; followed by arterial hypertension &#40;50&#37;&#41;&#44; dyslipidaemia &#40;42&#46;7&#37;&#41;&#44; obesity &#40;33&#37;&#41;&#44; diabetes &#40;18&#46;2&#37;&#41; and emboligenic heart disease &#40;12&#46;7&#37;&#41;&#46; Some 64&#46;3&#37; of the heart disease cases and 51&#46;1&#37; of the dyslipidaemia cases were discovered during hospitalisation&#46; Some 57&#46;2&#37; of the patients experienced psychosocial stress in the stage prior to the stroke&#46; Some 83&#46;6&#37; of the stroke cases were ischaemic&#44; 12&#46;7&#37; were haemorrhagic and 3&#46;6&#37; were venous sinus thrombosis&#46; Of the ischaemic stroke cases&#44; 30&#46;4&#37; were cryptogenic&#44; 23&#46;9&#37; were lacunar&#44; 16&#46;3&#37; were from uncommon causes&#44; 15&#46;2&#37; were atherothrombotic and 14&#46;1&#37; were cardioembolic&#46; Some 78&#46;6&#37; of the cerebral haemorrhage cases were hypertensive&#46; Some 23&#46;3&#37; of the ischaemic stroke cases underwent reperfusion treatments in the acute phase&#44; achieving levels of functional independence at 3 months of 62&#46;5&#37;&#46;</p></span> <span id="abst0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Conclusions</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">The majority of stroke events in patients 55 years of age or younger appear to be related to a high prevalence of classical cardiovascular risk factors and possibly to psychosocial stress&#46;</p></span>"
        "secciones" => array:4 [
          0 => array:2 [
            "identificador" => "abst0025"
            "titulo" => "Objectives"
          ]
          1 => array:2 [
            "identificador" => "abst0030"
            "titulo" => "Patients and methods"
          ]
          2 => array:2 [
            "identificador" => "abst0035"
            "titulo" => "Results"
          ]
          3 => array:2 [
            "identificador" => "abst0040"
            "titulo" => "Conclusions"
          ]
        ]
      ]
    ]
    "multimedia" => array:5 [
      0 => array:7 [
        "identificador" => "fig0005"
        "etiqueta" => "Figura 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 883
            "Ancho" => 1576
            "Tamanyo" => 74843
          ]
        ]
        "descripcion" => array:1 [
          "es" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">N&#250;mero de ictus por intervalo de edad&#46;</p>"
        ]
      ]
      1 => array:7 [
        "identificador" => "fig0010"
        "etiqueta" => "Figura 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 838
            "Ancho" => 1573
            "Tamanyo" => 77661
          ]
        ]
        "descripcion" => array:1 [
          "es" => "<p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">Factores de riesgo vascular cl&#225;sicos&#46;</p> <p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">HTA&#58; hipertensi&#243;n arterial&#46;</p>"
        ]
      ]
      2 => array:8 [
        "identificador" => "tbl0005"
        "etiqueta" => "Tabla 1"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at1"
            "detalle" => "Tabla "
            "rol" => "short"
          ]
        ]
        "tabla" => array:1 [
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">En el &#250;ltimo mes&#58;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Nunca&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Casi nunca&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">De vez en cuando&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">A menudo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Muy a menudo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">1&#46; &#191;Con qu&#233; frecuencia se ha sentido incapaz de controlar las cosas importantes en su vida&#63;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">2&#46; &#191;Con qu&#233; frecuencia ha confiado en su capacidad para manejar sus problemas personales&#63;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">3&#46; &#191;Con qu&#233; frecuencia ha sentido que las cosas le iban bien&#63;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">4&#46; &#191;Con qu&#233; frecuencia ha sentido que las dificultades se acumulaban y no pod&#237;a superarlas&#63;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab1212809.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "es" => "<p id="spar0060" class="elsevierStyleSimplePara elsevierViewall">Escala de estr&#233;s percibido&#44; versi&#243;n de 4 &#237;tems &#40;PSS-4&#41;</p>"
        ]
      ]
      3 => array:8 [
        "identificador" => "tbl0010"
        "etiqueta" => "Tabla 2"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at2"
            "detalle" => "Tabla "
            "rol" => "short"
          ]
        ]
        "tabla" => array:2 [
          "leyenda" => "<p id="spar0070" class="elsevierStyleSimplePara elsevierViewall">Datos expresados como n&#250;mero<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>desviaci&#243;n est&#225;ndar&#46;</p><p id="spar0075" class="elsevierStyleSimplePara elsevierViewall">FA&#58; fibrilaci&#243;n auricular&#59; IMC&#58; &#237;ndice de masa corporal&#59; M&#58; mujeres&#59; PSS-4&#58; Escala de estr&#233;s psicosocial&#59; V&#58; varones&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="" valign="top" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Total &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>110&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Varones &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>67&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Mujeres &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>43&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">p&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">&#8804;45 a&#241;os &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>35&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">&#62;45 a&#241;os &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>75&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">p&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Edad&#44; a&#241;os</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">46&#44;4<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>8&#44;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">47&#44;7<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>6&#44;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">44&#44;4<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>9&#44;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;04&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">36&#44;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>7&#44;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">50&#44;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>5&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">-&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Sexo&#44; n &#40;&#37;&#41;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">-&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">67 &#40;60&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">43 &#40;39&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">-&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">V 16 &#40;45&#44;7&#41;<br>M 19 &#40;54&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">V 51 &#40;68&#41;<br>M 24 &#40;32&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;04&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Altura&#44; cm</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">168&#44;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>9&#44;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">173&#44;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>7&#44;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">161&#44;4<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>7&#44;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#60;0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">167&#44;6<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>7&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">169&#44;6<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>10&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;35&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Peso&#44; kg</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">80&#44;7<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>21&#44;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">86<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>23&#44;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">72&#44;7<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>16&#44;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;002&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">77&#44;8<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>22&#44;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">82&#44;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>21&#44;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;36&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Tabaquismo&#44; n &#40;&#37;&#41;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">62 &#40;56&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">45 &#40;67&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">17 &#40;39&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;008&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">15 &#40;42&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">47 &#40;62&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;06&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Hipertensi&#243;n arterial&#44; n &#40;&#37;&#41;</span><br><span class="elsevierStyleHsp" style=""></span>Conocida<br><span class="elsevierStyleHsp" style=""></span>Desconocida&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">55 &#40;50&#41;<br>45 &#40;81&#44;8&#41;<br>10 &#40;18&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">44 &#40;65&#44;7&#41;<br>37 &#40;84&#44;1&#41;<br>7 &#40;15&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">11 &#40;25&#44;6&#41;<br>8 &#40;72&#44;7&#41;<br>3 &#40;27&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#60;0&#44;001<br><br>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">11 &#40;31&#44;4&#41;<br>9 &#40;81&#44;8&#41;<br>2 &#40;18&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">44 &#40;58&#44;7&#41;<br>36 &#40;81&#44;8&#41;<br>8 &#40;18&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;01<br><br>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Diabetes mellitus&#44; n &#40;&#37;&#41;</span><br><span class="elsevierStyleHsp" style=""></span>Conocida<br><span class="elsevierStyleHsp" style=""></span>Desconocida&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">20 &#40;18&#44;2&#41;<br>15 &#40;75&#41;<br>5 &#40;25&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">17 &#40;25&#44;4&#41;<br>12 &#40;70&#44;6&#41;<br>5 &#40;29&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">3 &#40;7&#41;<br>3 &#40;100&#41;<br>-&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;02<br><br>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">4 &#40;11&#44;4&#41;<br>2 &#40;50&#41;<br>2 &#40;50&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">16 &#40;21&#44;3&#41;<br>13 &#40;81&#44;3&#41;<br>3 &#40;18&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;29<br><br>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Dislipidemia&#44; n &#40;&#37;&#41;</span><br><span class="elsevierStyleHsp" style=""></span>Conocida<br><span class="elsevierStyleHsp" style=""></span>Desconocida&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">47 &#40;42&#44;7&#41;<br>23 &#40;48&#44;9&#41;<br>24 &#40;51&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">30 &#40;44&#44;8&#41;<br>14 &#40;47&#44;7&#41;<br>16 &#40;53&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">17 &#40;39&#44;5&#41;<br>9 &#40;52&#44;9&#41;<br>8 &#40;47&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;95<br><br>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">11 &#40;31&#44;4&#41;<br>6 &#40;54&#44;5&#41;<br>5 &#40;45&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">36 &#40;48&#41;<br>17 &#40;47&#44;2&#41;<br>19 &#40;52&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;15<br><br>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Obesidad &#40;IMC &#62;30&#41;&#44; n&#47;total &#40;&#37;&#41;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">33&#47;100 &#40;33&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">22&#47;60 &#40;36&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">11&#47;40 &#40;27&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;46&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">7&#47;32 &#40;21&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">26&#47;68 &#40;38&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;12&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Cardiopat&#237;as embol&#237;genas &#40;FA</span><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">&#43;</span><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">otras&#41;&#44; n &#40;&#37;&#41;</span><br><span class="elsevierStyleHsp" style=""></span>Conocida<br><span class="elsevierStyleHsp" style=""></span>Desconocida&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">14 &#40;12&#44;7&#41;<br><br>5 &#40;35&#44;7&#41;<br>9 &#40;64&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">8 &#40;11&#44;9&#41;<br><br>3 &#40;37&#44;5&#41;<br>5 &#40;62&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">6 &#40;13&#44;9&#41;<br><br>2 &#40;33&#44;3&#41;<br>4 &#40;66&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;99<br><br>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">3 &#40;8&#44;6&#41;<br><br>3 &#40;100&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">11 &#40;14&#44;7&#41;<br><br>4 &#40;36&#44;4&#41;<br>7 &#40;63&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;54<br><br>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Consumo de alcohol &#62;40</span><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">g&#47;d&#237;a&#44; n &#40;&#37;&#41;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">10 &#40;9&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">9 &#40;13&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1 &#40;1&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;08&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">-&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">10 &#40;13&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;03&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Foramen oval permeable&#44; n&#47;total &#40;&#37;&#41;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">6&#47;30 &#40;20&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">4&#47;14 &#40;28&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">2&#47;16 &#40;12&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;38&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">2&#47;10 &#40;20&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">4&#47;20 &#40;20&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&#44;00&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Anticonceptivos hormonales&#44; n &#40;&#37;&#41;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">7 &#40;6&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">-&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">7 &#40;16&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">-&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">7 &#40;20&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">-&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">&#60;0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Consumo de drogas&#44; n &#40;&#37;&#41;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">2 &#40;1&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">2 &#40;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">-&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">-&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1 &#40;2&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1 &#40;1&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;54&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Enfermedad oncol&#243;gica&#44; n &#40;&#37;&#41;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">4 &#40;3&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1 &#40;1&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">3 &#40;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;30&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">-&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">4 &#40;5&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;30&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Enfermedades de la coagulaci&#243;n&#44; n &#40;&#37;&#41;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">6 &#40;5&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">3 &#40;4&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">3 &#40;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;68&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">2 &#40;5&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">4 &#40;5&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&#44;00&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Migra&#241;a&#44; n &#40;&#37;&#41;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">11 &#40;10&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">3 &#40;4&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">8 &#40;18&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;02&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">6 &#40;17&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">5 &#40;6&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;10&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Estr&#233;s psicosocial&#44; n&#47;total &#40;&#37;&#41;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">55&#47;96 &#40;57&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">32&#47;57 &#40;56&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">23&#47;39 &#40;59&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;70&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">16&#47;29 &#40;55&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">39&#47;67 &#40;58&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;82&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Escala PSS-4 &#40;n</span><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">&#61;</span><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">85&#41;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">5&#44;2<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">4&#44;4<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">6&#44;4<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>5&#44;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;04&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">6&#44;25<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">4&#44;8<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#44;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;19&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Escala PSS-4 pacientes estresados &#40;n</span><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">&#61;</span><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">52&#41;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">7&#44;3<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">6&#44;2<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#44;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">8&#44;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#44;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;03&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">8&#44;7<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#44;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">6&#44;8<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>4&#44;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;18&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Escala PSS-4 pacientes no estresados &#40;n</span><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">&#61;</span><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">33&#41;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&#44;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1&#44;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&#44;65<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1&#44;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">2&#44;2<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;28&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">2&#44;2<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1&#44;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">1&#44;7<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1&#44;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">0&#44;43&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab1212808.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "es" => "<p id="spar0065" class="elsevierStyleSimplePara elsevierViewall">Datos demogr&#225;ficos y factores de riesgo</p>"
        ]
      ]
      4 => array:8 [
        "identificador" => "tbl0015"
        "etiqueta" => "Tabla 3"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at3"
            "detalle" => "Tabla "
            "rol" => "short"
          ]
        ]
        "tabla" => array:1 [
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="" valign="top" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Total&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Varones&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Mujeres&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">p&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">&#8804; 45 a&#241;os&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">&#62; 45 a&#241;os&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">p&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Ictus isqu&#233;mico&#44; n</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top"><span class="elsevierStyleItalic">92</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">55&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">37&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">-&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">24&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">68&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">-&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Aterotromb&#243;tico&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">14 &#40;15&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11 &#40;20&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3 &#40;8&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;15&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">-&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">14 &#40;20&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;02&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Cardioemb&#243;lico&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">13 &#40;14&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7 &#40;12&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6 &#40;16&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;87&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3 &#40;12&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10 &#40;14&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&#44;00&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Lacunar&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">22 &#40;23&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">15 &#40;27&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7 &#40;18&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;50&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5 &#40;20&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">17 &#40;25&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;79&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Etiolog&#237;a infrecuente&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">15 &#40;16&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6 &#40;10&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9 &#40;24&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;16&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6 &#40;25&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9 &#40;13&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;21&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Etiolog&#237;a Indeterminada&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">28 &#40;30&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">16 &#40;29&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">12 &#40;32&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;91&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10 &#40;41&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">18 &#40;26&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;20&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="8" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Hemorragia cerebral&#44; n</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">14&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">12&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">-&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">-&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Hipertensiva&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">11 &#40;78&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">10 &#40;83&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;50&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;40&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">5 &#40;71&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6 &#40;85&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&#44;00&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Relacionada con anticoagulaci&#243;n&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;7&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;8&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">-&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&#44;00&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">-&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;14&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&#44;00&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Malformaci&#243;n vascular&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;7&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">-&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;50&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#44;14&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;14&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">-&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&#44;00&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Otras etiolog&#237;as&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;7&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;8&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">-&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&#44;00&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;14&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">-&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&#44;00&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="8" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Trombosis de senos venosos&#44; n</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">-&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">-&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">-&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">-&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Tabaquismo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3 &#40;75&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">-&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3 &#40;75&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&#44;00&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3 &#40;75&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">-&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&#44;00&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Enfermedades coagulaci&#243;n&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;50&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">-&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;50&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&#44;00&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2 &#40;50&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">-&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&#44;00&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Anticonceptivos hormonales&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3 &#40;75&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">-&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3 &#40;75&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&#44;00&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3 &#40;75&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">-&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&#44;00&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Ning&#250;n factor de riesgo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;25&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">-&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;25&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&#44;00&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1 &#40;25&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">-&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&#44;00&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab1212807.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "es" => "<p id="spar0080" class="elsevierStyleSimplePara elsevierViewall">Tipos de ictus y etiolog&#237;a</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "Bibliograf&#237;a"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:31 [
            0 => array:3 [
              "identificador" => "bib0160"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Instituto Nacional de Estad&#237;stica Defunciones seg&#250;n la causa de muerte&#46; 2013 &#91;consultado 15 Feb 2016&#93;&#46; Disponible en&#58; <a id="intr0005" class="elsevierStyleInterRef" href="http://www.ine.es/prensa/np896.pdf">http&#58;&#47;&#47;www&#46;ine&#46;es&#47;prensa&#47;np896&#46;pdf</a>"
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0165"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Stroke and transient ischemic attack incidence rate in Spain&#58; The IBERICTUS study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "J&#46; D&#237;az-Guzm&#225;n"
                            1 => "J&#46;A&#46; Egido"
                            2 => "R&#46; Gabriel-S&#225;nchez"
                            3 => "G&#46; Barber&#225;-Comes"
                            4 => "B&#46; Fuentes-Gimeno"
                            5 => "C&#46; Fern&#225;ndez-P&#233;rez"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1159/000342652"
                      "Revista" => array:6 [
                        "tituloSerie" => "Cerebrovasc Dis&#46;"
                        "fecha" => "2012"
                        "volumen" => "34"
                        "paginaInicial" => "272"
                        "paginaFinal" => "281"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23095851"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0170"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Analysis of 1008 consecutive patients aged 15&#8211;49 with first-ever ischemic stroke&#58; The Helsinki young stroke registry"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "J&#46; Putaala"
                            1 => "A&#46;J&#46; Metso"
                            2 => "T&#46;M&#46; Metso"
                            3 => "N&#46; Konkola"
                            4 => "Y&#46; Kraemer"
                            5 => "E&#46; Haapaniemi"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1161/STROKEAHA.108.529883"
                      "Revista" => array:6 [
                        "tituloSerie" => "Stroke&#46;"
                        "fecha" => "2009"
                        "volumen" => "40"
                        "paginaInicial" => "1195"
                        "paginaFinal" => "1203"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19246709"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0175"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Long-term prognosis of ischemic stroke in young adults&#46; Study of 272 cases"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "J&#46;F&#46; Varona"
                            1 => "F&#46; Bermejo"
                            2 => "J&#46;M&#46; Guerra"
                            3 => "J&#46;A&#46; Molina"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s00415-004-0583-0"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Neurol&#46;"
                        "fecha" => "2004"
                        "volumen" => "251"
                        "paginaInicial" => "1507"
                        "paginaFinal" => "1514"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15645352"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0180"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Etiology of first-ever ischaemic stroke in European young adults&#58; The 15 cities young stroke study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "N&#46; Yesilot Barlas"
                            1 => "J&#46; Putaala"
                            2 => "U&#46; Waje-Andreassen"
                            3 => "S&#46; Vassilopoulou"
                            4 => "K&#46; Nardi"
                            5 => "C&#46; Odier"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/ene.12228"
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur J Neurol&#46;"
                        "fecha" => "2013"
                        "volumen" => "20"
                        "paginaInicial" => "1431"
                        "paginaFinal" => "1439"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23837733"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0185"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Lifestyle risk factors for ischemic stroke and transient ischemic attack in young adults in the stroke in young Fabry patients study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "B&#46; Von Sarnowski"
                            1 => "J&#46; Putaala"
                            2 => "U&#46; Grittner"
                            3 => "B&#46; Gaertner"
                            4 => "U&#46; Schminke"
                            5 => "S&#46; Curtze"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1161/STROKEAHA.112.665190"
                      "Revista" => array:6 [
                        "tituloSerie" => "Stroke&#46;"
                        "fecha" => "2013"
                        "volumen" => "44"
                        "paginaInicial" => "119"
                        "paginaFinal" => "125"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23150649"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0190"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Ischemic stroke and transient ischemic attack in young adults&#58; Risk factors&#44; diagnostic yield&#44; neuroimaging&#44; and thrombolysis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "R&#46; Ji"
                            1 => "L&#46;H&#46; Schwamm"
                            2 => "M&#46;A&#46; Pervez"
                            3 => "A&#46;B&#46; Singhal"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1001/jamaneurol.2013.575"
                      "Revista" => array:6 [
                        "tituloSerie" => "JAMA Neurol&#46;"
                        "fecha" => "2013"
                        "volumen" => "70"
                        "paginaInicial" => "51"
                        "paginaFinal" => "57"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23108720"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0195"
              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Risk factors&#44; aetiology and outcome of ischaemic stroke in young adults&#58; The Swiss Young Stroke Study &#40;SYSS&#41;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "B&#46; Goeggel Simonetti"
                            1 => "M&#46;L&#46; Mono"
                            2 => "U&#46; Huynh-Do"
                            3 => "P&#46; Michel"
                            4 => "C&#46; Odier"
                            5 => "R&#46; Sztajzel"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s00415-015-7805-5"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Neurol&#46;"
                        "fecha" => "2015"
                        "volumen" => "262"
                        "paginaInicial" => "2025"
                        "paginaFinal" => "2032"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26067218"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib0200"
              "etiqueta" => "9"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Ischaemic stroke in young adults&#58; Risk factors and long-term consequences"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "N&#46;A&#46; Maaijwee"
                            1 => "L&#46;C&#46; Rutten-Jacobs"
                            2 => "P&#46; Schaapsmeerders"
                            3 => "E&#46;J&#46; van Dijk"
                            4 => "F&#46;E&#46; de Leeuw"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1038/nrneurol.2014.72"
                      "Revista" => array:7 [
                        "tituloSerie" => "Nat Rev Neurol&#46;"
                        "fecha" => "2014"
                        "volumen" => "10"
                        "paginaInicial" => "315"
                        "paginaFinal" => "325"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24776923"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0735109710003402"
                          "estado" => "S300"
                          "issn" => "07351097"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib0205"
              "etiqueta" => "10"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Foro de Ictus de la Asociaci&#243;n Madrile&#241;a de Neurolog&#237;a en colaboraci&#243;n con el Servicio Madrile&#241;o de Salud&#58; Atenci&#243;n a los Pacientes con Ictus de la Comunidad Aut&#243;noma de Madrid 2014 &#91;consultado 15 Feb 2016&#93;&#46; Disponible en&#58; <a id="intr0010" class="elsevierStyleInterRef" href="http://www.madrid.org/cs/Satellite?blobcol=urldata%26blobheader=application%2Fpdf%26blobheadername1=Content-Disposition%26blobheadervalue1=filename%3DPLAN+ICTUS_250614.pdf%26blobkey=id%26blobtable=MungoBlobs%26blobwhere=1352883653174%26ssbinary=true">http&#58;&#47;&#47;www&#46;madrid&#46;org&#47;cs&#47;Satellite&#63;blobcol&#61;urldata&#38;blobheader&#61;application&#37;2Fpdf&#38;blobheadername1&#61;Content-Disposition&#38;blobheadervalue1&#61;filename&#37;3DPLAN&#43;ICTUS&#95;250614&#46;pdf&#38;blobkey&#61;id&#38;blobtable&#61;MungoBlobs&#38;blobwhere&#61;1352883653174&#38;ssbinary&#61;true</a>"
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib0210"
              "etiqueta" => "11"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Gu&#237;a para el tratamiento del infarto cerebral agudo"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M&#46; Alonso de Leci&#241;ana"
                            1 => "J&#46;A&#46; Egido"
                            2 => "I&#46; Casado"
                            3 => "M&#46; Rib&#243;"
                            4 => "A&#46; D&#225;valos"
                            5 => "J&#46; Masjuan"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.nrl.2011.09.012"
                      "Revista" => array:6 [
                        "tituloSerie" => "Neurolog&#237;a&#46;"
                        "fecha" => "2014"
                        "volumen" => "29"
                        "paginaInicial" => "102"
                        "paginaFinal" => "122"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22152803"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib0215"
              "etiqueta" => "12"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Gu&#237;as de actuaci&#243;n cl&#237;nica en la hemorragia intracerebral"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M&#46; Rodr&#237;guez-Y&#225;&#241;ez"
                            1 => "M&#46; Castellanos"
                            2 => "M&#46;M&#46; Freijo"
                            3 => "J&#46;C&#46; L&#243;pez Fern&#225;ndez"
                            4 => "J&#46; Mart&#237;-F&#224;bregas"
                            5 => "F&#46; Nombela"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.nrl.2011.03.010"
                      "Revista" => array:6 [
                        "tituloSerie" => "Neurolog&#237;a&#46;"
                        "fecha" => "2013"
                        "volumen" => "28"
                        "paginaInicial" => "236"
                        "paginaFinal" => "249"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21570742"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib0220"
              "etiqueta" => "13"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Stroke health care plan &#40;ICTUS II&#46; 2010&#41;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "J&#46; Masjuan"
                            1 => "J&#46; Alvarez-Sab&#237;n"
                            2 => "J&#46; Arenillas"
                            3 => "S&#46; Calleja"
                            4 => "J&#46; Castillo"
                            5 => "A&#46; D&#225;valos"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.nrl.2010.05.008"
                      "Revista" => array:6 [
                        "tituloSerie" => "Neurolog&#237;a&#46;"
                        "fecha" => "2011"
                        "volumen" => "26"
                        "paginaInicial" => "383"
                        "paginaFinal" => "396"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21163236"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib0225"
              "etiqueta" => "14"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A global measure of perceived stress"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "S&#46; Cohen"
                            1 => "T&#46; Kamarck"
                            2 => "R&#46; Mermelstein"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Health Soc Behav&#46;"
                        "fecha" => "1983"
                        "volumen" => "24"
                        "paginaInicial" => "385"
                        "paginaFinal" => "396"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6668417"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib0230"
              "etiqueta" => "15"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Psychosocial distress and stroke risk in older adults"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "K&#46;M&#46; Henderson"
                            1 => "C&#46;J&#46; Clark"
                            2 => "T&#46;T&#46; Lewis"
                            3 => "N&#46;T&#46; Aggarwal"
                            4 => "T&#46; Beck"
                            5 => "H&#46; Guo"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1161/STROKEAHA.112.679159"
                      "Revista" => array:6 [
                        "tituloSerie" => "Stroke&#46;"
                        "fecha" => "2013"
                        "volumen" => "44"
                        "paginaInicial" => "367"
                        "paginaFinal" => "372"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23238864"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib0235"
              "etiqueta" => "16"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "2015 American Heart Association&#47;American Stroke Association focused update of the 2013 guidelines for the early management of patients with acute ischemic stroke regarding endovascular treatment&#58; A guideline for healthcare professionals from the American Heart Association&#47;American Stroke Association"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "W&#46;J&#46; Powers"
                            1 => "C&#46;P&#46; Derdeyn"
                            2 => "J&#46; Biller"
                            3 => "C&#46;S&#46; Coffey"
                            4 => "B&#46;L&#46; Hoh"
                            5 => "E&#46;C&#46; Jauch"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1161/STR.0000000000000074"
                      "Revista" => array:6 [
                        "tituloSerie" => "Stroke&#46;"
                        "fecha" => "2015"
                        "volumen" => "46"
                        "paginaInicial" => "3020"
                        "paginaFinal" => "3035"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26123479"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib0240"
              "etiqueta" => "17"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Classification of subtype of acute ischemic stroke&#46; Definitions for use in a multicenter clinical trial&#46; TOAST&#46; Trial of Org 10172 in acute stroke treatment"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "H&#46;P&#46; Adams Jr&#46;"
                            1 => "B&#46;H&#46; Bendixen"
                            2 => "L&#46;J&#46; Kappelle"
                            3 => "J&#46; Biller"
                            4 => "B&#46;B&#46; Love"
                            5 => "D&#46;L&#46; Gordon"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Stroke&#46;"
                        "fecha" => "1993"
                        "volumen" => "24"
                        "paginaInicial" => "35"
                        "paginaFinal" => "41"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7678184"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib0245"
              "etiqueta" => "18"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Interobserver agreement for the assessment of handicap in stroke patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "J&#46;C&#46; Van Swieten"
                            1 => "P&#46;J&#46; Koudstaal"
                            2 => "M&#46;C&#46; Visser"
                            3 => "H&#46;J&#46; Schouten"
                            4 => "J&#46; van Gijn"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Stroke&#46;"
                        "fecha" => "1988"
                        "volumen" => "19"
                        "paginaInicial" => "604"
                        "paginaFinal" => "607"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3363593"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib0250"
              "etiqueta" => "19"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Stroke in commercial flights"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "R&#46; &#193;lvarez-Velasco"
                            1 => "J&#46; Masjuan"
                            2 => "A&#46; DeFelipe"
                            3 => "I&#46; Corral"
                            4 => "C&#46; Est&#233;vez-Fraga"
                            5 => "L&#46; Crespo"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1161/STROKEAHA.115.012637"
                      "Revista" => array:7 [
                        "tituloSerie" => "Stroke&#46;"
                        "fecha" => "2016"
                        "volumen" => "47"
                        "paginaInicial" => "1117"
                        "paginaFinal" => "1119"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26892280"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0735109707015604"
                          "estado" => "S300"
                          "issn" => "07351097"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib0255"
              "etiqueta" => "20"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prevalence of cardiovascular risk factors in the Spanish working population"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M&#46;A&#46; S&#225;nchez-Chaparro"
                            1 => "J&#46; Rom&#225;n-Garc&#237;a"
                            2 => "E&#46; Calvo-Bonacho"
                            3 => "T&#46; G&#243;mez-Larios"
                            4 => "A&#46; Fern&#225;ndez-Meseguer"
                            5 => "J&#46;C&#46; Sainz-Guti&#233;rrez"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Rev Esp Cardiol&#46;"
                        "fecha" => "2006"
                        "volumen" => "59"
                        "paginaInicial" => "421"
                        "paginaFinal" => "430"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16750139"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            20 => array:3 [
              "identificador" => "bib0260"
              "etiqueta" => "21"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "How does number of risk factors affect prognosis in young patients with ischemic stroke&#63;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "J&#46; Putaala"
                            1 => "E&#46; Haapaniemi"
                            2 => "M&#46; Kaste"
                            3 => "T&#46; Tatlisumak"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1161/STROKEAHA.111.635276"
                      "Revista" => array:6 [
                        "tituloSerie" => "Stroke"
                        "fecha" => "2012"
                        "volumen" => "43"
                        "paginaInicial" => "356"
                        "paginaFinal" => "361"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22052508"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            21 => array:3 [
              "identificador" => "bib0265"
              "etiqueta" => "22"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:1 [
                      "titulo" => "Gu&#237;a europea sobre prevenci&#243;n de la enfermedad cardiovascular en la pr&#225;ctica cl&#237;nica &#40;versi&#243;n 2012&#41;"
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "Rev Esp Cardiol&#46;"
                        "fecha" => "2012"
                        "volumen" => "65"
                        "itemHostRev" => array:3 [
                          "pii" => "S0735109701014450"
                          "estado" => "S300"
                          "issn" => "07351097"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            22 => array:3 [
              "identificador" => "bib0270"
              "etiqueta" => "23"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Perceived stress is associated with subclinical cerebrovascular disease in older adults"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "N&#46;T&#46; Aggarwal"
                            1 => "C&#46;J&#46; Clark"
                            2 => "T&#46;L&#46; Beck"
                            3 => "C&#46;F&#46; Mendes de Leon"
                            4 => "C&#46; DeCarli"
                            5 => "D&#46;A&#46; Evans"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.jagp.2012.06.001"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Geriatr Psychiatry&#46;"
                        "fecha" => "2014"
                        "volumen" => "22"
                        "paginaInicial" => "53"
                        "paginaFinal" => "62"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23567443"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            23 => array:3 [
              "identificador" => "bib0275"
              "etiqueta" => "24"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Chronic stress&#44; depressive symptoms&#44; anger&#44; hostility&#44; and risk of stroke and transient ischemic attack in the multi-ethnic study of atherosclerosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "S&#46;A&#46; Everson-Rose"
                            1 => "N&#46;S&#46; Roetker"
                            2 => "P&#46;L&#46; Lutsey"
                            3 => "K&#46;N&#46; Kershaw"
                            4 => "W&#46;T&#46; Longstreth Jr&#46;"
                            5 => "R&#46;L&#46; Sacco"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1161/STROKEAHA.114.004815"
                      "Revista" => array:7 [
                        "tituloSerie" => "Stroke&#46;"
                        "fecha" => "2014"
                        "volumen" => "45"
                        "paginaInicial" => "2318"
                        "paginaFinal" => "2323"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25013018"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S014067360209894X"
                          "estado" => "S300"
                          "issn" => "01406736"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            24 => array:3 [
              "identificador" => "bib0280"
              "etiqueta" => "25"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Randomized controlled trial of cognitive behavioral therapy vs&#46; standard treatment to prevent recurrent cardiovascular events in patients with coronary heart disease&#58; Secondary Prevention in Uppsala Primary Health Care project &#40;SUPRIM&#41;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "M&#46; Gulliksson"
                            1 => "G&#46; Burell"
                            2 => "B&#46; Vessby"
                            3 => "L&#46; Lundin"
                            4 => "H&#46; Toss"
                            5 => "K&#46; Sv&#228;rdsudd"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1001/archinternmed.2010.510"
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Intern Med&#46;"
                        "fecha" => "2011"
                        "volumen" => "171"
                        "paginaInicial" => "134"
                        "paginaFinal" => "140"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21263103"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            25 => array:3 [
              "identificador" => "bib0285"
              "etiqueta" => "26"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Classification of the cerebrovascular diseases&#46; Iberoamerican Cerebrovascular Diseases Society"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "E&#46; D&#237;ez-Tejedor"
                            1 => "O&#46; del Brutto"
                            2 => "J&#46; Alvarez Sab&#237;n"
                            3 => "M&#46; Mu&#241;oz"
                            4 => "G&#46; Abiusi"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Rev Neurol&#46;"
                        "fecha" => "2001"
                        "volumen" => "33"
                        "paginaInicial" => "455"
                        "paginaFinal" => "464"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11727215"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0735109709007025"
                          "estado" => "S300"
                          "issn" => "07351097"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            26 => array:3 [
              "identificador" => "bib0290"
              "etiqueta" => "27"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Strokes in young adults&#58; Epidemiology and prevention"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "D&#46; Smajlovi&#263;"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.2147/VHRM.S53203"
                      "Revista" => array:7 [
                        "tituloSerie" => "Vasc Health Risk Manag&#46;"
                        "fecha" => "2015"
                        "volumen" => "11"
                        "paginaInicial" => "157"
                        "paginaFinal" => "164"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25750539"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0140673606689678"
                          "estado" => "S300"
                          "issn" => "01406736"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            27 => array:3 [
              "identificador" => "bib0295"
              "etiqueta" => "28"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Characteristics of stroke in young adults in Tuzla Canton&#44; Bosnia and Herzegovina"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "D&#381; Smajlovic&#236;"
                            1 => "D&#46; Salihovic&#236;"
                            2 => "Ibrahimagic&#236; O&#46; C&#236;"
                            3 => "O&#46; Sinanovic&#236;"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Coll Antropol&#46;"
                        "fecha" => "2013"
                        "volumen" => "37"
                        "paginaInicial" => "515"
                        "paginaFinal" => "519"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23940998"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            28 => array:3 [
              "identificador" => "bib0300"
              "etiqueta" => "29"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Subclinical auricular fibrillation and the risk of stroke"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "J&#46;S&#46; Healey"
                            1 => "S&#46;J&#46; Connolly"
                            2 => "M&#46;R&#46; Gold"
                            3 => "C&#46;W&#46; Israel"
                            4 => "I&#46;C&#46; van Gelder"
                            5 => "A&#46; Capucci"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1056/NEJMoa1105575"
                      "Revista" => array:6 [
                        "tituloSerie" => "N Engl J Med&#46;"
                        "fecha" => "2012"
                        "volumen" => "366"
                        "paginaInicial" => "120"
                        "paginaFinal" => "129"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22236222"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            29 => array:3 [
              "identificador" => "bib0305"
              "etiqueta" => "30"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Recognition and management of stroke in young adults and adolescents"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "A&#46;B&#46; Singhal"
                            1 => "J&#46; Biller"
                            2 => "M&#46;S&#46; Elkind"
                            3 => "H&#46;J&#46; Fullerton"
                            4 => "E&#46;C&#46; Jauch"
                            5 => "S&#46;J&#46; Kittner"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1212/WNL.0b013e3182a4a451"
                      "Revista" => array:6 [
                        "tituloSerie" => "Neurology&#46;"
                        "fecha" => "2013"
                        "volumen" => "81"
                        "paginaInicial" => "1089"
                        "paginaFinal" => "1097"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23946297"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            30 => array:3 [
              "identificador" => "bib0310"
              "etiqueta" => "31"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Intravenous thrombolysis in young stroke patients&#58; Results from the SITS-ISTR"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "D&#46; Toni"
                            1 => "N&#46; Ahmed"
                            2 => "A&#46; Anzini"
                            3 => "S&#46; Lorenzano"
                            4 => "M&#46; Brozman"
                            5 => "M&#46; Kaste"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1212/WNL.0b013e31824d966b"
                      "Revista" => array:6 [
                        "tituloSerie" => "Neurology&#46;"
                        "fecha" => "2012"
                        "volumen" => "78"
                        "paginaInicial" => "880"
                        "paginaFinal" => "887"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22402853"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "es"
  "url" => "/00142565/0000021600000007/v1_201609280158/S0014256516300819/v1_201609280158/es/main.assets"
  "Apartado" => array:4 [
    "identificador" => "1062"
    "tipo" => "SECCION"
    "es" => array:2 [
      "titulo" => "Originales"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "es"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/00142565/0000021600000007/v1_201609280158/S0014256516300819/v1_201609280158/es/main.pdf?idApp=WRCEE&text.app=https://revclinesp.es/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0014256516300819?idApp=WRCEE"
]
Compartir
Número actual
Información de la revista
Artículo anterior | Artículo siguiente
Read this article in English
Exportar referencia
Compartir
Compartir
Imprimir
Descargar PDF
Más opciones de artículo
Estadísticas
Apartados
  • Resumen
  • Palabras clave
  • Abstract
  • Keywords
ORIGINAL
DOI: 10.1016/j.rce.2016.05.008
Ictus en adultos jóvenes: incidencia, factores de riesgo, tratamiento y pronóstico
Stroke in young adults: Incidence rate, risk factors, treatment and prognosis
Descargar PDF
F.J. González-Gómez
Autor para correspondencia
javiergonzalezneurologia@gmail.com

Autor para correspondencia.
, P. Pérez-Torre, A. DeFelipe, R. Vera, C. Matute, A. Cruz-Culebras, R. Álvarez-Velasco, J. Masjuan
Unidad de Ictus, Servicio de Neurología, Hospital Universitario Ramón y Cajal, Instituto de Investigación IRYCIS, Universidad de Alcalá de Henares, Madrid, España
Contenido relacionado
De los factores psicológicos que influyen en otras afecciones médicas a los procesos psicosomáticos: ¿una lección olvidada?
Rev Clin Esp. 2016;216:367-910.1016/j.rce.2016.06.005
R. Campos Ródenas

Comprar documento

Para la compra de este documento es necesario que rellene el siguiente formulario:

Afganistan
Albania
Alemania
Andorra
Angola
Anguilla
Antartica
Antigua and barbuda
Antillas holandesas
Arabia saudita
Argelia
Argentina
Armenia
Aruba
Australia
Austria
Azerbaijan
Bahamas
Bahrain
Bangladesh
Barbados
Belarus
Belgica
Belice
Benin
Bermudas/antillas britanicas
Bhutan
Bolivia
Bosnia y herzegowina
Botswana
Brasil
Brunei darussalam
Bulgaria
Burkina faso
Burundi
Cabo verde
Camboya
Camerun
Canada
Chad
Chile
China
Chipre
Colombia
Comoros
Corea
Costa rica
Cote d´ivoire
Croacia
Cuba
Dinamarca
Djibouti
Dominica
East timor
Ecuador
Egipto
El salvador
Emiratos arabes unidos
Eritrea
Escocia
Eslovaquia
Eslovenia
España
Estados federados de micronesia
Estados unidos
Estonia
Etiopia
Fiji
Filipinas
Finlandia
Francia
Gabon
Gambia
Georgia
Ghana
Gibraltar
Grecia
Grenada
Groenlandia
Guadalupe
Guam
Guatemala
Guayana britanica
Guinea
Guinea ecuatorial
Guinea francesa
Guinea-bissau
Haiti
Holanda
Honduras
Hong kong
Hungria
India
Indonesia
Irak
Iran
Irlanda
Isla bouvet
Isla cocos (keeling)
Isla cook
Isla mauricio
Isla navidad
Isla norfolk
Islandia
Islas caiman
Islas falkland (malvinas)
Islas faroe
Islas georgia del sur y sandwich
Islas heard and mc donald
Islas marshall
Islas northern mariana
Islas salomon
Islas svalbard and jan mayen
Islas turks and caicos
Islas united states minor outlyi
Islas virgenes (britanicas)
Islas virgenes (u.s.a.)
Islas wallis and futuna
Israel
Italia
Jamaica
Japon
Jordania
Kazakhstan
Kenia
Kiribati
Kuwait
Kyrgyzstan
Lesoto
Letonia
Libano
Liberia
Libia arab jamahiriya
Liechtenstein
Lituania
Luxemburgo
Macao
Macedonia
Madagascar
Malasia
Malawi
Maldives
Mali
Malta
Marruecos
Martinica
Mauritania
Mayotte
Mexico
Monaco
Mongolia
Monserrat
Morocco
Mozambique
Myanmar
Namibia
Nauru
Nepal
Nicaragua
Niger
Nigeria
Niue
Noruega
Nueva caledonia
Nueva zelanda
Oman
Pakistan
Palau
Panama
Papua new guinea
Paraguay
Peru
Pitcairn
Polinesia francesa
Polonia
Portugal
Posesiones gran bretaña
Posesiones u.s.a.
Puerto rico
Qatar
Reino unido
Republica checa
Republica de africa central
Republica de cabo verde
Republica de congo
Republica de corea
Republica de moldova
Republica democratica de laos
Republica democratica del congo
Republica dominicana
Reunion
Ruanda
Rumania
Rusia
Sahara occidental
Saint kitts and nevis
Samoa
Samoa americana
San marino
San tomas y principe
San vincent and the grenadines
Santa lucia
Senegal
Serbia
Seychelles
Sierra leona
Singapur
Siria
Somalia
Sri lanka
St. helena
St. pierre and miquelon
Sudafrica
Sudan
Suecia
Suiza
Surinam
Swaziland
Tailandia
Taiwan republica de china
Tajikistan
Tanzania
Territorio de indias britanicas
Togo
Tokelau
Tonga
Trinidad and tobago
Tunisia
Turkmenistan
Turquia
Tuvalu
Ucrania
Uganda
Uruguay
Uzbekistan
Vanuatu
Vaticano
Venezuela
Vietnam
Yemen
Yugoslavia
Zambia
Zimbawe
Lebanon
Paises bajos
A coruña
Alava
Albacete
Alicante
Almeria
Asturias
Avila
Badajoz
Balears
Barcelona
Bizkaia
Burgos
Caceres
Cadiz
Cantabria
Castellon
Ceuta
Ciudad real
Cordoba
Cuenca
Girona
Granada
Guadalajara
Guipuzcoa
Huelva
Huesca
Jaen
La rioja
Las palmas
Leon
Lleida
Lugo
Madrid
Malaga
Melilla
Murcia
Navarra
Ourense
Palencia
Pontevedra
Salamanca
Segovia
Sevilla
Soria
Tarragona
Tenerife
Teruel
Toledo
Valencia
Valladolid
Zamora
Zaragoza
-- No procede --
Deseo recibir información sobre productos y promociones especiales de Elsevier por correo electrónico
Deseo recibir información sobre productos y promociones especiales de los partners de Elsevier por correo electrónico
Acepto la Política de Privacidad y los términos y condiciones
* Campos obligatorios
Además del acceso temporal al documento, este le será enviado por correo electrónico.
Atención al cliente
Teléfono
Llamadas desde España
932 415 960
Llamadas desde el extranjero
+34 932 415 960
Horario de 9 a 18h. excepto los meses de julio y agosto que será de 9 a 15h.

Suscríbase a la newsletter

Artículos destacados
Publique en
Revista Clínica Española
Artículos de acceso gratuito
Valor de la ecografía multimodal en la evaluación...
Rev Clin Esp. 2024;224:437-44
Preguntas PICO y metodología DELPHI para mejorar el...
Rev Clin Esp. 2024;224:272-80
COVID-19 y Argumentum ad...
Rev Clin Esp. 2020;220:457
Congresos
45º Congreso de la Sociedad Española de Medicina Interna (SEMI) - Las Palmas
Ver más
Revista Clínica Española se adhiere a los principios y procedimientos dictados por el Committee on Publication Ethics (COPE)
www.publicationethics.org.
Idiomas
Revista Clínica Española
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?