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Navarro-Triviño, M. Moreno-Higueras" "autores" => array:2 [ 0 => array:4 [ "nombre" => "F.J." "apellidos" => "Navarro-Triviño" "email" => array:1 [ 0 => "fntmed@gmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "*" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "M." "apellidos" => "Moreno-Higueras" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio de Dermatología y Venereología, Hospital Universitario San Cecilio, Granada, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicio de Medicina Interna, Hospital Universitario San Cecilio, Granada, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Queratodermia y afectación dental" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 919 "Ancho" => 1674 "Tamanyo" => 177762 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0005" "detalle" => "Figure " "rol" => "short" ] ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">A 59-year-old male was referred for palmoplantar keratoderma associated with dental issues. The patient’s sister had similar lesions, but these were never assessed. The physical examination showed multifocal hyperkeratotic plaques on both palms (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>A) and bottoms of the feet (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>B). Severe periodontology dental symptoms were associated (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>C), including loose teeth, frequent bleeding of the gums, and loss of permanent teeth. Papillon-Lefèvre syndrome was suspected and confirmed through genetic study, showing mutation of the cathepsin C gene (chromosome 11q14). Acitretin 10 mg 2× per day was prescribed. The patient was referred to the maxillofacial surgery department for evaluation of the periodontal involvement.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">Papillon-Lefèvre syndrome is an uncommon autosomal recessive disorder characterised by destructive periodontal disease starting in infancy and palmoplantar keratoderma and frequent cutaneous pyogenic and systemic infections.</p><p id="par0015" class="elsevierStylePara elsevierViewall">Haneke described three criteria for classifying a case as Papillon-Lefèvre syndrome: (1) palmoplantar hyperkeratosis; (2) autosomal recessive trait, and (3) loss of deciduous and permanent teeth.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2019-12-02" "fechaAceptado" => "2020-03-01" "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Navarro-Triviño FJ, Moreno-Higueras M. 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Rev Clin Esp. 2022;222:54–55.</p>" ] ] "multimedia" => array:1 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 919 "Ancho" => 1674 "Tamanyo" => 177762 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0005" "detalle" => "Figure " "rol" => "short" ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/22548874/0000022200000001/v1_202201050658/S2254887421001211/v1_202201050658/en/main.assets" "Apartado" => array:4 [ "identificador" => "71811" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Medicine in images" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/22548874/0000022200000001/v1_202201050658/S2254887421001211/v1_202201050658/en/main.pdf?idApp=WRCEE&text.app=https://revclinesp.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2254887421001211?idApp=WRCEE" ]