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The Spanish National Institute of Toxicology treats only 30&#37; of these consultations<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a>&#59; therefore&#44; the information they record on these episodes is clearly insufficient&#46; In the US&#44; cases of poisoning are treated mostly by telephone and recorded by poison centers&#46;<a class="elsevierStyleCrossRefs" href="#bib0025"><span class="elsevierStyleSup">5&#8211;7</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">To this respect&#44; research aimed at furthering our understanding of this type of event can be a useful tool for improving the care provided and the prevention measures to be implemented&#46;<a class="elsevierStyleCrossRefs" href="#bib0040"><span class="elsevierStyleSup">8&#44;9</span></a> Therefore&#44; the aim of this study was to assess the prevalence of acute poisonings treated in 3 secondary hospitals over 5 years&#46; We analyzed the demographic characteristics&#44; types of poisoning&#44; toxins ingested&#44; seasonal variations and recurrence data regarding patients who experienced new poisoning events of similar characteristics&#44; among others&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0070">Methodology</span><p id="par0015" class="elsevierStylePara elsevierViewall">We conducted a descriptive&#44; observational retrospective study based on information obtained after completing a questionnaire on data<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">10</span></a> extracted from the medical records of the patients treated in the hospital EDs of 3 secondary hospitals belonging to the Murcian Department of Health &#40;Murcia&#44; Spain&#41; from 2013 to 2017&#46; The centers were located in various areas of Murcia&#46; Hospital 1 &#40;H1&#41;&#44; which covered a healthcare area of 87&#44;000 inhabitants&#44; was located on the coast and therefore had a significant tourist influence and thus a notable seasonal nature&#46; Hospital 2 &#40;H2&#41;&#44; which included a healthcare area of 173&#44;000 inhabitants&#44; was located in an eminently rural area&#46; Hospital 3 &#40;H3&#41;&#44; located in a major urban nucleus&#44; covered a healthcare area of 250&#44;000 inhabitants&#46; After anonymizing the cases&#44; we analyzed the data regarding the date of the event&#44; age&#44; sex&#44; prior care&#44; type of poisoning and toxin&#44; recurrence&#44; time in contact with the toxin&#44; care received and destination after the ED care&#46; The inclusion criteria were male and female patients of all ages and a diagnosis of acute poisoning &#40;provided it was established based on the case history or clinical symptoms&#41;&#46; We also included cases that had no initial clinical diagnosis of poisoning but whose poisoning was subsequently demonstrated by laboratory tests&#46; The study limitations were related to the lack of diagnostic coding of the patients treated in the EDs&#44; which could have resulted in the loss of cases&#46; To compare the nominal-nominal variables&#44; we employed Pearson&#8217;s chi-squared test&#46; For the ordinal-nominal variables&#44; we employed the Kruskal&#8211;Wallis test for independent K samples&#46; We considered a p-value &#60;&#46;05 statistically significant&#46; For the data analysis&#44; we employed the statistical package SPSS v24 for Windows&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0075">Results</span><p id="par0020" class="elsevierStylePara elsevierViewall"><a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a> shows the number of emergencies and the cases of acute poisoning treated in the 3 hospitals &#40;the subject of the study&#41; for the 5 years of sampling&#46; A total of 1&#44;141&#44;361 cases were treated during the study period&#44; 0&#46;51&#37; &#40;n&#8239;&#61;&#8239;5870&#41; of which corresponded to acute poisoning&#46; There were no relevant differences observed from one year to the next&#46; The prevalence of acute poisonings treated in H1&#44; H2 and H3 was 0&#46;37&#37;&#44; 0&#46;22&#37; and 0&#46;91&#37;&#44; respectively&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><p id="par0025" class="elsevierStylePara elsevierViewall"><a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a> shows the temporal distribution and type of poisonings treated in each of the study areas&#46; The data reveal significant differences &#40;p&#8239;&#60;&#8239;&#46;05&#41; between the type of poisoning and the number of cases in most months&#46; In H1&#44; the percentage of poisonings cases related to alcohol had a high upturn in the summer months &#40;60&#46;53&#37; and 61&#46;27&#37; in July and August&#44; respectively&#41;&#46; In H3&#44; however&#44; there was a clear reduction &#40;28&#46;22&#37; and 37&#46;20&#37; in July and August&#44; respectively&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0030" class="elsevierStylePara elsevierViewall">When analyzing the type of poisoning by age range &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41;&#44; we detected significant differences &#40;p&#8239;&#60;&#8239;&#46;05&#41; in the 3 hospitals and in all categories&#44; except for the 0&#8211;30-year range&#46; Alcohol was the main cause of poisoning for the 15&#8211;30-year age group &#40;in the 3 hospitals&#41;&#44; followed by accidental poisonings and voluntary poisoning for suicidal purposes&#46; In H3 &#40;the urban hospital&#41;&#44; the voluntary poisonings exceeded the accidental&#46;</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0035" class="elsevierStylePara elsevierViewall">In the 31&#8211;45-year age range&#44; alcohol poisoning had the highest prevalence in the 3 hospitals &#40;65&#46;03&#37;&#44; 53&#46;97&#37; and 61&#46;52&#37; in H1&#44; H2 and H3&#44; respectively&#41;&#44; followed by voluntary poisonings for suicidal purposes &#40;15&#46;51&#37;&#44; 32&#46;70&#37; and 17&#46;72&#37; in H1&#44; H2 and H3&#44; respectively&#41;&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">In the 46&#8211;60-year age range&#44; alcohol poisoning predominated in H1 and H2 &#40;43&#46;78&#37; and 54&#46;72&#37;&#44; respectively&#41;&#44; followed by voluntary poisonings for suicidal purposes &#40;31&#46;64&#37; and 26&#46;41&#37;&#44; respectively&#41;&#46; In H3&#44; however&#44; voluntary poisonings for suicidal purposes had a higher prevalence than alcohol poisonings &#40;38&#46;80&#37; vs&#46; 34&#46;18&#37;&#41;&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">The data shown in <a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a> show that 55&#46;77&#37; and 44&#46;23&#37; of the poisonings occurred in male and female patients&#44; respectively&#46; There were significant differences &#40;p&#8239;&#60;&#8239;&#46;05&#41; between the male and female patients in all age ranges&#44; except for the 0&#8211;30-year range&#46; In the 31&#8211;45-year age range&#44; alcohol poisoning had the highest prevalence for both sexes &#40;67&#46;36&#37; and 50&#46;06&#37; for the men and women&#44; respectively&#41;&#44; followed by voluntary poisonings for suicidal purposes&#44; which was higher for the women &#40;30&#46;38&#37;&#41; than for the men &#40;11&#46;91&#37;&#41;&#46; The illicit drug overdose rate was higher for the men &#40;12&#46;16&#37;&#41; than for the women &#40;6&#46;12&#37;&#41;&#46;</p><p id="par0050" class="elsevierStylePara elsevierViewall">In the 46&#8211;60-year age range&#44; alcohol poisoning still accounted for most of the cases among the men &#40;51&#46;45&#37;&#41;&#44; followed by voluntary poisonings for suicidal purposes &#40;20&#46;29&#37;&#41;&#44; illicit drug overdosing &#40;16&#46;15&#37;&#41; and accidental poisonings &#40;10&#46;77&#37;&#41;&#46; However&#44; voluntary poisonings for suicidal purposes accounted for most of the cases among women &#40;54&#46;76&#37;&#41;&#44; followed by alcohol poisoning &#40;23&#46;81&#37;&#41;&#44; accidental poisoning &#40;16&#46;67&#37;&#41; and illicit drug overdosing &#40;3&#46;57&#37;&#41;&#46;</p><p id="par0055" class="elsevierStylePara elsevierViewall">In the 61&#8211;75-year age range&#44; alcohol poisoning remained predominant among the men &#40;59&#46;22&#37;&#41; but dropped to third position for women &#40;23&#46;43&#37;&#41;&#46; Voluntary poisonings for suicidal purposes was the leading cause for women &#40;49&#46;32&#37;&#41; and the second leading cause for men &#40;18&#46;62&#37;&#41;&#46; Accidental poisonings was the second leading cause for women &#40;24&#46;78&#37;&#41; and the third for men &#40;16&#46;31&#37;&#41;&#46;</p><p id="par0060" class="elsevierStylePara elsevierViewall">In the 76&#8211;90-year age range&#44; alcohol was still the most common type of poisoning among men &#40;47&#46;65&#37;&#41;&#44; while for women it was accidental poisoning &#40;66&#46;67&#37;&#41;&#46;</p><p id="par0065" class="elsevierStylePara elsevierViewall"><a class="elsevierStyleCrossRef" href="#tbl0010">Table 2</a> shows the number of recurrent cases according to the type of toxin and sex&#46; The most prevalent poisonings for both sexes were from alcohol&#44; medication&#44; insect bites and illicit drugs&#46; For medicinal products&#44; benzodiazepines were the most widely used substances&#46; For recreational drugs&#44; cocaine generated the most cases&#44; followed by cannabis&#46; The results also reveal significant differences between men and women in terms of recurrence poisonings by alcohol &#40;p&#8239;&#61;&#8239;&#46;000&#41;&#44; benzodiazepines &#40;p&#8239;&#61;&#8239;&#46;010&#41;&#44; anticoagulants &#40;p&#8239;&#61;&#8239;&#46;011&#41; and heroin &#40;p&#8239;&#61;&#8239;&#46;026&#41;&#46; The men with recurrent poisonings are usually those with poisoning by alcohol &#40;62&#46;73&#37;&#41;&#44; benzodiazepine &#40;13&#46;32&#37;&#41;&#44; cocaine &#40;9&#46;83&#37;&#41; and cannabis &#40;3&#46;57&#37;&#41;&#44; while for women&#44; these poisonings were from benzodiazepine &#40;45&#46;41&#37;&#41;&#44; alcohol &#40;30&#46;11&#37;&#41;&#44; antidepressants &#40;6&#46;44&#37;&#41; and cocaine &#40;5&#46;80&#37;&#41;&#46;</p><elsevierMultimedia ident="tbl0010"></elsevierMultimedia><p id="par0070" class="elsevierStylePara elsevierViewall">The patients&#8217; origin&#44; time in contact with the toxin to the first treatment and the destination after emergency care are shown in <a class="elsevierStyleCrossRef" href="#tbl0015">Table 3</a>&#46; The overall results show a relationship between the time in contact with the toxin and the patient&#8217;s origin before the ED care &#40;p&#8239;&#61;&#8239;&#46;000&#41;&#44; although fewer cases were observed when the origin was another hospital &#40;n&#8239;&#61;&#8239;99&#41;&#46; Some 37&#46;96&#37; of the patients came from the ED itself&#44; 23&#46;73&#37; came from primary care&#44; and 22&#46;74&#37; had an outpatient origin&#46; Most of the patients were treated within the first hour of contact with the toxin &#40;69&#46;34&#37;&#41;&#44; 15&#46;94&#37; were treated between the first and second hour&#44; and 7&#46;26&#37; were treated between the second and third hour of contact&#46;</p><elsevierMultimedia ident="tbl0015"></elsevierMultimedia><p id="par0075" class="elsevierStylePara elsevierViewall">Moreover&#44; the statistical test applied between the destination after the ED care and the patients&#8217; origin shows that there was a relationship between the 2 variables &#40;p&#8239;&#61;&#8239;&#46;000&#41;&#46; Regardless of the patients&#8217; origin&#44; 65&#46;69&#37; were discharged within 12&#8239;h&#44; 10&#46;09&#37; required hospitalization &#40;conventional ward&#44; ICU or psychiatry&#41;&#44; 2&#46;82&#37; fled&#44; 2&#46;74&#37; requested a voluntary discharge&#44; and 0&#46;88&#37; died&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0080">Discussion</span><p id="par0080" class="elsevierStylePara elsevierViewall">The mean prevalence of acute poisoning treated in the EDs of the 3 hospitals analyzed during the study period was 0&#46;51&#37;&#46; H2 &#40;located in a rural area&#41; had fewer poisoning cases &#40;0&#46;22&#37;&#41;&#44; while H3 &#40;located in an urban area&#41; had more &#40;0&#46;91&#37;&#41;&#46; H1 &#40;located in a highly touristic area&#41; had a prevalence of 0&#46;37&#37; during the summer&#46; These data differ from those published by other authors in which the rates remained similar &#40;0&#46;66&#37;&#44;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">10</span></a> 0&#46;67&#37;<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">11</span></a> and 0&#46;68&#37;<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">12</span></a>&#41;&#46;</p><p id="par0085" class="elsevierStylePara elsevierViewall">The data reveal certain seasonal variations over the course of the year&#44; especially in H1&#46; In this hospital&#44; the rates were very similar &#40;0&#46;32&#37; and 0&#46;38&#37; for May and November&#44; respectively&#41;&#46; However&#44; H1 experienced an upturn during the summer months &#40;0&#46;44&#37; for both July and August&#41;&#46; This result could be due to the fact that this hospital is located in an area with considerable tourism and whose population increases in the summer&#46; These differences are more obvious in alcohol poisoning&#46; In H2 &#40;0&#46;13&#37; and 0&#46;30&#37; for May and September&#44; respectively&#41; and H3 &#40;0&#46;75&#37; and 1&#46;12&#37; for July and June&#44; respectively&#41;&#44; the seasonal variations are not as noticeable&#46; However&#44; variations are manifested in alcohol poisoning&#44; given that they increase during local festivities and decrease during the summer&#44; quite possibly due to the fact that these areas experience a vacation exodus in the summer months&#46; These data reveal that alcohol consumption is highly ingrained in popular traditions in Spain&#44; with alcohol being the most prevalent toxin for more than 30 years&#46;<a class="elsevierStyleCrossRefs" href="#bib0065"><span class="elsevierStyleSup">13&#44;14</span></a></p><p id="par0090" class="elsevierStylePara elsevierViewall">In terms of age groups and type of poisoning&#44; the results indicate that the highest number of poisonings occurred in the 31&#8211;60-year age group&#44; which is consistent with other studies performed on the national level&#46;<a class="elsevierStyleCrossRefs" href="#bib0050"><span class="elsevierStyleSup">10&#44;12</span></a> In this age range&#44; alcohol poisoning is most prevalent among men&#46; For women 46 years or older&#44; poisoning for suicidal purposes was the most prevalent&#44; as shown by other multicenter studies performed in Asturias<a class="elsevierStyleCrossRef" href="#bib0075"><span class="elsevierStyleSup">15</span></a> and Catalonia&#46;<a class="elsevierStyleCrossRef" href="#bib0080"><span class="elsevierStyleSup">16</span></a> The lack of pediatric cases &#40;0&#8211;15 years&#41; limits the comparison with other studies that included this age range&#46; Alcohol was the main cause of poisoning for the 15&#8211;30-year age range in the 3 hospitals&#44; which again shows the need to boost outreach campaigns to decrease alcohol consumption among the young&#46;</p><p id="par0095" class="elsevierStylePara elsevierViewall">Most patients are admitted to EDs within the first hours after contact with the toxin&#44; which favors the treatment&#44; especially for medicinal products where prompt digestive decontamination can be performed&#46; Generally&#44; the first intervention with the poisoned patient is performed in the hospital ED&#44; although a considerable number of patients previously attend primary care or are treated by outpatient emergency services such as 061 &#40;the Spanish equivalent of 911 &#40;US&#41; &#47; 999 &#40;UK&#41;&#41;&#46; The HISPATOX<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> study conducted in 2006 also showed that most poisonings were treated directly in hospital EDs &#40;51&#46;2&#37;&#41;&#46;</p><p id="par0100" class="elsevierStylePara elsevierViewall">In terms of patient destination after ED treatment&#44; this study revealed that&#44; in less than 12&#8239;h&#44; most patients were discharged to their home &#40;65&#46;65&#37;&#41;&#44; a rate much higher than that recorded by other authors &#40;53&#44;50&#37;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> and 58&#46;84&#37;<a class="elsevierStyleCrossRef" href="#bib0070"><span class="elsevierStyleSup">14</span></a>&#41;&#46; The small number of intensive care admissions is shared with other studies&#44;<a class="elsevierStyleCrossRefs" href="#bib0020"><span class="elsevierStyleSup">4&#44;12&#44;15</span></a> which could be related to the early care administered to patients &#40;&#60;12&#8239;h&#41;&#46; The low mortality rate &#40;0&#46;08&#37;&#41; has also been noted in other studies &#40;0&#46;15&#37;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> and 0&#46;19&#37;<a class="elsevierStyleCrossRef" href="#bib0075"><span class="elsevierStyleSup">15</span></a>&#41;&#46;</p><p id="par0105" class="elsevierStylePara elsevierViewall">In terms of differences by sex&#44; this study&#8217;s data indicate that men have a higher prevalence of poisoning than women &#40;55&#46;77&#37; vs&#46; 44&#46;23&#37;&#41;&#46; These data are consistent with that of other studies&#44; such as the one conducted by Carpintero et al&#46; in La Rioja &#40;Spain&#41; in 1998<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">11</span></a> but differ from those of the study by Gonz&#225;lez-Fern&#225;ndez et al&#46; in Asturias &#40;Spain&#41; in 2007<a class="elsevierStyleCrossRef" href="#bib0075"><span class="elsevierStyleSup">15</span></a> in which the differences were greater &#40;66&#46;80&#37; vs&#46; 33&#46;20&#37;&#41; and those of the recently published study by Puiguriguer-Ferrando et al&#46; in the Balearic Islands in which the rates were similar &#40;50&#46;64&#37; vs&#46; 49&#46;36&#37;&#41;&#46; The results also revealed that alcohol&#44; benzodiazepines&#44; insect bites and illicit drugs &#40;cocaine and cannabis<a class="elsevierStyleCrossRef" href="#bib0090"><span class="elsevierStyleSup">17</span></a>&#41; are the toxins of highest prevalence for both sexes&#44; although men have more recurrences with alcohol&#44; while women have more with benzodiazepines&#46; Burillo<a class="elsevierStyleCrossRef" href="#bib0070"><span class="elsevierStyleSup">14</span></a> reached the same conclusions regarding recurrence&#44; which can occur given the ease in obtaining this type of toxin &#40;alcohol and drugs<a class="elsevierStyleCrossRef" href="#bib0095"><span class="elsevierStyleSup">18</span></a>&#41;&#44; which increases the possibilities of another acute poisoning&#46;</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0085">Conclusions</span><p id="par0110" class="elsevierStylePara elsevierViewall">The number of treated acute poisoning cases depends on the hospital location&#44; such that the urban hospital had the highest prevalence&#44; while the rural hospital recorded the lowest number of cases&#46; This situation is also revealed by the seasonal nature of poisonings&#44; especially in the hospital located in the highly touristic area during the summer&#44; which is therefore subject to significant population variations throughout the year and&#44; conversely&#44; in those that experience a vacation exodus&#46; Alcohol is the main cause of poisonings in all of the hospitals analyzed&#46; Males had a higher number of poisonings than females &#40;in all age ranges&#41;&#44; with alcohol once again the main cause&#46; For women 46 years or older&#44; voluntary poisonings with benzodiazepines exceed the alcohol poisonings&#46; A significant number of patients presented previous poisonings&#44; especially men due to alcohol and women due to benzodiazepines&#46; Cocaine was the most consumed illicit drug&#46; These types of events were mostly treated by hospital EDs&#44; and most patients were discharged within the first 12&#8239;h&#46; Finally&#44; the considerable social roots of alcohol consumption for all major age groups should therefore impel us to seek measures to reduce this type of consumption&#46;</p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0090">Conflicts of interest</span><p id="par0115" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflicts of interest&#46;</p></span></span>"
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    "fechaRecibido" => "2019-06-07"
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            1 => "Toxic"
            2 => "Epidemiology"
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          "palabras" => array:4 [
            0 => "Intoxicaci&#243;n"
            1 => "T&#243;xico"
            2 => "Epidemiolog&#237;a"
            3 => "Urgencias"
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        "titulo" => "Abstract"
        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Objective</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">To assess the characteristics of acute poisoning cases treated in hospital emergency departments over 5 years&#46;</p></span> <span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Methods</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Retrospective study of acute poisoning cases treated in 3 hospitals between 2013 and 2017 and an analysis of the demographic characteristics&#44; types of poisoning&#44; seasonal variations&#44; care received and recurrence&#46;</p></span> <span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Results</span><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Some 0&#46;51&#37; of all cases treated in the 3 hospitals corresponded to acute poisoning&#46; The percentages varied by hospital location &#40;0&#46;91&#37; urban&#44; 0&#46;37&#37; coastal and 0&#46;22&#37; rural&#41;&#46; Cases of alcohol poisoning had a seasonal character&#44; increasing during the summer on the coast &#40;p&#8239;&#60;&#8239;&#46;05&#41;&#46; There were differences in the type of poisoning &#40;p&#8239;&#60;&#8239;&#46;05&#41; for patients 31 years of age and older in the 3 hospitals&#46; Alcohol represented the largest number of cases in patients 31 years of age and older&#44; except in the rural area where most cases were due to voluntary poisoning in attempted suicide&#46; Men had a higher prevalence of poisoning than women &#40;55&#46;77&#37; vs&#46; 44&#46;23&#37;&#41; for all cases&#46; Alcohol poisoning was in first place for men 30&#8211;75 years&#44; and voluntary poisoning for attempted suicide was first for women&#44; except for those 30&#8211;46 years of age for whom alcohol was also number one&#46; The large number of cases of recurrence were due to alcohol in men &#40;791 cases&#41; and to benzodiazepines in women &#40;528 cases&#41;&#46;</p></span> <span id="abst0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Conclusions</span><p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">The number of cases and the type of poisoning varied according to hospital location&#44; season&#44; patient sex and patient age&#46;</p></span>"
        "secciones" => array:4 [
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        "titulo" => "Resumen"
        "resumen" => "<span id="abst0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Objetivo</span><p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">Evaluar las caracter&#237;sticas de las intoxicaciones agudas atendidas en urgencias hospitalarias durante cinco a&#241;os&#46;</p></span> <span id="abst0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">M&#233;todo</span><p id="spar0060" class="elsevierStyleSimplePara elsevierViewall">Estudio retrospectivo de las intoxicaciones agudas asistidas en tres hospitales entre 2013 y 2017 y an&#225;lisis de las caracter&#237;sticas demogr&#225;ficas&#44; tipos de intoxicaci&#243;n&#44; variaciones estacionales&#44; asistencia recibida y reincidencia&#46;</p></span> <span id="abst0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Resultados</span><p id="spar0065" class="elsevierStyleSimplePara elsevierViewall">El 0&#44;51&#37; de los casos atendidos en los tres hospitales se correspondieron a intoxicaciones agudas&#46; Los porcentajes var&#237;an seg&#250;n la localizaci&#243;n del hospital &#40;0&#44;91&#37; urbano&#44; 0&#44;37&#37; en zona de costa y 0&#44;22&#37; rural&#46; Las intoxicaciones alcoh&#243;licas presentan cierto car&#225;cter estacional&#44; aumentando en &#233;poca estival en la costa &#40;<span class="elsevierStyleItalic">p</span>&#8239;&#60;&#8239;0&#44;05&#41;&#46; A partir de los 31 a&#241;os de edad existen diferencias en cuanto al tipo de intoxicaci&#243;n &#40;<span class="elsevierStyleItalic">p</span>&#8239;&#60;&#8239;0&#44;05&#41; en los 3 hospitales&#46; El alcohol siempre representa el mayor n&#250;mero de casos a partir de los 31 a&#241;os&#44; excepto en la zona rural que son las intoxicaciones voluntarias con fines autol&#237;ticos&#46; Los hombres muestran mayor prevalencia que las mujeres &#40;55&#44;77&#37; vs 44&#44;23&#37;&#41; para el conjunto de los casos&#46; Las intoxicaciones alcoh&#243;licas est&#225;n en primer lugar en hombres de 30 a 75 a&#241;os y las voluntarias con fines autol&#237;ticos en mujeres&#44; excepto de 30 a 46 a&#241;os que tambi&#233;n es por alcohol&#46; El mayor n&#250;mero de casos reincidentes se producen por el alcohol en hombres &#40;791 casos&#41; y por benzodiacepinas en mujeres &#40;528 casos&#41;&#46;</p></span> <span id="abst0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Conclusiones</span><p id="spar0070" class="elsevierStyleSimplePara elsevierViewall">El n&#250;mero y el tipo de intoxicaci&#243;n var&#237;a en funci&#243;n de la ubicaci&#243;n del hospital&#44; la &#233;poca del a&#241;o&#44; el sexo y la edad de los pacientes&#46;</p></span>"
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                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t\ttop\n
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                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t">&#46;559&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
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                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">1&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">1&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#46;121&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Plants&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">na&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Gases&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t\ttop\n
                  \t\t\t\t">111&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#46;102&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Medication ns&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">11&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
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                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">33&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#46;092&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Morphine&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
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                  \t\t\t\t">1&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
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                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">58&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#46;960&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Benzodiazepines&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">168&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">209&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">282&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">528&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1187&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#46;01&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Antidepressants&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">20&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">24&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">40&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">47&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">131&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#46;955&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Antihypertensives&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">17&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">22&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">45&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#46;769&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Paracetamol&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">19&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">17&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">36&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">81&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#46;995&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Insulin&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">12&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">13&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">31&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#46;411&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Anticoagulants&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">135&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">148&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">289&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#46;011&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Analgesics&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
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                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
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                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">1975&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">5870&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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Original article
Prevalence of acute poisoning treated in 3 hospitals in Southeast Spain
Prevalencia de las intoxicaciones agudas asistidas en 3 hospitales del sureste español
M. Baezaa,b, A. Muñoz-Ortegac, N. Velab,
Corresponding author
nvela@ucam.edu

Corresponding author.
a Programa de doctorado en Ciencias de la Salud, Universidad Católica de Murcia (UCAM), Murcia, Spain
b Facultad de Ciencias de la Salud, Universidad Católica de Murcia (UCAM), Murcia, Spain
c Facultad de C.C. Politécnicas, Universidad Católica de Murcia (UCAM), Murcia, Spain
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The Spanish National Institute of Toxicology treats only 30&#37; of these consultations<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a>&#59; therefore&#44; the information they record on these episodes is clearly insufficient&#46; In the US&#44; cases of poisoning are treated mostly by telephone and recorded by poison centers&#46;<a class="elsevierStyleCrossRefs" href="#bib0025"><span class="elsevierStyleSup">5&#8211;7</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">To this respect&#44; research aimed at furthering our understanding of this type of event can be a useful tool for improving the care provided and the prevention measures to be implemented&#46;<a class="elsevierStyleCrossRefs" href="#bib0040"><span class="elsevierStyleSup">8&#44;9</span></a> Therefore&#44; the aim of this study was to assess the prevalence of acute poisonings treated in 3 secondary hospitals over 5 years&#46; We analyzed the demographic characteristics&#44; types of poisoning&#44; toxins ingested&#44; seasonal variations and recurrence data regarding patients who experienced new poisoning events of similar characteristics&#44; among others&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0070">Methodology</span><p id="par0015" class="elsevierStylePara elsevierViewall">We conducted a descriptive&#44; observational retrospective study based on information obtained after completing a questionnaire on data<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">10</span></a> extracted from the medical records of the patients treated in the hospital EDs of 3 secondary hospitals belonging to the Murcian Department of Health &#40;Murcia&#44; Spain&#41; from 2013 to 2017&#46; The centers were located in various areas of Murcia&#46; Hospital 1 &#40;H1&#41;&#44; which covered a healthcare area of 87&#44;000 inhabitants&#44; was located on the coast and therefore had a significant tourist influence and thus a notable seasonal nature&#46; Hospital 2 &#40;H2&#41;&#44; which included a healthcare area of 173&#44;000 inhabitants&#44; was located in an eminently rural area&#46; Hospital 3 &#40;H3&#41;&#44; located in a major urban nucleus&#44; covered a healthcare area of 250&#44;000 inhabitants&#46; After anonymizing the cases&#44; we analyzed the data regarding the date of the event&#44; age&#44; sex&#44; prior care&#44; type of poisoning and toxin&#44; recurrence&#44; time in contact with the toxin&#44; care received and destination after the ED care&#46; The inclusion criteria were male and female patients of all ages and a diagnosis of acute poisoning &#40;provided it was established based on the case history or clinical symptoms&#41;&#46; We also included cases that had no initial clinical diagnosis of poisoning but whose poisoning was subsequently demonstrated by laboratory tests&#46; The study limitations were related to the lack of diagnostic coding of the patients treated in the EDs&#44; which could have resulted in the loss of cases&#46; To compare the nominal-nominal variables&#44; we employed Pearson&#8217;s chi-squared test&#46; For the ordinal-nominal variables&#44; we employed the Kruskal&#8211;Wallis test for independent K samples&#46; We considered a p-value &#60;&#46;05 statistically significant&#46; For the data analysis&#44; we employed the statistical package SPSS v24 for Windows&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0075">Results</span><p id="par0020" class="elsevierStylePara elsevierViewall"><a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a> shows the number of emergencies and the cases of acute poisoning treated in the 3 hospitals &#40;the subject of the study&#41; for the 5 years of sampling&#46; A total of 1&#44;141&#44;361 cases were treated during the study period&#44; 0&#46;51&#37; &#40;n&#8239;&#61;&#8239;5870&#41; of which corresponded to acute poisoning&#46; There were no relevant differences observed from one year to the next&#46; The prevalence of acute poisonings treated in H1&#44; H2 and H3 was 0&#46;37&#37;&#44; 0&#46;22&#37; and 0&#46;91&#37;&#44; respectively&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><p id="par0025" class="elsevierStylePara elsevierViewall"><a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a> shows the temporal distribution and type of poisonings treated in each of the study areas&#46; The data reveal significant differences &#40;p&#8239;&#60;&#8239;&#46;05&#41; between the type of poisoning and the number of cases in most months&#46; In H1&#44; the percentage of poisonings cases related to alcohol had a high upturn in the summer months &#40;60&#46;53&#37; and 61&#46;27&#37; in July and August&#44; respectively&#41;&#46; In H3&#44; however&#44; there was a clear reduction &#40;28&#46;22&#37; and 37&#46;20&#37; in July and August&#44; respectively&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0030" class="elsevierStylePara elsevierViewall">When analyzing the type of poisoning by age range &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41;&#44; we detected significant differences &#40;p&#8239;&#60;&#8239;&#46;05&#41; in the 3 hospitals and in all categories&#44; except for the 0&#8211;30-year range&#46; Alcohol was the main cause of poisoning for the 15&#8211;30-year age group &#40;in the 3 hospitals&#41;&#44; followed by accidental poisonings and voluntary poisoning for suicidal purposes&#46; In H3 &#40;the urban hospital&#41;&#44; the voluntary poisonings exceeded the accidental&#46;</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0035" class="elsevierStylePara elsevierViewall">In the 31&#8211;45-year age range&#44; alcohol poisoning had the highest prevalence in the 3 hospitals &#40;65&#46;03&#37;&#44; 53&#46;97&#37; and 61&#46;52&#37; in H1&#44; H2 and H3&#44; respectively&#41;&#44; followed by voluntary poisonings for suicidal purposes &#40;15&#46;51&#37;&#44; 32&#46;70&#37; and 17&#46;72&#37; in H1&#44; H2 and H3&#44; respectively&#41;&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">In the 46&#8211;60-year age range&#44; alcohol poisoning predominated in H1 and H2 &#40;43&#46;78&#37; and 54&#46;72&#37;&#44; respectively&#41;&#44; followed by voluntary poisonings for suicidal purposes &#40;31&#46;64&#37; and 26&#46;41&#37;&#44; respectively&#41;&#46; In H3&#44; however&#44; voluntary poisonings for suicidal purposes had a higher prevalence than alcohol poisonings &#40;38&#46;80&#37; vs&#46; 34&#46;18&#37;&#41;&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">The data shown in <a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a> show that 55&#46;77&#37; and 44&#46;23&#37; of the poisonings occurred in male and female patients&#44; respectively&#46; There were significant differences &#40;p&#8239;&#60;&#8239;&#46;05&#41; between the male and female patients in all age ranges&#44; except for the 0&#8211;30-year range&#46; In the 31&#8211;45-year age range&#44; alcohol poisoning had the highest prevalence for both sexes &#40;67&#46;36&#37; and 50&#46;06&#37; for the men and women&#44; respectively&#41;&#44; followed by voluntary poisonings for suicidal purposes&#44; which was higher for the women &#40;30&#46;38&#37;&#41; than for the men &#40;11&#46;91&#37;&#41;&#46; The illicit drug overdose rate was higher for the men &#40;12&#46;16&#37;&#41; than for the women &#40;6&#46;12&#37;&#41;&#46;</p><p id="par0050" class="elsevierStylePara elsevierViewall">In the 46&#8211;60-year age range&#44; alcohol poisoning still accounted for most of the cases among the men &#40;51&#46;45&#37;&#41;&#44; followed by voluntary poisonings for suicidal purposes &#40;20&#46;29&#37;&#41;&#44; illicit drug overdosing &#40;16&#46;15&#37;&#41; and accidental poisonings &#40;10&#46;77&#37;&#41;&#46; However&#44; voluntary poisonings for suicidal purposes accounted for most of the cases among women &#40;54&#46;76&#37;&#41;&#44; followed by alcohol poisoning &#40;23&#46;81&#37;&#41;&#44; accidental poisoning &#40;16&#46;67&#37;&#41; and illicit drug overdosing &#40;3&#46;57&#37;&#41;&#46;</p><p id="par0055" class="elsevierStylePara elsevierViewall">In the 61&#8211;75-year age range&#44; alcohol poisoning remained predominant among the men &#40;59&#46;22&#37;&#41; but dropped to third position for women &#40;23&#46;43&#37;&#41;&#46; Voluntary poisonings for suicidal purposes was the leading cause for women &#40;49&#46;32&#37;&#41; and the second leading cause for men &#40;18&#46;62&#37;&#41;&#46; Accidental poisonings was the second leading cause for women &#40;24&#46;78&#37;&#41; and the third for men &#40;16&#46;31&#37;&#41;&#46;</p><p id="par0060" class="elsevierStylePara elsevierViewall">In the 76&#8211;90-year age range&#44; alcohol was still the most common type of poisoning among men &#40;47&#46;65&#37;&#41;&#44; while for women it was accidental poisoning &#40;66&#46;67&#37;&#41;&#46;</p><p id="par0065" class="elsevierStylePara elsevierViewall"><a class="elsevierStyleCrossRef" href="#tbl0010">Table 2</a> shows the number of recurrent cases according to the type of toxin and sex&#46; The most prevalent poisonings for both sexes were from alcohol&#44; medication&#44; insect bites and illicit drugs&#46; For medicinal products&#44; benzodiazepines were the most widely used substances&#46; For recreational drugs&#44; cocaine generated the most cases&#44; followed by cannabis&#46; The results also reveal significant differences between men and women in terms of recurrence poisonings by alcohol &#40;p&#8239;&#61;&#8239;&#46;000&#41;&#44; benzodiazepines &#40;p&#8239;&#61;&#8239;&#46;010&#41;&#44; anticoagulants &#40;p&#8239;&#61;&#8239;&#46;011&#41; and heroin &#40;p&#8239;&#61;&#8239;&#46;026&#41;&#46; The men with recurrent poisonings are usually those with poisoning by alcohol &#40;62&#46;73&#37;&#41;&#44; benzodiazepine &#40;13&#46;32&#37;&#41;&#44; cocaine &#40;9&#46;83&#37;&#41; and cannabis &#40;3&#46;57&#37;&#41;&#44; while for women&#44; these poisonings were from benzodiazepine &#40;45&#46;41&#37;&#41;&#44; alcohol &#40;30&#46;11&#37;&#41;&#44; antidepressants &#40;6&#46;44&#37;&#41; and cocaine &#40;5&#46;80&#37;&#41;&#46;</p><elsevierMultimedia ident="tbl0010"></elsevierMultimedia><p id="par0070" class="elsevierStylePara elsevierViewall">The patients&#8217; origin&#44; time in contact with the toxin to the first treatment and the destination after emergency care are shown in <a class="elsevierStyleCrossRef" href="#tbl0015">Table 3</a>&#46; The overall results show a relationship between the time in contact with the toxin and the patient&#8217;s origin before the ED care &#40;p&#8239;&#61;&#8239;&#46;000&#41;&#44; although fewer cases were observed when the origin was another hospital &#40;n&#8239;&#61;&#8239;99&#41;&#46; Some 37&#46;96&#37; of the patients came from the ED itself&#44; 23&#46;73&#37; came from primary care&#44; and 22&#46;74&#37; had an outpatient origin&#46; Most of the patients were treated within the first hour of contact with the toxin &#40;69&#46;34&#37;&#41;&#44; 15&#46;94&#37; were treated between the first and second hour&#44; and 7&#46;26&#37; were treated between the second and third hour of contact&#46;</p><elsevierMultimedia ident="tbl0015"></elsevierMultimedia><p id="par0075" class="elsevierStylePara elsevierViewall">Moreover&#44; the statistical test applied between the destination after the ED care and the patients&#8217; origin shows that there was a relationship between the 2 variables &#40;p&#8239;&#61;&#8239;&#46;000&#41;&#46; Regardless of the patients&#8217; origin&#44; 65&#46;69&#37; were discharged within 12&#8239;h&#44; 10&#46;09&#37; required hospitalization &#40;conventional ward&#44; ICU or psychiatry&#41;&#44; 2&#46;82&#37; fled&#44; 2&#46;74&#37; requested a voluntary discharge&#44; and 0&#46;88&#37; died&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0080">Discussion</span><p id="par0080" class="elsevierStylePara elsevierViewall">The mean prevalence of acute poisoning treated in the EDs of the 3 hospitals analyzed during the study period was 0&#46;51&#37;&#46; H2 &#40;located in a rural area&#41; had fewer poisoning cases &#40;0&#46;22&#37;&#41;&#44; while H3 &#40;located in an urban area&#41; had more &#40;0&#46;91&#37;&#41;&#46; H1 &#40;located in a highly touristic area&#41; had a prevalence of 0&#46;37&#37; during the summer&#46; These data differ from those published by other authors in which the rates remained similar &#40;0&#46;66&#37;&#44;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">10</span></a> 0&#46;67&#37;<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">11</span></a> and 0&#46;68&#37;<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">12</span></a>&#41;&#46;</p><p id="par0085" class="elsevierStylePara elsevierViewall">The data reveal certain seasonal variations over the course of the year&#44; especially in H1&#46; In this hospital&#44; the rates were very similar &#40;0&#46;32&#37; and 0&#46;38&#37; for May and November&#44; respectively&#41;&#46; However&#44; H1 experienced an upturn during the summer months &#40;0&#46;44&#37; for both July and August&#41;&#46; This result could be due to the fact that this hospital is located in an area with considerable tourism and whose population increases in the summer&#46; These differences are more obvious in alcohol poisoning&#46; In H2 &#40;0&#46;13&#37; and 0&#46;30&#37; for May and September&#44; respectively&#41; and H3 &#40;0&#46;75&#37; and 1&#46;12&#37; for July and June&#44; respectively&#41;&#44; the seasonal variations are not as noticeable&#46; However&#44; variations are manifested in alcohol poisoning&#44; given that they increase during local festivities and decrease during the summer&#44; quite possibly due to the fact that these areas experience a vacation exodus in the summer months&#46; These data reveal that alcohol consumption is highly ingrained in popular traditions in Spain&#44; with alcohol being the most prevalent toxin for more than 30 years&#46;<a class="elsevierStyleCrossRefs" href="#bib0065"><span class="elsevierStyleSup">13&#44;14</span></a></p><p id="par0090" class="elsevierStylePara elsevierViewall">In terms of age groups and type of poisoning&#44; the results indicate that the highest number of poisonings occurred in the 31&#8211;60-year age group&#44; which is consistent with other studies performed on the national level&#46;<a class="elsevierStyleCrossRefs" href="#bib0050"><span class="elsevierStyleSup">10&#44;12</span></a> In this age range&#44; alcohol poisoning is most prevalent among men&#46; For women 46 years or older&#44; poisoning for suicidal purposes was the most prevalent&#44; as shown by other multicenter studies performed in Asturias<a class="elsevierStyleCrossRef" href="#bib0075"><span class="elsevierStyleSup">15</span></a> and Catalonia&#46;<a class="elsevierStyleCrossRef" href="#bib0080"><span class="elsevierStyleSup">16</span></a> The lack of pediatric cases &#40;0&#8211;15 years&#41; limits the comparison with other studies that included this age range&#46; Alcohol was the main cause of poisoning for the 15&#8211;30-year age range in the 3 hospitals&#44; which again shows the need to boost outreach campaigns to decrease alcohol consumption among the young&#46;</p><p id="par0095" class="elsevierStylePara elsevierViewall">Most patients are admitted to EDs within the first hours after contact with the toxin&#44; which favors the treatment&#44; especially for medicinal products where prompt digestive decontamination can be performed&#46; Generally&#44; the first intervention with the poisoned patient is performed in the hospital ED&#44; although a considerable number of patients previously attend primary care or are treated by outpatient emergency services such as 061 &#40;the Spanish equivalent of 911 &#40;US&#41; &#47; 999 &#40;UK&#41;&#41;&#46; The HISPATOX<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> study conducted in 2006 also showed that most poisonings were treated directly in hospital EDs &#40;51&#46;2&#37;&#41;&#46;</p><p id="par0100" class="elsevierStylePara elsevierViewall">In terms of patient destination after ED treatment&#44; this study revealed that&#44; in less than 12&#8239;h&#44; most patients were discharged to their home &#40;65&#46;65&#37;&#41;&#44; a rate much higher than that recorded by other authors &#40;53&#44;50&#37;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> and 58&#46;84&#37;<a class="elsevierStyleCrossRef" href="#bib0070"><span class="elsevierStyleSup">14</span></a>&#41;&#46; The small number of intensive care admissions is shared with other studies&#44;<a class="elsevierStyleCrossRefs" href="#bib0020"><span class="elsevierStyleSup">4&#44;12&#44;15</span></a> which could be related to the early care administered to patients &#40;&#60;12&#8239;h&#41;&#46; The low mortality rate &#40;0&#46;08&#37;&#41; has also been noted in other studies &#40;0&#46;15&#37;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> and 0&#46;19&#37;<a class="elsevierStyleCrossRef" href="#bib0075"><span class="elsevierStyleSup">15</span></a>&#41;&#46;</p><p id="par0105" class="elsevierStylePara elsevierViewall">In terms of differences by sex&#44; this study&#8217;s data indicate that men have a higher prevalence of poisoning than women &#40;55&#46;77&#37; vs&#46; 44&#46;23&#37;&#41;&#46; These data are consistent with that of other studies&#44; such as the one conducted by Carpintero et al&#46; in La Rioja &#40;Spain&#41; in 1998<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">11</span></a> but differ from those of the study by Gonz&#225;lez-Fern&#225;ndez et al&#46; in Asturias &#40;Spain&#41; in 2007<a class="elsevierStyleCrossRef" href="#bib0075"><span class="elsevierStyleSup">15</span></a> in which the differences were greater &#40;66&#46;80&#37; vs&#46; 33&#46;20&#37;&#41; and those of the recently published study by Puiguriguer-Ferrando et al&#46; in the Balearic Islands in which the rates were similar &#40;50&#46;64&#37; vs&#46; 49&#46;36&#37;&#41;&#46; The results also revealed that alcohol&#44; benzodiazepines&#44; insect bites and illicit drugs &#40;cocaine and cannabis<a class="elsevierStyleCrossRef" href="#bib0090"><span class="elsevierStyleSup">17</span></a>&#41; are the toxins of highest prevalence for both sexes&#44; although men have more recurrences with alcohol&#44; while women have more with benzodiazepines&#46; Burillo<a class="elsevierStyleCrossRef" href="#bib0070"><span class="elsevierStyleSup">14</span></a> reached the same conclusions regarding recurrence&#44; which can occur given the ease in obtaining this type of toxin &#40;alcohol and drugs<a class="elsevierStyleCrossRef" href="#bib0095"><span class="elsevierStyleSup">18</span></a>&#41;&#44; which increases the possibilities of another acute poisoning&#46;</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0085">Conclusions</span><p id="par0110" class="elsevierStylePara elsevierViewall">The number of treated acute poisoning cases depends on the hospital location&#44; such that the urban hospital had the highest prevalence&#44; while the rural hospital recorded the lowest number of cases&#46; This situation is also revealed by the seasonal nature of poisonings&#44; especially in the hospital located in the highly touristic area during the summer&#44; which is therefore subject to significant population variations throughout the year and&#44; conversely&#44; in those that experience a vacation exodus&#46; Alcohol is the main cause of poisonings in all of the hospitals analyzed&#46; Males had a higher number of poisonings than females &#40;in all age ranges&#41;&#44; with alcohol once again the main cause&#46; For women 46 years or older&#44; voluntary poisonings with benzodiazepines exceed the alcohol poisonings&#46; A significant number of patients presented previous poisonings&#44; especially men due to alcohol and women due to benzodiazepines&#46; Cocaine was the most consumed illicit drug&#46; These types of events were mostly treated by hospital EDs&#44; and most patients were discharged within the first 12&#8239;h&#46; Finally&#44; the considerable social roots of alcohol consumption for all major age groups should therefore impel us to seek measures to reduce this type of consumption&#46;</p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0090">Conflicts of interest</span><p id="par0115" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflicts of interest&#46;</p></span></span>"
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        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Objective</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">To assess the characteristics of acute poisoning cases treated in hospital emergency departments over 5 years&#46;</p></span> <span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Methods</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Retrospective study of acute poisoning cases treated in 3 hospitals between 2013 and 2017 and an analysis of the demographic characteristics&#44; types of poisoning&#44; seasonal variations&#44; care received and recurrence&#46;</p></span> <span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Results</span><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Some 0&#46;51&#37; of all cases treated in the 3 hospitals corresponded to acute poisoning&#46; The percentages varied by hospital location &#40;0&#46;91&#37; urban&#44; 0&#46;37&#37; coastal and 0&#46;22&#37; rural&#41;&#46; Cases of alcohol poisoning had a seasonal character&#44; increasing during the summer on the coast &#40;p&#8239;&#60;&#8239;&#46;05&#41;&#46; There were differences in the type of poisoning &#40;p&#8239;&#60;&#8239;&#46;05&#41; for patients 31 years of age and older in the 3 hospitals&#46; Alcohol represented the largest number of cases in patients 31 years of age and older&#44; except in the rural area where most cases were due to voluntary poisoning in attempted suicide&#46; Men had a higher prevalence of poisoning than women &#40;55&#46;77&#37; vs&#46; 44&#46;23&#37;&#41; for all cases&#46; Alcohol poisoning was in first place for men 30&#8211;75 years&#44; and voluntary poisoning for attempted suicide was first for women&#44; except for those 30&#8211;46 years of age for whom alcohol was also number one&#46; The large number of cases of recurrence were due to alcohol in men &#40;791 cases&#41; and to benzodiazepines in women &#40;528 cases&#41;&#46;</p></span> <span id="abst0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Conclusions</span><p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">The number of cases and the type of poisoning varied according to hospital location&#44; season&#44; patient sex and patient age&#46;</p></span>"
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        "resumen" => "<span id="abst0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Objetivo</span><p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">Evaluar las caracter&#237;sticas de las intoxicaciones agudas atendidas en urgencias hospitalarias durante cinco a&#241;os&#46;</p></span> <span id="abst0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">M&#233;todo</span><p id="spar0060" class="elsevierStyleSimplePara elsevierViewall">Estudio retrospectivo de las intoxicaciones agudas asistidas en tres hospitales entre 2013 y 2017 y an&#225;lisis de las caracter&#237;sticas demogr&#225;ficas&#44; tipos de intoxicaci&#243;n&#44; variaciones estacionales&#44; asistencia recibida y reincidencia&#46;</p></span> <span id="abst0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Resultados</span><p id="spar0065" class="elsevierStyleSimplePara elsevierViewall">El 0&#44;51&#37; de los casos atendidos en los tres hospitales se correspondieron a intoxicaciones agudas&#46; Los porcentajes var&#237;an seg&#250;n la localizaci&#243;n del hospital &#40;0&#44;91&#37; urbano&#44; 0&#44;37&#37; en zona de costa y 0&#44;22&#37; rural&#46; Las intoxicaciones alcoh&#243;licas presentan cierto car&#225;cter estacional&#44; aumentando en &#233;poca estival en la costa &#40;<span class="elsevierStyleItalic">p</span>&#8239;&#60;&#8239;0&#44;05&#41;&#46; A partir de los 31 a&#241;os de edad existen diferencias en cuanto al tipo de intoxicaci&#243;n &#40;<span class="elsevierStyleItalic">p</span>&#8239;&#60;&#8239;0&#44;05&#41; en los 3 hospitales&#46; El alcohol siempre representa el mayor n&#250;mero de casos a partir de los 31 a&#241;os&#44; excepto en la zona rural que son las intoxicaciones voluntarias con fines autol&#237;ticos&#46; Los hombres muestran mayor prevalencia que las mujeres &#40;55&#44;77&#37; vs 44&#44;23&#37;&#41; para el conjunto de los casos&#46; Las intoxicaciones alcoh&#243;licas est&#225;n en primer lugar en hombres de 30 a 75 a&#241;os y las voluntarias con fines autol&#237;ticos en mujeres&#44; excepto de 30 a 46 a&#241;os que tambi&#233;n es por alcohol&#46; El mayor n&#250;mero de casos reincidentes se producen por el alcohol en hombres &#40;791 casos&#41; y por benzodiacepinas en mujeres &#40;528 casos&#41;&#46;</p></span> <span id="abst0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Conclusiones</span><p id="spar0070" class="elsevierStyleSimplePara elsevierViewall">El n&#250;mero y el tipo de intoxicaci&#243;n var&#237;a en funci&#243;n de la ubicaci&#243;n del hospital&#44; la &#233;poca del a&#241;o&#44; el sexo y la edad de los pacientes&#46;</p></span>"
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                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Emergencies treated&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Poisonings&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Emergencies treated&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">69&#44;075&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">Sting&#47;Bites&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t">Gases&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">Medication ns&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t">Benzodiazepines&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t">Antidepressants&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t">Antihypertensives&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">&#46;769&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t">Paracetamol&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">9&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">81&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">&#46;995&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Insulin&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">31&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t">Anticoagulants&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t">19&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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ISSN: 22548874
Original language: English
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