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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Galeano et al&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a> describen una cohorte de pacientes con trombosis de senos venosos cerebrales &#40;TSVC&#41;&#46; Analizan las complicaciones mediante un evento compuesto&#44; observando que el edema cerebral y el tratamiento con corticoides se asocian a m&#225;s complicaciones&#44; y la cefalea y la afectaci&#243;n del seno sagital superior a menor riesgo de las mismas&#46; En la literatura estas caracter&#237;sticas no se consideran predictoras de peor pron&#243;stico o de secuelas&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">La mortalidad precoz en las TSVC es producida generalmente por una herniaci&#243;n cerebral transtentorial debido a lesiones ocupantes de espacio de gran tama&#241;o o edema cerebral generalizado&#46; La mortalidad a largo plazo se debe principalmente a una enfermedad subyacente &#8211;especialmente c&#225;ncer&#8211;&#44; a complicaciones hemorr&#225;gicas asociadas al tratamiento anticoagulante o a recidivas tromb&#243;ticas&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">El estudio internacional de trombosis venosa cerebral &#40;ISCVT&#41;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">2</span></a> identific&#243; los siguientes factores de mal pron&#243;stico en pacientes con TSVC&#58; edad mayor a 37 a&#241;os&#44; g&#233;nero masculino&#44; situaci&#243;n de coma&#44; la presencia de hemorragia intracraneal&#44; infecci&#243;n del sistema nervioso central&#44; neoplasia y la afectaci&#243;n profunda del sistema venoso cerebral&#46; En una revisi&#243;n sistem&#225;tica<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">3</span></a> se objetiv&#243; asociaci&#243;n entre la persistencia de oclusi&#243;n venosa y peor resultado funcional&#46; Probablemente Galeano et al<span class="elsevierStyleItalic">&#46;</span><a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a> no encontraron estos hallazgos por el reducido tama&#241;o muestral de su cohorte&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">Otro aspecto interesante a tener en cuenta en los pacientes con TSVC&#44; es que aunque aproximadamente el 80&#37; de estos se recuperan sin discapacidad funcional&#44; muchos presentan a largo plazo cefalea cr&#243;nica<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">4</span></a>&#44; d&#233;ficits neuropsicol&#243;gicos o depresi&#243;n&#44; y la sensaci&#243;n de aislamiento por ser un superviviente joven de un &#171;ictus&#187;&#44; con impacto negativo en su d&#237;a a d&#237;a<a class="elsevierStyleCrossRefs" href="#bib0035"><span class="elsevierStyleSup">2&#44;5</span></a>&#46; Quiz&#225; podr&#237;an desarrollarse en futuros estudios escalas de s&#237;ntomas&#44; tanto f&#237;sicos como psicol&#243;gicos&#44; durante el seguimiento que ayuden a identificar las secuelas m&#225;s importantes que afectan a la calidad de vida tras una TSVC&#46;</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflicto de intereses</span><p id="par0025" class="elsevierStylePara elsevierViewall">La autora declara no tener ning&#250;n conflicto de intereses&#46;</p></span></span>"
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Comentario al artículo «Trombosis venosa cerebral en adultos: cohorte de 35 casos de un hospital terciario»
Comments to the article: «Cerebral venous thrombosis in adults: A case series of 35 patients from a tertiary hospital»
A. Gil-Díaza,b
a Servicio de Medicina Interna, Hospital Universitario de Gran Canaria Doctor Negrín, Las Palmas de Gran Canaria, España
b Departamento de Ciencias Médicas y Quirúrgicas, Universidad de Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, España
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Información del artículo
ISSN: 00142565
Idioma original: Español
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