Ketone elevation during SGLT2 inhibitor therapy is driven by acute illness rather than treatment indication

Constanti, M.; Liakopoulos, V.; Kotsa, K.; Koufakis, T.

doi:10.1016/j.rceng.2026.502565

Revista Clínica Española (English Edition)

ISSN: 2254-8874

Revista Clínica Española published its first issue in 1940 and is the body of expression of the Spanish Society of Internal Medicine (SEMI).
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Ketone elevation during SGLT2 inhibitor therapy is driven by acute illness rather than treatment indication

La elevación de cetonas durante el tratamiento con inhibidores de SGLT2 está impulsada por la enfermedad aguda más que por la indicación terapéutica

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M. Constantia, V. Liakopoulosb, K. Kotsac, T. Koufakisd,

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thkoyfak@hotmail.com

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a Medical School, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece

b 2nd Department of Nephrology, AHEPA University Hospital Medical School, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece

c Division of Endocrinology and Metabolism and Diabetes Center, First Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, AHEPA University Hospital, 54636 Thessaloniki, Greece

d Second Propaedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, Hippokration General Hospital, 54642 Thessaloniki, Greece

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Ketone elevation during SGLT2 inhibitor therapy is driven by acute illness rather than treatment indication

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