Revista Clínica Española (English Edition) Revista Clínica Española (English Edition)
Clinical application of cell, gene and tissue therapies in Spain
Aplicación clínica de las terapias con células, genes y tejidos en España
P. Gálvez-Martín, , A. Ruiz, B. Clares
Departamento de Farmacia y Tecnología Farmacéutica, Facultad de Farmacia, Universidad de Granada, Granada, Spain
Received 28 June 2017, Accepted 13 August 2017

Scientific and technical advances in the areas of biomedicine and regenerative medicine have enabled the development of new treatments known as “advanced therapies”, which encompass cell therapy, genetics and tissue engineering. The biologic products that can be manufactured from these elements are classified from the standpoint of the Spanish Agency of Medication and Health Products in advanced drug therapies, blood products and transplants. This review seeks to provide scientific and administrative information for clinicians on the use of these biologic resources.


Los avances científicos y técnicos en el área biomédica y la medicina regenerativa han permitido el desarrollo de nuevos tratamientos, denominados «terapias avanzadas», que engloban la terapia celular, la génica y la ingeniería tisular. Los productos biológicos que pueden fabricarse a partir de estos elementos se clasifican desde el punto de vista de la Agencia Española del Medicamento y Productos Sanitarios en medicamentos de terapias avanzadas, productos derivados de la sangre y trasplantes. Esta revisión pretende aportar información científica y administrativa, de utilidad para el clínico, sobre el uso de estos recursos biológicos.

Stem cells, Cell therapy, Gene therapy, Tissue engineering, Advanced therapies, Regenerative medicine
Palabras clave
Célula madre, Terapia celular, Terapia génica, Ingeniería tisular, Terapias avanzadas, Medicina regenerativa


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