Revista Clínica Española (English Edition) Revista Clínica Española (English Edition)
Special article
Clinical trials. A pending subject
Ensayos clínicos. Una asignatura pendiente
B. Gil-Extremera, , P. Jiménez-López, J.D. Mediavilla-García
Departamento de Medicina, Universidad de Granada, Granada, Spain
Received 30 March 2017, Accepted 29 June 2017

Clinical trials are essential tools for the progress of clinical medicine in its diagnostic and therapeutic aspects. Since the first trial in 1948, which related tobacco use with lung cancer, there have been more than 150,000 clinical trials to date in various areas (pediatrics, cardiology, oncology, endocrinology, etc.). This article highlights the importance for all physicians to participate, over the course of their professional career, in a clinical trial, due to the inherent benefits for patients, the progress of medicine and for curricular prestige. The authors have created a synthesis of their experience with clinical trials on hypertension, diabetes, dyslipidemia and ischemic heart disease over the course of almost 3 decades. Furthermore, a brief reference has been made to the characteristics of a phase I unit, as well as to a number of research studies currently underway.


Los ensayos clínicos son una herramienta fundamental para el avance de la medicina clínica en sus vertientes diagnóstica y terapéutica. Desde la aparición del primer ensayo en 1948, que relacionaba el tabaco con el cáncer de pulmón, se han realizado hasta la fecha más de 150.000 en diversas áreas (pediatría, cardiología, oncología, endocrinología, etc.). Este artículo resalta la importancia para todo facultativo de participar, a lo largo de su trayectoria profesional, en algún ensayo clínico por los beneficios inherentes al paciente, al progreso de la medicina, así como al prestigio curricular. Los autores hacen una síntesis de su experiencia sobre ensayos clínicos en hipertensión, diabetes, dislipidemias y cardiopatía isquémica a lo largo de casi 3 décadas. Asimismo, se hace una breve referencia a las características de una unidad en fase i, así como a algunas investigaciones que actualmente se están realizando.

Clinical trial, Hypertension, Diabetes, Dyslipidaemia
Palabras clave
Ensayo clínico, Hipertensión, Diabetes, Dislipidemias


To access the full text of the publication Revista Clínica Española (English Edition) you need to be a subscriber or member of the Sociedad Española de Medicina Interna.

  • If you are a member of the Sociedad Española de Medicina Interna::
    1.- You must go to the following address
    2.- Authenticate as a member of the SEMI. You must use your login details
    3.- Access to the contents of Revista Clínica Española

  • If you are a subscriber:
    Can you recover your data in the "I Forgot my Password" button on the right sidebar of this website.

Cookies Policy
To improve our services and products, we use cookies (own or third parties authorized) to show advertising related to client preferences through the analyses of navigation customer behavior. Continuing navigation will be considered as acceptance of this use. You can change the settings or obtain more information by clicking here.