Revista Clínica Española (English Edition) Revista Clínica Española (English Edition)
Rev Clin Esp 2018;218:149-55 - Vol. 218 Num.3 DOI: 10.1016/j.rceng.2017.10.001
Malignancies and infection due to the human immunodeficiency virus. Are these emerging diseases?
Neoplasias e infección por el virus de la inmunodeficiencia humana: ¿enfermedades emergentes?
M.E. Valencia Ortega
Servicio de Medicina Interna-Unidad de VIH, Hospital Universitario La Paz, Madrid, Spain
Received 21 May 2017, Accepted 30 July 2017

Since the start of the human immunodeficiency virus (HIV) epidemic, tumor disease among patients has been significant. The collection of malignancies can be divided primarily into 2 groups: those associated with HIV (all of which are related to viral diseases) and those not associated with HIV (only some of which are associated with viral diseases).

The origin of these malignancies is multifactorial, and the main causes that have led to an increase in tumor disease are immunosuppression, coinfection with oncogenic viruses and life prolongation secondary to the use of antiretroviral therapy.

Establishing the general characteristics of the undiagnosed AIDS tumors is difficult, mainly because they are a highly heterogeneous group formed by malignancies of a diverse nature. The treatments do not differ from those used in the general population, although the management can be more difficult due to the late diagnosis, drug interactions and associated comorbidities.


Desde los inicios de la epidemia del virus de la inmunodeficiencia humana (VIH), la patología tumoral ha sido muy importante. El conjunto de las neoplasias se puede dividir básicamente en 2 grupos: las asociadas al VIH, todas ellas relacionadas con enfermedades virales, y las no asociadas al VIH, entre las que algunas están asociadas a enfermedades virales y otras no.

El origen es multifactorial y las principales causas que han llevado a que se produzca un aumento de la patología tumoral son la inmunodepresión, la coinfección con virus oncogénicos y la prolongación de la vida secundaria al uso de tratamiento antirretroviral.

Establecer las características generales de los tumores no diagnósticos de sida es difícil fundamentalmente porque son un grupo muy heterogéneo formado por neoplasias de diversa índole. Los tratamientos no difieren de los empleados en la población general, aunque el manejo puede ser más difícil por el diagnóstico tardío, las interacciones medicamentosas y las comorbilidades asociadas.

Undiagnosed AIDS tumors, Malignancies and HIV, Mortality
Palabras clave
Tumores no diagnósticos de sida, Neoplasias y VIH, Mortalidad


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Rev Clin Esp 2018;218:149-55 - Vol. 218 Num.3 DOI: 10.1016/j.rceng.2017.10.001
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