TY - JOUR T1 - Treatment and prevention of invasive pneumococcal disease JO - Revista Clínica Española (English Edition) T2 - AU - Domínguez-Alegría,A.R. AU - Pintado,V. AU - Barbolla,I. SN - 22548874 M3 - 10.1016/j.rceng.2018.01.004 DO - 10.1016/j.rceng.2018.01.004 UR - https://revclinesp.es/en-treatment-prevention-invasive-pneumococcal-disease-articulo-S2254887418300250 AB - Invasive pneumococcal disease is a severe infection that mainly affects patients with associated comorbidity. The pediatric conjugate vaccination has resulted in a change in the adult vaccination strategy. The antibiotic resistance of pneumococcus is not currently a severe problem. Nevertheless, the World Health Organisation has included pneumococcus among the bacteria whose treatment requires the introduction of new drugs, such as ceftaroline and ceftobiprole. Although the scientific evidence is still limited, the combination of beta-lactams and macrolides is recommended as empiric therapy for bacteraemic pneumococcal pneumonia. ER -