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Vol. 218. Num. 4.May 2018
Pages 163-214
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Vol. 218. Num. 4.May 2018
Pages 163-214
Review
DOI: 10.1016/j.rceng.2017.08.002
Clinical application of cell, gene and tissue therapies in Spain
Aplicación clínica de las terapias con células, genes y tejidos en España
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P. Gálvez-Martín
Corresponding author
galmafarma@gmail.com

Corresponding author.
, A. Ruiz, B. Clares
Departamento de Farmacia y Tecnología Farmacéutica, Facultad de Farmacia, Universidad de Granada, Granada, Spain
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Table 1. Properties, limitations and ethical problems of the various types of stem cells in cell therapy.
Table 2. Advanced therapy drugs authorized in Spain.
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Abstract

Scientific and technical advances in the areas of biomedicine and regenerative medicine have enabled the development of new treatments known as “advanced therapies”, which encompass cell therapy, genetics and tissue engineering. The biologic products that can be manufactured from these elements are classified from the standpoint of the Spanish Agency of Medication and Health Products in advanced drug therapies, blood products and transplants. This review seeks to provide scientific and administrative information for clinicians on the use of these biologic resources.

Keywords:
Stem cells
Cell therapy
Gene therapy
Tissue engineering
Advanced therapies
Regenerative medicine
Resumen

Los avances científicos y técnicos en el área biomédica y la medicina regenerativa han permitido el desarrollo de nuevos tratamientos, denominados «terapias avanzadas», que engloban la terapia celular, la génica y la ingeniería tisular. Los productos biológicos que pueden fabricarse a partir de estos elementos se clasifican desde el punto de vista de la Agencia Española del Medicamento y Productos Sanitarios en medicamentos de terapias avanzadas, productos derivados de la sangre y trasplantes. Esta revisión pretende aportar información científica y administrativa, de utilidad para el clínico, sobre el uso de estos recursos biológicos.

Palabras clave:
Célula madre
Terapia celular
Terapia génica
Ingeniería tisular
Terapias avanzadas
Medicina regenerativa

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